2021

Nicolas Detrez, Katharina Rewerts, Moritz Matthiae, Steffen Buschschlüter, Matteo M. Bonsanto, Dirk Theisen-Kunde, and Ralf Brinkmann,
Flow Controlled Air Puff Generator Towards In Situ Brain Tumor Detection Based on MHz Optical Coherence Elastography, in ECBO , Optical Society of America, Dez.2021. pp. EW4A.10.
Weblink: https://opg.optica.org/abstract.cfm?uri=ECBO-2021-EW4A.10
Bibtex: BibTeX
@inproceedings{Detrez:21,
author = {N. Detrez, K. Rewerts, M. Matthiae, S. Buschschlueter, M.M. Bonsanto, D. Theisen-Kunde and R. Brinkmann},
journal = {European Conferences on Biomedical Optics 2021 (ECBO)},
keywords = {AG-Huber_OCT},
pages = {EW4A.10},
publisher = {Optical Society of America},
title = {Flow Controlled Air Puff Generator Towards In Situ Brain Tumor Detection Based on MHz Optical Coherence Elastography},
year = {2021},
url = {https://doi.org/10.1117/12.2615022},
abstract = {A precision air puff excitation system for MHz Optical Coherence Elastography in neurosurgery was developed. It enables non-contact soft-tissue excitation down to {\textmu}N, with direct, noncontact force determination via gas flow measurement.},
}
Felix Hilge, Michael Evers, Malte Casper, Joshua Zev Glahn, Weeranut Phothong M.D., Garuna Kositratna M.D., Hinnerk Schulz-Hildebrandt, Gereon Hüttmann, and Dieter Manstein M.D.,
Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography, in Photonics in Dermatology and Plastic Surgery 2021 , Bernard Choi and Haishan Zeng, Eds. SPIE, 2021.
DOI:10.1117/12.2577822
Datei: 12.2577822
Bibtex: BibTeX
@inproceedings{10.1117/12.2577822,

title = {Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography},

author = {Felix Hilge and Michael Evers and Malte Casper and Joshua Zev Glahn and Weeranut Phothong M.D. and Garuna Kositratna M.D. and Hinnerk Schulz-Hildebrandt and Gereon H\"{u}ttmann and Dieter Manstein M.D.},

