Proceedings

2019

  • Kolb, J P;Weng, D;Hakert, H;Eibl, M;Draxinger, W;Meyer, T;Gottschall, T;Brinkmann, R;Birngruber, R;Popp, J;Limpert, J;Karpf, S and Huber, R: Virtual HE histology by fiber-based picosecond two-photon microscopy. in Multiphoton Microscopy in the Biomedical Sciences XIX Proc. SPIE,10882, pp. 108822F, International Society for Optics and Photonics, 2019
    BibTeX Link
    @inproceedings{Kolb2019/2,
       author = {Kolb, J P;Weng, D;Hakert, H;Eibl, M;Draxinger, W;Meyer, T;Gottschall, T;Brinkmann, R;Birngruber, R;Popp, J;Limpert, J;Karpf, S and Huber, R},
       title = {Virtual HE histology by fiber-based picosecond two-photon microscopy},
       booktitle = {Multiphoton Microscopy in the Biomedical Sciences XIX} {Proc. SPIE,10882},
       editor = {Ammasi Periasamy; Peter T. C. So; Karsten König},
       publisher = { International Society for Optics and Photonics},
       year = {2019},
       pages = {108822F},
    keywords = {AG-Huber_NL},
       
    doi = {10.1117/12.2507866},
       type = {Conference Proceedings}
    }
    
  • Detrez, N;Miura, Y;Seifert, E;Theisen-Kunde, D and Brinkmann, R: Heating and optoacoustic temperature determination of cell cultures. in Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, no. 11079, SPIE, 2019
    BibTeX Link
    @inproceedings{Detrez2019,
       author = {Detrez, N;Miura, Y;Seifert, E;Theisen-Kunde, D and Brinkmann, R},
       title = {Heating and optoacoustic temperature determination of cell cultures},
       publisher = {SPIE},
       volume = {11079},
       series = {European Conferences on Biomedical Optics},
    booktitle =    {Proc. SPIE 11079, Medical Laser Applications
    and Laser-Tissue Interactions IX},
       url = {https://doi.org/10.1117/12.2527024},
    keywords = {Laser, Noninvasive thermometry, hyperthermia, temperature measurement, photoacoustics}, optoacoustics,
       year = {2019},
       type = {Conference Proceeding}
    }
    
  • Bliedtner,K; Seifert, E and Brinkmann,R: Dosimetry for microsecond selective laser trabeculoplasty. in Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, no. 11079, 2019
    BibTeX Link
    @inproceedings{Bliedtner2019,
       author = {Bliedtner,K; Seifert, E and Brinkmann,R},
       title = {Dosimetry for microsecond selective laser trabeculoplasty},
       volume = {11079},
       DOI = {10.1117/12.2526987},
       year = {2019},
    keywords = {Ophthalmology, ophthalmic optics and devices, selective laser trabeculoplasty, micro bubble detection},
    booktitle =    {Proc. SPIE 11079, Medical Laser Applications
    and Laser-Tissue Interactions IX},
       type = {Conference proceedings}
    }
    
  • Ahrens, M; Idel, C; Chaker, A; Wollenberg, B; König, P; Schulz-Hildebrandt, H and Hüttmann, G: An endomicroscopic OCT for clinical trials in the field of ENT (Invited). in Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II, pp. 1-4, 2019
    BibTeX Link
    @inproceedings{Ahrens2019,
    title = {An endomicroscopic OCT for clinical trials in the field of ENT (Invited)},
    author = { Ahrens, M; Idel, C; Chaker, A; Wollenberg, B; K\"{o}nig, P; Schulz-Hildebrandt, H and H\"{u}ttmann, G},
    url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11073/2527099/An-endomicroscopic-OCT-for-clinical-trials-in-the-field-of/10.1117/12.2527099.full},
    
    isbn = {9781510628397},
    year = {2019},
    date = {2019-01-01},
    booktitle = {Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II},
    number = {110730U},
    pages = {1--4},
    keywords = {Endoskope, meos, OCM},
    pubstate = {published},
    tppubtype = {inproceedings}
    }
  • Münter, M; Schulz-Hildebrandt, H; Pieper, M; König, P and Hüttmann, G: 4D microscopic optical coherence tomography imaging of ex vivo mucus transport. in Proc. SPIE 11078, Optical Coherence Imaging Techniques and Imaging in Scattering Media III, no. 11078, pp. 1-5, 2019
    BibTeX Link
    @inproceedings{Muenter2019,
    title = {4D microscopic optical coherence tomography imaging of ex vivo mucus transport},
    author = { M\"{u}nter, M; Schulz-Hildebrandt, H; Pieper, M; K\"{o}nig, P and  H\"{u}ttmann, G},
    url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11078/2527138/4D-microscopic-optical-coherence-tomography-imaging-of-ex-vivo-mucus/10.1117/12.2527138.full},
    
    isbn = {9781510628496},
    year = {2019},
    date = {2019-01-01},
    booktitle = {Proc. SPIE 11078, Optical Coherence Imaging Techniques and Imaging in Scattering Media III},
    volume = {11078},
    number = {11},
    pages = {1--5},
    keywords = {OCM},
    pubstate = {published},
    tppubtype = {inproceedings}
    }

2018

  • Schmidt, M. and Pfeiffer, T. and Grill, C. and Huber, R. and Jirauschek, C.: Self-Stabilization Mechanism in Fourier Domain Mode-Locked (FDML) Lasers. in EPS-QEOD Europhoton Conference Solid State, Fibre, and Waveguide Coherent Light Sources, European Physical Society EPS, 2018
    BibTeX Link
    @inproceedings{Schmidt2018,
    	author = {Schmidt, M. and  Pfeiffer, T. and  Grill, C. and  Huber, R. and  Jirauschek, C.}, 
    	title = {Self-Stabilization Mechanism in Fourier Domain Mode-Locked (FDML) Lasers},
    	booktitle = {EPS-QEOD Europhoton Conference Solid State, Fibre, and Waveguide Coherent Light Sources},
    	publisher = {European Physical Society EPS},
    	year = {2018},
    keywords = {AG-Huber_FDML},
    	language = {en},
    	url = {http://www.europhoton.org/},
    }
  • Smits, J; Ourak, M; Gijbels, A; Esteveny, L; Borghesan, G; Schoevaerdts, L; Willekens; Stalmans, P; Lankenau, E; Schulz-Hildebrandt, H; Hüttmann, G; Reynaerts, D and Vander Poorten, E.B: Development and Experimental Validation of a Combined FBG Force and OCT Distance Sensing Needle for Robot-Assisted Retinal Vein Cannulation. 2018 IEEE Intern Conf Robot a Automation (ICRA), pp. 129-134, 2018
    BibTeX Link
    @inproceedings{Smits2018,
    title = {Development and Experimental Validation of a Combined FBG Force and OCT Distance Sensing Needle for Robot-Assisted Retinal Vein Cannulation},
    author = {Smits, J; Ourak, M; Gijbels, A;  Esteveny, L; Borghesan, G; Schoevaerdts, L; Willekens; Stalmans, P; Lankenau, E; Schulz-Hildebrandt, H; H\"{u}ttmann, G; Reynaerts, D and  Vander Poorten, E.B},
    
    doi = {10.1109/ICRA.2018.8460983},
    year = {2018},
    date = {2018-09-20},
    journal = {2018 IEEE Intern Conf Robot a Automation (ICRA)},
    pages = {129-134},
    abstract = {Retinal Vein Occlusion is a common retinal vascular disorder which can cause severe loss of vision. Retinal vein cannulation followed by injection of an anti-coagulant into the affected vein is a promising treatment. However, given the scale and fragility of the surgical workfield, this procedure is considered too high-risk to perform manually. A first successful robot-assisted procedure has been demonstrated. Even though successful, the procedure remains extremely challenging. This paper aims at providing a solution for the limited perception of instrument-tissue interaction forces as well as depth estimation during retinal vein cannulation. The development of a novel combined force and distance sensing cannulation needle relying on Fiber Bragg grating (FBG) and Optical Coherence Tomography (OCT) A-scan technology is reported. The design, the manufacturing process, the calibration method, and the experimental characterization of the produced sensor are discussed. 
    The functionality of the combined sensing modalities and the real-time distance estimation algorithm are validated respectively on in-vitro and ex-vivo models.},
    keywords = {Endoskope},
    pubstate = {published},
    tppubtype = {inproceedings}
    }
  • Schulz-Hildebrandt,H; Münter, M; Ahrens,M; Spahr, H; Hillmann, D; König, P and Hüttmann, G: Coherence and diffraction limited resolution in microscopic OCT by a unified approach for the correction of dispersion and aberrations. in 2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources, no. 10591, pp. 105910O, 2018
    BibTeX Link
    @inproceedings{Schulz-Hildebrandt2018a,
    title = {Coherence and diffraction limited resolution in microscopic OCT by a unified approach for the correction of dispersion and aberrations},
    author = {Schulz-Hildebrandt,H; M\"{u}nter, M; Ahrens,M; Spahr, H; Hillmann, D; K\"{o}nig, P and  H\"{u}ttmann, G},
    doi = {10.1117/12.2303755},
    isbn = {9781510616745},
    year = {2018},
    date = {2018-03-05},
    booktitle = {2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources},
    volume = {10591},
    pages = {105910O},
    abstract = {Optical coherence tomography (OCT) images scattering tissues with 5 to 15 μm resolution. This is usually not sufficient for a distinction of cellular and subcellular structures. Increasing axial and lateral resolution and compensation of artifacts caused by dispersion and aberrations is required to achieve cellular and subcellular resolution. This includes defocus which limit the usable depth of field at high lateral resolution. OCT gives access the phase of the scattered light and hence correction of dispersion and aberrations is possible by numerical algorithms. Here we present a unified dispersion/aberration correction which is based on a polynomial parameterization of the phase error and an optimization of the image quality using Shannon’s entropy. For validation, a supercontinuum light sources and a costume-made spectrometer with 400 nm bandwidth were combined with a high NA microscope objective in a setup for tissue and small animal imaging. Using this setup and computation corrections, volumetric imaging at 1.5 μm resolution is possible. Cellular and near cellular resolution is demonstrated in porcine cornea and the drosophila larva, when computational correction of dispersion and aberrations is used. Due to the excellent correction of the used microscope objective, defocus was the main contribution to the aberrations. In addition, higher aberrations caused by the sample itself were successfully corrected. Dispersion and aberrations are closely related artifacts in microscopic OCT imaging. Hence they can be corrected in the same way by optimization of the image quality. This way microscopic resolution is easily achieved in OCT imaging of static biological tissues.},
    keywords = {OCM},
    pubstate = {published},
    tppubtype = {inproceedings}
    }

2017

  • Eibl, Matthias and Karpf, Sebastian and Hakert, Hubertus and Weng, Daniel and Huber, Robert: Two-photon-excited fluorescence (TPEF) and fluorescence lifetime imaging (FLIM) with sub-nanosecond pulses and a high analog bandwidth signal detection. in Proc. SPIE, no. 10069, pp. 100691F-6, 2017
    BibTeX Link
    @inproceedings{Eibl2017,
       author = {Eibl, Matthias and Karpf, Sebastian and Hakert, Hubertus and Weng, Daniel and Huber, Robert},
       title = {Two-photon-excited fluorescence (TPEF) and fluorescence lifetime imaging (FLIM) with sub-nanosecond pulses and a high analog bandwidth signal detection},
    booktitle = {Proc. SPIE },
       volume = {10069},
       pages = {100691F-6},
       doi= {10.1117/12.2250831},
      year={2017},
    keywords = {AG-Huber_NL},
       type = {Conference Proceedings}
    }
    
  • Hakert, H; Eibl, M; Karpf, S and Huber, R: Sparse-sampling with time-encoded (TICO) stimulated Raman scattering for fast image acquisition. in Proc. SPIE 10414, pp. 1041408-1041408-7, 2017
    BibTeX Link
    @inproceedings{Hakert2017,
       author = {Hakert, H; Eibl, M; Karpf, S and Huber, R},
       title = {Sparse-sampling with time-encoded (TICO) stimulated Raman scattering for fast image acquisition},
    booktitle = {Proc. SPIE} {10414},
    Year={2017},
       
       pages = {1041408-1041408-7},
       url = {http://dx.doi.org/10.1117/12.2287947},
    keywords = {AG-Huber_NL},
       type = {Conference Proceedings}
    }
    
  • Eibl, M; Karpf, S; Hakert, H; Weng, D; Pfeiffer, T; Kolb, J P and Huber, R: Single pulse two-photon fluorescence lifetime imaging (SP-FLIM) with MHz pixel rate and an all fiber based setup. in Proc. SPIE 10414, pp. 1041403-1041403-7, 2017
    BibTeX Link
    @inproceedings{Eibl2017,
       author = {Eibl, M; Karpf, S; Hakert, H; Weng, D; Pfeiffer, T; Kolb, J P and Huber, R},
       title = {Single pulse two-photon fluorescence lifetime imaging (SP-FLIM) with MHz pixel rate and an all fiber based setup},
      booktitle = {Proc. SPIE} {10414},
      
      year = {2017},
    keywords = {AG-Huber_NL},
       pages = {1041403-1041403-7},
       url = {http://dx.doi.org/10.1117/12.2286035},
       type = {Conference Proceedings}
    }
    
  • Wang, Tianshi and Pfeiffer, Tom and Wu, Min and Wieser, Wolfgang and Draxinger, Wolfgang and van der Steen, Antonius F. W. and Huber, Robert and van Soest, Gijs: Short pulse laser induced thermo-elastic deformation imaging. in Proc. SPIE, no. 10062, pp. 100620C-100620C-4, 2017
    BibTeX Link
    @inproceedings{Wang2017,
       author = {Wang, Tianshi and Pfeiffer, Tom and Wu, Min and Wieser, Wolfgang and Draxinger, Wolfgang and van der Steen, Antonius F. W. and Huber, Robert and van Soest, Gijs},
       title = {Short pulse laser induced thermo-elastic deformation imaging},
    booktitle = Proc. SPIE},
      volume = {10062},
      year = {2017},
       pages = {100620C-100620C-4},
      url = {http://dx.doi.org/10.1117/12.2251502},
    keywords = {AG-Huber_OCT},
       type = {Conference Proceedings}
    }
    
    
  • Eibl, Matthias and Karpf, Sebastian and Hakert, Hubertus and Weng, Daniel and Blömker, Torben and Huber, Robert: Pulse-to-pulse wavelength switching of diode based fiber laser for multi-color multi-photon imaging. in Proc. SPIE, no. 10083, pp. 100831C-6, 2017
    BibTeX Link
    @inproceedings{Eibl2017,
       author = {Eibl, Matthias and Karpf, Sebastian and Hakert, Hubertus and Weng, Daniel and Blömker, Torben and Huber, Robert},
       title = {Pulse-to-pulse wavelength switching of diode based fiber laser for multi-color multi-photon imaging},
    booktitle = {Proc. SPIE },
       volume = {10083},
       pages = {100831C-6},
       year= {2017},
       doi= {10.1117/12.2251965},
    keywords = {AG-Huber_NL},
       type = {Conference Proceedings}
    }
    
  • Pfeiffer, T; Draxinger, W; Grill, C and Huber, R: Long-range live 3D-OCT at different spectral zoom levels. in Proc. SPIE 10416, pp. 104160L1-4, 2017
    BibTeX
    @inproceedings{Pfeiffer2017,
       author = {Pfeiffer, T; Draxinger, W; Grill, C and Huber, R},
       title = {Long-range live 3D-OCT at different spectral zoom levels},
       booktitle = {Proc. SPIE} {10416},
      
       pages = {104160L1-4},
       year = {2017},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
       type = {Conference Proceedings}
    }
    
  • Laves, Max-Heinrich and Schoob, Andreas and Kahrs, Lüder A. and Pfeiffer, Tom and Huber, Robert and Ortmaier, Tobias: Feature tracking for automated volume of interest stabilization on 4D-OCT images. in Proc. SPIE, no. 10135, pp. 101350W-101350W-7, 2017
    BibTeX Link
    @inproceedings{Laves2017,
       author = {Laves, Max-Heinrich and Schoob, Andreas and Kahrs, Lüder A. and Pfeiffer, Tom and Huber, Robert and Ortmaier, Tobias},
       title = {Feature tracking for automated volume of interest stabilization on 4D-OCT images},
     booktitle = {Proc. SPIE},
       volume = {10135},
       pages = {101350W-101350W-7},
      year = {2017},
       url = {http://dx.doi.org/10.1117/12.2255090},
    keywords = {AG-Huber_OCT},
       type = {Conference Proceedings}
    }
    
  • Pfeiffer, Tom and Draxinger, Wolfgang and Wieser, Wolfgang and Klein, Thomas and Petermann, Markus and Huber, Robert: Analysis of FDML lasers with meter range coherence. in Proc. SPIE, no. 10053, pp. 100531T-100531T-6, 2017
    BibTeX Link
    @inproceedings{Pfeiffer2017,
       author = {Pfeiffer, Tom and Draxinger, Wolfgang and Wieser, Wolfgang and Klein, Thomas and Petermann, Markus and Huber, Robert},
       title = {Analysis of FDML lasers with meter range coherence},
       booktitle = {Proc. SPIE},
       volume = {10053},
       pages = {100531T-100531T-6},
        url = {http://dx.doi.org/10.1117/12.2254792},
    
      year = {2017},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
       type = {Conference Proceedings}
    }
    
  • Kolb, J P; Klee, J; Pfeiffer, Tand Huber, R: 1060nm FDML laser with centimeter coherence length and 1.67 MHz sweep rate for full eye length and retinal ultra-widefield OCT. in Proc. SPIE 10416, pp. 104160J-104160J-6, 2017
    BibTeX Link
    @inproceedings{Kolb2017,
       author = {Kolb, J P; Klee, J; Pfeiffer, Tand Huber, R},
       title = {1060nm FDML laser with centimeter coherence length and 1.67 MHz sweep rate for full     eye length and retinal ultra-widefield OCT},
      booktitle = {Proc. SPIE} {10416},
    
      pages = {104160J-104160J-6},
      year = {2017},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
       url = {http://dx.doi.org/10.1117/12.2286854},
       type = {Conference Proceedings}
    }
    

2016

  • Strauch, M and Urbach, H P: Surface harmonics on liquid lenses. in 2016 IEEE Photonics Conference (IPC), pp. 248-249, Oct, 2016
    BibTeX Link
    @INPROCEEDINGS{Strauch2017,
    author={Strauch, M and Urbach, H P},
    booktitle={2016 IEEE Photonics Conference (IPC)},
    title={Surface harmonics on liquid lenses},
    year={2016},
    
    pages={248-249},
    keywords={lenses;optical harmonic generation;optical tuning;oscillations;surface harmonics;liquid lenses;tunability;nonspherical surfaces;surface oscillations;Lenses;Liquids;Surface waves;Optical surface waves;Harmonic analysis;Shape;Optical switches},
    doi={10.1109/IPCon.2016.7831063},
    ISSN={},
    month={Oct},}
  • Kolb, Jan Philip and Klein, Thomas and Eibl, Matthias and Pfeiffer, Tom and Wieser, Wolfgang and Huber, Robert: Megahertz FDML laser with up to 143nm sweep range for ultrahigh resolution OCT at 1050nm. in Proc. SPIE, no. 9697, pp. 969703-969703-8, 2016
    BibTeX Link
    @inproceedings{Kolb2016,
       author = {Kolb, Jan Philip and Klein, Thomas and Eibl, Matthias and Pfeiffer, Tom and Wieser, Wolfgang and Huber, Robert},
       title = {Megahertz FDML laser with up to 143nm sweep range for ultrahigh resolution OCT at 1050nm},
       booktitle = {Proc. SPIE},
       volume = {9697},
    
       pages = {969703-969703-8},
       year= { 2016}
       note = {10.1117/12.2214758},
       abstract = {We present a new design of a Fourier Domain Mode Locked laser (FDML laser), which provides a new record in sweep range at ~1μm center wavelength: At the fundamental sweep rate of 2x417 kHz we reach 143nm bandwidth and 120nm with 4x buffering at 1.67MHz sweep rate. The latter configuration of our system is characterized: The FWHM of the point spread function (PSF) of a mirror is 5.6μm (in tissue). Human in vivo retinal imaging is performed with the MHz laser showing more details in vascular structures. Here we could measure an axial resolution of 6.0μm by determining the FWHM of specular reflex in the image. Additionally, challenges related to such a high sweep bandwidth such as water absorption are investigated.},
       url = {http://dx.doi.org/10.1117/12.2214758},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
       type = {Conference Proceedings}
    }
    

