2013
Tianshi
Wang,
Wolfgang
Wieser,
Geert
Springeling,
Robert
Beurskens,
Charles T.
Lancee,
Tom
Pfeiffer,
Antonius F. W.
van der Steen,
Robert
Huber, and
Gijs
van Soest,
Ultrahigh-speed intravascular optical coherence tomography imaging at 3200 frames per second, in Optical Coherence Tomography and Coherence Techniques VI , Brett E. Bouma and Rainer A. Leitgeb, Eds. SPIE, Jun.2013. pp. 88020O.
Ultrahigh-speed intravascular optical coherence tomography imaging at 3200 frames per second, in Optical Coherence Tomography and Coherence Techniques VI , Brett E. Bouma and Rainer A. Leitgeb, Eds. SPIE, Jun.2013. pp. 88020O.
| DOI: | 10.1117/12.2032723 |
| Bibtex: | @inproceedings{10.1117/12.2032723,
author = {Tianshi Wang and Wolfgang Wieser and Geert Springeling and Robert Beurskens and Charles T. Lancee and Tom Pfeiffer and Antonius F. W. van der Steen and Robert Huber and Gijs van Soest},
title = {{Ultrahigh-speed intravascular optical coherence tomography imaging at 3200 frames per second}},
volume = {8802},
booktitle = {Optical Coherence Tomography and Coherence Techniques VI},
editor = {Brett E. Bouma and Rainer A. Leitgeb},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {88020O},
abstract = {We demonstrated intravascular OCT imaging with frame rate up to 3.2 kHz (192,000 rpm scanning). This was achieved by
using a custom-built catheter in which the circumferential scanning was actuated by a 1.0 mm diameter synchronous
motor. The OCT system was based on a Fourier Domain Mode Locked laser operating at an A-line rate of 1.6 MHz. The
diameter of the catheter was 1.1 mm at the tip. Ex vivo images of human coronary artery (~78.4 mm length) were acquired
at a pullback speed of 100 mm/s. True 3D volumetric imaging of the entire artery, with adequate sampling in all
dimensions, was performed in < 1 second acquisition time.},
year = {2013},
doi = {10.1117/12.2032723},
URL = {https://doi.org/10.1117/12.2032723}
}
|
Christoph M.
Eigenwillig,
Sebastian
Todor,
Wolfgang
Wieser,
Benjamin R.
Biedermann,
Thomas
Klein,
Christian
Jirauschek, and
Robert
Huber,
Picosecond pulses from a Fourier domain mode locked (FDML) laser, in 2013 Conference on Lasers & Electro-Optics Europe & International Quantum Electronics Conference CLEO EUROPE/IQEC , Mai2013. pp. 1.
Picosecond pulses from a Fourier domain mode locked (FDML) laser, in 2013 Conference on Lasers & Electro-Optics Europe & International Quantum Electronics Conference CLEO EUROPE/IQEC , Mai2013. pp. 1.
| DOI: | 10.1109/CLEOE-IQEC.2013.6801076 |
| Bibtex: | @INPROCEEDINGS{6801076,
author={Eigenwillig, Christoph M. and Todor, Sebastian and Wieser, Wolfgang and Biedermann, Benjamin R. and Klein, Thomas and Jirauschek, Christian and Huber, Robert},
booktitle={2013 Conference on Lasers & Electro-Optics Europe & International Quantum Electronics Conference CLEO EUROPE/IQEC},
title={Picosecond pulses from a Fourier domain mode locked (FDML) laser},
year={2013},
volume={},
number={},
pages={1-1},
doi={10.1109/CLEOE-IQEC.2013.6801076}} |
2012
Thomas
Klein,
Wolfgang
Wieser,
Raphael
André,
Tom
Pfeiffer,
Christoph M.
Eigenwillig, and
Robert
Huber,
Multi-MHz FDML OCT: snapshot retinal imaging at 6.7 million axial-scans per second, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI , Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin, Eds. SPIE, Feb.2012. pp. 82131E.
Multi-MHz FDML OCT: snapshot retinal imaging at 6.7 million axial-scans per second, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI , Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin, Eds. SPIE, Feb.2012. pp. 82131E.
| DOI: | 10.1117/12.908798 |
| Bibtex: | @inproceedings{10.1117/12.908798,
author = {Thomas Klein and Wolfgang Wieser and Raphael Andr{\'e} and Tom Pfeiffer and Christoph M. Eigenwillig and Robert Huber},
title = {{Multi-MHz FDML OCT: snapshot retinal imaging at 6.7 million axial-scans per second}},
volume = {8213},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI},
editor = {Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82131E},
abstract = {We demonstrate the acquisition of densely sampled wide-field 3D OCT datasets of the human retina in 0.3s. This
performance is achieved with a multi-MHz Fourier domain mode-locked (FDML) laser source operating at 1050nm. A two-beam
setup doubles the 3.35MHz laser sweep rate to 6.7MHz, which is 16x faster than results achieved with any non-FDML
source used for retinal OCT. We discuss two main benefits of these high line rates: First, large datasets over an ultra-wide
field of view can be acquired with a low probability of distortions. Second, even if eye movements occur, now the scan rate
is high enough to directly correct even the fastest saccades without loss of information.},
keywords = {Optical coherence tomography, OCT, MHz OCT, Fourier-domain mode-locking, FDML, retinal imaging},
year = {2012},
doi = {10.1117/12.908798},
URL = {https://doi.org/10.1117/12.908798}
}
|
Sebastian
Marschall,
Teresa
Torzicky,
Thomas
Klein,
Wolfgang
Wieser,
Michael
Pircher,
Erich
Götzinger,
Stefan
Zotter,
Marco
Bonesi,
Benjamin R.
