Publikationen
2023
N.
Heldt,
C.
Holzhausen,
M.
Ahrens,
M.
Pieper,
P.
König, and
G.
Hüttmann,
Improved image quality in dynamic OCT imaging of airway and lung tissue by reduced imaging time and machine learning based data evaluation, in Abstract Book 11th DZL Annual Meeting , 11th DZL Annual Meeting, Fürstenfeldbruck, 14–16 June 2023, Deutsches Zentrum für Lungenforschung e. V Geschäftsstelle Aulweg 130 35392 Gießen: DZL, 072023. pp. 357.
Improved image quality in dynamic OCT imaging of airway and lung tissue by reduced imaging time and machine learning based data evaluation, in Abstract Book 11th DZL Annual Meeting , 11th DZL Annual Meeting, Fürstenfeldbruck, 14–16 June 2023, Deutsches Zentrum für Lungenforschung e. V Geschäftsstelle Aulweg 130 35392 Gießen: DZL, 072023. pp. 357.
Weblink: | https://dzl.de/wp-content/uploads/2023/06/Abstract-Book_2023-2.pdf |
Datei: | Dateilink |
A.
Leichtle,
Z.
Penxova,
T.
Kempin,
D.
Leffers,
M.
Ahrens,
P.
König,
R.
Brinkmann,
G.
Hüttmann,
K.
Bruchhage, and
H.
Schulz-Hildebrandt,
Dynamic Microscopic Optical Coherence Tomography as a New Diagnostic Tool for Otitis Media, Photonics , vol. 10, no. 6, 06 2023.
Dynamic Microscopic Optical Coherence Tomography as a New Diagnostic Tool for Otitis Media, Photonics , vol. 10, no. 6, 06 2023.
DOI: | 10.3390/photonics10060685 |
Datei: | 685 |
Bibtex: | ![]() @Article{photonics10060685, AUTHOR = {Leichtle, Anke and Penxova, Zuzana and Kempin, Thorge and Leffers, David and Ahrens, Martin and König, Peter and Brinkmann, Ralf and Hüttmann, Gereon and Bruchhage, Karl-Ludwig and Schulz-Hildebrandt, Hinnerk}, TITLE = {Dynamic Microscopic Optical Coherence Tomography as a New Diagnostic Tool for Otitis Media}, JOURNAL = {Photonics}, VOLUME = {10}, YEAR = {2023}, NUMBER = {6}, ARTICLE-NUMBER = {685}, URL = {https://www.mdpi.com/2304-6732/10/6/685}, ISSN = {2304-6732}, ABSTRACT = {Hypothesis: Otitis media (OM) can be successfully visualized and diagnosed by dynamic microscopic optical coherence tomography (dmOCT). Background: OM is one of the most common infectious diseases and, according to the WHO, one of the leading health problems with high mortality in developing countries. Despite intensive research, the only definitive treatment of therapy-refractory OM for decades has been the surgical removal of inflamed tissue. Thereby, the intra-operative diagnosis is limited to the surgeon’s visual impression. Supportive imaging modalities have been little explored and have not found their way into clinical application. Finding imaging techniques capable of identifying inflamed tissue intraoperatively, therefore, is of significant clinical relevance. Methods: This work investigated a modified version of optical coherence tomography with a microscopic resolution (mOCT) regarding its ability to differentiate between healthy and inflamed tissue. Despite its high resolution, the differentiation of single cells with mOCT is often impossible. A new form of mOCT termed dynamic mOCT (dmOCT) achieves cellular contrast using micro-movements within cells based on their metabolism. It was used in this study to establish correlative measurements with histology. Results: Using dmOCT, images with microscopic resolution were acquired on ex vivo tissue samples of chronic otitis media and cholesteatoma. Imaging with dmOCT allowed the visualization of specific and characteristic cellular and subcellular structures in the cross-sectional images, which can be identified only to a limited extent in native mOCT. Conclusion: We demonstrated for the first time a new marker-free visualization in otitis media based on intracellular motion using dmOCT.}, DOI = {10.3390/photonics10060685} } |
A.
Altmann,
M.
Eden,
G.
Hüttmann,
C.
Schell, and
R.
Rahmanzadeh,
Porphyrin-based sensor films for monitoring food spoilage, Food Packaging and Shelf Life , vol. 38, pp. 101105, 06 2023.
Porphyrin-based sensor films for monitoring food spoilage, Food Packaging and Shelf Life , vol. 38, pp. 101105, 06 2023.