editor = {Bernard Choi and Haishan Zeng},

url = {https://doi.org/10.1117/12.2577822},

doi = {10.1117/12.2577822},

year  = {2021},

date = {2021-01-01},

booktitle = {Photonics in Dermatology and Plastic Surgery 2021},

volume = {11618},

publisher = {SPIE},

organization = {International Society for Optics and Photonics},

keywords = {},

pubstate = {published},

tppubtype = {inproceedings}

}
Mario Mordmüller, Viktoria Kleymann, Manuel A. Schaller, Mitsuru Wilson, Karl Worthmann, Matthias A. Müller, and Ralf Brinkmann,
Towards Model-based Control Techniques for Retinal Laser Treatment Using Only One Laser, in ECBO , 2021.
Datei: 12.2615851
Bibtex: BibTeX
@inproceedings{Mordmüller2021,
   author = {Mordmüller, M;Kleymann, V;Schaller, M;Wilson, M;Wothmann, K;Müller, M A and Brinkman, R},
   title = { Towards Model-based Control Techniques for Retinal Laser
Treatment Using Only One Laser},
   booktitle = {ECBO},
url = {https://doi.org/10.1117/12.2615851},
year = {2021},
   type = {Conference Proceedings}
}
Madita Göb, Sazgar Burhan, Wolfgang Draxinger, Jan Philip Kolb, and Robert Huber,
Towards densely sampled ultra-large area multi-MHz-OCT for in vivo skin measurements beyond 1 cm2/sec, in European Conferences on Biomedical Optics 2021 (ECBO) , Optical Society of America, Dez.2021. pp. EW3C.4.
DOI:10.1117/12.2616054
Weblink: https://zenodo.org/records/19854282
Bibtex: BibTeX
@inproceedings{Gob:21,
author = {Madita G\"{o}b and Sazgar Burhan and Wolfgang Draxinger and Jan Philip Kolb and Robert Huber},
booktitle = {European Conferences on Biomedical Optics 2021 (ECBO)},
journal = {European Conferences on Biomedical Optics 2021 (ECBO)},
keywords = {AG-Huber_OCT;Fourier domain mode locking; Image processing; Image quality; Optical coherence tomography; Temporal resolution; Three dimensional imaging},
pages = {EW3C.4},
publisher = {Optical Society of America},
title = {Towards densely sampled ultra-large area multi-MHz-OCT for in vivo skin measurements beyond 1 cm$^2$/sec},
year = {2021},
url = {http://www.osapublishing.org/abstract.cfm?URI=ECBO-2021-EW3C.4},
abstract = {We demonstrate a 3.3 MHz A-scan rate OCT for rapid scanning of large areas of human skin. The mosaicking performance and different OCT imaging modalities including intervolume speckle contrast are evaluated.},
}
A S Krumm,
Fiber-based Fluorescence and Reflection Measurements during Laser Lithotripsy, in ECBO , 2021.
DOI:https://doi.org/10.1117/12.2614447
Bibtex: BibTeX
@inproceedings{Krumm-2021,
   author = {Krumm, L S;Lange, B;Ozimek, T;Wießmeyer, J R;Kramer, M W;Merseburger, A S and Brinkman, R},
   title = {Fiber-based Fluorescence and Reflection Measurements during Laser Lithotripsy},
Year = {2021},
   booktitle = {ECBO},
DOI = {https://doi.org/10.1117/12.2614447},
   type = {Conference Proceedings}
}
Clara Pfäffle, Hendrik Spahr, Katharina Gercke, Sazan Burhan, David Melenberg, Yoko Miura, Gereon Hüttmann, and Dierck Hillmann,
Phase-sensitive measurements of depth dependent signal transduction in the inner plexiform layer, in SPIE BIOS , SPIE, Aug.2021.
DOI:10.1117/12.2577605
Bibtex: BibTeX
@inproceedings{RN5321,
   author = {Pfäffle, C;Spahr, H;Gercke, K;Burhan, S;Melenberg, D;Miura, Y;Hüttmann, G and Hillmann, D},
   title = {Phase-sensitive measurements of depth dependent signal transduction in the inner plexiform layer},
   booktitle = {SPIE BiOS},
   publisher = {SPIE},
   volume = {11623},
   url = {https://doi.org/10.1117/12.2577605},
   type = {Conference Proceedings}
}
Christin Grill, Simon Lotz, Torben Blömker, Mark Schmidt, Wolfgang Draxinger, Jan Philip Kolb, Christian Jirauschek, and Robert Huber,
Superposition of two independent FDML lasers, in 2021 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC) , Jun.2021. pp. 1-1.
DOI:10.1109/CLEO/Europe-EQEC52157.2021.9542126
Bibtex: BibTeX
@INPROCEEDINGS{9542126,
  author={Grill, Christin and Lotz, Simon and Blömker, Torben and Schmidt, Mark and Draxinger, Wolfgang and Kolb, Jan Philip and Jirauschek, Christian and Huber, Robert},
  booktitle={2021 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC)}, 
  title={Superposition of two independent FDML lasers}, 
  year={2021},
  volume={},
  number={},
  pages={1-1},
  abstract={Fourier domain mode locking (FDML) is a laser operating regime, which was developed in 2005 [1] . The output of this laser is a train of optical wavelength sweeps, equivalent to extremely chirped pulses with an optical bandwidth of up to 25 THz and frequency tuning rates of >10 19 Hz/s. This laser type was developed for optical coherence tomography [2] , but found recently more and more applications like LiDAR [3] , Raman microscopy [4] or two-photon microscopy [5] . The laser’s coherence properties are relevant for a better understanding of the FDML laser itself and its applications. Because of the wide sweep range and high tuning rate, the laser linewidth cannot be measured with an RF spectrometer. Superposition with a narrowband continuous wave laser only yields phase information for small fractions of the sweep [6] . However, beat signal measurements between two independent FDML lasers with equal sweep range and direction can give information about the complete sweep.},
  keywords={},
  doi={10.1109/CLEO/Europe-EQEC52157.2021.9542126},
  ISSN={},
  month={June}
}
Aaron Doug Deen,
Spectroscopic analysis through thermoelastic optical coherence microscopy, in European Conferences on Biomedical Optics , SPIE, 2021.
Datei: 12.2616068
Bibtex: BibTeX
@inproceedings{Deen2021,
   author = {Doug Deen, A;Pfeiffer, T;van Beusekom, H;Essers, J;van der Steen, A F.;Huber, Rt;van Soest, G and Wang, T},
   title = {Spectroscopic analysis through thermoelastic optical coherence microscopy},
   booktitle = {European Conferences on Biomedical Optics},
   publisher = {SPIE},
year = {2021},
   volume = {11924},
   url = {https://doi.org/10.1117/12.2616068},
   type = {Conference Proceedings}
}
Michel Wunderlich, Peter Koch, Helge Sudkamp, Michael Münst, Malte Endt, Moritz Moltmann, and Gereon Hüttmann,
Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms, in Ophthalmic Technologies XXXI , Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker, Eds. SPIE, 2021. pp. 116231Q.
DOI:10.1117/12.2583030
Datei: 12.2583030
Bibtex: BibTeX
@inproceedings{10.1117/12.2583030,
author = {Michel Wunderlich and Peter Koch and Helge Sudkamp and Michael M{\"u}nst and Malte vom Endt and Moritz Moltmann and Gereon H{\"u}ttmann},
title = {{Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms}},
volume = {11623},
booktitle = {Ophthalmic Technologies XXXI},
editor = {Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {116231Q},
keywords = {Retinal motion tracking in Off-Axis Full-Field OCT by local analy, Michel Wunderlich, Medizinsches Laserzentrum Lübeck, motion tracking, eye tracking, off-axis full-field time-domain OCT, OCT, retina},
year = {2021},
doi = {10.1117/12.2583030},
URL = {https://doi.org/10.1117/12.2583030}
}
H. S. Seifert,
Single pulse optoacoustic temperature measurement, in ECBO , 2021.
DOI:10.1117/12.2615897
Bibtex: BibTeX
@inproceedings{Seifert2021,
   author = {Seifert, E;Abbas, H. S. and Brinkman, R},
   title = {Single pulse optoacoustic temperature measurement},
   booktitle = {ECBO},
DOI = {10.1117/12.2615897},
year = {2021},
   type = {Conference Proceedings}
}