2015

  • Karpf, Sebastian and Eibl, Matthias and Wieser, Wolfgang and Klein, Thomas and Huber, Robert: Time-encoded Raman scattering (TICO-Raman) with Fourier domain mode locked (FDML) lasers. in Proc. SPIE, no. 9541, pp. 95410F-95410F-6, 2015
    BibTeX Link
    @inproceedings{HU_2015_Karpf_b,
    author = {Karpf, Sebastian and Eibl, Matthias and Wieser, Wolfgang and Klein, Thomas and Huber, Robert},
    title = { Time-encoded Raman scattering (TICO-Raman) with Fourier domain mode locked (FDML) lasers },
    booktitle = {Proc. SPIE },
    volume = {9541},
    type = {Conference Proceedings},
    pages = {95410F-95410F-6},
    year = {2015},
    keywords = {AG-Huber_NL},
    doi = {10.1117/12.2183859}
    }
  • Karpf, Sebastian and Eibl, Matthias and Huber, Robert: Nanosecond two-photon excitation fluorescence imaging with a multi color fiber MOPA laser. in Proc. SPIE, no. 9536, pp. 953616-953616-5, 2015
    BibTeX Link
    @inproceedings{HU_2015_Karpf_c,
    author = {Karpf, Sebastian and Eibl, Matthias and Huber, Robert},
    title = { Nanosecond two-photon excitation fluorescence imaging with a multi color fiber MOPA laser },
    booktitle = {Proc. SPIE },
    type = {Conference Proceedings},
    volume = {9536},
    pages = {953616-953616-5},
    year = {2015},
    keywords = {AG-Huber_NL},
    doi = {10.1117/12.2183854}
    }
  • Eibl, Matthias and Karpf, Sebastian and Wieser, Wolfgang and Klein, Thomas and Huber, Robert: Hyperspectral stimulated Raman microscopy with two fiber laser sources. in Proc. SPIE, no. 9536, pp. 953604-953604-6, 2015
    BibTeX Link
    @inproceedings{HU_2015_Eibl_a,
    author = {Eibl, Matthias and Karpf, Sebastian and Wieser, Wolfgang and Klein, Thomas and Huber, Robert},
    title = {Hyperspectral stimulated Raman microscopy with two fiber laser sources },
    booktitle = {Proc. SPIE },
    type = {Conference Proceedings},
    volume = {9536},
    pages = {953604-953604-6},
    year = {2015},
    keywords = {AG-Huber_NL},
    doi = {10.1117/12.2183822}
    }
  • Kolb, Jan Philip and Klein, Thomas and Wieser, Wolfgang and Draxinger, Wolfgang and Huber, Robert: High definition in vivo retinal volumetric video rate OCT at 0.6 Giga-voxels per second. in Proc. SPIE, no. 9541, pp. 95410Z-95410Z-8, 2015
    BibTeX Link
    @inproceedings{HU_2015_Kolb_d,
    author = {Kolb, Jan Philip and Klein, Thomas and Wieser, Wolfgang and Draxinger, Wolfgang and Huber, Robert},
    title = {High definition in vivo retinal volumetric video rate OCT at 0.6 Giga-voxels per second },
    booktitle = {Proc. SPIE },
    type = {Conference Proceedings},
    volume = {9541},
    pages = {95410Z-95410Z-8},
    year = {2015},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
    doi = {10.1117/12.2183768}
    }
  • Wieser, Wolfgang and Klein, Thomas and Draxinger, Wolfgang and Huber, Robert: Fully automated 1.5 MHz FDML laser with more than 100mW output power at 1310 nm. in Proc. SPIE, no. 9541, pp. 954116-954116-7, 2015
    BibTeX Link
    @inproceedings{HU_2015_Wieser_a,
    author = {Wieser, Wolfgang and Klein, Thomas and Draxinger, Wolfgang and Huber, Robert},
    title = { Fully automated 1.5 MHz FDML laser with more than 100mW output power at 1310 nm },
    booktitle = {Proc. SPIE },
    type = {Conference Proceedings},
    volume = {9541},
    pages = {954116-954116-7},
    year = {2015},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
    doi = {10.1117/12.2183431}
    }
  • Kolb, Jan Philip and Klein, Thomas and Wieser, Wolfgang and Draxinger, Wolfgang and Huber, Robert: Full volumetric video rate OCT of the posterior eye with up to 195.2 volumes/s. in Proc. SPIE, no. 9312, pp. 931202-931202-7, 2015
    BibTeX Link
    @inproceedings{Kolb2015 ,
       author = {Kolb, Jan Philip and Klein, Thomas and Wieser, Wolfgang and Draxinger, Wolfgang and Huber, Robert },
       title = {Full volumetric video rate OCT of the posterior eye with up to 195.2 volumes/s},
       volume = {9312},
    Year={2015},
       pages = {931202-931202-7 },
       DOI = {10.1117/12.2077147 },
       booktitle = {Proc. SPIE },
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
       type = {Conference Proceedings}
    }
    
  • Pfeiffer, Tom and Wieser, Wolfgang and Klein, Thomas and Petermann, Markus and Kolb, Jan-Phillip and Eibl, Matthias and Huber, Robert: Flexible A-scan rate MHz OCT: computational downscaling by coherent averaging. Proc. SPIE, no. 9697, pp. 96970S-96970S-5, 2015
    BibTeX Link
    @inproceedings{Pfeiffer2016,
       author = {Pfeiffer, Tom and Wieser, Wolfgang and Klein, Thomas and Petermann, Markus and Kolb, Jan-Phillip and Eibl, Matthias and Huber, Robert},
       title = {Flexible A-scan rate MHz OCT: computational downscaling by coherent averaging},
    Year={  2015}
       journal = {Proc. SPIE},
       volume = {9697},
       pages = {96970S-96970S-5},
       note = {10.1117/12.2214788},
       abstract = {In order to realize fast OCT-systems with adjustable line rate, we investigate averaging of image data from an FDML based MHz-OCT-system. The line rate can be reduced in software and traded in for increased system sensitivity and image quality. We compare coherent and incoherent averaging to effectively scale down the system speed of a 3.2 MHz FDML OCT system to around 100 kHz in postprocessing. We demonstrate that coherent averaging is possible with MHz systems without special interferometer designs or digital phase stabilisation. We show OCT images of a human finger knuckle joint in vivo with very high quality and deep penetration.},
       url = {http://dx.doi.org/10.1117/12.2214788},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
       type = {Conference Proceedings}
    }
    
  • Kolb, Jan Philip and Schwarz, Philipp and Klein, Thomas and Wieser, Wolfgang and Huber, Robert: Dual parametric compounding approach for speckle reduction in OCT. in Proc. SPIE, no. 9312, pp. 93123G-93123G-7, 2015
    BibTeX Link
    @inproceedings{Kolb2015,
       author = {Kolb, Jan Philip and Schwarz, Philipp and Klein, Thomas and Wieser, Wolfgang and Huber, Robert},
       title = {Dual parametric compounding approach for speckle reduction in OCT},
    Year={2015},
       volume = {9312},
       pages = {93123G-93123G-7},
       DOI = {10.1117/12.2077659},
       booktitle = {Proc. SPIE},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
       type = {Conference Proceedings}
    }
    

2014

  • Karpf, Sebastian and Eibl, Matthias and Klein, Thomas and Wieser, Wolfgang and Huber, Robert: Hyperspectral Stimulated Raman Microscopy with Fiber-based, Rapidly Wavelength Swept cw-Lasers. in CLEO: 2014, pp. 1-2, OSA, 2014
    BibTeX Link Link
    @inproceedings{HU_2014_Karpf_b,
    abstract = {A hyperspectral stimulated Raman microscopy system using rapidly wavelength swept lasers is presented. Imaging of biological samples with shot noise limited detection is demonstrated with the fiber based setup.},
    author = {Karpf, Sebastian and Eibl, Matthias and Klein, Thomas and Wieser, Wolfgang and Huber, Robert},
    booktitle = {CLEO: 2014},
    doi = {10.1364/CLEO_SI.2014.SM3P.3},
    isbn = {978-1-55752-999-2},
    keywords = {Lasers,Raman microscopy,Scattering,stimulated Raman,tunable, AG-Huber_NL},
    pages = {1--2},
    publisher = {OSA},
    title = {{Hyperspectral Stimulated Raman Microscopy with Fiber-based, Rapidly Wavelength Swept cw-Lasers}},
    url = {http://www.opticsinfobase.org/abstract.cfm?URI=CLEO\_SI-2014-SM3P.3},
    year = { 2014}
    }
  • Eibl, Matthias and Karpf, Sebastian and Wieser, Wolfgang and Klein, Thomas and Huber, Robert: Broadband, High Resolution Stimulated Raman Spectroscopy with Rapidly Wavelength Swept cw-Lasers. in CLEO: 2014, pp. ATu3P.4 1-3, OSA, 2014
    BibTeX Link Link
    @inproceedings{HU_2014_Eibl_a,
    abstract = {A fast all fiber based setup for stimulated Raman spectroscopy with a rapidly wavelength swept cw-laser is presented. It enables flexible acquisition of broadband (750 cm-1 to 3150 cm-1) spectra with high resolution (0.5 cm-1).},
    author = {Eibl, Matthias and Karpf, Sebastian and Wieser, Wolfgang and Klein, Thomas and Huber, Robert},
    booktitle = {CLEO: 2014},
    doi = {10.1364/CLEO_AT.2014.ATu3P.4},
    isbn = {978-1-55752-999-2},
    keywords = {Lasers,Raman,Scattering,Spectroscopy,stimulated Raman,tunable,AG-Huber_NL},
    pages = {ATu3P.4 1--3},
    publisher = {OSA},
    title = {{Broadband, High Resolution Stimulated Raman Spectroscopy with Rapidly Wavelength Swept cw-Lasers}},
    url = {http://www.opticsinfobase.org/abstract.cfm?URI=CLEO\_AT-2014-ATu3P.4},
    year = { 2014}
    }

2013

  • Wang, Tianshi and Wieser, Wolfgang and Springeling, Geert and Beurskens, Robert and Lancee, Charles T and Pfeiffer, Tom and van der Steen, Antonius F W and Huber, Robert and van Soest, Gijs: Ultrahigh-speed intravascular optical coherence tomography imaging at 3200 frames per second. in European Conferences on Biomedical Optics, pp. 88020O 1-2, International Society for Optics and Photonics, n,, 2013
    BibTeX Link Link
    @InProceedings{HU_2013_Wang_b,
      Title                    = {{Ultrahigh-speed intravascular optical coherence tomography imaging at 3200 frames per second}},
      Author                   = {Wang, Tianshi and Wieser, Wolfgang and Springeling, Geert and Beurskens, Robert and Lancee, Charles T and Pfeiffer, Tom and van der Steen, Antonius F W and Huber, Robert and van Soest, Gijs},
      Booktitle                = {European Conferences on Biomedical Optics},
      Year                     = {2013},
      Editor                   = {Bouma, Brett E and Leitgeb, Rainer A},
      Month                    = jun,
      Pages                    = {88020O 1--2 },
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.2032723},
    keywords = {AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.2032723}
    }
  • Eigenwillig, Christoph M and Todor, Sebastian and Wieser, Wolfgang and Biedermann, Benjamin R and Klein, Thomas and Jirauschek, Christian and Huber, Robert: Picosecond pulses from a Fourier domain mode locked (FDML) laser. in 2013 Conference on Lasers & Electro-Optics Europe & International Quantum Electronics Conference CLEO EUROPE/IQEC, pp. 1-1, IEEE, y,, 2013
    BibTeX Link Link
    @InProceedings{HU_2013_Eigenwillig_a,
      Title                    = {{Picosecond pulses from a Fourier domain mode locked (FDML) laser}},
      Author                   = {Eigenwillig, Christoph M and Todor, Sebastian and Wieser, Wolfgang and Biedermann, Benjamin R and Klein, Thomas and Jirauschek, Christian and Huber, Robert},
      Booktitle                = {2013 Conference on Lasers \& Electro-Optics Europe \& International Quantum Electronics Conference CLEO EUROPE/IQEC},
      Year                     = {2013},
      Month                    = may,
      Pages                    = {1--1},
      Publisher                = {IEEE},
      Doi                      = {10.1109/CLEOE-IQEC.2013.6801076},
      ISBN                     = {978-1-4799-0594-2},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=6801076}
    }
  • Zhang, Yaokun and Pfeiffer, Tom and Wieser, Wolfgang and Weller, Marcel and Huber, Robert and Klenzner, Thomas and Raczkowsky, Jörg and Wörn, Heinz: History compounding: a novel speckle reduction technique for OCT guided cochleostomy. in SPIE BiOS, pp. 85713H.1-3, International Society for Optics and Photonics, r,, 2013
    BibTeX Link Link
    @InProceedings{HU_2013_Zhang_a,
      Title                    = {{History compounding: a novel speckle reduction technique for OCT guided cochleostomy}},
      Author                   = {Zhang, Yaokun and Pfeiffer, Tom and Wieser, Wolfgang and Weller, Marcel and Huber, Robert and Klenzner, Thomas and Raczkowsky, J\"{o}rg and W\"{o}rn, Heinz},
      Booktitle                = {SPIE BiOS},
      Year                     = {2013},
      Editor                   = {Fujimoto, James G and Izatt, Joseph A and Tuchin, Valery V},
      Month                    = mar,
      Pages                    = {85713H.1--3},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.2006979},
    keywords = {AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.2006979}
    }
  • Karpf, Sebastian and Eibl, Matthias and Wieser, Wolfgang and Klein, Thomas and Huber, Robert: FDML Raman: New High Resolution SRS with ultra broadband spectral coverage. in 2013 Conference on Lasers and Electro-Optics - International Quantum Electronics Conference, pp. PD_A_8 1-3, Optical Society of America, Munich, 2013
    BibTeX Link Link
    @inproceedings{HU_2013_Karpf_a,
    abstract = {An all fiber based system for high speed, high resolution Raman sensing is presented. The system is based on a wavelength swept Fourier Domain Mode Locked (FDML) laser for the detection of the Raman signal.},
    address = {Munich},
    author = {Karpf, Sebastian and Eibl, Matthias and Wieser, Wolfgang and Klein, Thomas and Huber, Robert},
    booktitle = {2013 Conference on Lasers and Electro-Optics - International Quantum Electronics Conference},
    pages = {PD_A_8 1--3},
    publisher = {Optical Society of America},
    doi={10.1109/CLEOE-IQEC.2013.6801995},
    title = {{FDML Raman: New High Resolution SRS with ultra broadband spectral coverage}},
    url = {https://doi.org/10.1109/CLEOE-IQEC.2013.6801995},
    keywords = {AG-Huber_NL},
    year = { 2013}
    }
  • Karpf, Sebastian and Eibl, Matthias and Wieser, Wolfgang and Klein, Thomas and Huber, Robert: FDML Raman: High Speed, High Resolution Stimulated Raman Spectroscopy with Rapidly Wavelength Swept Lasers. in CLEO: 2013, pp. ATu3P.4 1-3, OSA, 2013
    BibTeX Link Link
    @inproceedings{HU_2013_Karpf_b,
    abstract = {An all fiber based system for high speed, high resolution Raman sensing is presented. The system is based on a wavelength swept Fourier Domain Mode Locked (FDML) laser for the detection of the Raman signal.},
    author = {Karpf, Sebastian and Eibl, Matthias and Wieser, Wolfgang and Klein, Thomas and Huber, Robert},
    booktitle = {CLEO: 2013},
    doi = {10.1364/CLEO_SI.2013.CTu2H.5},
    isbn = {978-1-55752-972-5},
    keywords = {Lasers,Raman,Scattering,Spectroscopy,fiber,stimulated Raman,AG-Huber_NL},
    pages = {ATu3P.4 1--3},
    publisher = {OSA},
    title = {{FDML Raman: High Speed, High Resolution Stimulated Raman Spectroscopy with Rapidly Wavelength Swept Lasers}},
    url = {http://www.opticsinfobase.org/abstract.cfm?URI=CLEO_SI-2013-CTu2H.5},
    year = { 2013}
    }

2012

  • Blatter, Cedric and Grajciar, Branislav and Hermann, Boris and Huber, Robert and Drexler, Wolfgang and Leitgeb, Rainer A: Simultaneous dark-bright field swept source OCT for ultrasound detection. in SPIE BiOS, pp. 82131M 1-3, International Society for Optics and Photonics, b,, 2012
    BibTeX Link Link
    @InProceedings{HU_2012_Blatter_d,
      Title                    = {{Simultaneous dark-bright field swept source OCT for ultrasound detection}},
      Author                   = {Blatter, Cedric and Grajciar, Branislav and Hermann, Boris and Huber, Robert and Drexler, Wolfgang and Leitgeb, Rainer A},
      Booktitle                = {SPIE BiOS},
      Year                     = {2012},
      Editor                   = {Izatt, Joseph A and Fujimoto, James G and Tuchin, Valery V},
      Month                    = feb,
      Pages                    = {82131M 1--3 },
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.911443},
    keywords = {AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.911443}
    }
  • Klein, Thomas and Wieser, Wolfgang and Andre, Raphael and Pfeiffer, Tom and Eigenwillig, Christoph M and Huber, Robert: Multi-MHz FDML OCT: snapshot retinal imaging at 6.7 million axial-scans per second. in SPIE BiOS, pp. 82131E 1-3, International Society for Optics and Photonics, b,, 2012
    BibTeX Link Link
    @InProceedings{HU_2012_Klein_b,
      Title                    = {{Multi-MHz FDML OCT: snapshot retinal imaging at 6.7 million axial-scans per second}},
      Author                   = {Klein, Thomas and Wieser, Wolfgang and Andre, Raphael and Pfeiffer, Tom and Eigenwillig, Christoph M and Huber, Robert},
      Booktitle                = {SPIE BiOS},
      Year                     = {2012},
      Editor                   = {Izatt, Joseph A and Fujimoto, James G and Tuchin, Valery V},
      Month                    = feb,
      Pages                    = {82131E 1--3 },
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.908798},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.908798}
    }
  • Marschall, Sebastian and Torzicky, Teresa and Klein, Thomas and Wieser, Wolfgang and Pircher, Michael and Götzinger, Erich and Zotter, Stefan and Bonesi, Marco and Biedermann, Benjamin and Pedersen, Christian and Huber, Robert and Hitzenberger, Christoph and Andersen, Peter: High-speed polarization-sensitive OCT at 1060 nm using a Fourier domain mode-locked swept source. in SPIE Photonics Europe, pp. 84271D-84271D-6, International Society for Optics and Photonics, n,, 2012
    BibTeX Link Link
    @InProceedings{HU_2012_Marschall_a,
      Title                    = {{High-speed polarization-sensitive OCT at 1060 nm using a Fourier domain mode-locked swept source}},
      Author                   = {Marschall, Sebastian and Torzicky, Teresa and Klein, Thomas and Wieser, Wolfgang and Pircher, Michael and G\"{o}tzinger, Erich and Zotter, Stefan and Bonesi, Marco and Biedermann, Benjamin and Pedersen, Christian and Huber, Robert and Hitzenberger, Christoph and Andersen, Peter},
      Booktitle                = {SPIE Photonics Europe},
      Year                     = {2012},
      Editor                   = {Popp, J\"{u}rgen and Drexler, Wolfgang and Tuchin, Valery V and Matthews, Dennis L},
      Month                    = jun,
      Pages                    = {84271D--84271D--6},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.922313},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1219832}
    }
  • Wieser, Wolfgang and Klein, Thomas and Adler, Desmond C and Trepanier, Francois and Karpf, Sebastian and Eigenwillig, Christoph and Schmitt, Joseph M and Huber, Robert: Dispersion Compensated Megahertz FDML Laser for Imaging of the Anterior Segment. in Conference on Lasers and Electro-Optics 2012, pp. JTh3J.2 1-3, OSA, Washington, D.C., 2012
    BibTeX Link Link
    @InProceedings{HU_2012_Wieser_c,
      Title                    = {{Dispersion Compensated Megahertz FDML Laser for Imaging of the Anterior Segment}},
      Author                   = {Wieser, Wolfgang and Klein, Thomas and Adler, Desmond C and Trepanier, Francois and Karpf, Sebastian and Eigenwillig, Christoph and Schmitt, Joseph M and Huber, Robert},
      Booktitle                = {Conference on Lasers and Electro-Optics 2012},
      Year                     = {2012},
    
      Address                  = {Washington, D.C.},
      Pages                    = {JTh3J.2 1--3},
      Publisher                = {OSA},
    
      Doi                      = {10.1364/CLEO_AT.2012.JTh3J.2},
      ISBN                     = {978-1-55752-943-5},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://www.opticsinfobase.org/abstract.cfm?URI=CLEO_AT-2012-JTh3J.2}
    }
  • Blatter, Cedric and Grajciar, Branislav and Huber, Robert and Leitgeb, Rainer: Deep skin structural and microcirculation imaging with extended-focus OCT. in SPIE BiOS, pp. 82070B-82070B-7, International Society for Optics and Photonics, b,, 2012
    BibTeX Link Link
    @InProceedings{HU_2012_Blatter_e,
      Title                    = {{Deep skin structural and microcirculation imaging with extended-focus OCT}},
      Author                   = {Blatter, Cedric and Grajciar, Branislav and Huber, Robert and Leitgeb, Rainer},
      Booktitle                = {SPIE BiOS},
      Year                     = {2012},
      Month                    = feb,
      Pages                    = {82070B--82070B--7},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.909830},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1310560}
    }
  • Adler, Desmond C and Wieser, Wolfgang and Trepanier, Francois and Schmitt, Joseph M and Huber, Robert A: Coherence length extension of Fourier domain mode locked lasers. in SPIE BiOS, pp. 82130O 1-3, International Society for Optics and Photonics, b,, 2012
    BibTeX Link Link
    @InProceedings{HU_2012_Adler_a,
      Title                    = {{Coherence length extension of Fourier domain mode locked lasers}},
      Author                   = {Adler, Desmond C and Wieser, Wolfgang and Trepanier, Francois and Schmitt, Joseph M and Huber, Robert A},
      Booktitle                = {SPIE BiOS},
      Year                     = {2012},
      Editor                   = {Izatt, Joseph A and Fujimoto, James G and Tuchin, Valery V},
      Month                    = feb,
      Pages                    = {82130O 1--3 },
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.908148},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.908148}
    }
  • Marschall, Sebastian and Klein, Thomas and Wieser, Wolfgang and Torzicky, Teresa and Pircher, Michael and Biedermann, Benjamin R and Pedersen, Christian and Hitzenberger, Christoph K and Huber, Robert and Andersen, Peter E: Broadband Fourier domain mode-locked laser for optical coherence tomography at 1060 nm. in SPIE BiOS, pp. 82130R 1-3, International Society for Optics and Photonics, b,, 2012
    BibTeX Link Link
    @InProceedings{HU_2012_Marschall_b,
      Title                    = {{Broadband Fourier domain mode-locked laser for optical coherence tomography at 1060 nm}},
      Author                   = {Marschall, Sebastian and Klein, Thomas and Wieser, Wolfgang and Torzicky, Teresa and Pircher, Michael and Biedermann, Benjamin R and Pedersen, Christian and Hitzenberger, Christoph K and Huber, Robert and Andersen, Peter E},
      Booktitle                = {SPIE BiOS},
      Year                     = {2012},
      Editor                   = {Izatt, Joseph A and Fujimoto, James G and Tuchin, Valery V},
      Month                    = feb,
      Pages                    = {82130R 1--3 },
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.906148},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.906148}
    }