DOI: | https://doi.org/10.1016/j.fpsl.2023.101105 |
Datei: | S2214289423000820 |
Bibtex: | ![]() @article{ALTMANN2023101105, title = {Porphyrin-based sensor films for monitoring food spoilage}, journal = {Food Packaging and Shelf Life}, volume = {38}, pages = {101105}, year = {2023}, issn = {2214-2894}, doi = {https://doi.org/10.1016/j.fpsl.2023.101105}, url = {https://www.sciencedirect.com/science/article/pii/S2214289423000820}, author = {Alexander Altmann and Michel Eden and Gereon Hüttmann and Christian Schell and Ramtin Rahmanzadeh}, keywords = {Biogenic amines, Sensors, Fish freshness, Food safety, Porphyrin, Smart packaging}, abstract = {To increase food safety and to minimize food waste, it is interesting for the food industry and consumers to be able to determine food spoilage continuously and non-destructively. When food of animal origin is degraded, amines are released as protein breakdown products, which could be used to monitor the freshness of meat and fish. In this work, we introduce a porphyrin-based sensor foil aimed at the detection of biogenic amines. The sensor-porphyrin is formulated on mesoporous silica. Reactivity towards moderate humidity was eliminated by dispersion of the functionalized silica in polyethylene (PE), followed by thermal extrusion resulting in PE foils. After exposure to amines, the sensor foil changes its color irreversibly from green to red. The color change is accompanied by a pronounced shift of the fluorescence spectrum, which was used as a sensitive method to detect the degradation of fish products in model experiments. Titanium dioxide particles in the foil increased the detected fluorescence emission. Experiments with fish filets showed the applicability of the sensor foils in a real-life application by indicating the degree of spoilage after several days, while the microbial growth was depicted by total viable count. We anticipate that our sensor can be an integral part of smart food packages, helping to track the freshness of food during transport or storage.} } |
S.
Latus,
S.
Grube,
T.
Eixmann,
M.
Neidhardt,
S.
Gerlach,
R.
Mieling,
G.
Hüttmann,
M.
Lutz, and
A.
Schlaefer,
A Miniature Dual-Fiber Probe for Quantitative Optical Coherence Elastography, IEEE Transactions on Biomedical Engineering , pp. 1-9, 05 2023.
A Miniature Dual-Fiber Probe for Quantitative Optical Coherence Elastography, IEEE Transactions on Biomedical Engineering , pp. 1-9, 05 2023.
DOI: | 10.1109/TBME.2023.3275539 |
Bibtex: | ![]() @ARTICLE{10122996, author={Latus, Sarah and Grube, Sarah and Eixmann, Tim and Neidhardt, Maximilian and Gerlach, Stefan and Mieling, Robin and Hüttmann, Gereon and Lutz, Matthias and Schlaefer, Alexander}, journal={IEEE Transactions on Biomedical Engineering}, title={A Miniature Dual-Fiber Probe for Quantitative Optical Coherence Elastography}, year={2023}, volume={}, number={}, pages={1-9}, doi={10.1109/TBME.2023.3275539}} |
A.
Singh,
M.
Göb,
M.
Ahrens,
T.
Eixmann,
H.
Schulz-Hildebrandt,
G.
Hüttmann,
R.
Huber, and
M.
Rahlves,
Synchronous high-speed OCT imaging with sensor less brushless DC motor and FDML laser in a phase-locked loop, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII , Joseph A. Izatt and James G. Fujimoto, Eds. SPIE, 032023. pp. 1236703.
Synchronous high-speed OCT imaging with sensor less brushless DC motor and FDML laser in a phase-locked loop, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII , Joseph A. Izatt and James G. Fujimoto, Eds. SPIE, 032023. pp. 1236703.
DOI: | 10.1117/12.2652955 |
Bibtex: | ![]() @inproceedings{10.1117/12.2652955, author = {Awanish Pratap Singh and Madita G{\"o}b and Martin Ahrens and Tim Eixmann and Hinnerk Schulz-Hildebrandt and Gereon H{\"u}ttmann and Robert Huber and Maik Rahlves}, title = {{Synchronous high-speed OCT imaging with sensor less brushless DC motor and FDML laser in a phase-locked loop}}, volume = {12367}, booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII}, editor = {Joseph A. Izatt and James G. Fujimoto}, organization = {International Society for Optics and Photonics}, publisher = {SPIE}, pages = {1236703}, abstract = {High-speed endoscopic optical coherence tomography (OCT) imaging in the MHz range has shown great potential in various medical applications ranging from cancer screening to vascular disease monitoring. High-speed imaging always suffers from non-uniform rotational distortion (NURD) due to asynchronous motor rotation with the OCT system. Several research groups have previously attempted to solve this problem, using either an expensive motor with a sensor or numerical correction after data acquisition. However, both techniques pose challenges for practical use. Therefore, in this study, we use an inexpensive sensorless brushless DC motor with a Fourier domain mode-locked (FDML) laser-based MHz OCT system and try to resolve the problem of synchronization using three different modalities, (i) Slave-mode: The FDML frequency serves as a master frequency for the motor, which is phase-locked to the FDML frequency, (ii) Master-mode: The revolution trigger obtained from the motor’s back electromotive force (BEMF) signal serves as a trigger signal for the OCT imaging system, (iii) Both: Fully synchronized setup, where the motor rotation is synchronized with the laser and the imaging system is synchronized with the motor to achieve phase-stable OCT imaging. The first case slightly fluctuates in live preview and imaging due to the absence of a revolution trigger, while the second has varying motor speeds. Therefore, we use the third case to phase-lock the motor with FDML and get a distortion-free live preview and image acquisition. Finally, we demonstrate high-speed SS-OCT structural imaging (at 3.3 MHz A-scan rates) of a finger with a 16 mm diameter probe (at 40,000 rpm).}, keywords = {Optical Coherence Tomography, Endoscopy, FDML , Closed Loop Motor Control, NURD compensation, Brushless DC Motor, Back Electromotive Force}, year = {2023}, doi = {10.1117/12.2652955}, URL = {https://doi.org/10.1117/12.2652955} } |
2022
C.