2020

Antonio López-Marín, Geert Springeling, Robert Beurskens, Heleen van Beusekom, Antonius F. W. van der Steen, Arjun D. Koch, Brett E. Bouma, and Tianshi Wang,
Shadow-free motorized capsule enables accurate beam positioning and sectorized OCT imaging of the esophagus, in Endoscopic Microscopy XV , International Society for Optics and Photonics, 2020. pp. 112140O.
Datei: 12.2545689
Bibtex: BibTeX
@inproceedings{Lopez2020,
   author = {López-Marín, Antonio;Springeling, Geert;Beurskens, Robert;Van Beusekom, Heleen;van der Steen, Antonius;Koch, Arjun D;Bouma, Brett E;Huber, Robert A;Van Soest, Gijs and Wang, Tianshi},
   title = {Shadow-free motorized capsule enables accurate beam positioning and sectorized OCT imaging of the esophagus},
   booktitle = {Endoscopic Microscopy XV},
   publisher = {International Society for Optics and Photonics},
   volume = {11214},
   pages = {112140O},
url = { https://doi.org/10.1117/12.2545689},
   type = {Conference Proceedings}
}
Christin Grill, Simon Lotz, Torben Blömker, Dominic Kastner, Tom Pfeiffer, Mark Schmidt, Wolfgang Draxinger, Christian Jirauschek, and Robert Huber,
Beating of two FDML lasers in real time, in Fiber Lasers XVII: Technology and Systems , Liang Dong, Eds. SPIE, Feb.2020. pp. 132 -- 138.
DOI:10.1117/12.2545794
Bibtex: BibTeX
@inproceedings{Grill2020,
author = {C. {Grill}, S. {Lotz}, T. {Blömker}, D. {Kastner}, T. {Pfeiffer}, S. {Karpf}, M. {Schmidt}, W. {Draxinger}, C. 
 {Jirauschek} and R. {Huber}},
title = {{Beating of two FDML lasers in real time}},
volume = {11260},
booktitle = {Fiber Lasers XVII: Technology and Systems},
editor = {Liang Dong},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {132 -- 138},
keywords = {AG-Huber_FDML, FDML laser, fiber lasers, beat signal, OCT, Optical Coherence Tomography, Fourier domain mode locking},
year = {2020},
doi = {10.1117/12.2545794},