2011

  • Hüttmann, Gereon and Rahmanzadeh, Ramtin and Rudnitzki, Florian and Endl, Elmar and Hasan, Tayyaba: Targeted molecular effects through laser-irradiated nanoabsorbers. 2011
    BibTeX Link
    @inproceedings{Hüttmann2011,
       author = {Hüttmann, Gereon and Rahmanzadeh, Ramtin and Rudnitzki, Florian and Endl, Elmar and Hasan, Tayyaba},
       title = {Targeted molecular effects through laser-irradiated nanoabsorbers},
       editor = {Newsrrom, SPIE},
       DOI = {10.1117/2.1201102.003548},
       type = {Conference Proceedings},
       year = { 2011}
    }
    
  • Blatter, Cedric and Grajciar, Branislav and Huber, Robert and Leitgeb, Rainer A: Structural and functional imaging with extended focus dark-field OCT at 1300nm. in SPIE BiOS, pp. 78891D-78891D-6, International Society for Optics and Photonics, b,, 2011
    BibTeX Link Link
    @InProceedings{HU_2011_Blatter_c,
      Title                    = {{Structural and functional imaging with extended focus dark-field OCT at 1300nm}},
      Author                   = {Blatter, Cedric and Grajciar, Branislav and Huber, Robert and Leitgeb, Rainer A},
      Booktitle                = {SPIE BiOS},
      Year                     = {2011},
      Editor                   = {Fujimoto, James G and Izatt, Joseph A and Tuchin, Valery V},
      Month                    = feb,
      Pages                    = {78891D--78891D--6},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.875594},
    keywords = {AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=732654}
    }
  • Blatter, Cedric and Grajciar, Branislav and Eigenwillig, Christoph M and Wieser, Wolfgang and Biedermann, Benjamin R and Huber, Robert and Leitgeb, Rainer A: High-speed functional OCT with self-reconstructive Bessel illumination at 1300 nm. in European Conferences on Biomedical Optics, pp. 809104-809104-6, International Society for Optics and Photonics, n,, 2011
    BibTeX Link Link
    @InProceedings{HU_2011_Blatter_b,
      Title                    = {{High-speed functional OCT with self-reconstructive Bessel illumination at 1300 nm}},
      Author                   = {Blatter, Cedric and Grajciar, Branislav and Eigenwillig, Christoph M and Wieser, Wolfgang and Biedermann, Benjamin R and Huber, Robert and Leitgeb, Rainer A},
      Booktitle                = {European Conferences on Biomedical Optics},
      Year                     = {2011},
      Editor                   = {Leitgeb, Rainer A and Bouma, Brett E},
      Month                    = jun,
      Pages                    = {809104--809104--6},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.889669},
    keywords = {AG-Huber_FDML, AG-Huber_ OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1272395}
    }
  • Klein, T and Wieser, W and Biedermann, B R and Eigenwillig, C M and Huber, R: FDML laser for megahertz retinal OCT imaging. in 2011 Conference on Lasers and Electro-Optics (CLEO), EEE, 2011
    BibTeX
    @InProceedings{HU_2011_Klein_b,
      Title                    = {{FDML laser for megahertz retinal OCT imaging}},
      Author                   = {Klein, T and Wieser, W and Biedermann, B R and Eigenwillig, C M and Huber, R},
      Booktitle                = {2011 Conference on Lasers and Electro-Optics (CLEO)},
      Year                     = {2011},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Publisher                = {IEEE}
    }

2010

  • Rahmanzadeh, Ramtin and Rai, Prakash and Gerdes, Johannes and Hasan, Tayyaba: Targeted light-inactivation of the Ki-67 protein using theranostic liposomes leads to death of proliferating cells. no. 7576, pp. 757602, SPIE, 2010
    BibTeX Link
    @inproceedings{Rahmanzadeh,
       author = {Rahmanzadeh, Ramtin and Rai, Prakash and Gerdes, Johannes and Hasan, Tayyaba},
       title = {Targeted light-inactivation of the Ki-67 protein using theranostic liposomes leads to death of proliferating cells},
       editor = {Samuel, Achilefu and Ramesh, Raghavachari},
       publisher = {SPIE},
       volume = {7576},
       pages = {757602},
    year = {2010},
    doi ={10.1117/12.843850},
    keywords = {Nanotechnology, Ovarian Cancer, Proliferative Index, Photodynamic Therapy,Antibody}
    
    }
  • Marschall, Sebastian and Klein, Thomas and Wieser, Wolfgang and Biedermann, Benjamin and Hsu, Kevin and Sumpf, Bernd and Hasler, Karl-Heinz and Erbert, Götz and Jensen, Ole B and Pedersen, Christian and Huber, Robert and Andersen, Peter E: High-power FDML laser for swept source-OCT at 1060 nm. in SPIE Photonics Europe, pp. 77150B-77150B-5, International Society for Optics and Photonics, r,, 2010
    BibTeX Link Link
    @InProceedings{HU_2010_Marschall_b,
      Title                    = {{High-power FDML laser for swept source-OCT at 1060 nm}},
      Author                   = {Marschall, Sebastian and Klein, Thomas and Wieser, Wolfgang and Biedermann, Benjamin and Hsu, Kevin and Sumpf, Bernd and Hasler, Karl-Heinz and Erbert, G\"{o}tz and Jensen, Ole B and Pedersen, Christian and Huber, Robert and Andersen, Peter E},
      Booktitle                = {SPIE Photonics Europe},
      Year                     = {2010},
      Editor                   = {Popp, J\"{u}rgen and Drexler, Wolfgang and Tuchin, Valery V and Matthews, Dennis L},
      Month                    = apr,
      Pages                    = {77150B--77150B--5},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.854238},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1345306}
    }
  • Marschall, Sebastian and Klein, Thomas and Wieser, Wolfgang and Biedermann, Benjamin and Hsu, Kevin and Sumpf, Bernd and Hasler, Karl-Heinz and Erbert, Götz and Jensen, Ole B and Pedersen, Christian and Huber, Robert and Andersen, Peter E: FDML swept source at 1060 nm using a tapered amplifier. in BiOS, pp. 75541H-75541H-5, International Society for Optics and Photonics, b,, 2010
    BibTeX Link Link
    @InProceedings{HU_2010_Marschall_c,
      Title                    = {{FDML swept source at 1060 nm using a tapered amplifier}},
      Author                   = {Marschall, Sebastian and Klein, Thomas and Wieser, Wolfgang and Biedermann, Benjamin and Hsu, Kevin and Sumpf, Bernd and Hasler, Karl-Heinz and Erbert, G\"{o}tz and Jensen, Ole B and Pedersen, Christian and Huber, Robert and Andersen, Peter E},
      Booktitle                = {BiOS},
      Year                     = {2010},
      Editor                   = {Izatt, Joseph A and Fujimoto, James G and Tuchin, Valery V},
      Month                    = feb,
      Pages                    = {75541H--75541H--5},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.842011},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1343844}
    }

2009

  • Eigenwillig, Christoph M and Biedermann, Benjamin R and Wieser, Wolfgang and Huber, Robert: Wavelength swept ASE source. in European Conferences on Biomedical Optics, pp. 73720O-73720O-6, International Society for Optics and Photonics, l,, 2009
    BibTeX Link Link
    @InProceedings{HU_2009_Eigenwillig_c,
      Title                    = {{Wavelength swept ASE source}},
      Author                   = {Eigenwillig, Christoph M and Biedermann, Benjamin R and Wieser, Wolfgang and Huber, Robert},
      Booktitle                = {European Conferences on Biomedical Optics},
      Year                     = {2009},
      Editor                   = {Andersen, Peter E and Bouma, Brett E},
      Month                    = jul,
      Pages                    = {73720O--73720O--6},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.831831},
    keywords = {AG-Huber_FDML},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=781146}
    }
  • Karnowski, Karol and Gora, Michalina and Kaluzny, Bartlomiej and Huber, Robert and Szkulmowski, Maciej and Kowalczyk, Andrzej and Wojtkowski, Maciej: Swept source OCT imaging of human anterior segment at 200 kHz. in SPIE BiOS: Biomedical Optics, pp. 716308-716308-7, International Society for Optics and Photonics, b,, 2009
    BibTeX Link Link
    @InProceedings{HU_2009_Karnowski_a,
      Title                    = {{Swept source OCT imaging of human anterior segment at 200 kHz}},
      Author                   = {Karnowski, Karol and Gora, Michalina and Kaluzny, Bartlomiej and Huber, Robert and Szkulmowski, Maciej and Kowalczyk, Andrzej and Wojtkowski, Maciej},
      Booktitle                = {SPIE BiOS: Biomedical Optics},
      Year                     = {2009},
      Editor                   = {Manns, Fabrice and S\"{o}derberg, Per G and Ho, Arthur},
      Month                    = feb,
      Pages                    = {716308--716308--7},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.808555},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1331711}
    }
  • Huber, Robert: State-of-the-art and future of ultrahigh speed OCT. in CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference, pp. 1-1, IEEE, n,, 2009
    BibTeX Link Link
    @InProceedings{HU_2009_Huber_c,
      Title                    = {{State-of-the-art and future of ultrahigh speed OCT}},
      Author                   = {Huber, Robert},
      Booktitle                = {CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference},
      Year                     = {2009},
      Month                    = jun,
      Pages                    = {1--1},
      Publisher                = {IEEE},
    
      Doi                      = {10.1109/CLEOE-EQEC.2009.5191695},
      ISBN                     = {978-1-4244-4079-5},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=5191695}
    }
  • Klein, Thomas and Wieser, Wolfgang and Biedermann, Benjamin R and Eigenwillig, Christoph M and Palte, Gesa and Huber, Robert: Raman pumped Fourier Domain Mode Locked (FDML) laser: Analysis of operation and application for optical coherence tomography (OCT). in CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference, pp. 1-1, IEEE, n,, 2009
    BibTeX Link Link
    @InProceedings{HU_2009_Klein_a,
      Title                    = {{Raman pumped Fourier Domain Mode Locked (FDML) laser: Analysis of operation and application for optical coherence tomography (OCT)}},
      Author                   = {Klein, Thomas and Wieser, Wolfgang and Biedermann, Benjamin R and Eigenwillig, Christoph M and Palte, Gesa and Huber, Robert},
      Booktitle                = {CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference},
      Year                     = {2009},
      Month                    = jun,
      Pages                    = {1--1},
      Publisher                = {IEEE},
    
      Doi                      = {10.1109/CLEOE-EQEC.2009.5194704},
      ISBN                     = {978-1-4244-4079-5},
    keywords = {AG-Huber_FDML, AG-Huber_ OCT},
      Url                      = {http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=5194704}
    }
  • Palte, Gesa and Wieser, Wolfgang and Biedermann, Benjamin R and Eigenwillig, Christoph M and Huber, Robert: Fourier domain mode locked (FDML) lasers for polarization sensitive OCT. in European Conferences on Biomedical Optics, pp. 73720M-73720M-6, International Society for Optics and Photonics, l,, 2009
    BibTeX Link Link
    @InProceedings{HU_2009_Palte_a,
      Title                    = {{Fourier domain mode locked (FDML) lasers for polarization sensitive OCT}},
      Author                   = {Palte, Gesa and Wieser, Wolfgang and Biedermann, Benjamin R and Eigenwillig, Christoph M and Huber, Robert},
      Booktitle                = {European Conferences on Biomedical Optics},
      Year                     = {2009},
      Editor                   = {Andersen, Peter E and Bouma, Brett E},
      Month                    = jul,
      Pages                    = {73720M--73720M--6},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.831835},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1339476}
    }
  • Biedermann, Benjamin R and Wieser, Wolfgang and Eigenwillig, Christoph M and Klein, Thomas and Huber, Robert: Dispersion, coherence and noise of Fourier Domain Mode Locked (FDML) lasers. in CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference, pp. 1-1, IEEE, n,, 2009
    BibTeX Link Link
    @InProceedings{HU_2009_Biedermann_b,
      Title                    = {{Dispersion, coherence and noise of Fourier Domain Mode Locked (FDML) lasers}},
      Author                   = {Biedermann, Benjamin R and Wieser, Wolfgang and Eigenwillig, Christoph M and Klein, Thomas and Huber, Robert},
      Booktitle                = {CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference},
      Year                     = {2009},
      Month                    = jun,
      Pages                    = {1--1},
      Publisher                = {IEEE},
    
      Doi                      = {10.1109/CLEOE-EQEC.2009.5192900},
      ISBN                     = {978-1-4244-4079-5},
      Pmid                     = {19506645},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=5192900}
    }
  • Huber, Robert: Advances in Fourier domain OCT. in 2009 IEEE LEOS Annual Meeting Conference Proceedings, pp. 201-202, IEEE, t,, 2009
    BibTeX Link Link
    @InProceedings{HU_2009_Huber_a,
      Title                    = {{Advances in Fourier domain OCT}},
      Author                   = {Huber, Robert},
      Booktitle                = {2009 IEEE LEOS Annual Meeting Conference Proceedings},
      Year                     = {2009},
      Month                    = oct,
      Pages                    = {201--202},
      Publisher                = {IEEE},
    
      Doi                      = {10.1109/LEOS.2009.5343314},
      ISBN                     = {978-1-4244-3680-4},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=5343314}
    }
    

2008

  • Eigenwillig, Christoph and Biedermann, Benjamin and Huber, Robert: Optical coherence tomography imaging with k-space linear Fourier Domain Mode Locked lasers. in 2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS, 2008
    BibTeX Link
    @InProceedings{HU_2008_Eigenwillig_a,
      Title                    = {{Optical coherence tomography imaging with k-space linear Fourier Domain Mode Locked lasers}},
      Author                   = {Eigenwillig, Christoph and Biedermann, Benjamin and Huber, Robert},
      Booktitle                = {2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS},
      Year                     = {2008},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
    
      Url                      = {http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=4571261&searchWithin%3Deigenwillig%26sortType%3Dasc_p_Sequence%26filter%3DAND%28p_IS_Number%3A4571172%29}
    }
  • Adler, Desmond C and Chen, Yu and Huber, Robert and Schmitt, Joseph and Connolly, James and Fujimoto, James G: In vivo endomicroscopy using three-dimensional optical coherence tomography and Fourier domain mode locked lasers. in Biomedical Optics (BiOS) 2008, pp. 684708-684708-7, International Society for Optics and Photonics, b,, 2008
    BibTeX Link Link
    @InProceedings{HU_2008_Adler_b,
      Title                    = {{In vivo endomicroscopy using three-dimensional optical coherence tomography and Fourier domain mode locked lasers}},
      Author                   = {Adler, Desmond C and Chen, Yu and Huber, Robert and Schmitt, Joseph and Connolly, James and Fujimoto, James G},
      Booktitle                = {Biomedical Optics (BiOS) 2008},
      Year                     = {2008},
      Editor                   = {Izatt, Joseph A and Fujimoto, James G and Tuchin, Valery V},
      Month                    = feb,
      Pages                    = {684708--684708--7},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.761850},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1326810}
    }
    
  • Jirauschek, Christian and Eigenwillig, Christoph and Biedermann, Benjamin and Huber, Robert: Fourier domain mode locking theory. in 2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS, 2008
    BibTeX Link
    @InProceedings{HU_2008_Jirauschek_a,
      Title                    = {{Fourier domain mode locking theory}},
      Author                   = {Jirauschek, Christian and Eigenwillig, Christoph and Biedermann, Benjamin and Huber, Robert},
      Booktitle                = {2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS},
      Year                     = {2008},
    keywords = {AG-Huber_FDML},
    
      Url                      = {http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=4571888&searchWithin%3Deigenwillig%26sortType%3Dasc_p_Sequence%26filter%3DAND%28p_IS_Number%3A4571172%29}
    }

2007

  • Adler, Desmond C and Huber, Robert and Fujimoto, James G: Phase-sensitive optical coherence tomography using buffered Fourier domain mode-locked lasers at up to 370,000 scans per second. in Biomedical Optics (BiOS) 2007, pp. 64291L-64291L-9, International Society for Optics and Photonics, b,, 2007
    BibTeX Link Link
    @InProceedings{HU_2007_Adler_d,
      Title                    = {{Phase-sensitive optical coherence tomography using buffered Fourier domain mode-locked lasers at up to 370,000 scans per second}},
      Author                   = {Adler, Desmond C and Huber, Robert and Fujimoto, James G},
      Booktitle                = {Biomedical Optics (BiOS) 2007},
      Year                     = {2007},
      Editor                   = {Fujimoto, James G and Izatt, Joseph A and Tuchin, Valery V},
      Month                    = feb,
      Pages                    = {64291L--64291L--9},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.704128},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1334093}
    }
  • Adler, Desmond C and Huber, Robert and Fujimoto, James G: Optical coherence tomography phase microscopy using buffered fourier domain mode locked (FDML) lasers at up to 370,000 lines per second. in Conference on Lasers and Electro-Optics, 2007, CLEO 2007, 2007
    BibTeX Link
    @InProceedings{HU_2007_Adler_e,
      Title                    = {{Optical coherence tomography phase microscopy using buffered fourier domain mode locked (FDML) lasers at up to 370,000 lines per second}},
      Author                   = {Adler, Desmond C and Huber, Robert and Fujimoto, James G},
      Booktitle                = {Conference on Lasers and Electro-Optics, 2007, CLEO 2007},
      Year                     = {2007},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
    
      Url                      = {http://www.opticsinfobase.org/abstract.cfm?uri=CLEO-2007-CFL1}
    }
  • Huber, Robert A and Adler, Desmond C and Srinivasan, Vivek J and Gorczynska, Iwona M and Fujimoto, James G: Fourier domain mode-locked (FDML) lasers at 1050 nm and 202,000 sweeps per second for OCT retinal imaging. in Proceedings of SPIE, no. 6429, pp. 642907-642907-7, b,, 2007
    BibTeX Link Link
    @InProceedings{HU_2007_Huber_c,
      Title                    = {{Fourier domain mode-locked (FDML) lasers at 1050 nm and 202,000 sweeps per second for OCT retinal imaging}},
      Author                   = {Huber, Robert A and Adler, Desmond C and Srinivasan, Vivek J and Gorczynska, Iwona M and Fujimoto, James G},
      Booktitle                = {Proceedings of SPIE},
      Year                     = {2007},
      Editor                   = {Fujimoto, James G and Izatt, Joseph A and Tuchin, Valery V},
      Month                    = feb,
      Pages                    = {642907--642907--7},
      Volume                   = {6429},
    
      Doi                      = {10.1117/12.704084},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1296450}
    }
  • Huber, Robert and Srinivasan, Vivek J and Adler, Desmond C and Gorczynska, I and Fujimoto, James G: Fourier Domain Mode Locking (FDML) in the non-zero dispersion regime: A laser for ultrahigh-speed retinal OCT imaging at 236kHz line rate. in Conference on Lasers and Electro-Optics, 2007, CLEO 2007, 2007
    BibTeX Link
    @InProceedings{HU_2007_Huber_b,
      Title                    = {{Fourier Domain Mode Locking (FDML) in the non-zero dispersion regime: A laser for ultrahigh-speed retinal OCT imaging at 236kHz line rate}},
      Author                   = {Huber, Robert and Srinivasan, Vivek J and Adler, Desmond C and Gorczynska, I and Fujimoto, James G},
      Booktitle                = {Conference on Lasers and Electro-Optics, 2007, CLEO 2007},
      Year                     = {2007},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
    
      Url                      = {http://www.opticsinfobase.org/abstract.cfm?uri=CLEO-2007-CThAA5}
    }

2006

  • Kranendonk, Laura A and Walewski, Joachim W and Sanders, Scott T and Huber, Robert and Fujimoto, James G: Measurements of Gas Temperature in an HCCI Engine by Use of a Fourier-Domain Mode-Locking Laser. in Laser Applilcations to Chemical, Security and Environmental Analysis, pp. TuB2 1-2, OSA, Washington, D.C., 2006
    BibTeX Link Link
    @InProceedings{HU_2006_Kranendonk_b,
      Title                    = {{Measurements of Gas Temperature in an HCCI Engine by Use of a Fourier-Domain Mode-Locking Laser}},
      Author                   = {Kranendonk, Laura A and Walewski, Joachim W and Sanders, Scott T and Huber, Robert and Fujimoto, James G},
      Booktitle                = {Laser Applilcations to Chemical, Security and Environmental Analysis},
      Year                     = {2006},
    
      Address                  = {Washington, D.C.},
      Pages                    = {TuB2 1--2 },
      Publisher                = {OSA},
    
      Doi                      = {10.1364/LACSEA.2006.TuB2},
      ISBN                     = {1-55752-799-7},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://www.opticsinfobase.org/abstract.cfm?URI=LACSEA-2006-TuB2}
    }
  • Huber, R and Taira, K and Wojtkowski, M and Fujimoto, J G: Fourier domain mode-locked lasers for swept source OCT imaging at up to 290 kHz scan rates. in Proceedings of SPIE, no. 6079, pp. 60790U-60790U-6, b,, 2006
    BibTeX Link Link
    @InProceedings{HU_2006_Huber_a,
      Title                    = {{Fourier domain mode-locked lasers for swept source OCT imaging at up to 290 kHz scan rates}},
      Author                   = {Huber, R and Taira, K and Wojtkowski, M and Fujimoto, J G},
      Booktitle                = {Proceedings of SPIE},
      Year                     = {2006},
      Editor                   = {Tuchin, Valery V. and Izatt, Joseph A. and Fujimoto, James G.},
      Month                    = feb,
      Pages                    = {60790U--60790U--6},
      Volume                   = {6079},
    