Biedermann,
Christian
Pedersen,
Robert
Huber,
Christoph K.
Hitzenberger, and
Peter E.
Andersen,
High-speed polarization-sensitive OCT at 1060 nm using a Fourier domain mode-locked swept source, in Biophotonics: Photonic Solutions for Better Health Care III , Jürgen Popp and Wolfgang Drexler and Valery V. Tuchin and Dennis L. Matthews, Eds. SPIE, Mai2012. pp. 84271D.
High-speed polarization-sensitive OCT at 1060 nm using a Fourier domain mode-locked swept source, in Biophotonics: Photonic Solutions for Better Health Care III , Jürgen Popp and Wolfgang Drexler and Valery V. Tuchin and Dennis L. Matthews, Eds. SPIE, Mai2012. pp. 84271D.
| DOI: | 10.1117/12.922313 |
| Bibtex: | @inproceedings{10.1117/12.922313,
author = {Sebastian Marschall and Teresa Torzicky and Thomas Klein and Wolfgang Wieser and Michael Pircher and Erich G{\"o}tzinger and Stefan Zotter and Marco Bonesi and Benjamin Biedermann and Christian Pedersen and Robert Huber and Christoph Hitzenberger and Peter Andersen},
title = {{High-speed polarization-sensitive OCT at 1060 nm using a Fourier domain mode-locked swept source}},
volume = {8427},
booktitle = {Biophotonics: Photonic Solutions for Better Health Care III},
editor = {J{\"u}rgen Popp and Wolfgang Drexler and Valery V. Tuchin and Dennis L. Matthews},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {84271D},
abstract = {Optical coherence tomography (OCT) in the 1060nm range is interesting for in vivo imaging of the human
posterior eye segment (retina, choroid, sclera), as it permits a long penetration depth. Complementary to
structural images, polarization-sensitive OCT (PS-OCT) images visualize birefringent, polarization-maintaining
or depolarizing areas within the sample. This information can be used to distinguish retinal layers and structures
with different polarization properties. High imaging speed is crucial for imaging ocular structures in vivo in order
to minimize motion artifacts while acquiring sufficiently large datasets. Here, we demonstrate PS-OCT imaging
at 350 kHz A-scan rate using a two-channel PS-OCT system in conjunction with a Fourier domain mode-locked
laser. The light source spectrum spans up to 100nm around the water absorption minimum at 1060 nm. By
modulating the laser pump current, we can optimize the spectrum and achieve a depth resolution of 9 μm in air
(6.5 μm in tissue). We acquired retinal images in vivo with high resolution and deep penetration into choroid and
sclera, and features like the depolarizing RPE or an increasing phase retardation at the chorio-scleral interface
are clearly visualized.},
keywords = {optical coherence tomography, polarization-sensitive OCT, swept source, Fourier domain mode-locking, 1060 nm},
year = {2012},
doi = {10.1117/12.922313},
URL = {https://doi.org/10.1117/12.922313}
}
|
Wolfgang
Wieser,
Thomas
Klein,
Desmond C.
Adler,
Francois
Trepanier,
Sebastian
Karpf,
Christoph M.
Eigenwillig,
Joseph M.
Schmitt, and
Robert
Huber,
Dispersion Compensated Megahertz FDML Laser for Imaging of the Anterior Segment, in Conference on Lasers and Electro-Optics 2012 , Optica Publishing Group, Mai2012. pp. JTh3J.2.
Dispersion Compensated Megahertz FDML Laser for Imaging of the Anterior Segment, in Conference on Lasers and Electro-Optics 2012 , Optica Publishing Group, Mai2012. pp. JTh3J.2.
| DOI: | 10.1364/CLEO_AT.2012.JTh3J.2 |
| Bibtex: | @inproceedings{Wieser:12,
author = {Wolfgang Wieser and Thomas Klein and Desmond C. Adler and Francois Tr\'{e}panier and Sebastian Karpf and Christoph M Eigenwillig and Joseph M. Schmitt and Robert Huber},
booktitle = {Conference on Lasers and Electro-Optics 2012},
journal = {Conference on Lasers and Electro-Optics 2012},
keywords = {Optical coherence tomography; Lasers, tunable; Optical coherence tomography; Fiber Bragg gratings; Fourier domain mode locking; Image quality; Laser modes; Mode locking; Optical coherence tomography},
pages = {JTh3J.2},
publisher = {Optica Publishing Group},
title = {Dispersion Compensated Megahertz FDML Laser for Imaging of the Anterior Segment},
year = {2012},
url = {https://opg.optica.org/abstract.cfm?URI=CLEO_AT-2012-JTh3J.2},
doi = {10.1364/CLEO_AT.2012.JTh3J.2},
abstract = {We present a Fourier domain mode locked laser at 1.6 MHz scan rate with greatly improved coherence length by reducing the laser cavity dispersion and the application of this laser in optical coherence tomography.},
} |
Cedric
Blatter,
Branislav
Grajciar,
Robert
Huber, and
Rainer
Leitgeb,
Deep skin structural and microcirculation imaging with extended-focus OCT, in Photonic Therapeutics and Diagnostics VIII , SPIE, Feb.2012. pp. 82070B.