}
Mark Schmidt, Christin Grill, Robert Huber, and Christian Jirauschek,
Coherence of Fourier Domain Mode-Locked (FDML) Lasers in the Ultra-Stable Regime, in 2020 International Conference Laser Optics (ICLO) , Nov.2020. pp. 1-1.
DOI:10.1109/ICLO48556.2020.9285488
Bibtex: BibTeX
@INPROCEEDINGS{Schmidt2020ICLO,
  author={M. {Schmidt}, C. {Grill}, R. {Huber} and C. {Jirauschek}},
  booktitle={2020 International Conference Laser Optics (ICLO)}, 
  title={Coherence of Fourier Domain Mode-Locked (FDML) Lasers in the Ultra-Stable Regime}, 
  year={2020},
keywords={AG-Huber_FDML},
  volume={},
  number={},
  pages={1-1},
  doi={10.1109/ICLO48556.2020.9285488},
}
Matthias Strauch, Jan Philip Kolb, Daniel Weng, Melanie Wacker, Wolfgang Draxinger, Nadine Merg, Jennifer Hundt, Sebastian Karpf, and Robert Huber,
Two-photon microscopy for sectioning-free virtual H&E imaging, in 104. Jahrestagung der Deutschen Gesellschaft fuer Pathologie , Jun.2020.
Weblink: https://www.pathologie-dgp.de/media/Dgp/user_upload/Verhandlungsband_2020_final__kompr._.pdf
Bibtex: BibTeX
@InProceedings{Strauch2020,
  author    = {M. Strauch, J.P. Kolb, D. Weng, M. Wacker, W. Draxinger, N. Merg, J. Hundt, S. Karpf and R. Huber},
  booktitle = {104. Jahrestagung der Deutschen Gesellschaft fuer Pathologie},
  title     = {Two-photon microscopy for sectioning-free virtual {H&E} imaging},
URL = {https://www.pathologie-dgp.de/media/Dgp/user_upload/Verhandlungsband_2020_final__kompr._.pdf},
  year      = {2020},
  keywords  = {AG-Huber_NL},
}
G Deen,
Thermo-elastic optical coherence microscopy, in Proc.SPIE , International Society for Optics and Photonics, 2020. pp. 112520H.
DOI:10.1117/12.2550998
Datei: 12.2550998
Bibtex: BibTeX
@inproceedings{Deen2020,
   author = {Deen, A D;Pfeiffer, T;H, van Beusekom.;Essers, J;Huber, R;van der Steen, A.F.W.;van Soest, G and Wang, T},
   title = {Thermo-elastic optical coherence microscopy},
   booktitle = {Proc.SPIE},
   volume = {11252},
abstarct = {The absorption of laser pulses by tissue leads not only to the generation of acoustic waves, but also to nanometer
to sub-micrometer scale displacement. After the initial expansion, a quasi-steady state is achieved in a few
microseconds. Previously we introduced the concept of thermo-elastic optical coherence tomography (TE-OCT)
to \visualise" the rapid thermo-elastic expansion by measuring the Doppler phase shift rather than \listening"
to the acoustic wave as in photoacoustic imaging. In this study, we built a microscopic setup for high-speed
3D TE-OCT imaging, by means of thermo-elastic optical coherence microscopy (TE-OCM). The repetition rate
of pulsed laser was set to 100 Hz and the line rate of the OCT system is 1.5 MHz. The OCT beam and the
laser pulse were focused upon the same location on the sample FWHM spot sizes of 300 m for the pulsed laser
and 40 m FWHM for the OCT beam. For each laser pulse, an M-mode OCT image consisting of 90 A-lines
was acquired. The Doppler phase shift was extracted by comparing the phase signal before and after the pulse
arrival. Within 6 minutes, a 3D TE-OCM image (10 x 10 x 4 mm3) can be acquired and processed. Imaging
experiments were carried out in swine meat using 1210 nm excitation wavelength to highlight lipid in tissue.
The results show that no signicant displacement was detected in swine muscle while strong displacement was
observed in lipid, owing to the optical absorption features. Furthermore, fatty tissue is easily identied in the
3D TE-OCM image while the conventional OCT images provides the structural information.},