      Doi                      = {10.1117/12.648880},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1273744}
    }
  • Huber, R and Wojtkowski, M and Fujimoto, J G: Fourier domain mode locking (FDML): Three-dimensional OCT imaging at 906 frames per second. in Conference on Lasers and Electro-Optics and 2006 Quantum Electronics and Laser Science Conference, CLEO/QELS 2006, 2006
    BibTeX Link
    @InProceedings{HU_2006_Huber_d,
      Title                    = {{Fourier domain mode locking (FDML): Three-dimensional OCT imaging at 906 frames per second}},
      Author                   = {Huber, R and Wojtkowski, M and Fujimoto, J G},
      Booktitle                = {Conference on Lasers and Electro-Optics and 2006 Quantum Electronics and Laser Science Conference, CLEO/QELS 2006},
      Year                     = {2006},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
    
      Url                      = {http://www.opticsinfobase.org/abstract.cfm?uri=CLEO-2006-CMZ2}
    }

2005

  • Sharma, Vikas and Kowalevicz Jr., Andrew M and Huber, Robert and Fujimoto, James G and Minoshima, Kaoru: Three Dimensional Waveguide Splitters Fabricated in Glass Using a Femtosecond Laser Oscillator - Technical Digest (CD). in Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science and Photonic Applications Systems Technologies, pp. CThCC4, Optical Society of America, 2005
    BibTeX Link
    @InProceedings{HU_2005_Sharma_a,
      Title                    = {{Three Dimensional Waveguide Splitters Fabricated in Glass Using a Femtosecond Laser Oscillator - Technical Digest (CD)}},
      Author                   = {Sharma, Vikas and {Kowalevicz Jr.}, Andrew M and Huber, Robert and Fujimoto, James G and Minoshima, Kaoru},
      Booktitle                = {Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science and Photonic Applications Systems Technologies},
      Year                     = {2005},
      Pages                    = {CThCC4},
      Publisher                = {Optical Society of America},
    keywords = {AG-Huber},
    
      Url                      = {http://www.opticsinfobase.org/abstract.cfm?URI=CLEO-2005-CThCC4}
    }
  • Huber, Robert and Taira, Kenji and Ko, Tony H and Wojtkowski, Maciej and Srinivasan, Vivek and Hsu, Kevin and Fujimoto, James G: High-Speed, Amplified, Frequency Swept Laser at 20 kHz Sweep Rates for OCT Imaging - Technical Digest (CD). in Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science and Photonic Applications Systems Technologies, pp. JThE33, Optical Society of America, 2005
    BibTeX Link
    @InProceedings{HU_2005_Huber_b,
      Title                    = {{High-Speed, Amplified, Frequency Swept Laser at 20 kHz Sweep Rates for OCT Imaging - Technical Digest (CD)}},
      Author                   = {Huber, Robert and Taira, Kenji and Ko, Tony H and Wojtkowski, Maciej and Srinivasan, Vivek and Hsu, Kevin and Fujimoto, James G},
      Booktitle                = {Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science and Photonic Applications Systems Technologies},
      Year                     = {2005},
      Pages                    = {JThE33},
      Publisher                = {Optical Society of America},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
    
      Url                      = {http://www.opticsinfobase.org/abstract.cfm?URI=QELS-2005-JThE33}
    }
  • Huber, Robert and Taira, Kenji and Wojtkowski, Maciej and Ko, Tony H and Fujimoto, James G and Hsu, Kevin: High-speed frequency swept light source for Fourier domain OCT at 20 kHz A-scan rate. in Biomedical Optics 2005, pp. 96-100, International Society for Optics and Photonics, r,, 2005
    BibTeX Link Link
    @InProceedings{HU_2005_Huber_f,
      Title                    = {{High-speed frequency swept light source for Fourier domain OCT at 20 kHz A-scan rate}},
      Author                   = {Huber, Robert and Taira, Kenji and Wojtkowski, Maciej and Ko, Tony H and Fujimoto, James G and Hsu, Kevin},
      Booktitle                = {Biomedical Optics 2005},
      Year                     = {2005},
      Editor                   = {Tuchin, Valery V and Izatt, Joseph A and Fujimoto, James G},
      Month                    = apr,
      Pages                    = {96--100},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.592552},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1323562}
    }
  • Huber, Robert A and Taira, Kenji and Fujimoto, James G: Fourier Domain Mode Locking: Overcoming limitations of frequency swept light sources and pulsed lasers. in Conference on Lasers and Electro-Optics Europe/ European Quantum Electronics Conference (CLEO/Europe - EQEC 2005), 2005
    BibTeX
    @InProceedings{HU_2005_Huber_a,
      Title                    = {{Fourier Domain Mode Locking: Overcoming limitations of frequency swept light sources and pulsed lasers}},
      Author                   = {Huber, Robert A and Taira, Kenji and Fujimoto, James G},
      Booktitle                = {Conference on Lasers and Electro-Optics Europe/ European Quantum Electronics Conference (CLEO/Europe - EQEC 2005)},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
      Year                     = { 2005}
    }
  • Huber, R and Taira, K and Wojtkowski, M and Fujimoto, J G: Fourier domain mode locked lasers for OCT imaging at up to 290 kHz sweep rates. in European Conference on Biomedical Optics 2005, pp. 58611B-58611B-6, International Society for Optics and Photonics, n,, 2005
    BibTeX Link Link
    @InProceedings{HU_2005_Huber_g,
      Title                    = {{Fourier domain mode locked lasers for OCT imaging at up to 290 kHz sweep rates}},
      Author                   = {Huber, R and Taira, K and Wojtkowski, M and Fujimoto, J G},
      Booktitle                = {European Conference on Biomedical Optics 2005},
      Year                     = {2005},
      Editor                   = {Drexler, Wolfgang},
      Month                    = jun,
      Pages                    = {58611B--58611B--6},
      Publisher                = {International Society for Optics and Photonics},
    keywords = {AG-Huber_FDML, AG-Huber_OCT},
    
      Doi                      = {10.1117/12.641732},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=867251}
    }

2003

  • Huber, Robert and Moser, Jacques E and Gratzel, Michael and Wachtveitl, Josef L: Beyond vibrationally mediated electron transfer: interfacial charge injection on a sub-10-fs time scale. in Optical Science and Technology, SPIE`s 48th Annual Meeting, pp. 121-131, International Society for Optics and Photonics, c,, 2003
    BibTeX Link Link
    @InProceedings{HU_2003_Huber_b,
      Title                    = {{Beyond vibrationally mediated electron transfer: interfacial charge injection on a sub-10-fs time scale}},
      Author                   = {Huber, Robert and Moser, Jacques E and Gratzel, Michael and Wachtveitl, Josef L},
      Booktitle                = {Optical Science and Technology, SPIE's 48th Annual Meeting},
      Year                     = {2003},
      Editor                   = {Lian, Tianquan and Dai, Hai-Lung},
      Month                    = dec,
      Pages                    = {121--131},
      Publisher                = {International Society for Optics and Photonics},
    
      Doi                      = {10.1117/12.506722},
    keywords = {AG-Huber},
      Url                      = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=828500}
    }

2002

  • Wachtveitl, Josef and Huber, Robert and Moser, Jacques E and Gratzel, Michael: Photoinduced electron transfer in dye/semiconductor systems on a sub-10-fs time scale - 2002 OSA Technical Digest Series. in The Thirteenth International Conference on Ultrafast Phenomena, pp. ThC5, Optical Society of America, 2002
    BibTeX Link
    @InProceedings{HU_2002_Wachtveitl_a,
      Title                    = {{Photoinduced electron transfer in dye/semiconductor systems on a sub-10-fs time scale - 2002 OSA Technical Digest Series}},
      Author                   = {Wachtveitl, Josef and Huber, Robert and Moser, Jacques E and Gratzel, Michael},
      Booktitle                = {The Thirteenth International Conference on Ultrafast Phenomena},
      Year                     = {2002},
      Pages                    = {ThC5},
      Publisher                = {Optical Society of America},
    keywords = {AG-Huber},
    
      Url                      = {http://www.opticsinfobase.org/abstract.cfm?URI=UP-2002-ThC5}
    }
  • Huber, Robert and Moser, Jacques E and Grätzel, Michael and Wachtveitl, Josef: Observation of photoinduced electron transfer in dye/semiconductor colloidal systems with different coupling strengths. in Chemical Physics, no. 285, pp. 39-45, c,, 2002
    BibTeX Link Link
    @InProceedings{HU_2002_Huber_b,
      Title                    = {{Observation of photoinduced electron transfer in dye/semiconductor colloidal systems with different coupling strengths}},
      Author                   = {Huber, Robert and Moser, Jacques E and Gr\"{a}tzel, Michael and Wachtveitl, Josef},
      Booktitle                = {Chemical Physics},
      Year                     = {2002},
      Month                    = dec,
      Number                   = {1},
      Pages                    = {39--45},
      Volume                   = {285},
    keywords = {AG-Huber},
    
      Doi                      = {10.1016/S0301-0104(02)00687-0},
      ISSN                     = {03010104},
      Url                      = {http://linkinghub.elsevier.com/retrieve/pii/S0301010402006870}
    }

2000

  • Huber, Robert and Spörlein, Sebastian and Moser, Jacques E and Grätzel, Michael and Wachtveitl, Josef: Surface States Control Ultrafast Electron Injection in Dye/Semiconductor Colloidal Systems. in Ultrafast Phenomena XII - Proceedings of the 12th International Conference, pp. 456-458, Springer-Verlag, Berlin - Heidelberg /Germany) - New York, Charleston, SC (USA), 2000
    BibTeX Link Link
    @InProceedings{HU_2000_Huber_b,
      Title                    = {{Surface States Control Ultrafast Electron Injection in Dye/Semiconductor Colloidal Systems}},
      Author                   = {Huber, Robert and Sp\"{o}rlein, Sebastian and Moser, Jacques E and Gr\"{a}tzel, Michael and Wachtveitl, Josef},
      Booktitle                = {Ultrafast Phenomena XII - Proceedings of the 12th International Conference},
      Year                     = {2000},
      Pages                    = {456--458},
      Publisher                = {Springer-Verlag, Berlin - Heidelberg /Germany) - New York, Charleston, SC (USA)},
      Series                   = {Springer Series in Chemical Physics},
    keywords = {AG-Huber},
    
      Doi                      = {10.1007/978-3-642-56546-5\_133},
      Url                      = {http://link.springer.com/chapter/10.1007\%2F978-3-642-56546-5\_133}
    }

1998

  • Huber, R and Koch, M and Perner, M and Spirkl, W and Feldmann, J: Time-resolved thermal expansion of an STM tip after ultrafast optical excitation. in Technical Digest. Summaries of Papers Presented at the Conference on Lasers and Electro-Optics. Conference Edition. 1998 Technical Digest Series, Vol.6 (IEEE Cat. No.98CH36178), pp. 526-527, Opt. Soc. America, 1998
    BibTeX Link Link
    @InProceedings{HU_1998_Huber_a,
      Title                    = {{Time-resolved thermal expansion of an STM tip after ultrafast optical excitation}},
      Author                   = {Huber, R and Koch, M and Perner, M and Spirkl, W and Feldmann, J},
      Booktitle                = {Technical Digest. Summaries of Papers Presented at the Conference on Lasers and Electro-Optics. Conference Edition. 1998 Technical Digest Series, Vol.6 (IEEE Cat. No.98CH36178)},
      Year                     = {1998},
      Pages                    = {526--527},
      Publisher                = {Opt. Soc. America},
    keywords = {AG-Huber},
    
      Doi                      = {10.1109/CLEO.1998.676586},
      ISBN                     = {1-55752-339-0},
      Url                      = {http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=676586}
    }

018

  • Uzunbajakava, N E; Varghese, B; Botchkareva, N V; Verhagen, R and Vogel, A: Highlighting the nuances behind interaction of picosecond pulses with human skin: Relating distinct laser-tissue interactions to their potential in cutaneous interventions. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE, no. 0492 ,, 018
    BibTeX Link
    @inproceedings{Vogel2018,
       author = {Uzunbajakava, N E; Varghese, B; Botchkareva, N V; Verhagen, R and Vogel, A},
       title = {Highlighting the nuances behind interaction of picosecond pulses with human skin: Relating distinct laser-tissue interactions to their potential in cutaneous interventions},
       booktitle = {Progress in Biomedical Optics and Imaging - Proceedings of SPIE},
       volume = {10492} ,
       DOI = {10.1117/12.2307804}
       year = {2018}
    date = {2018-20-02},
       type = {Conference Proceedings}
    }

  • Gabel, V. P. and Birngruber, R. and Hillenkamp, F.: Visible and near infrared light absorption in pigment epithelium and choroid.. in XXIII Concilium Ophthalmologicum, pp. 658-662,
    BibTeX
    @inproceedings{Gabel1978,
       author = {Gabel, V. P. and Birngruber, R. and Hillenkamp, F.},
       title = {Visible and near infrared light absorption in pigment epithelium and choroid.},
       booktitle = {XXIII Concilium Ophthalmologicum},
       editor = {Shimizu, Koichi},
       series = {International Congress Series No. 450},
       pages = {658-662},
    
    }
    
  • Hillmann, Dierck and Huttmann, Gereon and Koch, Peter: Using nonequispaced fast Fourier transformation to process optical coherence tomography signals. no. 7372, pp. 73720R, SPIE,
    BibTeX
    @inproceedings{Hillmann,
       author = {Hillmann, Dierck and Huttmann, Gereon and Koch, Peter},
       title = {Using nonequispaced fast Fourier transformation to process optical coherence tomography signals},
       editor = {Peter, E. Andersen and Brett, E. Bouma},
       publisher = {SPIE},
       volume = {7372},
       pages = {73720R},
    
    }
  • Bonin, Tim and Hagen-Eggert, Martin and Franke, Gesa and Koch, Peter and Huttmann, Gereon: Ultra highspeed in-vivo Fourier domain full-field OCT of the human retina. no. 7889, pp. 788906, SPIE,
    BibTeX
    @inproceedings{Bonin2011,
       author = {Bonin, Tim and Hagen-Eggert, Martin and Franke, Gesa and Koch, Peter and Huttmann, Gereon},
       title = {Ultra highspeed in-vivo Fourier domain full-field OCT of the human retina},
       editor = {James, G. Fujimoto and Joseph, A. Izatt and Valery, V. Tuchin},
       publisher = {SPIE},
       volume = {7889},
       pages = {788906},
    
    }
  • Bliedtner, Katharina and Seifert, Eric and Stockmann, Leoni and Effe, Lisa and Brinkmann, Ralf: Towards real time speckle controlled retinal photocoagulation. no. 9693, pp. 96931A-96931A-6,
    BibTeX Link
    @inproceedings{Bliedtner2016,
       author = {Bliedtner, Katharina and Seifert, Eric and Stockmann, Leoni and Effe, Lisa and Brinkmann, Ralf},
       title = {Towards real time speckle controlled retinal photocoagulation},
       volume = {9693},
       pages = {96931A-96931A-6},
       note = {10.1117/12.2212703},
       abstract = {Photocoagulation is a laser treatment widely used for the therapy of several retinal diseases. Intra- and inter-individual variations of the ocular transmission, light scattering and the retinal absorption makes it impossible to achieve a uniform effective exposure and hence a uniform damage throughout the therapy. A real-time monitoring and control of the induced damage is highly requested. Here, an approach to realize a real time optical feedback using dynamic speckle analysis is presented. A 532 nm continuous wave Nd:YAG laser is used for coagulation. During coagulation, speckle dynamics are monitored by a coherent object illumination using a 633nm HeNe laser and analyzed by a CMOS camera with a frame rate up to 1 kHz. It is obvious that a control system needs to determine whether the desired damage is achieved to shut down the system in a fraction of the exposure time. Here we use a fast and simple adaption of the generalized difference algorithm to analyze the speckle movements. This algorithm runs on a FPGA and is able to calculate a feedback value which is correlated to the thermal and coagulation induced tissue motion and thus the achieved damage. For different spot sizes (50-200 μm) and different exposure times (50-500 ms) the algorithm shows the ability to discriminate between different categories of retinal pigment epithelial damage ex-vivo in enucleated porcine eyes. Furthermore in-vivo experiments in rabbits show the ability of the system to determine tissue changes in living tissue during coagulation.},
       url = {http://dx.doi.org/10.1117/12.2212703},
       type = {Conference Proceedings}
    }
    
  • Vogel, Alfred and Busch, Stefan and Asiyo-Vogel, Mary: Time-resolved measurements of shock-wave emission and cavitation-bubble generation in intraocular laser surgery with ps- and ns-pulses and related tissue effects. no. 1877, pp. 312-322,
    BibTeX Link
    @inproceedings{Vogel1993,
       author = {Vogel, Alfred and Busch, Stefan and Asiyo-Vogel, Mary},
       title = {Time-resolved measurements of shock-wave emission and cavitation-bubble generation in intraocular laser surgery with ps- and ns-pulses and related tissue effects},
       volume = {1877},
       pages = {312-322},
       note = {10.1117/12.147544},
       abstract = {Intraocular microsurgery relies on plasma generation with subsequent shock wave emission and cavitation bubble formation. To assess the potentials of photodisruption with picosecond pulses in comparison to the clinical techniques presently used, the shock wave characteristics and the bubble expension after optical breakdown with picosecond and nanosecond laser pulses were investigated by time resolved photography and acoustic measurements. Nd:YAG laser pulses with a wavelength of 1064 nm and a duration of 30 ps and 6 ns were focused into a water-filled glass cuvette. Their breakdown thresholds were 15 (mu) J and 200 (mu) J, respectively. Frequency doubled light from the same laser pulses was optically delayed between 2 ns and 136 ns and used as illumination source for photography. Since the individual events were well reproducible, the shock wave position and bubble wall position could be determined as a function of time. From the slope of these r(t) curves, the shock wave and bubble wall velocities were determined. The shock wave pressure p(r) was calculated from the shock velocity using the `jump conditions' of the shock front and the equation of state of water. The collateral effects of intraocular microsurgery can thus be considerably reduced by using ps-pulses, and with series of ps-pulses a `laser scalpel' may be realized which offers new applications of photodisruption.},
       url = {http://dx.doi.org/10.1117/12.147544},
       type = {Conference Proceedings}
    }
    
  • Schlott, Kerstin and Langejürgen, Jens and Bever, Marco and Koinzer, Stefan and Birngruber, Reginald and Brinkmann, Ralf: Time resolved detection of tissue denaturation during retinal photocoagulation. pp. 73730E-73730E,
    BibTeX Link
    @inproceedings{Schlott2009,
       author = {Schlott, Kerstin and Langejürgen, Jens and Bever, Marco and Koinzer, Stefan and Birngruber, Reginald and Brinkmann, Ralf},
       title = {Time resolved detection of tissue denaturation during retinal photocoagulation},
       editor = {7373, Proc. SPIE},
       pages = {73730E-73730E},
       note = {10.1117/12.831877},
       abstract = {The retinal photocoagulation is an established treatment method for different retinal diseases. The extent of the thermal coagulations depends strongly on the generated temperature increase. Until now the dosage is based on a pool of experience of the treating physicians as well as the appearance of the whitish lesions on the retina. The temperature course during photocoagulation can be measured in real-time by optoacoustics. A frequency-doubled Q-switched Nd:YLF laser (523nm, 75 ns) is used for optoacoustic excitation and a continuous-wave Nd:YAG laser (532nm) with adjustable irradiation time and power for heating of the fundus tissue. The onset of coagulation is determined by a photodiode that is placed directly behind enucleated porcine eyes, which served as a model. The onset of coagulation is observed clearly when scattering sets in. The required power for coagulation increases exponentially with decreasing irradiation time. The first results on rabbit eyes in vivo indicate that the onset of coagulation defined by just barely visibile lesions at a slit lamp sets in at an ED50 threshold temperature of 63°C for an irradiation time of 400 ms. In conclusion, optoacoustics can be used to determine temperatures during retinal laser treatments in real-time. This allows evaluating the time-temperature-dependence of retinal coagulation in vivo.},
       keywords = {AutoPhoN},
       url = {http://dx.doi.org/10.1117/12.831877},
       type = {Conference Proceedings}
    }
    
  • Hüttmann, G. and Churio, S. and Braslavsky, S.E. and Birngruber, R.: The Possibility of Measuring Thermal Protein Denaturation by an Optoacoustic Method.. in Proc. SPIE, no. 2077, pp. 202-212,
    BibTeX
    @inproceedings{Hüttmann,
       author = {Hüttmann, G. and Churio, S. and Braslavsky, S.E. and Birngruber, R.},
       title = {The Possibility of Measuring Thermal Protein Denaturation by an Optoacoustic Method.},
       booktitle = {Proc. SPIE},
       volume = {2077},
       pages = {202-212},
    
    }
    
  • Vogel, A and Scammon, R.J. and Godwin, R.P.: Tensile stress generation by optical breakdown in tissue: experimental investigations and numerical simulations. in Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical, no. 3601, pp. 191-206, Proc. SPIE,
    BibTeX
    @inproceedings{Vogel,
       author = {Vogel, A and Scammon, R.J. and Godwin, R.P.},
       title = {Tensile stress generation by optical breakdown in tissue: experimental investigations and numerical simulations},
       booktitle = {Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical},
       publisher = {Proc. SPIE},
       volume = {3601},
       pages = {191-206},
    
    }
    
  • Bliedtner, Kathrin and Seifert, Eric and Brinkmann, Ralf: Temperature induced tissue deformation monitored by dynamic speckle interferometry. in Studierendentagung, Universität zu Lübeck,
    BibTeX
    @inproceedings{Bliedtner2013,
       author = {Bliedtner, Kathrin and Seifert, Eric and Brinkmann, Ralf},
       title = {Temperature induced tissue deformation monitored
    by dynamic speckle interferometry},
       booktitle = {Studierendentagung},
       publisher = {Universität zu Lübeck},
       type = {Conference Proceedings}
    }
    