Deep skin structural and microcirculation imaging with extended-focus OCT, in Photonic Therapeutics and Diagnostics VIII , SPIE, Feb.2012. pp. 82070B.
| DOI: | 10.1117/12.909830 |
| Bibtex: | @inproceedings{10.1117/12.909830,
author = {Cedric Blatter and Branislav Grajciar and Robert Huber and Rainer A. Leitgeb},
title = {{Deep skin structural and microcirculation imaging with extended-focus OCT}},
volume = {8207},
booktitle = {Photonic Therapeutics and Diagnostics VIII},
editor = {Anita Mahadevan-Jansen and E. Duco Jansen and Andreas Mandelis and Kenton W. Gregory M.D. and Guillermo J. Tearney M.D. and Laura Marcu and Nikiforos Kollias and Bernard Choi and Haishan Zeng and Melissa J. Suter and Stephen Lam and Matthew Brenner and Hyun Wook Kang and Bodo E. Knudsen M.D. and Henry Hirschberg M.D. and Steen Madsen and Brian Jet-Fei Wong M.D. and Justus F. Ilgner M.D. and Krzysztof Izdebski},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82070B},
abstract = {We present an extended focus OCT system for dermatologic applications that maintains high lateral resolution over a
large depth range by using Bessel beam illumination. More, Bessel beams exhibit a self-reconstruction property that is
particularly useful to avoid shadowing from surface structures such as hairs. High lateral resolution and high-speed
measurement, thanks to a rapidly tuning swept source, allows not only for imaging of small skin structures in depth but
also for comprehensive visualization of the small capillary network within the human skin in-vivo. We use this
information for studying temporal vaso-responses to hypothermia. In contrast to other perfusion imaging methods such
as laser Doppler imaging (LDI), OCT gives specific access to vascular responses in different vascular beds in depth.},
keywords = {Optical Coherence Tomography, FDML Swept Source, Extended focus, Bessel beam, Self-reconstruction property, Microcirculation imaging, Vasomechanics},
year = {2012},
doi = {10.1117/12.909830},
URL = {https://doi.org/10.1117/12.909830}
}
|
Desmond C.
Adler,
Wolfgang
Wieser,
Francois
Trepanier,
Joseph M.
Schmitt, and
Robert
Huber,
Coherence length extension of Fourier domain mode locked lasers, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI , Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin, Eds. SPIE, Feb.2012. pp. 82130O.
Coherence length extension of Fourier domain mode locked lasers, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI , Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin, Eds. SPIE, Feb.2012. pp. 82130O.
| DOI: | 10.1117/12.908148 |
| Bibtex: | @inproceedings{10.1117/12.908148,
author = {Desmond C. Adler and Wolfgang Wieser and Francois Trepanier and Joseph M. Schmitt and Robert A. Huber},
title = {{Coherence length extension of Fourier domain mode locked lasers}},
volume = {8213},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI},
editor = {Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82130O},
abstract = {Fourier domain mode locked (FDML) lasers provide high sweep rates, broad tuning ranges, and high output powers for
optical coherence tomography (OCT) systems. However, presently-known FDML lasers at 1300 nm have relatively
short coherence lengths, limiting the size of samples that can be imaged. Furthermore, FDML lasers produce only one
useable sweep direction. We report FDML coherence length extension by incorporating advanced dispersion
compensation modules (DCMs). DCMs eliminate group velocity dispersion in the cavity, doubling coherence lengths
and ensuring uniform axial resolution over the imaging range. Additionally, forward and backward sweeps are nearly
identical, removing the need for external buffering stages.},
keywords = {Fourier domain mode locked lasers, FDML, swept source, optical coherence tomography, dispersion compensation},
year = {2012},
doi = {10.1117/12.908148},
URL = {https://doi.org/10.1117/12.908148}
}
|
Sebastian
Marschall,
Thomas
Klein,
Wolfgang
Wieser,
Teresa
Torzicky,
Michael
Pircher,
Benjamin R.
Biedermann,
Christian
Pedersen,
Christoph K.
Hitzenberger,
Robert
Huber, and
Peter E.
Andersen,
Broadband Fourier domain mode-locked laser for optical coherence tomography at 1060 nm, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI , Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin, Eds. SPIE, Feb.2012. pp. 82130R.
Broadband Fourier domain mode-locked laser for optical coherence tomography at 1060 nm, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI , Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin, Eds. SPIE, Feb.2012. pp. 82130R.
| DOI: | 10.1117/12.906148 |
| Bibtex: | @inproceedings{10.1117/12.906148,
author = {Sebastian Marschall and Thomas Klein and Wolfgang Wieser and Teresa Torzicky and Michael Pircher and Benjamin R. Biedermann and Christian Pedersen and Christoph K. Hitzenberger and Robert Huber and Peter E. Andersen},
title = {{Broadband Fourier domain mode-locked laser for optical coherence tomography at 1060 nm}},
volume = {8213},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI},
editor = {Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82130R},
abstract = {Optical coherence tomography (OCT) in the 1060nm range is interesting for in vivo imaging of the human
posterior eye segment (retina, choroid, sclera) due to low absorption in water and deep penetration into the
tissue. Rapidly tunable light sources, such as Fourier domain mode-locked (FDML) lasers, enable acquisition
of densely sampled three-dimensional datasets covering a wide field of view. However, semiconductor optical
amplifiers (SOAs)-the typical laser gain media for swept sources-for the 1060nm band could until recently
only provide relatively low output power and bandwidth. We have implemented an FDML laser using a new SOA
featuring broad gain bandwidth and high output power. The output spectrum coincides with the wavelength
range of minimal water absorption, making the light source ideal for OCT imaging of the posterior eye segment.