   pages = {112520H},
   DOI = {10.1117/12.2550998},
   url = {https://doi.org/10.1117/12.2550998},
   type = {Conference Proceedings}
}
Tianshi Wang, Aaron Doug Deen, Heleen van Beusekom, and Antonius F. W. van der Steen,
Thermo-elastic optical coherence microscopy, in Advanced Chemical Microscopy for Life Science and Translational Medicine , International Society for Optics and Photonics, 2020. pp. 112520H.
DOI:https://doi.org/10.1117/12.2550998
Datei: 12.2550998.short
Bibtex: BibTeX
@inproceedings{Deen2020,
   author = {Deen, Aaron Doug;Pfeiffer, Tom;Van Beusekom, Heleen;Essers, Jeroen;Huber, Robert;van der Steen, Antonius FW;Van Soest, Gijs and Wang, Tianshi},
   title = {Thermo-elastic optical coherence microscopy},
   booktitle = {Advanced Chemical Microscopy for Life Science and Translational Medicine},
   publisher = {International Society for Optics and Photonics},
url = { https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11252/112520H/Thermo-elastic-optical-coherence-microscopy/10.1117/12.2550998.short}
   volume = {11252},
   pages = {112520H},
   type = {Conference Proceedings}
}
B L Ibey, and N. Linz,
Optical Interactions with Tissue and Cells XXXI, in Proc. of SPIE Vol , 2020. pp. 1123801-1.
DOI:10.1117/12.2569811
ISBN:ISBN: 9781510632394
Bibtex: BibTeX
@inproceedings{Linz2020,
   author = {Ibey, B L and Linz, N},
   title = {Optical Interactions with Tissue and Cells XXXI},
   booktitle = {Proc. of SPIE Vol},
   volume = {11238},
   pages = {1123801-1},
year = {2020},
   ISBN = {ISBN: 9781510632394},
   DOI = {10.1117/12.2569811},
   type = {Conference Proceedings}
}
Paul Strenge, Birgit Lange, Christin Grill, Wolfgang Draxinger, Matteo M. Bonsanto, Christian Hagel, Robert Huber, and Ralf Brinkmann,
Segmented OCT data set for depth resolved brain tumor detection validated by histological analysis, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV , SPIE, Feb.2020. pp. 82 -- 89.
DOI:10.1117/12.2545659
Bibtex: BibTeX
@inproceedings{Strenge2020,
author = {P. Strenge and B. Lange and C. Grill and W. Draxinger and M. M. Bonsanto and C. Hagel and R. Huber and R. Brinkmann},
title = {{Segmented OCT data set for depth resolved brain tumor detection validated by histological analysis}},
volume = {11228},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV},
editor = {Joseph A. Izatt and James G. Fujimoto},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82 -- 89},
keywords = {AG-Huber_OCT, Optical coherence tomography, OCT, FDML Laser, MHz-OCT, brain tumor, brain imaging, neurosurgery},
year = {2020},

URL = {  https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11228/112282O/Segmented-OCT-data-set-for-depth-resolved-brain-tumor-detection/10.1117/12.2545659.short}
}
Matthias Strauch, Jan Philip Kolb, Nadine Merg, Jennifer Hundt, Sebastian Karpf, and Robert Huber,
Evaluation of two-photon fluorescence microscopy for sectioning-free H&E imaging of different tissues, in 32nd Congress of the ESP and XXXIII International Congress of the IAP , 2020.
DOI:10.1007/s00428-020-02938-x
Bibtex: BibTeX
@InProceedings{Strauch2020a,
  author    = {M. Strauch, J.P. Kolb, N. Merg, J. Hundt, S. Karpf and R. Huber},
  booktitle = {32nd Congress of the ESP and XXXIII International Congress of the IAP},
  title     = {Evaluation of two-photon fluorescence microscopy for sectioning-free {H&E} imaging of different tissues},
  year      = {2020},
  keywords  = {AG-Huber_NL},
}