  • Fink, Peer K and Hillmann, Dierck and Franke, Gesa L and Ramm, Dirk and Koch, P and Hüttmann, Gereon: Stray light rejection by structured illumination. in Studierendentagung, Universität zu Lübeck,
    BibTeX
    @inproceedings{Peer2013,
       author = {Fink, Peer K and Hillmann, Dierck and Franke, Gesa L and Ramm, Dirk and Koch, P and Hüttmann, Gereon},
       title = {Stray light rejection by structured illumination},
       booktitle = {Studierendentagung},
       publisher = {Universität zu Lübeck},
       type = {Conference Proceedings}
    }
    
  • Buj, C and Horstmann, J and Münter, M and Brinkmann, R: Speckle-based holographic detection for non-contact Photoacoustic Tomography. in 48th annual conference of the German Society for Biomedical Engineering, no. 59, pp. 844-847,
    BibTeX
    @inproceedings{Buj14,
       author = {Buj, C and Horstmann, J and Münter, M and Brinkmann, R},
       title = {Speckle-based holographic detection for non-contact Photoacoustic Tomography},
       booktitle = {48th annual conference of the German Society for Biomedical Engineering},
       volume = {59},
       pages = {844-847},
       type = {Conference Proceedings}
    }
    
    
  • Klawitter, Dominico and Hillmann, Dierck and Pieper, M and Steven, Philipp and Wenzel, J and Hüttmann, Gereon: Speckle variance optical coherence tomography for imaging microcirculation. in Studierendentagung, Universität zu Lübeck,
    BibTeX
    @inproceedings{Klawitter2013,
       author = {Klawitter, Dominico and Hillmann, Dierck and Pieper, M and Steven, Philipp and Wenzel, J and Hüttmann, Gereon},
       title = {Speckle variance optical coherence tomography for
    imaging microcirculation},
       booktitle = {Studierendentagung},
       publisher = {Universität zu Lübeck},
       type = {Conference Proceedings}
    }
    
  • Framme, C. and Alt, C. and Schnell, S. and Brinkmann, R. and Lin, C. P.: Selektive RPE-Behandlung (SRT) durch Laserscanning eines CW- Lasers. in 102nd Congress Deutsche Ophthalmologische Gesellschaft,
    BibTeX
    @inproceedings{Framme,
       author = {Framme, C. and Alt, C. and Schnell, S. and Brinkmann, R. and Lin, C. P.},
       title = {Selektive RPE-Behandlung (SRT) durch Laserscanning eines CW- Lasers},
       booktitle = {102nd Congress Deutsche Ophthalmologische Gesellschaft},
    
    }
    
  • Diddens, H.: Role of multidrug resistance in photodynamic therapy. no. 1645, pp. 115-123, SPIE,
    BibTeX
    @inproceedings{Diddens,
       author = {Diddens, H.},
       title = {Role of multidrug resistance in photodynamic therapy},
       editor = {Thomas, J. Dougherty},
       publisher = {SPIE},
       volume = {1645},
       pages = {115-123},
    
    }
    
  • Bliedtner, K; Seifert, E; Brinkmann, R and E D Amelink A: Real Time Speckle Monitoring to Control Retinal Photocoagulation. in Proc. SPIE 10413, pp. 1041308-1-7,
    BibTeX Link
    @inproceedings{Bliedtner2017,
       author = {Bliedtner, K; Seifert, E; Brinkmann, R and  Amelink A},
       title = {Real Time Speckle Monitoring to Control Retinal Photocoagulation},
       booktitle = {Proc. SPIE} {10413},
       
       pages = {1041308-1-7},
      
    url = { https://doi.org/10.1117/12.2287815}
  • Ansari, Rehman and Aherrahrou, Redouane and Aherrahrou, Zouhair and Erdmann, Jeanette and Huttmann, Gereon and Schweikard, Achim: Quantitative analysis of cardiomyocyte dynamics with optical coherence phase microscopy. no. 8213, pp. 821338, SPIE,
    BibTeX
    @inproceedings{Ansari2012,
       author = {Ansari, Rehman and Aherrahrou, Redouane and Aherrahrou, Zouhair and Erdmann, Jeanette and Huttmann, Gereon and Schweikard, Achim},
       title = {Quantitative analysis of cardiomyocyte dynamics with optical coherence phase microscopy},
       editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
       publisher = {SPIE},
       volume = {8213},
       pages = {821338},
    
    }
  • Hüttmann, G. and Hendrich, C. and Birngruber, R. and Lehnert, C. and Seara, J. and Siebert, W. E. and Diddens, H.: Protoporphyrin IX distribution after intra-articular and systemic application of 5-aminolevulinic acid in healthy and arthritic joints . Mechanisms and Techniques in Photodynamic Therapy V,. in Proc. SPIE, no. 2675, pp. 238-242,
    BibTeX
    @inproceedings{Hüttmann,
       author = {Hüttmann, G. and Hendrich, C. and Birngruber, R. and Lehnert, C. and Seara, J. and Siebert, W. E. and Diddens, H.},
       title = {Protoporphyrin IX distribution after intra-articular and systemic application of 5-aminolevulinic acid in healthy and arthritic joints . 
    Mechanisms and Techniques in Photodynamic Therapy V,},
       booktitle = {Proc. SPIE},
       volume = {2675},
       pages = {238-242},
    
    }
    
  • Baade, A and Schwarzer, W and Koinzer, S and Schlott, K and Birngruber, R and Brinkman, R: Power-controlled temperature guided retinal photocoagulation. in Photonic West BIOS,
    BibTeX
    @inproceedings{Baade2015,
       author = {Baade, A and Schwarzer, W and Koinzer, S and Schlott, K and Birngruber, R and Brinkman, R},
       title = {Power-controlled temperature guided retinal photocoagulation },
       booktitle = {Photonic West BIOS},
       type = {Conference Proceedings}
    }
    
  • Fleischhauer, Felix and Schulz-Hildebrandt, Hinnerk and Bonin, Tim and Hüttmann, Gereon: Polarization-sensitive optical coherence tomography on different tissues samples for tumor discrimination. in Studierendentagung, Universität zu Lübeck,
    BibTeX
    @inproceedings{Fleischhauer2013,
       author = {Fleischhauer, Felix and Schulz-Hildebrandt, Hinnerk and Bonin, Tim and Hüttmann, Gereon},
       title = {Polarization-sensitive optical coherence tomography on different tissues samples for tumor discrimination},
       booktitle = {Studierendentagung},
       publisher = {Universität zu Lübeck},
       type = {Conference Proceedings}
    }
    
  • Gabel, V. P. and Birngruber, R.: Physical and Medical Aspects of Laser Safety. in Laser 79, Opto-Electronics Conference proceedings, pp. 6555-6591, IPC Science and Technology Press Ltd.,
    BibTeX
    @inproceedings{Gabel1979,
       author = {Gabel, V. P. and Birngruber, R.},
       title = {Physical and Medical Aspects of Laser Safety},
       booktitle = {Laser 79, Opto-Electronics Conference proceedings},
       editor = {Waidlich, W.},
       publisher = {IPC Science and Technology Press Ltd.},
       pages = {6555-6591},
    
    }
    
  • Horstmann, Jens and Baade, Alexander and Brinkmann, Ralf: Photoacoustic blood vessel detection during surgical laser interventions. no. 8092, pp. 80920Z-80920Z-6, SPIE ECBO,
    BibTeX Link
    @inproceedings{Horstmann2011,
       author = {Horstmann, Jens and Baade, Alexander and Brinkmann, Ralf},
       title = {Photoacoustic blood vessel detection during surgical laser interventions},
       publisher = {SPIE ECBO},
       volume = {8092},
       pages = {80920Z-80920Z-6},
       note = {10.1117/12.889635},
       abstract = {This paper presents a discussion about the potential of photoacoustics with regard to its application in surgical assistance during minimally invasive, laser assisted interventions. Aim of the work is the detection of obscured large blood vessels in order to prevent unintentional dissection. Based on spectroscopic investigations of the target tissue (liver), a wavelength for the photoacoustic excitation laser was chosen with respect to a high absorption contrast between the vessel and the surrounding liver tissue. An experimental setup featuring a simple liver model is created. Preliminary results show, that vessels with a diameter of 2 mm can be detected up to a distance of 1 mm from the treatment fibre. It is shown, that detection of acoustic waves induced inside liver is feasible over distances higher than 10 cm.},
       url = {http://dx.doi.org/10.1117/12.889635},
       type = {Conference Proceedings}
    }
    
  • Theisen-Kunde, D and Tedsen, S and Danicke, V and Herrmann, K and Brinkmann, R: Partial kidney resection by use of a 1,94 µm thulium fiber laser. in Proc ECBO, no. 6632, SPIE,
    BibTeX
    @inproceedings{Theisen-Kunde2007,
       author = {Theisen-Kunde, D and Tedsen, S and Danicke, V and Herrmann, K and Brinkmann, R},
       title = {Partial kidney resection by use of a 1,94 µm thulium fiber laser},
       booktitle = {Proc ECBO},
       series = {Therapeutic Laser Applications and Laser-Tissue Interactions},
       publisher = {SPIE},
       volume = {6632},
       type = {Conference Proceedings}
    }
    
  • Kandulla, J and Elsner, H and Hilmes, M and Hartert, C and Brinkmann, R: Optoacoustic temperature determination at the fundus of the eye during Transpupillary Thermotherapy. in Proc SPIE, no. 5688, pp. 208-214,
    BibTeX
    @inproceedings{Kandulla2005,
       author = {Kandulla, J and Elsner, H and Hilmes, M and Hartert, C and Brinkmann, R},
       title = {Optoacoustic temperature determination at the fundus of the eye during Transpupillary Thermotherapy},
       booktitle = {Proc SPIE},
       volume = {5688},
       pages = {208-214},
       keywords = {AutoPhoN},
       type = {Conference Proceedings}
    }
    
  • Schlott, Kerstin and Koinzer, Stefan and Ptaszynski, Lars and Luft, Susanne and Baade, Alex and Bever, Marco and Roider, Johann and Birngruber, Reginald and Brinkmann, Ralf: Optoacoustic temperature determination and automatic coagulation control in rabbits. in Ophthalmic Technologies XXI, no. 7885, Proc. SPIE,
    BibTeX Link
    @inproceedings{Schlott2011,
       author = {Schlott, Kerstin and Koinzer, Stefan and Ptaszynski, Lars and Luft, Susanne and Baade, Alex and Bever, Marco and Roider, Johann and Birngruber, Reginald and Brinkmann, Ralf},
       title = {Optoacoustic temperature determination and automatic coagulation control in rabbits},
       booktitle = {Ophthalmic Technologies XXI },
       editor = {Ho, Fabrice Manns; Per G. Söderberg; Arthur},
       publisher = {Proc. SPIE},
       volume = {7885},
       note = {10.1117/12.875104},
       abstract = {Retinal laser photocoagulation is an established treatment method for many retinal diseases like macula edema or diabetic retinopathy. The selection of the laser parameters is so far based on post treatment evaluation of the lesion size and strength. Due to local pigment variations in the fundus and individual transmission the same laser parameters often lead to an overtreatment. Optoacoustic allows a non invasive monitoring of the retinal temperature increase during retinal laser irradiation by measuring the temperature dependent pressure amplitudes, which are induced by short probe laser pulses. A 75 ns/ 523 nm Nd:YLF was used as a probe laser at a repetition rate of 1 kHz, and a cw / 532 nm treatment laser for heating. A contact lens was modified with a ring-shaped ultrasonic transducer to detect the pressure waves at the cornea. Temperatures were collected for irradiations leading to soft or invisible lesions. Based on this data the threshold for denaturation was found. By analyzing the initial temperature increase, the further temperature development during irradiation could be predicted. An algorithm was found to calculate the irradiation time, which is needed for a soft lesion formation, from the temperature curve. By this it was possible to provide a real-time dosimetry by automatically switching off the treatment laser after the calculated irradiation time. Automatically controlled coagulations appear softer and more uniformly.},
       keywords = {AutoPhoN},
       url = {http://dx.doi.org/10.1117/12.875104},
       type = {Conference Proceedings}
    }
    
  • Schlott, Kerstin and Stalljohann, Jens and Weber, Benjamin and Kandulla, Jochen and Herrmann, Katharina and Birngruber, Reginald and Brinkmann, Ralf: Optoacoustic online temperature determination during retinal laser photocoagulation. no. 6632, pp. 66321B-66321B-8,
    BibTeX Link
    @inproceedings{Schlott2007,
       author = {Schlott, Kerstin and Stalljohann, Jens and Weber, Benjamin and Kandulla, Jochen and Herrmann, Katharina and Birngruber, Reginald and Brinkmann, Ralf},
       title = {Optoacoustic online temperature determination during retinal laser photocoagulation},
       volume = {6632},
       pages = {66321B-66321B-8},
       note = {10.1117/12.728291},
       abstract = {Retinal photocoagulation is an established treatment of different retinal diseases. The treatment relies on a short, local heating of the tissue which induces a denaturation. The resulting scar formation may for example prevent the further detachment of the retina. The extent of the coagulation is besides other parameters mostly dependent on the induced temperature increase. However, until today a temperature based dosimetry for photocoagulation does not exist. The dosage is rather based on the experience of the treating physicians to achieve visible whitish lesions on the retina. In this work a technique is presented, which allows an online temperature monitoring during photocoagulation. If an absorbing material is irradiated with short laser pulses, a thermoelastic expansion of the absorber induces an acoustic wave. Its amplitude is dependent on the temperature of the absorber. For analyzing the applicability of the optoacoustic temperature determination for dosimetry, measurements were performed on enucleated porcine eye globes. The pressure transients are detected by an ultrasonic transducer, which is embedded in an ophthalmologic contact lens. As long as no strong lesions occur, the determined temperatures are almost proportional to the power of the treatment laser. Using a spot diameter of 200 μm and different laser powers, the temperature rise at the end of the 400 ms irradiation was found to be approximately 0.16 °C/mW. The onset of the denaturation was observed around 50°C. The far aim of this project is an automatic regulation of the treatment laser onto a desired temperature course.},
       url = {http://dx.doi.org/10.1117/12.728291},
       type = {Conference Proceedings}
    }
    
  • Schuele, Georg and Joachimmeyer, Elke and Framme, Carsten and Roider, Johann and Birngruber, Reginald and Brinkmann, Ralf: Optoacoustic detection of selective RPE cell damage during μs-laser irradiation. no. 4433, pp. 92-96,
    BibTeX Link
    @inproceedings{Schuele2001,
       author = {Schuele, Georg and Joachimmeyer, Elke and Framme, Carsten and Roider, Johann and Birngruber, Reginald and Brinkmann, Ralf},
       title = {Optoacoustic detection of selective RPE cell damage during μs-laser irradiation},
       volume = {4433},
       pages = {92-96},
       note = {10.1117/12.446507},
       abstract = {Objective: The selective damage of the retinal pigment epithelium (RPE) with repetitive microsecond(s) laser pulses is a new technique for the treatment of several retinal diseases. RPE can selectively be damaged by simultaneously sparing off the adjacent photoreceptor tissue. Objective of this study is to investigate whether optoacoustic (OA) transients occurring during irradiation might be used to control the invisible treatment effect. Setup: A train of frequency doubled Nd:YLF laser pulses (527 nm, 1.7microsecond(s) pulse length, 500Hz rep. rate) were applied via a laser slit lamp on porcine RPE samples. The acoustic transients were recorded with a broadband transducer. Results: At low radiant exposures (<100 mJ/cm2) we found a bipolar pressure transient due to thermo-elastic expansion of the RPE. The pressure waves from the individual pulses of one pulse train show nearly identical transients. The transients differ slightly from different sites on the sample. At higher radiant exposures (>150 mJ/cm2), the OA transients differ from pulse to pulse within a pulse train, which can be attributed to microbubble formation around the strong absorbing melanosomes inside the RPE cells. FFT spectra of the OA transients show slight differences in the frequency spectrum with the different radiant exposures.},
       url = {http://dx.doi.org/10.1117/12.446507},
       type = {Conference Proceedings}
    }
    
  • Schuele, Georg and Joachimmeyer, Elke and Framme, Carsten and Roider, Johann and Birngruber, Reginald and Brinkmann, Ralf: Optoacoustic control system for selective treatment of the retinal pigment epithelium. no. 4256, pp. 71-76,
    BibTeX Link
    @inproceedings{Schuele2001,
       author = {Schuele, Georg and Joachimmeyer, Elke and Framme, Carsten and Roider, Johann and Birngruber, Reginald and Brinkmann, Ralf},
       title = {Optoacoustic control system for selective treatment of the retinal pigment epithelium},
       volume = {4256},
       pages = {71-76},
       note = {10.1117/12.429323},
       abstract = {The selective damage of the retinal pigment epithelium (RPE) is a new treatment method for several retinal diseases. By applying a train of microsecond(s) laser pulses it is possible to selectively damage these cells and simultaneously spare the adjacent photoreceptor and neural tissue. Due to the ophthalmologic invisibility of the RPE cell damage we investigate an optoacoustic (OA) control system to monitor the RPE cell damage. Setup: The irradiation was performed with a frequency doubled Nd:YLF laser by applying a train of +s laser pulses. In vitro, the OA transients were received by an ultrasonic broadband transducer. During treatment an OA contact lens with embedded transducer was used. In vitro: Freshly enucleated porcine RPE samples with CalceinAM as life/death staining were used. Below RPE cell damage threshold a classic thermoelastic transient was found. Above cell damage threshold the OA transient differs form pulse to pulse. This can be explained by microbubble formation around the strong absorbing melanosomes inside the RPE cells. In vivo: We found the same pulse to pulse deviations of the OA transient above the fluoresceine angiographic detectable RPE damage threshold during treatment. This system give us a new approach to non-invasively monitor the selective RPE treatment.},
       url = {http://dx.doi.org/10.1117/12.429323},
       type = {Conference Proceedings}
    }
    
  • Just, T. and Lankenau, E. and Huettmann, G. and Pau, H.W.: Optical coherence tomography as a guide for cochlear implant surgery. in Progress in Biomedical Optics and Imaging, pp. F1-F6, SPIE 6842,
    BibTeX
    @inproceedings{Just,
       author = {Just, T. and Lankenau, E. and Huettmann, G. and Pau, H.W.},
       title = {Optical coherence tomography as a guide for cochlear implant surgery},
       booktitle = {Progress in Biomedical Optics and Imaging},
       editor = {Nikiforos, K. and Bernard, C. and Haishan, Z.},
       publisher = {SPIE 6842},
       pages = {F1-F6},
    
    }
  • Just, T. and Pau, H. W. and Lankenau, E. and Huttmann, G.: OCT in the field of laryngology: further perspectives. no. 7883, pp. 78831W, SPIE,
    BibTeX
    @inproceedings{Just2011,
       author = {Just, T. and Pau, H. W. and Lankenau, E. and Huttmann, G.},
       title = {OCT in the field of laryngology: further perspectives},
       editor = {Nikiforos, Kollias and Bernard, Choi and Haishan, Zeng and Hyun Wook, Kang and Bodo, E. Knudsen and Brian, J. Wong and Justus, F. R. Ilgner and Kenton, W. Gregory and Guillermo, J. Tearney and Laura, Marcu and Henry, Hirschberg and Steen, J. Madsen and Andreas, Mandelis and Anita, Mahadevan-Jansen and Jansen, E. Duco},
       publisher = {SPIE},
       volume = {7883},
       pages = {78831W},
    
    }
  • Schuele, Georg and Huettmann, Gereon and Brinkmann, Ralf: Noninvasive temperature measurements during laser irradiation of the retina with optoacoustic techniques. no. 4611, pp. 64-71, Proc. SPIE,
    BibTeX
    @inproceedings{Schuele,
       author = {Schuele, Georg and Huettmann, Gereon and Brinkmann, Ralf},
       title = {Noninvasive temperature measurements during laser irradiation of the retina with optoacoustic techniques},
       editor = {Fabrice, Manns and Per, G. Soederberg and Arthur, Ho},
       publisher = {Proc. SPIE},
       volume = {4611},
       pages = {64-71},
    }
    
  • Kandulla, J and Elsner, H and Sandeau, J and Birngruber, R and Brinkmann, R: Non-invasive optoacoustic temperature determination during retinal cw-laser treatments. in Proc SPIE, no. 6138, pp. 336-343,
    BibTeX
    @inproceedings{Kandulla2006,
       author = {Kandulla, J and Elsner, H and Sandeau, J and Birngruber, R and Brinkmann, R},
       title = {Non-invasive optoacoustic temperature determination during retinal cw-laser treatments},
       booktitle = {Proc SPIE},
       volume = {6138},
       pages = {336-343},
       type = {Conference Proceedings}
    }
    
  • Horstmann, Jens and Brinkmann, Ralf: Non-contact photoacoustic tomography using holographic full field detection. no. 8800, pp. 880007-880007-6, Proc. SPIE,
    BibTeX Link
    @inproceedings{Horstmann2013,
       author = {Horstmann, Jens and Brinkmann, Ralf},
       title = {Non-contact photoacoustic tomography using holographic full field detection},
       publisher = {Proc. SPIE},
       volume = {8800},
       pages = {880007-880007-6},
       note = {10.1117/12.2033599},
       abstract = {An innovative very fast non-contact imaging technique for Photoacoustic Tomography is introduced. It is based on holographic optical speckle detection of a transiently altering surface topography for the reconstruction of absorbing targets. The surface movement is obtained by parallel recording of speckle phase changes known as Electronic Speckle Pattern Interferometry. Due to parallelized 2-D camera detection and repetitive excitation with variable delay with respect to the image acquisition, data recording of whole volumes for Photoacoustic Imaging can be completed in times far below one second. The size of the detected area is scalable by optical magnification. As a proof of concept, an interferometric setup is realized, capable of surface displacement detection with an axial resolution of less than 3 nm. The potential of the proposed method for in vivo Photoacoustic Imaging is discussed.},
       url = {http://dx.doi.org/10.1117/12.2033599},
       type = {Conference Proceedings}
    }
    