With a moderate SOA current (270 mA) we achieve up to 100nm total sweep range and 12 μm depth resolution
in air. By modulating the current, we can optimize the output spectrum and thereby improve the resolution to
9 μm in air (~6.5 μm in tissue). The average output power is higher than 20mW. Both sweep directions show
similar performance; hence, both can be used for OCT imaging. This enables an A-scan rate of 350 kHz without
buffering the light source output.},
keywords = {optical coherence tomography, tunable laser, swept source, Fourier domain mode-locking, broadband semiconductor optical amplifier},
year = {2012},
doi = {10.1117/12.906148},
URL = {https://doi.org/10.1117/12.906148}
}
|
M.
Hagen-Eggert, and
P.
Koch,
Analysis of the signal fall-off in spectral domain optical coherence tomography systems, in Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series , Feb.2012.
Analysis of the signal fall-off in spectral domain optical coherence tomography systems, in Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series , Feb.2012.
| DOI: | 10.1117/12.910921 |
| Bibtex: | @INPROCEEDINGS{2012SPIE.8213E..23H,
author = {{Hagen-Eggert}, M. and {Koch}, P. and {H{\"u}ttmann}, G.},
title = "{Analysis of the signal fall-off in spectral domain optical coherence tomography systems}",
booktitle = {Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series},
year = 2012,
series = {Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series},
volume = 8213,
month = feb,
doi = {10.1117/12.910921},
adsurl = {http://adsabs.harvard.edu/abs/2012SPIE.8213E..23H},
adsnote = {Provided by the SAO/NASA Astrophysics Data System}
} |
Cedric
Blatter,
Branislav
Grajciar,
Boris
Hermann,
Robert
Huber,
Wolfgang
Drexler, and
Rainer A.
Leitgeb,
Simultaneous dark-bright field swept source OCT for ultrasound detection, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI , Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin, Eds. SPIE, Feb.2012. pp. 82131M.
Simultaneous dark-bright field swept source OCT for ultrasound detection, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI , Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin, Eds. SPIE, Feb.2012. pp. 82131M.
| DOI: | 10.1117/12.911443 |
| Bibtex: | @inproceedings{10.1117/12.911443,
author = {Cedric Blatter and Branislav Grajciar and Boris Hermann and Robert Huber and Wolfgang Drexler and Rainer A. Leitgeb},
title = {{Simultaneous dark-bright field swept source OCT for ultrasound detection}},
volume = {8213},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI},
editor = {Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82131M},
abstract = {We introduce a swept source FDOCT imaging system that allows measuring simultaneously the reflected light and
scattered light (bright field) and the scattered light only (dark field) in two different channels through separate Gaussian
and Bessel detection. Specular reflections can then be used to obtain knowledge about the sample time evolution with
high SNR for phase analysis. Based on this configuration, we provide a proof-of principle study for resolving ultrasound
pulse trains with high temporal resolution on surfaces, which potentially provides a novel phase sensitive all optical
detection scheme for the combination of OCT with photoacoustic imaging.},
keywords = {Dark field imaging, Bessel beam, Extended focus, FDML Swept Source, Multichannel detection, Photoacoustic, Ultrasound, Phase sensitive},
year = {2012},
doi = {10.1117/12.911443},
URL = {https://doi.org/10.1117/12.911443}
}
|
2011
Cedric
Blatter,
Branislav
Grajciar,
Christoph M.
Eigenwillig,
Wolfgang
Wieser,
Benjamin R.
Biedermann,
Robert
Huber, and
Rainer A.
Leitgeb,
High-speed functional OCT with self-reconstructive Bessel illumination at 1300 nm, in Optical Coherence Tomography and Coherence Techniques V , Rainer A. Leitgeb and Brett E. Bouma, Eds. SPIE, Jun.2011. pp. 809104.
High-speed functional OCT with self-reconstructive Bessel illumination at 1300 nm, in Optical Coherence Tomography and Coherence Techniques V , Rainer A. Leitgeb and Brett E. Bouma, Eds. SPIE, Jun.2011. pp. 809104.
| DOI: | 10.1117/12.889669 |
| Bibtex: | @inproceedings{10.1117/12.889669,
author = {Cedric Blatter and Branislav Grajciar and Christoph M. Eigenwillig and Wolfgang Wieser and Benjamin R. Biedermann and Robert Huber and Rainer A. Leitgeb},
title = {{High-speed functional OCT with self-reconstructive Bessel illumination at 1300 nm}},
volume = {8091},
booktitle = {Optical Coherence Tomography and Coherence Techniques V},
editor = {Rainer A. Leitgeb and Brett E. Bouma},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {809104},
abstract = {We present a Bessel beam illumination FDOCT setup with FDML buffered swept source at 1300nm. An extended focus
is achieved due to the Bessel beam that preserves its lateral extend over a large depth range. Decoupling the illumination
from the Gaussian detection improves the sensitivity as compared to double passing the ring filter and enables dark field
imaging. Dark field imaging is useful to avoid strong reflexes from the sample's surface that adversely affect the
sensitivity due to the limited dynamic range of high-speed 8bit acquisition cards. Furthermore, Bessel beams exhibit a
self-reconstruction property that allows imaging even behind obstacles such as hairs on skin.