2019

E Bliedtner,
Dosimetry for microsecond selective laser trabeculoplasty, in Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX , 2019.
DOI:10.1117/12.2526987
Bibtex: BibTeX
@inproceedings{Bliedtner2019,
   author = {Bliedtner,K; Seifert, E and Brinkmann,R},
   title = {Dosimetry for microsecond selective laser trabeculoplasty},
   volume = {11079},
   DOI = {10.1117/12.2526987},
   year = {2019},
keywords = {Ophthalmology, ophthalmic optics and devices, selective laser trabeculoplasty, micro bubble detection},
booktitle =    {Proc. SPIE 11079, Medical Laser Applications
and Laser-Tissue Interactions IX},
   type = {Conference proceedings}
}
Dominic Kastner, Torben Blömker, Tom Pfeiffer, Christin Grill, Mark Schmidt, Christian Jirauschek, and Robert Huber,
Measurement of Inter-Sweep Phase Stability of an FDML Laser with a 10 kHz Tunable Ring Laser, in 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference , Optical Society of America, 2019. pp. 1-1.
DOI:10.1109/CLEOE-EQEC.2019.8872860
Bibtex: BibTeX
@inproceedings{Kastner:19,
author = {Kastner, D; Bl\"{o}mker, T; Pfeiffer, T; Grill, C; Schmidt, M; Jirauschek, C and Huber, R},
booktitle = {2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference},
journal = {2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference},
keywords = {Fourier domain mode locking; Image quality; Optical coherence tomography; Phase noise; Ring lasers; Tunable lasers},
pages = {cj_7_5},
publisher = {Optical Society of America},
title = {Measurement of Inter-Sweep Phase Stability of an FDML Laser with a 10 kHz Tunable Ring Laser},
year = {2019},
keywords = {AG-Huber_FDML, AG-Huber_OCT},
doi = { 10.1109/CLEOE-EQEC.2019.8872860},
abstract = {Fourier Domain Mode Locking (FDML) lasers are light sources that generate a sequence of narrowband optical frequency sweeps at the fundamental or harmonic of the cavity repetition rate \[1\]. This frequency swept output can also be considered as a sequence of strongly chirped, long pulses. FDML lasers are mainly used in swept source optical coherence tomography (SS-OCT), a medical imaging technique. The coherence length of the source, i.e. the intra-sweep phase stability of an FDML sweep, is decisive for the image quality and performance of OCT imaging \[2\].},
}
Rainer Haak, Martin Ahrens, Hartmut Schneider, Michaela Strumpski, Claudia Rueger, Matthias Haefer, Dirk Theisen-Kunde, and Hinnerk Schulz-Hildebrandt,
Handheld OCT probe for intraoral diagnosis on teeth, in Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II , 2019. pp. 1--4.
DOI:10.1117/12.2527185
ISBN:9781510628397
Datei: 12.2527185.full
Bibtex: BibTeX
@inproceedings{Haak2019,
author = {Haak, Rainer and Ahrens, Martin and Schneider, Hartmut and Strumpski, Michaela and Rueger, Claudia and Haefer, Matthias and H{\"{u}}ttmann, Gereon and Theisen-Kunde, Dirk and Schulz-Hildebrandt, Hinnerk},
booktitle = {Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II},
doi = {10.1117/12.2527185},
isbn = {9781510628397},
number = {110730W},
pages = {1--4},
title = {{Handheld OCT probe for intraoral diagnosis on teeth}},
keywords = {OCT,Endoskope},
year = {2019},
}
Matthias Strauch, Jan Philip Kolb, Daniel Weng, Melanie Wacker, Wolfgang Draxinger, Sebastian Karpf, and Robert Huber,
Sectioning-Free Virtual H&E Imaging of Tissue Samples with Two-Photon Microscopy, in 31st Congress of the ESP , 2019.
DOI:10.1007/s00428-019-02631-8
Bibtex: BibTeX
@InProceedings{Strauch2019,
  author    = {Strauch, Matthias and Kolb, Jan Philip and Weng, Daniel and Wacker, Melanie and Draxinger, Wolfgang and Karpf, Sebastian and Huber, Robert},
  booktitle = {31st Congress of the ESP},
  title     = {Sectioning-Free Virtual H&E Imaging of Tissue Samples with Two-Photon Microscopy},
  year      = {2019},
  keywords  = {AG-Huber_NL},
}
Julian Klee, Jan Philip Kolb, Christin Grill, Wolfgang Draxinger, Tom Pfeiffer, and Robert Huber,
Zero roll-off retinal MHz-OCT using an FDML-laser, in Optical Coherence Imaging Techniques and Imaging in Scattering Media III , SPIE, Jul.2019. pp. 110780S.
DOI:10.1117/12.2527034
Weblink: https://zenodo.org/records/19854145
Datei: 12.2527034.short
Bibtex: BibTeX
@inproceedings{10.1117/12.2527034,