  • Rommerscheid, Jan and Theisen, Dirk and Schmuecker, G. and Brinkmann, Ralf and Broll, R.: Myocardial expression of the vascular endothelial growth factor (VEGF) after endocardial laser revascularization (ELR). no. 4433, pp. 39-44,
    BibTeX Link
    @inproceedings{Rommerscheid2001,
       author = {Rommerscheid, Jan and Theisen, Dirk and Schmuecker, G. and Brinkmann, Ralf and Broll, R.},
       title = {Myocardial expression of the vascular endothelial growth factor (VEGF) after endocardial laser revascularization (ELR)},
       volume = {4433},
       pages = {39-44},
       note = {10.1117/12.446529},
       abstract = {Background. Endocardial laser revascularization (ELR) is a new technique to treat patients with severe coronary artery disease (CAD) in a percutaneous approach. The results show a significant improvement of symptoms, but the mechanism of action is still unknown. One main theory is the angiogenesis for which Vascular Endothelial Growth Factor (VEGF) is the keypromotor. We investigated immunohistochemically the VEGF-expression after ELR in porcine hearts over a timeperiod of four weeks. Methods. ELR was performed with a single-pulse Thulium:YAG laser. 15 pigs were treated with ELR and the hearts were harvested at five timeperiods: directly (group I), 3 days (group II), 1 week (group III), 2 weeks (group IV) and 4 weeks (group V) after ELR. Each group consisted of three pigs. Immunohistochemically the VEGF-expression was assessed by staining with a polyclonal antibody against VEGF and cellcounting using an expression index (VEGF-EI) Results. A maximum of VEGF-expression was found three days (group II) after ELR with a VEGF-EI of 97%. At 1 week (group III) the VEGF-EI was similar high with 93%. Along the timecourse the index decreased to 22% at 4 weeks (groupV). Conclusions. Our findings show that ELR leads to an local upregulation of VEGF around the channels. The resulting angiogenesis could be the mechanism for the relief of angina.},
       url = {http://dx.doi.org/10.1117/12.446529},
       type = {Conference Proceedings}
    }
    
  • Qu, Xiaochao and Norbert, Koop and Li, Zheng and Wang, Jing and Zhang, Zhenxi and Hüttmann, Gereon: Multiphoton fluorescence lifetime imaging of Karpas 299 cells using ACT1 antibody conjugated gold nanoparticles. no. 6630, pp. 66301C-66301C-8,
    BibTeX Link
    @inproceedings{Qu2007,
       author = {Qu, Xiaochao and Norbert, Koop and Li, Zheng and Wang, Jing and Zhang, Zhenxi and Hüttmann, Gereon},
       title = {Multiphoton fluorescence lifetime imaging of Karpas 299 cells using ACT1 antibody conjugated gold nanoparticles},
       volume = {6630},
       pages = {66301C-66301C-8},
       note = {10.1117/12.728239},
       abstract = {Due to the unique optical properties, gold nanoparticles (NPs) can play a useful role in biological cellular imaging as biological probes. Using multiphoton microscopy and fluorescence lifetime imaging (FLIM) system, we recorded the images of Karpas 299 cells incubated without, or with gold NPs, and ACT1 antibodies conjugated with gold NPs. From the FLIM, we can easily discriminate the difference among different experiment conditions due to the distinct lifetime between cells and gold NPs. Our results present that nonconjugated gold NPs are accumulated inside cells, but conjugated gold NPs bind homogeneously and specifically to the surface of cancer cells. For single Karpas 299 cells, the signal is very week when the excitation power is about 10mw; while the power is approximately 28 mw, a very sharp cell imaging can be obtained. For the Karpas 299 incubated with ACT1 conjugated gold NPs, while the excitation power is 10mw, gold NPs have clear fluorescence signal so that the profile of cells can be detected; Signal of gold NPs is very strong when the power arrived in 20mw. These results suggest that the multiphoton lifetime imaging of antibody conjugated gold NPs can support a useful method in diagnosis of cancer.},
       url = {http://dx.doi.org/10.1117/12.728239},
       type = {Conference Proceedings}
    }
    
  • Sandeau, Julien and Caillibotte, Georges and Kandulla, Jochen and Birngruber, Reginald and Apiou-Sbirlea, Gabriela: Modeling of conductive and convective heat transfers in retinal laser treatments. no. 6138, pp. 61381A-61381A-9,
    BibTeX Link
    @inproceedings{Saneau2006,
       author = {Sandeau, Julien and Caillibotte, Georges and Kandulla, Jochen and Birngruber, Reginald and Apiou-Sbirlea, Gabriela},
       title = {Modeling of conductive and convective heat transfers in retinal laser treatments},
       volume = {6138},
       pages = {61381A-61381A-9},
       note = {10.1117/12.673494},
       abstract = {Tumor thermo treatment such as photodynamic therapy (PDT) or transpupillary thermotherapy (TTT) deal with long term and large laser spot exposures. The induced temperature increase is not exactly known [1]. Under these conditions convective heat transfers due to the blood flow in the choroid and the choriocapillaris must be considered in addition to the usually calculated heat conduction. From an existing analytical model defining a unique convective term for the whole fundus irradiated with Gaussian irradiance distribution lasers [2], we developed a numerical one allowing a precise modelling of convection and calculating heating evolution and temperature profiles of the fundus of the eye. The aim of this study is to present the modelling and several comparisons between experimental results [3] and numerical ones concerning the convective heat transfers inside the fundus of the eye.},
       url = {http://dx.doi.org/10.1117/12.673494},
       type = {Conference Proceedings}
    }
    
  • Evers, Michael and Welford, David and Mansteine, Dieter and Birngruber, Reginald: Mid-infrared laser spectroscopy using a tunable gain-switched Cr2+: ZnSe laser. in Studierendentagung, Unversität zu Lübeck,
    BibTeX
    @inproceedings{Ever2013,
       author = {Evers, Michael and Welford, David and Mansteine, Dieter and Birngruber, Reginald},
       title = {Mid-infrared laser spectroscopy using a tunable gain-switched Cr2+: ZnSe laser},
       booktitle = {Studierendentagung},
       publisher = {Unversität zu Lübeck},
       type = {Conference Proceedings}
    }
    
  • Horneffer, V. and Vogel, A. and Sägmüller, B. and Schütze, K.: Microdissection, catapulting, and microinjection of biologic specimens with femtosecond laser pulses. in SPIE/OSA Conference on Biomedical Optics ECBO,12.-16.06.2005,
    BibTeX
    @inproceedings{Horneffer,
       author = {Horneffer, V. and Vogel, A. and Sägmüller, B. and Schütze, K.},
       title = {Microdissection, catapulting, and microinjection of biologic specimens with femtosecond laser pulses},
       booktitle = {SPIE/OSA Conference on Biomedical Optics ECBO,12.-16.06.2005},
    }
  • Pan, Y. and Engelhardt, R. and Rosperich, J. and Hüttmann, G. and Birngruber, R.: Measurement of Optical-Transport-Coefficients of Intralipid in Visible and NIR Range. in Proc. SPIE, no. 2134A, pp. 354-363,
    BibTeX
    @inproceedings{Pan,
       author = {Pan, Y. and Engelhardt, R. and Rosperich, J. and Hüttmann, G. and Birngruber, R.},
       title = {Measurement of Optical-Transport-Coefficients of Intralipid in Visible and NIR Range},
       booktitle = {Proc. SPIE},
       volume = {2134A},
       pages = {354-363},
    
    }
    
  • Apitz, Ingo and Vogel, Alfred: Material ejection in Q-switched Er:YAG laser ablation of water, liver, and skin. no. 4961, pp. 48-59, SPIE,
    BibTeX
    @inproceedings{Apitz,
       author = {Apitz, Ingo and Vogel, Alfred},
       title = {Material ejection in Q-switched Er:YAG laser ablation of water, liver, and skin},
       editor = {Steven, L. Jacques and Donald, D. Duncan and Sean, J. Kirkpatrick and Andres, Kriete},
       publisher = {SPIE},
       volume = {4961},
       pages = {48-59},
    }
    
  • Koch, Peter and Huettmann, Gereon and Schleiermacher, Hansfrieder and Eicholz, Joerg and Koch, Edmund: Linear OCT system with down conversion of the fringe pattern. no. 5316, pp. 260-267, SPIE,
    BibTeX
    @inproceedings{Koch,
       author = {Koch, Peter and Huettmann, Gereon and Schleiermacher, Hansfrieder and Eicholz, Joerg and Koch, Edmund},
       title = {Linear OCT system with down conversion of the fringe pattern},
       editor = {Valery, V. Tuchin and Joseph, A. Izatt and James, G. Fujimoto},
       publisher = {SPIE},
       volume = {5316},
       pages = {260-267},
    
    }
  • Vogel, Alfred and Noack, Joachim and Nahen, Kester and Theisen, Dirk and Birngruber, Reginald and Hammer, Daniel X and Noojin, Gary D and Rockwell, Benjamin A: Laser-induced breakdown in the eye at pulse durations from 80 ns to 100 fs. in BiOS`98 International Biomedical Optics Symposium, pp. 34-49, International Society for Optics and Photonics,
    BibTeX
    @inproceedings{Vogel1998,
       author = {Vogel, Alfred and Noack, Joachim and Nahen, Kester and Theisen, Dirk and Birngruber, Reginald and Hammer, Daniel X and Noojin, Gary D and Rockwell, Benjamin A},
       title = {Laser-induced breakdown in the eye at pulse durations from 80 ns to 100 fs},
       booktitle = {BiOS'98 International Biomedical Optics Symposium},
       publisher = {International Society for Optics and Photonics},
       pages = {34-49},
       type = {Conference Proceedings}
    }
    
  • Radt, Benno and Serbin, Jesper and Lange, Bjoern I. and Birngruber, Reginald and Huettmann, Gereon: Laser-generated micro- and nanoeffects: inactivation of proteins coupled to gold nanoparticles with nano- and picosecond pulses. no. 4433, pp. 16-24, SPIE,
    BibTeX
    @inproceedings{Radt,
       author = {Radt, Benno and Serbin, Jesper and Lange, Bjoern I. and Birngruber, Reginald and Huettmann, Gereon},
       title = {Laser-generated micro- and nanoeffects: inactivation of proteins coupled to gold nanoparticles with nano- and picosecond pulses},
       editor = {Reginald, Birngruber and Hubert van den, Bergh},
       publisher = {SPIE},
       volume = {4433},
       pages = {16-24},
    
    }
    
  • Vogel, Alfred and Venugopalan, Vasan: Kinetics of phase transitions in pulsed IR laser ablation of biological tissues. no. 4961, pp. 66-74, SPIE,
    BibTeX
    @inproceedings{Vogel,
       author = {Vogel, Alfred and Venugopalan, Vasan},
       title = {Kinetics of phase transitions in pulsed IR laser ablation of biological tissues},
       editor = {Steven, L. Jacques and Donald, D. Duncan and Sean, J. Kirkpatrick and Andres, Kriete},
       publisher = {SPIE},
       volume = {4961},
       pages = {66-74},
    }
    
  • Theisen-Kunde, D; Wolken, H; Ellebrecht, D; Danicke, V; Wurster, L; Kleemann, M and Birngruber, R: Investigation of water spray to reduce collateral thermal damage during laser resection of soft tissue. no. 8803, pp. 88030F-88030F-4,
    BibTeX Link
    @inproceedings{Theisen-Kunde2013,
       author = {Theisen-Kunde, D; Wolken, H; Ellebrecht, D; Danicke, V; Wurster, L; Kleemann, M and Birngruber, R},
       title = {Investigation of water spray to reduce collateral thermal damage during laser resection of soft tissue},
       volume = {8803},
       pages = {88030F-88030F-4},
       note = {10.1117/12.2032384},
       abstract = {To reduce unwanted collateral thermal damage to surrounding tissue and organs during laparoscopic laser dissection (cw, wavelength: 1.9μm) of porcine liver water spray was used. Size and amount of the produced water droplets of the water spray were photographed by short time imaging and analyzed by imaging software. At in vivo measurements on fresh porcine liver the depth of thermal damage was reduced by 85 % with water spray and the lateral size of thermal damage at the tissue surface could be reduced by 67%. This results show that especially for laparoscopic laser surgery water spray application might be a useful tool to avoid unwanted collateral thermal damage.},
       url = {http://dx.doi.org/10.1117/12.2032384},
       type = {Conference Proceedings}
    }
    
  • Theisen-Kunde, D. and Wolken, H. and Ellebrecht, D. and Danicke, V. and Wurster, L. and Kleemann, M. and Birngruber, R.: Investigation of water spray to reduce collateral thermal damage during laser resection of soft tissue. no. 8803, pp. 88030F-88030F-4,
    BibTeX Link
    @inproceedings{Theisen-Kunde2013,
       author = {Theisen-Kunde, D. and Wolken, H. and Ellebrecht, D. and Danicke, V. and Wurster, L. and Kleemann, M. and Birngruber, R.},
       title = {Investigation of water spray to reduce collateral thermal damage during laser resection of soft tissue},
       volume = {8803},
       pages = {88030F-88030F-4},
       note = {10.1117/12.2032384},
       abstract = {To reduce unwanted collateral thermal damage to surrounding tissue and organs during laparoscopic laser dissection (cw, wavelength: 1.9μm) of porcine liver water spray was used. Size and amount of the produced water droplets of the water spray were photographed by short time imaging and analyzed by imaging software. At in vivo measurements on fresh porcine liver the depth of thermal damage was reduced by 85 % with water spray and the lateral size of thermal damage at the tissue surface could be reduced by 67%. This results show that especially for laparoscopic laser surgery water spray application might be a useful tool to avoid unwanted collateral thermal damage.},
       url = {http://dx.doi.org/10.1117/12.2032384},
       type = {Conference Proceedings}
    }
    
  • Orzekowsky-Schroeder, Regina and Klinger, Antje and Schuth, Anna and Freidank, Sebastian and Huttmann, Gereon and Gebert, Andreas and Vogel, Alfred: Intravital real-time study of tissue response to controlled laser-induced cavitation using 500-ps UV laser pulses focused in murine gut mucosa under online dosimetry and spectrally resolved 2-photon microscopy. no. 7568, pp. 756815, SPIE,
    BibTeX
    @inproceedings{Orzekowsky2010,
       author = {Orzekowsky-Schroeder, Regina and Klinger, Antje and Schuth, Anna and Freidank, Sebastian and Huttmann, Gereon and Gebert, Andreas and Vogel, Alfred},
       title = {Intravital real-time study of tissue response to controlled laser-induced cavitation using 500-ps UV laser pulses focused in murine gut mucosa under online dosimetry and spectrally resolved 2-photon microscopy},
       editor = {Daniel, L. Farkas and Dan, V. Nicolau and Robert, C. Leif},
       publisher = {SPIE},
       volume = {7568},
       pages = {756815},
    
    }
  • Stoehr, Hardo and Ptaszynski, Lars and Fritz, Andreas and Brinkmann, Ralf: Interferometric optical online dosimetry for selective retina treatment (SRT). no. 6426, pp. 642619-642619-7,
    BibTeX Link
    @inproceedings{Stoehr2007,
       author = {Stoehr, Hardo and Ptaszynski, Lars and Fritz, Andreas and Brinkmann, Ralf},
       title = {Interferometric optical online dosimetry for selective retina treatment (SRT)},
       volume = {6426},
       pages = {642619-642619-7},
       note = {10.1117/12.708521},
       abstract = {In selective retina treatment (SRT) spatial confined tissue damage in the absorbing retinal pigment epithelium (RPE) is obtained by applying microsecond laser pulses. The damage in the RPE is caused by transient microbubbles forming around the laser heated melanin granules inside the cells. For treatment of RPE related diseases, SRT is thought to share the therapeutic benefits of conventional photocoagulation but without affecting the photoreceptors. A drawback for effective clinical SRT is that the laser-induced lesions are ophthalmoscopically invisible. Therefore, a real-time feedback system for dosimetry is demanded in order to avoid undertreatment or unwanted collateral damage to the adjacent tissue. We develop a dosimetry system which uses optical interferometry for the detection of the transient microbubbles. The system is based on an optical fiber interferometer which is operated with a laser diode at 830nm. We present current results obtained with porcine RPE explants in vitro and complete porcine eye globes ex vivo.},
       url = {http://dx.doi.org/10.1117/12.708521},
       type = {Conference Proceedings}
    }
    
  • Stoehr, Hardo and Ptaszynski, Lars and Fritz, Andreas and Brinkmann, Ralf: Interferometric optical online dosimetry for selective retina treatment (SRT). no. 6426, pp. 642619-642619-7,
    BibTeX
    @inproceedings{Stoehr2007,
       author = {Stoehr, Hardo and Ptaszynski, Lars and Fritz, Andreas and Brinkmann, Ralf},
       title = {Interferometric optical online dosimetry for selective retina treatment (SRT)},
       volume = {6426},
       pages = {642619-642619-7},
       note = {10.1117/12.708521},
       abstract = {In selective retina treatment (SRT) spatial confined tissue damage in the absorbing retinal pigment epithelium (RPE) is obtained by applying microsecond laser pulses. The damage in the RPE is caused by transient microbubbles forming around the laser heated melanin granules inside the cells. For treatment of RPE related diseases, SRT is thought to share the therapeutic benefits of conventional photocoagulation but without affecting the photoreceptors. A drawback for effective clinical SRT is that the laser-induced lesions are ophthalmoscopically invisible. Therefore, a real-time feedback system for dosimetry is demanded in order to avoid undertreatment or unwanted collateral damage to the adjacent tissue. We develop a dosimetry system which uses optical interferometry for the detection of the transient microbubbles. The system is based on an optical fiber interferometer which is operated with a laser diode at 830nm. We present current results obtained with porcine RPE explants in vitro and complete porcine eye globes ex vivo.},
       url = {http://dx.doi.org/10.1117/12.708521},
       type = {Conference Proceedings}
    }
    
  • Vogel, Alfred and Brujan, Emil A and Schmidt, Peter and Nahen, Kester: Interaction of Laser-Produced Cavitation Bubbles with Elastic Boundaries. in IUTAM Symposium on Free Surface Flows, pp. 327-335, Springer,
    BibTeX
    @inproceedings{Vogel2001,
       author = {Vogel, Alfred and Brujan, Emil A and Schmidt, Peter and Nahen, Kester},
       title = {Interaction of Laser-Produced Cavitation Bubbles with Elastic Boundaries},
       booktitle = {IUTAM Symposium on Free Surface Flows},
       publisher = {Springer},
       pages = {327-335},
       ISBN = {9401038546},
       type = {Conference Proceedings}
    }
    
  • Vogel, Alfred and Brujan, Emil A and Schmidt, Peter and Nahen, Kester: Interaction of laser-produced cavitation bubbles with an elastic tissue model. in BiOS 2001 The International Symposium on Biomedical Optics, pp. 167-177, International Society for Optics and Photonics,
    BibTeX
    @inproceedings{Vogel2001,
       author = {Vogel, Alfred and Brujan, Emil A and Schmidt, Peter and Nahen, Kester},
       title = {Interaction of laser-produced cavitation bubbles with an elastic tissue model},
       booktitle = {BiOS 2001 The International Symposium on Biomedical Optics},
       publisher = {International Society for Optics and Photonics},
       pages = {167-177},
       type = {Conference Proceedings}
    }
    
  • Vogel, Alfred and Nahen, Kester and Theisen, Dirk and Birngruber, Reginald and Thomas, Robert J and Rockwell, Benjamin A: Influence of optical aberrations on laser-induced plasma formation in water and their consequences for intraocular photodisruption. in BiOS`98 International Biomedical Optics Symposium, pp. 120-131, International Society for Optics and Photonics,
    BibTeX
    @inproceedings{Vogel1998,
       author = {Vogel, Alfred and Nahen, Kester and Theisen, Dirk and Birngruber, Reginald and Thomas, Robert J and Rockwell, Benjamin A},
       title = {Influence of optical aberrations on laser-induced plasma formation in water and their consequences for intraocular photodisruption},
       booktitle = {BiOS'98 International Biomedical Optics Symposium},
       publisher = {International Society for Optics and Photonics},
       pages = {120-131},
       type = {Conference Proceedings}
    }
    
  • Herrmann, Katharina and Flöhr, Christian and Stalljohann, Jens and Apiou-Sbirlea, Gabriela and Kandulla, Jochen and Birngruber, Reginald and Brinkmann, Ralf: Influence of choroidal perfusion on retinal temperature increase during retinal laser treatments. no. 6632, pp. 66321D-66321D-7,
    BibTeX Link
    @inproceedings{Herrmann2007,
       author = {Herrmann, Katharina and Flöhr, Christian and Stalljohann, Jens and Apiou-Sbirlea, Gabriela and Kandulla, Jochen and Birngruber, Reginald and Brinkmann, Ralf},
       title = {Influence of choroidal perfusion on retinal temperature increase during retinal laser treatments},
       volume = {6632},
       pages = {66321D-66321D-7},
       note = {10.1117/12.728222},
       abstract = {In most retinal laser treatments the therapeutic effect is initiated by a transient temperature increase at and around the retinal pigment epithelium (RPE). Especially in long exposure time treatments like Transpupillary Thermotherapy (TTT) choroidal perfusion has a strong influence on the realized temperature at the fundus. The fundus blood circulation and therefore the heat dissipation is influenced by the intraocular pressure (IOP), which is investigated in the study presented here. In order to reduce the choroidal perfusion, the IOP is increased by injection of physiological saline solution into the eye of anaesthetized rabbits. The fundus is irradiated with 3.64 W/cm2 by means of a TTT-laser (λ = 810 nm) for t = 20 s causing a retinal temperature increase. Realtime temperature determination at the irradiated spot is achieved by a non invasive optoacoustic technique. Perfusion can be reduced by increasing IOP, which leads to different temperature increases when irradiating the retina. This should be considered for long time laser treatments.},
       url = {http://dx.doi.org/10.1117/12.728222},
       type = {Conference Proceedings}
    }
    