Densely sampled volumes of skin in-vivo with high lateral resolution are acquired at up to 440kHz A-Scan rate. In
addition the possibility of contrasting capillaries with high sensitivity is shown, using inter-B-scan speckle variance
analysis. High-speed imaging is of crucial importance for imaging small details since sample motion artifacts are
reduced and high sampling can be maintained while increasing the B-Scan rate.},
keywords = {Extended focus, Bessel beam, Self-reconstructive illumination, Dark field imaging, Dermatology, Microcirculation imaging, FDML, Swept Source},
year = {2011},
doi = {10.1117/12.889669},
URL = {https://doi.org/10.1117/12.889669}
}
|
Thomas
Klein,
Wolfgang
Wieser,
Benjamin R.
Biedermann,
Christoph M.
Eigenwillig, and
Robert
Huber,
FDML laser for megahertz retinal OCT imaging, in CLEO:2011 - Laser Applications to Photonic Applications , Optica Publishing Group, Jun.2011. pp. CWB1.
FDML laser for megahertz retinal OCT imaging, in CLEO:2011 - Laser Applications to Photonic Applications , Optica Publishing Group, Jun.2011. pp. CWB1.
| DOI: | 10.1364/CLEO_SI.2011.CWB1 |
| Bibtex: | @inproceedings{Klein:11,
author = {Thomas Klein and Wolfgang Wieser and Benjamin R. Biedermann and Christoph M. Eigenwillig and Robert Huber},
booktitle = {CLEO:2011 - Laser Applications to Photonic Applications},
journal = {CLEO:2011 - Laser Applications to Photonic Applications},
keywords = {Optical coherence tomography; Lasers, tunable; Image quality; Imaging techniques; Laser modes; Medical imaging; Mode locking; Optical coherence tomography},
pages = {CWB1},
publisher = {Optica Publishing Group},
title = {FDML laser for megahertz retinal OCT imaging},
year = {2011},
url = {https://opg.optica.org/abstract.cfm?URI=CLEO_SI-2011-CWB1},
doi = {10.1364/CLEO_SI.2011.CWB1},
abstract = {A novel Fourier-domain mode locked (FDML) laser design is presented, yielding the highest wavelength sweep speed reported so far around 1050nm. This enables retinal imaging over a ~70{\textdegree} ultra-wide field of view.},
} |
Ramtin
Rahmanzadeh,
Florian
Rudnitzki,
Elmar
Endl, and
Tayyaba
Hasan,
Targeted molecular effects through laser-irradiated nanoabsorbers, in Proc. SPIE , Newsrrom, SPIE, Eds. 2011.
Targeted molecular effects through laser-irradiated nanoabsorbers, in Proc. SPIE , Newsrrom, SPIE, Eds. 2011.
| DOI: | 10.1117/2.1201102.003548 |
| Bibtex: | @inproceedings{Hüttmann2011,
author = {Hüttmann, Gereon and Rahmanzadeh, Ramtin and Rudnitzki, Florian and Endl, Elmar and Hasan, Tayyaba},
title = {Targeted molecular effects through laser-irradiated nanoabsorbers},
editor = {Newsrrom, SPIE},
DOI = {10.1117/2.1201102.003548},
type = {Conference Proceedings},
year = { 2011}
}
|
Cedric
Blatter,
Branislav
Grajciar,
Robert
Huber, and
Rainer A.
Leitgeb,
Structural and functional imaging with extended focus dark-field OCT at 1300nm, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV , James G. Fujimoto and Joseph A. Izatt and Valery V. Tuchin, Eds. SPIE, Feb.2011. pp. 78891D.
Structural and functional imaging with extended focus dark-field OCT at 1300nm, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV , James G. Fujimoto and Joseph A. Izatt and Valery V. Tuchin, Eds. SPIE, Feb.2011. pp. 78891D.
| DOI: | 10.1117/12.875594 |
| Bibtex: | @inproceedings{10.1117/12.875594,
author = {Cedric Blatter and Branislav Grajciar and Robert Huber and Rainer A. Leitgeb},
title = {{Structural and functional imaging with extended focus dark-field OCT at 1300nm}},
volume = {7889},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV},
editor = {James G. Fujimoto and Joseph A. Izatt and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {78891D},
abstract = {We present an extended focus FDOCT setup with FDML swept source centered at 1310nm. The illumination, preserving
its lateral extend over a large depth range thanks to the use of a Bessel beam, is decoupled from the Gaussian detection in
order to increase the global sensitivity. The efficient spatial separation enables dark-field imaging. In-vivo measurements
in the skin were performed to demonstrate the gain in lateral resolution while preserving the imaging depth. More, the
calculation of the speckle variance between B-Scans allows a clear visualization of the microvasculature.},
keywords = {Extended focus, Dark Field imaging, Bessel beam, FDML Swept Source, dermatology, microvascularisation imaging},
year = {2011},
doi = {10.1117/12.875594},
URL = {https://doi.org/10.1117/12.875594}
}
|
2010
Sebastian
Marschall,
Thomas
Klein,
Wolfgang
Wieser,
Benjamin R.
Biedermann,
Kevin
Hsu,
Bernd
Sumpf,
Karl-Heinz
Hasler,
Götz
Erbert,
Ole B.
Jensen,
Christian
Pedersen,
Robert
Huber, and
Peter E.
Andersen,
High-power FDML laser for swept source-OCT at 1060 nm, in Biophotonics: Photonic Solutions for Better Health Care II , Jürgen Popp and Wolfgang Drexler and Valery V. Tuchin and Dennis L. Matthews, Eds. SPIE, Mai2010. pp. 77150B.