author = {Julian Klee and Jan Philip Kolb and Christin Grill and Wolfgang Draxinger and Tom Pfeiffer and Robert Huber},
title = {{Zero roll-off retinal MHz-OCT using an FDML-laser}},
volume = {11078},
booktitle = {Optical Coherence Imaging Techniques and Imaging in Scattering Media III},
editor = {Maciej Wojtkowski and Stephen A. Boppart and Wang-Yuhl Oh},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {110780S},
abstract = {Optical coherence tomography (OCT) applications like ultra-widefield and full eye-length imaging are of high interest for various diagnostic purposes. In swept-source OCT these techniques require a swept light source, which is coherent over the whole imaging depth. We present a zero roll-off 1060 nm Fourier Domain Mode Locked-Laser (FDML-Laser) for retinal OCT imaging at 1.7 MHz A-scan rate and first long-range imaging results with it. Several steps such as improved dispersion compensation and frequency regulation were performed and will be discussed. Besides virtually no loss in OCT signal over the maximum depth range of 4.6 mm and very good dynamic range was observed. Roll-off measurements show no decrease of the point-spread function (PSF), while maintaining a high dynamic range.},
keywords = {optical coherence tomography, OCT, tunable laser, Fourier Domain Mode Locking, FDML, MHz OCT},
year = {2019},
doi = {10.1117/12.2527034},
URL = {https://doi.org/10.1117/12.2527034}
}
Jan Philip Kolb, Daniel Weng, Hubertus Hakert, Matthias Eibl, Wolfgang Draxinger, Tobias Meyer-Zedler, Thomas Gottschall, Ralf Brinkmann, Reginald Birngruber, Jürgen Popp, Jens Limpert, Sebastian Karpf, and Robert Huber,
Virtual HE histology by fiber-based picosecond two-photon microscopy, in Multiphoton Microscopy in the Biomedical Sciences XIX , Ammasi Periasamy; Peter T. C. So; Karsten König, Eds. International Society for Optics and Photonics, Feb.2019. pp. 108822F.
DOI:10.1117/12.2507866
Bibtex: BibTeX
@inproceedings{10.1117/12.2507866,
author = {Jan Philip Kolb and Daniel Weng and Hubertus Hakert and Matthias Eibl and Wolfgang Draxinger and Tobias Meyer and Thomas Gottschall and Ralf  Brinkmann and Reginald Birngruber and J{\"u}rgen Popp and Jens Limpert and Sebastian Nino Karpf and Robert Huber},
title = {{Virtual HE histology by fiber-based picosecond two-photon microscopy}},
volume = {10882},
booktitle = {Multiphoton Microscopy in the Biomedical Sciences XIX},
editor = {Ammasi Periasamy and Peter T. C. So and Karsten K{\"o}nig},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {108822F},
abstract = {Two-Photon Microscopy (TPM) can provide three-dimensional morphological and functional contrast in vivo. Through proper staining, TPM can be utilized to create virtual, HE equivalent images and thus can improve throughput in histology-based applications. We previously reported on a new light source for TPM that employs a compact and robust fiber-amplified, directly modulated laser. This laser is pulse-to-pulse wavelength switchable between 1064 nm, 1122 nm, and 1186 nm with an adjustable pulse duration from 50ps to 5ns and arbitrary repetition rates up to 1MHz at kW-peak powers. Despite the longer pulse duration, it can achieve similar average signal levels compared to fs-setups by lowering the repetition rate to achieve similar cw and peak power levels. The longer pulses lead to a larger number of photons per pulse, which yields single shot fluorescence lifetime measurements (FLIM) by applying a fast 4 GSamples/s digitizer. In the previous setup, the wavelengths were limited to 1064 nm and longer. Here, we use four wave mixing in a non-linear photonic crystal fiber to expand the wavelength range down to 940 nm. This wavelength is highly suitable for imaging green fluorescent proteins in neurosciences and stains such as acridine orange (AO), eosin yellow (EY) and sulforhodamine 101 (SR101) used for histology applications. In a more compact setup, we also show virtual HE histological imaging using a direct 1030 nm fiber MOPA.},
keywords = {Multiphoton Microscopy, Four Wave Mixing, FWM, Histology, Laser, Non Linear Microscopy, Two Photon Microscopy, JenLab Young Investigator Award},
year = {2019},
doi = {10.1117/12.2507866},
URL = {https://doi.org/10.1117/12.2507866}
}