  • Huettmann, Gereon and Radt, Benno and Serbin, Jesper and Birngruber, Reginald: Inactivation of proteins by irradiation of gold nanoparticles with nano- and picosecond laser pulses. no. 5142, pp. 88-95, SPIE,
    BibTeX
    @inproceedings{Hüttmann2003,
       author = {Huettmann, Gereon and Radt, Benno and Serbin, Jesper and Birngruber, Reginald},
       title = {Inactivation of proteins by irradiation of gold nanoparticles with nano- and picosecond laser pulses},
       editor = {Rudolf, W. Steiner},
       publisher = {SPIE},
       volume = {5142},
       pages = {88-95},
    }
    
    
    
    
  • Alt, C and Framme, C and Schnell, S and Schuele, G and Brinkmann, R and Lin, C P: In vivo and in vitro Selective Targeting of the Retinal Pigment Epithelium (RPE) Using a Laser-Scanning Device. in Proc SPIE, no. 4611, pp. 59-63,
    BibTeX
    @inproceedings{Alt2002,
       author = {Alt, C and Framme, C and Schnell, S and Schuele, G and Brinkmann, R and Lin, C P},
       title = {In vivo and in vitro Selective Targeting of the Retinal Pigment Epithelium (RPE) Using a Laser-Scanning Device},
       booktitle = {Proc SPIE},
       volume = {4611},
       pages = {59-63},
       type = {Conference Proceedings}
    }
    
  • Spahr, Hendrik and Hillmann, Dierck and Hain, Carola and Pfäffle, Clara and Sudkamp, Helge and Franke, Gesa and Hüttmann, Gereon: Imaging vascular dynamics in human retina using full-field swept-source optical coherence tomography (Conference Presentation). no. 9697, pp. 96970E-96970E-1,
    BibTeX Link
    @inproceedings{Spahr2016,
       author = {Spahr, Hendrik and Hillmann, Dierck and Hain, Carola and Pfäffle, Clara and Sudkamp, Helge and Franke, Gesa and Hüttmann, Gereon},
       title = {Imaging vascular dynamics in human retina using full-field swept-source optical coherence tomography (Conference Presentation)},
       volume = {9697},
       pages = {96970E-96970E-1},
       note = {10.1117/12.2214303},
       abstract = {We demonstrate a new non-invasive method to assess the functional condition of the retinal vascular system. Phase-sensitive full-field swept-source optical coherence tomography (PhS-FF-SS-OCT) is used to investigate retinal vascular dynamics at unprecedented temporal resolution. Motion of retinal tissue, that is induced by expansion of the vessels therein, is measured with an accuracy of about 10 nm. The pulse shape of arterial and venous pulsation, their temporal delay as well as the frequency dependent pulse propagation through the capillary bed are determined. For the first time, imaging speed and motion sensitivity are sufficient for a direct measurement of pulse waves propagating with more than 600 mm/s in retinal vessels of a healthy young subject.},
       url = {http://dx.doi.org/10.1117/12.2214303},
       type = {Conference Proceedings}
    }
    
  • Muller, Heike H. and Ptaszynski, Lars and Schlott, Kerstin and Bonin, Tim and Bever, Marco and Koinzer, Stefan and Birngruber, Reginald and Brinkmann, Ralf and Huttmann, Gereon: Imaging of temperature distribution and retinal tissue changes during photocoagulation by high speed OCT. no. 7889, pp. 78890E, SPIE,
    BibTeX
    @inproceedings{Müller2011,
       author = {Muller, Heike H. and Ptaszynski, Lars and Schlott, Kerstin and Bonin, Tim and Bever, Marco and Koinzer, Stefan and Birngruber, Reginald and Brinkmann, Ralf and Huttmann, Gereon},
       title = {Imaging of temperature distribution and retinal tissue changes during photocoagulation by high speed OCT},
       editor = {James, G. Fujimoto and Joseph, A. Izatt and Valery, V. Tuchin},
       publisher = {SPIE},
       volume = {7889},
       pages = {78890E},
    
    }
  • Spahr, Hendrik and Rudolph, Linda and Muller, Heike and Birngruber, Reginald and Huttmann, Gereon: Imaging of photothermal tissue expansion via phase sensitive optical coherence tomography. no. 8213, pp. 82131S, SPIE,
    BibTeX
    @inproceedings{Spahr2012,
       author = {Spahr, Hendrik and Rudolph, Linda and Muller, Heike and Birngruber, Reginald and Huttmann, Gereon},
       title = {Imaging of photothermal tissue expansion via phase sensitive optical coherence tomography},
       editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
       publisher = {SPIE},
       volume = {8213},
       pages = {82131S},
    
    }
  • Pieper, Mario and Schulz-Hildebrandt, Hinnerk and Hüttmann, Gereon and König, Peter: Imaging of mucus clearance in the airways of living spontaneously breathing mice by optical coherence microscopy (Conference Presentation). no. 9691, pp. 969116-969116-1,
    BibTeX Link
    @inproceedings{Pieper2016,
       author = {Pieper, Mario and Schulz-Hildebrandt, Hinnerk and Hüttmann, Gereon and König, Peter},
       title = {Imaging of mucus clearance in the airways of living spontaneously breathing mice by optical coherence microscopy (Conference Presentation)},
       volume = {9691},
       pages = {969116-969116-1},
       note = {10.1117/12.2209054},
       abstract = {Mucus transport is essential to remove inhaled particles and pathogens from the lung. Impaired removal of mucus often results in worsening of lung diseases. To understand the mechanisms of mucus transport and to monitor the impact of therapeutic strategies, it is essential to visualize airways and mucus in living animals without disturbing transport processes by intubation or surgically opening the airways. We developed a custom-built optical coherence microscope (OCM) providing a lateral and axial resolution of approximately 1.5 µm with a field of view of 2 mm at up to 150 images/s. Images of the intact trachea and its mucus transport were recorded in anesthetized spontaneously breathing mice. NaCl solution (0.9% and 7%) or Lipopolysaccharide were applied intranasally. OCM resolved detailed structure of the trachea and enabled measuring the airway surface liquid (ASL) thickness through the tracheal wall. Without stimulation, the amount of ASL was only a few µm above the epithelium and remained constant. After intranasal application of 30 µl saline at different concentrations, an early fast cough-like fluid removal with velocities higher than 1 mm/s was observed that removed a high amount of liquid. The ASL thickness increased transiently and quickly returned to levels before stimulation. In contrast to saline, application of Lipopolysaccharide induced substantial mucus release and an additional slow mucus transport by ciliary beating (around 100 µm/s) towards the larynx was observed. In conclusion, OCM is appropriate unique tool to study mechanisms of mucus transport in the airways and effects of therapeutic interventions in living animals.},
       url = {http://dx.doi.org/10.1117/12.2209054},
       type = {Conference Proceedings}
    }
    
  • Hüttmann, G. and Orzekowsky-Schröder, R.: Imaging of immune cell dynamics in small intestine and the eye by 2-photon microcopy. in 7th Workshop on Advanced Multiphoton and Fluorescence Lifetime Imaging Techniques (FLIM 2012),
    BibTeX
    @inproceedings{Hüttmann2012,
       author = {Hüttmann, G. and Orzekowsky-Schröder, R.},
       title = {Imaging of immune cell dynamics in small intestine and the eye  by 2-photon microcopy},
       booktitle = {7th Workshop on Advanced Multiphoton and Fluorescence Lifetime Imaging Techniques (FLIM 2012)},
       abstract = {Autofluorescence based 2-photon microscopy was investigated as a
    tool for studying the dynamics of immunological processes in vivo. Nearly
    all tissue components were simultaneously visible by autofluorescence and a
    nearly complete visualization of tissue architecture was possible. Within
    the tissue, immune competent cells like lymphocytes, macrophages and
    dendritic cells were visualized in their dynamic interaction with other
    cells or surrounding tissues.
    Immunological processes were studied in the small intestine and at the
    surface of the eye. Excitation and emission spectra of the different mucosal
    tissue components were quantitatively determined and a compared to the
    respective spectra of endogenous chromophores. It was shown, that by using
    only two excitation wavelengths within the tuning range of a Ti:Saphire
    laser enterocytes, antigen presenting cells and lysosomes of the small
    intestine could be discriminated based on the excitation and emission
    properties. By additionally using an intravital nuclear stain, motion of
    lymphocytes in the lamina propria and the epithelium of small intestine
    villi was quantitatively analyzed. 
    
    2-photon microscopy was also a powerful tool for studying the conjunctiva
    and cornea of the eye. Lymphocyte dynamics and uptake of microspheres or
    fluorescing heat-inactivated E. coli was followed over time in the
    conjunctiva-associated lymphoid tissue of mice. In a different mouse model
    of suture induced corneal hem- and lymphangiogenesis, immune cell migration
    into lymphatic vessels and luminal transport of individual cells was
    observed in vivo.
    
    Autofluorescence based 2-photon intravital microscopy is a valuable tool to
    study dynamic immunological processes. While tissue autofluorescence gives a
    good overview over all relevant structures and allows for discriminating
    different cell types by spectral analysis, the additional combination of
    specific staining with external dyes or fluorescent proteins is easily
    possible and enhances the potential of the technique further. },
    
    }
  • Hillmann, Dierck and Luhrs, Christian and Bonin, Tim and Koch, Peter and Vogel, Alfred and Huttmann, Gereon: Holoscopy: holographic optical coherence tomography. no. 8091, pp. 80911H, Proc. SPIE,
    BibTeX Link
    @inproceedings{Hillmann2011,
       author = {Hillmann, Dierck and Luhrs, Christian  and Bonin, Tim  and Koch, Peter and Vogel, Alfred  and Huttmann, Gereon },
       title = {Holoscopy: holographic optical coherence tomography},
       editor = {Rainer, A. Leitgeb and Brett, E. Bouma},
       publisher = {Proc. SPIE},
       volume = {8091},
       pages = {80911H},
       url = {http://link.aip.org/link/?PSI/8091/80911H/1
    http://dx.doi.org/10.1117/12.889485},
       type = {Conference Proceedings}
    }
    
  • Franke, Gesa Lilith and Hillmann, Dierck and Claussen, Thorsten and Luhrs, Christian and Koch, Peter and Huttmann, Gereon: High resolution holoscopy. no. 8213, pp. 821324, SPIE,
    BibTeX
    @inproceedings{Franke2012,
       author = {Franke, Gesa Lilith and Hillmann, Dierck and Claussen, Thorsten and Luhrs, Christian and Koch, Peter and Huttmann, Gereon},
       title = {High resolution holoscopy},
       editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
       publisher = {SPIE},
       volume = {8213},
       pages = {821324},
    
    }
  • Hüttmann, G. and Achtelik, W. and Löning, M. and Sommer, K. and Diddens, H.: Fluorescence microscopy studies on ALA sensitized tissues. in SPIE Proc., no. 2926, pp. 24-31,
    BibTeX
    @inproceedings{Hüttmann,
       author = {Hüttmann, G. and Achtelik, W. and Löning, M. and Sommer, K. and Diddens, H.},
       title = {Fluorescence microscopy studies on ALA sensitized tissues},
       booktitle = {SPIE Proc.},
       volume = {2926},
       pages = {24-31},
    
    }
    
  • Xie, Y. and Bonin, T. and Loeffler, S. and Huettmann, G. and Tronnier, V. and Hofmann, U. G.: Fiber spectral domain optical coherence tomography for in vivo rat brain imaging. no. 7715, pp. 77152F, SPIE,
    BibTeX
    @inproceedings{Xie,
       author = {Xie, Y. and Bonin, T. and Loeffler, S. and Huettmann, G. and Tronnier, V. and Hofmann, U. G.},
       title = {Fiber spectral domain optical coherence tomography for in vivo rat brain imaging},
       editor = {Jurgen, Popp and Wolfgang, Drexler and Valery, V. Tuchin and Dennis, L. Matthews},
       publisher = {SPIE},
       volume = {7715},
       pages = {77152F},
    
    }
  • Vogel, A. and Noack, J. and Hüttmann, G. and Linz, N. and Freidank, S. and Paltauf, G.: Femtosecond laser nanosurgery of biological cells and tissues. in 4th International Congress on Laser Advanced Materials Processing,
    BibTeX
    @inproceedings{Vogel2006,
       author = {Vogel, A. and Noack, J. and Hüttmann, G. and Linz, N. and Freidank, S. and Paltauf, G.},
       title = {Femtosecond laser nanosurgery of biological cells and tissues},
       booktitle = {4th International Congress on Laser Advanced Materials Processing}
    }
  • Otte, Christoph and Huttmann, Gereon and Schlaefer, Alexander: Feasibiliy of optical detection of soft tissue deformation during needle insertion. no. 8316, pp. 83160V, SPIE,
    BibTeX
    @inproceedings{Otte,
       author = {Otte, Christoph and Huttmann, Gereon and Schlaefer, Alexander},
       title = {Feasibiliy of optical detection of soft tissue deformation during needle insertion},
       editor = {David, R. Holmes, III and Kenneth, H. Wong},
       publisher = {SPIE},
       volume = {8316},
       pages = {83160V},
    
    }
  • Guerra III, Arnold and Venugopalan, Vasan and Nahen, Kester and Vogel, Alfred: Experimental investigation of optical breakdown using nanosecond 532-nm and 1064-nm laser pulses delivered at high numerical aperture. in BiOS 2001 The International Symposium on Biomedical Optics, pp. 74-82, International Society for Optics and Photonics,
    BibTeX
    @inproceedings{Guerra2001,
       author = {Guerra III, Arnold and Venugopalan, Vasan and Nahen, Kester and Vogel, Alfred},
       title = {Experimental investigation of optical breakdown using nanosecond 532-nm and 1064-nm laser pulses delivered at high numerical aperture},
       booktitle = {BiOS 2001 The International Symposium on Biomedical Optics},
       publisher = {International Society for Optics and Photonics},
       pages = {74-82},
       type = {Conference Proceedings}
    }
    
  • Daniltchenko, D. and Sachs, M. and Lankenau, E. and König, F. and Burckhardt, M. and Hüttmann, G. and Kristiansen, G. and Schnorr, D. and Al-Shukri, S. and Löning, S.: Ex vivo and in vivo topographics studies of bladder by optical coherence tomography. in Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI, no. 5771, pp. 209-14, Proceedings 2005,
    BibTeX
    @inproceedings{Daniltchenko,
       author = {Daniltchenko, D. and Sachs, M. and Lankenau, E. and König, F. and Burckhardt, M. and Hüttmann, G. and Kristiansen, G. and Schnorr, D. and Al-Shukri, S. and Löning, S.},
       title = {Ex vivo and in vivo topographics studies of bladder by optical coherence tomography},
       booktitle = {Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI},
       editor = {Tuchin, V.},
       publisher = {Proceedings 2005},
       volume = {5771},
       pages = {209-14},
    
    }
  • Vogel, Alfred and Noack, Joachim and Nahen, Kester and Theisen, Dirk and Busch, Stefan and Parlitz, Ulrich and Hammer, Daniel X and Noojin, Gary D and Rockwell, Benjamin A and Birngruber, Reginald: Energy balance of optical breakdown in water. in BiOS`98 International Biomedical Optics Symposium, pp. 168-179, International Society for Optics and Photonics,
    BibTeX
    @inproceedings{Vogel1998,
       author = {Vogel, Alfred and Noack, Joachim and Nahen, Kester and Theisen, Dirk and Busch, Stefan and Parlitz, Ulrich and Hammer, Daniel X and Noojin, Gary D and Rockwell, Benjamin A and Birngruber, Reginald},
       title = {Energy balance of optical breakdown in water},
       booktitle = {BiOS'98 International Biomedical Optics Symposium},
       publisher = {International Society for Optics and Photonics},
       pages = {168-179},
       type = {Conference Proceedings}
    }
    
  • Brujan, Emil-Alexandru and Nahen, Kester and Schmidt, Peter and Vogel, Alfred: Dynamics of laser-induced cavitation bubbles near an elastic boundary used as a tissue phantom. in NONLINEAR ACOUSTICS AT THE TURN OF THE MILLENNIUM: ISNA 15, 15th International Symposium, no. 524, pp. 381-384, AIP Publishing,
    BibTeX
    @inproceedings{Brujan2000,
       author = {Brujan, Emil-Alexandru and Nahen, Kester and Schmidt, Peter and Vogel, Alfred},
       title = {Dynamics of laser-induced cavitation bubbles near an elastic boundary used as a tissue phantom},
       booktitle = {NONLINEAR ACOUSTICS AT THE TURN OF THE MILLENNIUM: ISNA 15, 15th International Symposium},
       publisher = {AIP Publishing},
       volume = {524},
       pages = {381-384},
       ISBN = {0094-243X},
       type = {Conference Proceedings}
    }
    
  • Fritz, Andreas and Zegelin, Andrea and Ptaszynski, Lars and Birngruber, Reginald and Brinkmann, Ralf: Dynamics of laser induced micro bubble clusters on tissue phantoms. no. 7885, pp. 78850S-78850S-6,
    BibTeX
    @inproceedings{Fritz2011,
       author = {Fritz, Andreas and Zegelin, Andrea and Ptaszynski, Lars and Birngruber, Reginald and Brinkmann, Ralf},
       title = {Dynamics of laser induced micro bubble clusters on tissue phantoms},
       volume = {7885},
       pages = {78850S-78850S-6},
       note = {10.1117/12.875031},
       abstract = {Selective retina treatment (SRT) is a laser based method to treat retinal diseases associated with disorders of the retinal pigment epithelium (RPE) while preserving photoreceptors and choroid. Applying microsecond laser pulses to the 100- 200 strongly absorbing melanin granules inside the RPE cells induces transient micro bubbles which disrupt the cells. Aim of this work is to understand bubble dynamics in clusters with respect to the influence of the adjacent retina. Bubble dynamics were investigated in vitro on porcine RPE. An about 200 μm thick layer of agarose gel was applied to the RPE layer in order to simulate the mechanical properties of retina. Different laser pulse durations from 1 ns (532 nm, Nd:YAG) to 1.7 μs (527 nm, Nd:YLF) were used. The bubbles were investigated interferometrically (fiber interferometer @ 830 nm) and with fast flash photography (25 ns flash duration). Bubble lifetimes were measured. The results show that with retina phantoms the bubble formation threshold was reached at 2.5 times higher irradiation than without retina phantom for 1.7 μs laser pulses. The microbubbles generated with 1 ns laser pulses were almost not influenced by the agarose layer. Irradiation twofold over bubble formation threshold resulted in 3.5 times longer bubble lifetimes for μs and 2 times longer for ns pulse durations, respectively.},
       url = {http://dx.doi.org/10.1117/12.875031},
       type = {Conference Proceedings}
    }
    
  • Fritz, Andreas and Ptaszynski, Lars and Stoehr, Hardo and Brinkmann, Ralf: Dynamics and detection of laser induced microbubbles in the retinal pigment epithelium (RPE). no. 6632, pp. 66321C-66321C-11,
    BibTeX Link
    @inproceedings{Fritz2007,
       author = {Fritz, Andreas and Ptaszynski, Lars and Stoehr, Hardo and Brinkmann, Ralf},
       title = {Dynamics and detection of laser induced microbubbles in the retinal pigment epithelium (RPE)},
       volume = {6632},
       pages = {66321C-66321C-11},
       note = {10.1117/12.728344},
       abstract = {Selective Retina Treatment (SRT) is a new method to treat eye diseases associated with disorders of the RPE. Selective RPE cell damage is achieved by applying a train of 1.7 μs laser pulses at 527 nm. The treatment of retinal diseases as e.g. diabetic maculopathy (DMP), is currently investigated within clinical studies, however 200 ns pulse durations are under investigation. Transient micro bubbles in the retinal pigment epithelium (RPE) are expected to be the origin of cell damage due to irradiation with laser pulses shorter than 50 μs. The bubbles emerge at the strongly absorbing RPE melanosomes. Cell membrane disruption caused by the transient associated volume increase is expected to be the origin of the angiographically observed RPE leakage. We investigate micro bubble formation and dynamics in porcine RPE using pulse durations of 150 ns. A laser interferometry system at 830 nm with the aim of an online dosimetry control for SRT was developed. Bubble formation was detected interferometrically and by fast flash photography. A correlation to cell damage observed with a vitality stain is found. A bubble detection algorithm is presented.},
       url = {http://dx.doi.org/10.1117/12.728344},
       type = {Conference Proceedings}
    }
    
  • Fritz, Andreas and Ptaszynski, Lars and Stoehr, Hardo and Brinkmann, Ralf: Dynamics and detection of laser induced microbubbles in the retinal pigment epithelium (RPE). no. 6632, pp. 66321C-66321C-11,
    BibTeX
    @inproceedings{Fritz2007,
       author = {Fritz, Andreas and Ptaszynski, Lars and Stoehr, Hardo and Brinkmann, Ralf},
       title = {Dynamics and detection of laser induced microbubbles in the retinal pigment epithelium (RPE)},
       volume = {6632},
       pages = {66321C-66321C-11},
       note = {10.1117/12.728344},
       abstract = {Selective Retina Treatment (SRT) is a new method to treat eye diseases associated with disorders of the RPE. Selective RPE cell damage is achieved by applying a train of 1.7 μs laser pulses at 527 nm. The treatment of retinal diseases as e.g. diabetic maculopathy (DMP), is currently investigated within clinical studies, however 200 ns pulse durations are under investigation. Transient micro bubbles in the retinal pigment epithelium (RPE) are expected to be the origin of cell damage due to irradiation with laser pulses shorter than 50 μs. The bubbles emerge at the strongly absorbing RPE melanosomes. Cell membrane disruption caused by the transient associated volume increase is expected to be the origin of the angiographically observed RPE leakage. We investigate micro bubble formation and dynamics in porcine RPE using pulse durations of 150 ns. A laser interferometry system at 830 nm with the aim of an online dosimetry control for SRT was developed. Bubble formation was detected interferometrically and by fast flash photography. A correlation to cell damage observed with a vitality stain is found. A bubble detection algorithm is presented.},
       url = {http://dx.doi.org/10.1117/12.728344},
       type = {Conference Proceedings}
    }
    