High-power FDML laser for swept source-OCT at 1060 nm, in Biophotonics: Photonic Solutions for Better Health Care II , Jürgen Popp and Wolfgang Drexler and Valery V. Tuchin and Dennis L. Matthews, Eds. SPIE, Mai2010. pp. 77150B.
| DOI: | 10.1117/12.854238 |
| Bibtex: | @inproceedings{10.1117/12.854238,
author = {Sebastian Marschall and Thomas Klein and Wolfgang Wieser and Benjamin Biedermann and Kevin Hsu and Bernd Sumpf and Karl-Heinz Hasler and G{\"o}tz Erbert and Ole B. Jensen and Christian Pedersen and Robert Huber and Peter E. Andersen},
title = {{High-power FDML laser for swept source-OCT at 1060 nm}},
volume = {7715},
booktitle = {Biophotonics: Photonic Solutions for Better Health Care II},
editor = {J{\"u}rgen Popp and Wolfgang Drexler and Valery V. Tuchin and Dennis L. Matthews},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {77150B},
abstract = {We present a novel frequency-swept light source working at 1060nm that utilizes a tapered amplifier as gain
medium. These devices feature significantly higher saturation power than conventional semiconductor optical
amplifiers and can thus improve the limited output power of swept sources in this wavelength range. We
demonstrate that a tapered amplifier can be integrated into a
fiber-based swept source and allows for high-speed
FDML operation. The developed light source operates at a sweep rate of 116kHz with an effective average
output power in excess of 30mW. With a total sweep range of 70 nm an axial resolution of 15 μm in air (~11μm
in tissue) for OCT applications can be achieved.},
keywords = {optical coherence tomography, swept source, tunable laser, tapered amplifier, fourier domain mode-locking},
year = {2010},
doi = {10.1117/12.854238},
URL = {https://doi.org/10.1117/12.854238}
}
|
Sebastian
Marschall,
Thomas
Klein,
Wolfgang
Wieser,
Benjamin R.
Biedermann,
Kevin
Hsu,
Bernd
Sumpf,
Karl-Heinz
Hasler,
Götz
Erbert,
Ole B.
Jensen,
Christian
Pedersen,
Robert
Huber, and
Peter E.
Andersen,
FDML swept source at 1060 nm using a tapered amplifier, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV , Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin, Eds. International Society for Optics and Photonics, Feb.2010. pp. 75541H.
FDML swept source at 1060 nm using a tapered amplifier, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV , Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin, Eds. International Society for Optics and Photonics, Feb.2010. pp. 75541H.
| DOI: | 10.1117/12.842011 |
| Bibtex: | @inproceedings{10.1117/12.842011,
author = {Sebastian Marschall and Thomas Klein and Wolfgang Wieser and Benjamin Biedermann and Kevin Hsu and Bernd Sumpf and Karl-Heinz Hasler and G{\"o}tz Erbert and Ole B. Jensen and Christian Pedersen and Robert Huber and Peter E. Andersen},
title = {{FDML swept source at 1060 nm using a tapered amplifier}},
volume = {7554},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV},
editor = {Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {75541H},
abstract = {We present a novel frequency-swept light source working at 1060nm that utilizes a tapered amplifier as gain
medium. These devices feature significantly higher saturation power than conventional semiconductor optical
amplifiers and can thus improve the limited output power of swept sources in this wavelength range. We
demonstrate that a tapered amplifier can be integrated into a fiber-based swept source and allows for high-speed
FDML operation. The developed light source operates at a sweep rate of 116kHz with an effective average
output power in excess of 30mW. With a total sweep range of 70 nm an axial resolution of 15 μm in air (~11μm in tissue) for OCT applications can be achieved.},
keywords = {optical coherence tomography, swept source, tunable laser, tapered amplifier, fourier domain mode-locking},
year = {2010},
doi = {10.1117/12.842011},
URL = {https://doi.org/10.1117/12.842011}
}
|
Yoko
Miura,
Regina
Orzekowsky-Schröder,
Norbert
Koop,
Philipp
Steven,
Márta
Szaszák, and
Ralf
Brinkmann,
Appearance of autofluorescence in RPE cells at the rim of photocoagulation, in FLIM 2010 - Symposium "Fluorescence Lifetime Imaging of the Human Retina" , 2010.
Appearance of autofluorescence in RPE cells at the rim of photocoagulation, in FLIM 2010 - Symposium "Fluorescence Lifetime Imaging of the Human Retina" , 2010.
Ramtin
Rahmanzadeh,
Prakash
Rai,
Johannes
Gerdes, and
Tayyaba
Hasan,
Targeted light-inactivation of the Ki-67 protein using theranostic liposomes leads to death of proliferating cells, Samuel, Achilefu and Ramesh, Raghavachari, Eds. SPIE, 2010. pp. 757602.
Targeted light-inactivation of the Ki-67 protein using theranostic liposomes leads to death of proliferating cells, Samuel, Achilefu and Ramesh, Raghavachari, Eds. SPIE, 2010. pp. 757602.
| DOI: | 10.1117/12.843850 |
| Bibtex: | @inproceedings{Rahmanzadeh,
author = {Rahmanzadeh, Ramtin and Rai, Prakash and Gerdes, Johannes and Hasan, Tayyaba},
title = {Targeted light-inactivation of the Ki-67 protein using theranostic liposomes leads to death of proliferating cells},
editor = {Samuel, Achilefu and Ramesh, Raghavachari},
publisher = {SPIE},
volume = {7576},
pages = {757602},
year = {2010},
doi ={10.1117/12.843850},
keywords = {Nanotechnology, Ovarian Cancer, Proliferative Index, Photodynamic Therapy,Antibody}
} |
2009
Gesa
Palte,
Wolfgang
Wieser,
Benjamin R.
Biedermann,
Christoph M.
Eigenwillig, and
Robert
Huber,
Fourier domain mode locked (FDML) lasers for polarization sensitive OCT, in Optical Coherence Tomography and Coherence Techniques IV , Peter E. Andersen and Brett E. Bouma, Eds. SPIE, Jul.2009. pp. 73720M.
Fourier domain mode locked (FDML) lasers for polarization sensitive OCT, in Optical Coherence Tomography and Coherence Techniques IV , Peter E. Andersen and Brett E. Bouma, Eds. SPIE, Jul.2009. pp. 73720M.
| DOI: | 10.1117/12.831835 |
| Bibtex: | @inproceedings{10.1117/12.831835,
author = {Gesa Palte and Wolfgang Wieser and Benjamin R. Biedermann and Christoph M. Eigenwillig and Robert Huber},
title = {{Fourier domain mode locked (FDML) lasers for polarization sensitive OCT}},
volume = {7372},
booktitle = {Optical Coherence Tomography and Coherence Techniques IV},
editor = {Peter E. Andersen and Brett E. Bouma},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {73720M},
abstract = {A Fourier Domain mode-locked (FDML) laser for polarization sensitive optical coherence tomography (OCT) is
presented. The laser generates an alternating sequence of wavelength sweeps with their polarization states 90° separated
on the Poincare sphere.},
keywords = {Lasers, tunable, optical coherence tomography, lasers, imaging systems, polarization, fiber},
year = {2009},
doi = {10.1117/12.831835},
URL = {https://doi.org/10.1117/12.831835}
}
|
Benjamin R.
Biedermann,
Wolfgang
Wieser,
Christoph M.
Eigenwillig,
Thomas
Klein, and
Robert
Huber,
Dispersion, coherence and noise of Fourier Domain Mode Locked (FDML) lasers, in CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference , IEEE, Jun.2009. pp. 1-1.
Dispersion, coherence and noise of Fourier Domain Mode Locked (FDML) lasers, in CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference , IEEE, Jun.2009. pp. 1-1.
| DOI: | 10.1109/CLEOE-EQEC.2009.5192900 |
| Bibtex: | @INPROCEEDINGS{5192900,
author={Biedermann, Benjamin R. and Wieser, Wolfgang and Eigenwillig, Christoph M. and Klein, Thomas and Huber, Robert},
booktitle={CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference},
title={Dispersion, coherence and noise of Fourier Domain Mode Locked (FDML) lasers},
year={2009},
volume={},
number={},
pages={1-1},
abstract={We present a detailed analysis of coherence and noise of the FDML laser, depending on filter drive frequency, detuning and amount of cavity dispersion. The results provide insight into phase and amplitude noise of the laser light itself. We address the following two questions: (1) How much dispersion compensation is necessary for optimum laser performance in FDML for a certain width of the optical band pass filter? (2) How are timing mismatch effects, caused by either detuning of the drive frequency or chromatic dispersion in the cavity of the filter, related to coherence length and noise?},
keywords={},
doi={10.1109/CLEOE-EQEC.2009.5192900},
ISSN={},
month={June},} |
Robert Huber,
Advances in Fourier domain OCT, in 2009 IEEE LEOS Annual Meeting Conference Proceedings , IEEE, Okt.2009. pp. 201-202.
Advances in Fourier domain OCT, in 2009 IEEE LEOS Annual Meeting Conference Proceedings , IEEE, Okt.2009. pp. 201-202.
| DOI: | 10.1109/LEOS.2009.5343314 |
| Bibtex: | @INPROCEEDINGS{5343314,
author={Huber, Robert},
booktitle={2009 IEEE LEOS Annual Meeting Conference Proceedings},
title={Advances in Fourier domain OCT},
year={2009},
volume={},
number={},
pages={201-202},
abstract={In optical coherence tomography, the introduction of so called ldquoFrequency Domainrdquo techniques, i.e. spectrally resolved detection, had a dramatic impact on these biomedical imaging systems. The current status and future developments will be discussed.},
keywords={},
doi={10.1109/LEOS.2009.5343314},
ISSN={1092-8081},
month={Oct},} |
Christoph M.
Eigenwillig,
Benjamin R.
Biedermann,
Wolfgang
Wieser, and
Robert
Huber,
Wavelength swept ASE source, in Optical Coherence Tomography and Coherence Techniques IV , Peter E. Andersen and Brett E. Bouma, Eds. SPIE, Jul.2009. pp. 73720O.