  • Fritz, A and Ptaszynski, L and Stoehr, H and Brinkmann, R: Dynamic of laser induced transient microbubble clusters. Proc SPIE,
    BibTeX
    @inproceedings{Fritz2009,
       author = {Fritz, A and Ptaszynski, L and Stoehr, H and Brinkmann, R},
       title = {Dynamic of laser induced transient microbubble clusters},
       editor = {(BiOS), Conference on Biomedical Optics},
       publisher = {Proc SPIE},
       type = {Conference Proceedings}
    }
    
  • Lankenau, E. and Schumacher, M. and Koch, P. and König, F. and Daniltchenko, D. and Schmorr, D. and Hüttmann, G.: Dispersion compensation for proximal scanning rigid OCT endoscopes. in SPIE Proc., no. 5316, pp. 172-177,
    BibTeX
    @inproceedings{Lankenau,
       author = {Lankenau, E. and Schumacher, M. and Koch, P. and König, F. and Daniltchenko, D. and Schmorr, D. and Hüttmann, G.},
       title = {Dispersion compensation for proximal scanning rigid OCT endoscopes},
       booktitle = {SPIE Proc.},
       volume = {5316},
       pages = {172-177},
    
    }
  • Hagen-Eggert, M. and Hillmann, D. and Koch, P. and Huttmann, G.: Diffusion-sensitive Fourier-domain optical coherence tomography. no. 7889, pp. 78892B, SPIE,
    BibTeX
    @inproceedings{Hagen-Eggert2011,
       author = {Hagen-Eggert, M. and Hillmann, D. and Koch, P. and Huttmann, G.},
       title = {Diffusion-sensitive Fourier-domain optical coherence tomography},
       editor = {James, G. Fujimoto and Joseph, A. Izatt and Valery, V. Tuchin},
       publisher = {SPIE},
       volume = {7889},
       pages = {78892B},
    
    }
  • Hagen-Eggert, M. and Hillmann, D. and Koch, P. and Huttmann, G.: Diffusion-sensitive Fourier-domain optical coherence tomography. no. 7889, pp. 78892B, SPIE,
    BibTeX
    @inproceedings{Hagen-Eggert2011,
       author = {Hagen-Eggert, M. and Hillmann, D. and Koch, P. and Huttmann, G.},
       title = {Diffusion-sensitive Fourier-domain optical coherence tomography},
       editor = {James, G. Fujimoto and Joseph, A. Izatt and Valery, V. Tuchin},
       publisher = {SPIE},
       volume = {7889},
       pages = {78892B},
    
    }
  • Wurster, Lara M and Warger, W C and Gora, M J and Carruth, R and Tearny, G J and Birngruber, Reginald: Design and development of a miniaturized scanning probe. in Studierendentagung, Universität zu Lübeck,
    BibTeX
    @inproceedings{Wurster2013,
       author = {Wurster, Lara M and Warger, W C and Gora, M J and Carruth, R and Tearny, G J and Birngruber, Reginald},
       title = {Design and development of a miniaturized scanning probe},
       booktitle = {Studierendentagung},
       publisher = {Universität zu Lübeck},
       type = {Conference Proceedings}
    }
    
  • Langejürgen, J and Schlott, K and Bever, M and Hausmann, K and Koinzer, S and Ptaszynski, L and Roider, J and Birngruber, R and Brinkmann, R: Dependence of optoacoustic transients on exciting laser parameters for real-time monitoring of retinal photocoagulation. pp. 73730K-73730K,
    BibTeX Link
    @inproceedings{Langejürgen2009,
       author = {Langejürgen, J and Schlott, K and Bever, M and Hausmann, K and Koinzer, S and Ptaszynski, L and Roider, J and Birngruber, R and Brinkmann, R},
       title = {Dependence of optoacoustic transients on exciting laser parameters for real-time monitoring of retinal photocoagulation},
       pages = {73730K-73730K},
       note = {10.1117/12.831913},
       abstract = {The extent of retinal laser coagulations depends on the temperature increase at the fundus and the time of irradiation. Due to light scattering within the eye and variable fundus pigmentation the induced temperature increase and therefore the extent of the coagulations cannot be predicted solely from the laser parameters. We use optoacoustics to monitor the temperature rise in real-time in vivo (rabbit) and ex vivo (porcine eye) and to automatically control the coagulation strength. Continuous wave treatment laser radiation and pulsed probe laser light (1-1100 ns) are coupled into the same fibre and are imaged onto the retina by a laser slit lamp. The temperature dependent pressure waves are detected by an ultrasonic transducer embedded in a customary contact lens. Below the coagulation threshold the increase in acoustic amplitude due to thermal tissue expansion is up to 40 %. Best signal to noise ratios > 10 are achieved with probe pulse durations of 1 to 75 ns. Further a time critical algorithm is developed which automatically ceases laser treatment when a certain preset coagulation strength is achieved. Coagulations with similar extent are obtained with this method in vitro and in vivo even when varying the power of the treatment laser by 50 %. These preliminary results are very promising, thus this method might be suitable for an automatic feedback controlled photocoagulation with adjustable coagulation strength.},
    url = {http://dx.doi.org/10.1117/12.831913},
       type = {Conference Proceedings}
    }
    
  • Lange, Bjoern I. and Radt, Benno and Huettmann, Gereon: Cr,Tm,Ho: YAG laser amplifier. no. 4267, pp. 169-174, SPIE,
    BibTeX
    @inproceedings{Lange,
       author = {Lange, Bjoern I. and Radt, Benno and Huettmann, Gereon},
       title = {Cr,Tm,Ho: YAG laser amplifier},
       editor = {Richard, Scheps},
       publisher = {SPIE},
       volume = {4267},
       pages = {169-174},
    }
    
  • Brinkmann, Ralf and Kampmeier, Juergen and Grotehusmann, Ulf and Vogel, Alfred and Koop, Norbert and Asiyo-Vogel, Mary and Birngruber, Reginald: Corneal collagen denaturation in laser thermokeratoplasty. no. 2681, pp. 56-63,
    BibTeX Link
    @inproceedings{Brinkmann1996,
       author = {Brinkmann, Ralf and Kampmeier, Juergen and Grotehusmann, Ulf and Vogel, Alfred and Koop, Norbert and Asiyo-Vogel, Mary and Birngruber, Reginald},
       title = {Corneal collagen denaturation in laser thermokeratoplasty},
       volume = {2681},
       pages = {56-63},
       note = {10.1117/12.239611},
       abstract = {In laserthermokeratoplasty (LTK) thermal denaturation and shrinkage of corneal collagen is used to correct hyperopia and astigmatism. In order to optimize dosimetry, the temperature at which maximal shrinkage of collagen fibrils occurs is of major interest. Since the exposure time in clinical LTK-treatment is limited to a few seconds, the kinetics of collagen denaturation as a rate process has to be considered, thus the time of exposure is of critical importance for threshold and shrinkage temperatures. We investigated the time-temperature correlation for corneal collagen denaturation within different time domains by turbidimetry of scattered HeNe laser probe light using a temperature controlled water bath and pulsed IR laser irradiation. In the temperature range of 60 degree(s)C to 95 degree(s)C we found an exponential relation between the denaturation time and temperature. For the typical LTK-treatment time of 2 s, a temperature of 95 degree(s)C is needed to induce thermal damage. Use of pulsed Holmium laser radiation gave significant scattering of HeNe laser probe light at calculated temperatures of around 100 degree(s)DC. Rate parameters according to the formalism of Arrhenius were fitted to these results. Force measurements showed the simultaneous onset of light scattering and collagen shrinkage.},
       url = {http://dx.doi.org/10.1117/12.239611},
       type = {Conference Proceedings}
    }
    
  • Steven, Philip and Koop, Norbert and Huttmann, Gereon: Confocal microscopy versus two-photon microscopy: imaging of ocular surface pathologies. no. 6860, pp. 686023, SPIE,
    BibTeX
    @inproceedings{Steven,
       author = {Steven, Philip and Koop, Norbert and Huttmann, Gereon},
       title = {Confocal microscopy versus two-photon microscopy: imaging of ocular surface pathologies},
       editor = {Ammasi, Periasamy and Peter, T. C. So},
       publisher = {SPIE},
       volume = {6860},
       pages = {686023},
    
    }
  • Just, T. and Wiechmann, T. and Stachs, O. and Stave, J. and Guthoff, R. and Huttmann, G. and Pau, H. W.: Confocal endomicroscopy of the larynx. no. 8207, pp. 82072H, SPIE,
    BibTeX
    @inproceedings{Just,
       author = {Just, T. and Wiechmann, T. and Stachs, O. and Stave, J. and Guthoff, R. and Huttmann, G. and Pau, H. W.},
       title = {Confocal endomicroscopy of the larynx},
       editor = {Nikiforos, Kollias and Bernard, Choi and Haishan, Zeng and Hyun Wook, Kang and Bodo, E. Knudsen and Brian Jet-Fei, Wong and Justus, F. Ilgner and Krzysztof, Izdebski and Melissa, J. Suter and Stephen, Lam and Matthew, Brenner and Kenton, W. Gregory and Guillermo, J. Tearney and Laura, Marcu and Henry, Hirschberg and Steen, Madsen and Anita, Mahadevan-Jansen and Jansen, E. Duco and Andreas, Mandelis},
       publisher = {SPIE},
       volume = {8207},
       pages = {82072H},
    
    }
  • Bonin, Tim and Koch, Peter and Huttmann, Gereon: Comparison of fast swept source full-field OCT with conventional scanning OCT. no. 8091, pp. 80911K, SPIE,
    BibTeX
    @inproceedings{Bonin2011,
       author = {Bonin, Tim and Koch, Peter and Huttmann, Gereon},
       title = {Comparison of fast swept source full-field OCT with conventional scanning OCT},
       editor = {Rainer, A. Leitgeb and Brett, E. Bouma},
       publisher = {SPIE},
       volume = {8091},
       pages = {80911K},
    
    }
  • Rohde, Ingo and Masch, Jennifer- M. and Theisen-Kunde, Dirk and Marczynski-Bühlow, Martin and Lutter, Georg and Brinkmann, Ralf: Cardiovascular damage after cw and Q-switched 2μm laser irradiation. no. 8803, pp. 88030I-88030I-6,
    BibTeX Link
    @inproceedings{Rohde2013,
       author = {Rohde, Ingo and Masch, Jennifer- M. and Theisen-Kunde, Dirk and Marczynski-Bühlow, Martin and Lutter, Georg and Brinkmann, Ralf},
       title = {Cardiovascular damage after cw and Q-switched 2μm laser irradiation},
       volume = {8803},
       pages = {88030I-88030I-6},
       note = {10.1117/12.2033550},
       abstract = {Aiming for laser-assisted resection of calcified aortic valve structures for Transcatheter Aortic Valve Implantation (TAVI), a Q-switched Tm:YAG laser emitting at a wavelength of 2.01 μm was used to evaluate the cutting efficiency on highly calcified human aortic leaflets in-vitro. The calcified aortic leaflets were examined regarding ablation rates and debris generation, using a pulse energy of 4.3 mJ, a pulse duration of 0.8-1 μs and a repetition rate of 1 kHz. The radiation was transmitted via a 200 μm core diameter quartz fiber. Resection was performed in a fiber-tissue contact mode on water-covered samples in a dish. The remnant particles were analyzed with respect to quantity and size by light microscopy. Additionally, soft tissue of porcine aortic vessels was examined for histologically detectable thermo-mechanical damage after continuous wave and Q-switched 2μm laser irradiation. An ablation rate of 36.7 ± 25.3 mg/min could be realised on highly calcified aortic leaflets, with 85.4% of the remnant particles being <6 μm in diameter. The maximum damaged area of the soft tissue was < 1 mm for both, cw and pulsed laser irradiation. This limits the expected collateral damage of healthy tissue during the medical procedure. Overall, the Q-switched Tm:YAG laser system showed promising results in cutting calcified aortic valves, transmitting sufficient energy through a small flexible fibre.},
       url = {http://dx.doi.org/10.1117/12.2033550},
       type = {Conference Proceedings}
    }
    
  • Seifert, Eric and Roh, Young-Jung and Fritz, Andreas and Park, Young Gun and Kang, Seungbum and Theisen-Kunde, Dirk and Brinkmann, Ralf: Automatic irradiation control by an optical feedback technique for selective retina treatment (SRT) in a rabbit model. no. 8803, pp. 880303-880303-6,
    BibTeX Link
    @inproceedings{Seifert2013,
       author = {Seifert, Eric and Roh, Young-Jung and Fritz, Andreas and Park, Young Gun and Kang, Seungbum and Theisen-Kunde, Dirk and Brinkmann, Ralf},
       title = {Automatic irradiation control by an optical feedback technique for selective retina treatment (SRT) in a rabbit model},
       volume = {8803},
       pages = {880303-880303-6},
       note = {10.1117/12.2033560},
       abstract = {Selective Retina Therapy (SRT) targets the Retinal Pigment Epithelium (RPE) without effecting neighboring layers as the photoreceptors or the choroid. SRT related RPE defects are ophthalmoscopically invisible. Owing to this invisibility and the variation of the threshold radiant exposure for RPE damage the treating physician does not know whether the treatment was successful or not. Thus measurement techniques enabling a correct dosing are a demanded element in SRT devices. The acquired signal can be used for monitoring or automatic irradiation control. Existing monitoring techniques are based on the detection of micro-bubbles. These bubbles are the origin of RPE cell damage for pulse durations in the ns and μs time regime 5μs. The detection can be performed by optical or acoustical approaches. Monitoring based on an acoustical approach has already been used to study the beneficial effects of SRT on diabetic macula edema and central serous retinopathy. We have developed a first real time feedback technique able to detect micro-bubble induced characteristics in the backscattered laser light fast enough to cease the laser irradiation within a burst. Therefore the laser energy within a burst of at most 30 pulses is increased linearly with every pulse. The laser irradiation is ceased as soon as micro-bubbles are detected. With this automatic approach it was possible to observe invisible lesions, an intact photoreceptor layer and a reconstruction of the RPE within one week.},
       url = {http://dx.doi.org/10.1117/12.2033560},
       type = {Conference Proceedings}
    }
    
  • Godwin, Robert P. and Chapyak, Edward J. and Noack, J. and Vogel, A.: Aspherical bubble dynamics and oscillation times. pp. CTuC3, Optical Society of America,
    BibTeX
    @inproceedings{Godwin,
       author = {Godwin, Robert P. and Chapyak, Edward J. and Noack, J. and Vogel, A.},
       title = {Aspherical bubble dynamics and oscillation times},
       series = {OSA Technical Digest},
       publisher = {Optical Society of America},
       pages = {CTuC3},
    }
    
  • Miura, Y and Huettmann, G and Orzekowsky-Schroeder, R and Steven, P and Szaszák, M and Koop, N and Brinkmann, R: Appearance of autofluorescence in RPE cells at the rim of photocoagulation. in FLIM 2010 - Symposium Fluorescence Lifetime Imaging of the Human Retina,
    BibTeX
    @inproceedings{Miura2010,
       author = {Miura, Y and Huettmann, G and Orzekowsky-Schroeder, R and Steven, P and Szaszák, M and Koop, N and Brinkmann, R},
       title = {Appearance of autofluorescence in RPE cells at the rim of photocoagulation},
       booktitle = {FLIM 2010 - Symposium "Fluorescence Lifetime Imaging of the Human Retina"},
       type = {Conference Proceedings}
    }
    
    
    
  • Hagen-Eggert, M. and Koch, P. and Huttmann, G.: Analysis of the signal fall-off in spectral domain optical coherence tomography systems. no. 8213, pp. 82131K, SPIE,
    BibTeX
    @inproceedings{Hagen-Eggert,
       author = {Hagen-Eggert, M. and Koch, P. and Huttmann, G.},
       title = {Analysis of the signal fall-off in spectral domain optical coherence tomography systems},
       editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
       publisher = {SPIE},
       volume = {8213},
       pages = {82131K},
    
    }
    
  • Just, T. and Lankenau, E. and Huttmann, G. and Pau, H. W.: An optical coherence tomography study for imaging the round window niche and the promontorium tympani. no. 7548, pp. 754833, SPIE,
    BibTeX
    @inproceedings{Just,
       author = {Just, T. and Lankenau, E. and Huttmann, G. and Pau, H. W.},
       title = {An optical coherence tomography study for imaging the round window niche and the promontorium tympani},
       editor = {Nikiforos, Kollias and Bernard, Choi and Haishan, Zeng and Reza, S. Malek and Brian, J. Wong and Justus, F. R. Ilgner and Kenton, W. Gregory and Guillermo, J. Tearney and Laura, Marcu and Henry, Hirschberg and Steen, J. Madsen and Andreas, Mandelis and Anita, Mahadevan-Jansen and Jansen, E. Duco},
       publisher = {SPIE},
       volume = {7548},
       pages = {754833},
    
    }
  • Just, T. and Lankenau, E. and Huttmann, G. and Pau, H. W.: An optical coherence tomography study for imaging the round window niche and the promontorium tympani. no. 7548, pp. 754833, SPIE,
    BibTeX
    @inproceedings{Just,
       author = {Just, T. and Lankenau, E. and Huttmann, G. and Pau, H. W.},
       title = {An optical coherence tomography study for imaging the round window niche and the promontorium tympani},
       editor = {Nikiforos, Kollias and Bernard, Choi and Haishan, Zeng and Reza, S. Malek and Brian, J. Wong and Justus, F. R. Ilgner and Kenton, W. Gregory and Guillermo, J. Tearney and Laura, Marcu and Henry, Hirschberg and Steen, J. Madsen and Andreas, Mandelis and Anita, Mahadevan-Jansen and Jansen, E. Duco},
       publisher = {SPIE},
       volume = {7548},
       pages = {754833},
    
    }
  • Sudkamp, Helge and Lee, H Y and Hüttmann, Gereon and Kellerbee, A K: An approach to increase the speed of Optical Coherence Tomography using a Virtually Imaged Phased Array. in Studierendentagung, Universität zu Lübeck,
    BibTeX
    @inproceedings{Sudkamp2013,
       author = {Sudkamp, Helge and Lee, H Y and Hüttmann, Gereon and Kellerbee, A K},
       title = {An approach to increase the speed of Optical Coherence Tomography using a Virtually Imaged Phased Array},
       booktitle = {Studierendentagung},
       publisher = {Universität zu Lübeck},
       type = {Conference Proceedings}
    
  • Nahen, Kester and Vogel, Alfred: Acoustic spectroscopy of Er: YAG laser ablation of skin: first results. in BiOS`98 International Biomedical Optics Symposium, pp. 218-229, International Society for Optics and Photonics,
    BibTeX
    @inproceedings{Nahen1998,
       author = {Nahen, Kester and Vogel, Alfred},
       title = {Acoustic spectroscopy of Er: YAG laser ablation of skin: first results},
       booktitle = {BiOS'98 International Biomedical Optics Symposium},
       publisher = {International Society for Optics and Photonics},
       pages = {218-229},
       type = {Conference Proceedings}
    }
    
  • Nahen, Kester and Vogel, Alfred: Acoustic signal characteristics during IR laser ablation and their consequences for acoustic tissue discrimination. in BiOS 2000 The International Symposium on Biomedical Optics, pp. 166-176, International Society for Optics and Photonics,
    BibTeX
    @inproceedings{Nahen2000,
       author = {Nahen, Kester and Vogel, Alfred},
       title = {Acoustic signal characteristics during IR laser ablation and their consequences for acoustic tissue discrimination},
       booktitle = {BiOS 2000 The International Symposium on Biomedical Optics},
       publisher = {International Society for Optics and Photonics},
       pages = {166-176},
       type = {Conference Proceedings}
    }
    
  • Baade, Alexander and Schlott, Kerstin and Birngruber, Reginald and Brinkmann, Ralf: A numerical model for heat and pressure propagation for temperature controlled retinal photocoagulation. no. 8803, pp. 88030O-88030O-9,
    BibTeX Link
    @inproceedings{Baade2013,
       author = {Baade, Alexander and Schlott, Kerstin and Birngruber, Reginald and Brinkmann, Ralf},
       title = {A numerical model for heat and pressure propagation for temperature controlled retinal photocoagulation},
       volume = {8803},
       pages = {88030O-88030O-9},
       note = {10.1117/12.2033590},
       abstract = {Retinal photocoagulation is an established treatment for various retinal diseases. The temperature development during a treatment can be monitored by applying short laser pulses in addition to the treatment laser light. The laser pulses induce thermoelastic pressure waves that can be detected at the cornea. We present a numerical model to examine the temperature development during the treatment as well as the formation and propagation of the ultrasonic waves. Using the model, it is possible to determine the peak temperature during retinal photocoagulation from the measured signal, and investigate the behaviour of the temperature profile and the accuracy of the temperature determination under varying conditions such as inhomogeneous pigmentation or change in irradiation parameters. It was shown that there is an uncertainty of 2.5 -9% in the determination of the peak temperature when the absorption coefficient between the absorbing layers is varied by a factor of 2. Furthermore the model was extended in order to incorporate the photoacoustic pressure generation and wave propagation. It was shown that for an irradiation pulse duration of 75 ns the resulting pressure wave energy is attenuated by 76 % due to frequency dependent attenuation in water.},
       url = {http://dx.doi.org/10.1117/12.2033590},
       type = {Conference Proceedings}
    }