Wavelength swept ASE source, in Optical Coherence Tomography and Coherence Techniques IV , Peter E. Andersen and Brett E. Bouma, Eds. SPIE, Jul.2009. pp. 73720O.
| DOI: | 10.1117/12.831831 |
| Bibtex: | @inproceedings{10.1117/12.831831,
author = {Christoph M. Eigenwillig and Benjamin R. Biedermann and Wolfgang Wieser and Robert Huber},
title = {{Wavelength swept ASE source}},
volume = {7372},
booktitle = {Optical Coherence Tomography and Coherence Techniques IV},
editor = {Peter E. Andersen and Brett E. Bouma},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {73720O},
abstract = {We present a novel wavelength swept light source for Optical Coherence Tomography (OCT). Arbitrary sweep rates up
to 2x170kHz are achieved by phase-shifted control of two optical bandpass-filters to compensate light propagation
effects.},
keywords = {amplified spontaneous emission, tunable lasers, lasers, optical coherence tomography, optical frequency domain imaging},
year = {2009},
doi = {10.1117/12.831831},
URL = {https://doi.org/10.1117/12.831831}
}
|
Karol
Karnowski,
Michalina
Gora,
Bartlomiej
Kaluzny,
Robert
Huber,
Maciej
Szkulmowski,
Andrzej M.
Kowalczyk, and
Maciej
Wojtkowski,
Swept source OCT imaging of human anterior segment at 200 kHz, in Ophthalmic Technologies XIX , Fabrice Manns and Per G. Söderberg and Arthur Ho, Eds. SPIE, Feb.2009. pp. 716308.
Swept source OCT imaging of human anterior segment at 200 kHz, in Ophthalmic Technologies XIX , Fabrice Manns and Per G. Söderberg and Arthur Ho, Eds. SPIE, Feb.2009. pp. 716308.
| DOI: | 10.1117/12.808555 |
| Bibtex: | @inproceedings{10.1117/12.808555,
author = {Karol Karnowski and Michalina Gora and Bartlomiej Kaluzny and Robert Huber and Maciej Szkulmowski and Andrzej Kowalczyk and Maciej Wojtkowski},
title = {{Swept source OCT imaging of human anterior segment at 200 kHz}},
volume = {7163},
booktitle = {Ophthalmic Technologies XIX},
editor = {Fabrice Manns and Per G. S{\"o}derberg and Arthur Ho},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {716308},
abstract = {We present applicability of the high speed swept-source optical coherence tomography for in vivo imaging of the anterior segment of the human eye. Three dimensional imaging of the cornea with reduced motion artifacts is possible by using swept source with Fourier domain mode locking operating at 200kHz with 1300nm central wavelength. High imaging speeds allow for assessment of anterior and posterior corneal topography and generation of thickness and elevation maps.},
keywords = {Optical Coherence Tomography, Fourier domain detection methods, swept source OCT, anterior segment of the eye},
year = {2009},
doi = {10.1117/12.808555},
URL = {https://doi.org/10.1117/12.808555}
}
|
Robert Huber,
State-of-the-art and future of ultrahigh speed OCT, in CLEO/Europe and EQEC 2009 Conference Digest , Optica Publishing Group, Jun.2009. pp. JTuA_3.
State-of-the-art and future of ultrahigh speed OCT, in CLEO/Europe and EQEC 2009 Conference Digest , Optica Publishing Group, Jun.2009. pp. JTuA_3.
| DOI: | 10.1109/CLEOE-EQEC.2009.5191695 |
| Bibtex: | @INPROCEEDINGS{5191695,
author={Huber, Robert},
booktitle={CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference},
title={State-of-the-art and future of ultrahigh speed OCT},
year={2009},
volume={},
number={},
pages={1-1},
abstract={This paper reviews the current status of high speed OCT systems on the different levels of development: commercial, laboratory prototype style and proof of concept type systems. The pro and contra of SD-OCT and SS-OCT are discussed and an analysis of the desired optimum imaging speeds for various applications. SS-OCT systems are used for imaging in highly scattering tissue ~1300 nm, a line rate of 60 MHz was achieved by with SD-OCT.},
keywords={},
doi={10.1109/CLEOE-EQEC.2009.5191695},
ISSN={},
month={June},} |
Thomas
Klein,
Wolfgang
Wieser,
Benjamin R.
Biedermann,
Christoph M.
Eigenwillig,
Gesa
Palte, and
Robert
Huber,
Raman pumped Fourier Domain Mode Locked (FDML) laser: Analysis of operation and application for optical coherence tomography (OCT), in CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference , IEEE, Mai2009. pp. 1-1.
Raman pumped Fourier Domain Mode Locked (FDML) laser: Analysis of operation and application for optical coherence tomography (OCT), in CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference , IEEE, Mai2009. pp. 1-1.
| DOI: | 10.1109/CLEOE-EQEC.2009.5194704 |
| Bibtex: | @INPROCEEDINGS{5194704,
author={Klein, Thomas and Wieser, Wolfgang and Biedermann, Benjamin R. and Eigenwillig, Christoph M. and Palte, Gesa and Huber, Robert},
booktitle={CLEO/Europe - EQEC 2009 - European Conference on Lasers and Electro-Optics and the European Quantum Electronics Conference},
title={Raman pumped Fourier Domain Mode Locked (FDML) laser: Analysis of operation and application for optical coherence tomography (OCT)},
year={2009},
volume={},
number={},
pages={1-1},
abstract={limitations of the sweep repetition rate of rapidly wavelength swept laser sources. Such sources can be applied for optical coherence tomography (OCT) using frequency domain detection. This technique is called swept source OCT (ss-OCT) or optical frequency domain imaging (OFDI). FDML lasers usually consist of a semiconductor optical amplifier (SOA) as laser gain medium, an output coupler, a periodically driven optical band-pass filter (FFP-TF) and an optical delay line, so that their total length is typically several kilometres.},
keywords={},
doi={10.1109/CLEOE-EQEC.2009.5194704},
ISSN={},
month={June},} |