Pfäffle,
H.
Spahr,
K.
Gercke,
L.
Puyo,
S.
Höhl,
D.
Melenberg,
Y.
Miura,
G.
Hüttmann, and
D.
Hillmann,
Phase-Sensitive Measurements of Depth-Dependent Signal Transduction in the Inner Plexiform Layer, Frontiers in Medicine , vol. 9, 06 2022.
Phase-Sensitive Measurements of Depth-Dependent Signal Transduction in the Inner Plexiform Layer, Frontiers in Medicine , vol. 9, 06 2022.
DOI: | 10.3389/fmed.2022.885187 |
Datei: | fmed.2022.885187 |
Bibtex: | ![]() @article{RN5328, author = {Pfäffle, C;Spahr, H;Gercke, K;Puyo, L;Höhl, S;Melenberg, D;Miura, Y;Hüttmann, G and Hillmann, D}, title = {Phase-Sensitive Measurements of Depth-Dependent Signal Transduction in the Inner Plexiform Layer}, journal = {Frontiers in Medicine}, volume = {9}, ISSN = {2296-858X}, DOI = {10.3389/fmed.2022.885187}, keywords = {optoretinography, optical coherence tomography, phase-sensitive OCT, functional imaging, inner plexiform layer, retina}, url = {https://www.frontiersin.org/articles/10.3389/fmed.2022.885187}, year = {2022}, type = {Journal Article} } |
P
Musial,
T.
Kohlfaerber,
M.
Ahrens,
H.
Schulz-Hildebrandt,
P.
Steven, and
G.
Hüttmann,
Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride, Translational Vision Science & Technology , vol. 11(5), pp. 28-28, 2022.
Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride, Translational Vision Science & Technology , vol. 11(5), pp. 28-28, 2022.
DOI: | 10.1167/tvst.11.5.28 |
Datei: | tvst.11.5.28 |
Bibtex: | ![]() @article{Musial-2022, author = {Musial, G;Kohlfaerber, T;Ahrens, M;Schulz-Hildebrandt, H;Steven, P and Hüttmann, G}, title = {Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride}, journal = {Translational Vision Science & Technology}, keywords = {toxicity; optical coherence tomography; benzalkonium chloride}, volume = {11(5)}, pages = {28-28}, ISSN = {2164-2591}, DOI = {10.1167/tvst.11.5.28}, url = {https://doi.org/10.1167/tvst.11.5.28}, year = {2022}, type = {Journal Article} } |
T.
Kohlfaerber,
M.
Pieper,
M.
Münter,
C.
Holzhausen,
M.
Ahrens,
C.
Idel,
L.
Bruchhage,
A.
Leichtle,
P.
König,
G.
Hüttmann, and
H.
Schulz-Hildebrandt,
Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways, Biomedical Optics Express , vol. 13 (6), pp. 3211-3223, 2022.
Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways, Biomedical Optics Express , vol. 13 (6), pp. 3211-3223, 2022.
DOI: | 10.1364/BOE.456104 |
Bibtex: | ![]() @article{Kohlfarber2022, author = {Kohlfaerber, T;Pieper, M;Münter, M;Holzhausen, C;Ahrens, M;Idel, C;Bruchhage, K-L;Leichtle, A;König, P;Hüttmann, G and Schulz-Hildebrandt, H}, title = {Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways}, journal = {Biomedical Optics Express}, volume = {13 (6)}, pages = {3211-3223}, DOI = {10.1364/BOE.456104}, year = {2022}, type = {Journal Article} } |
C.
von der Burchard,
H.
Sudkamp,
J.
Tode,
C.
Ehlken,
K.
Purtskhvanidze,
M.
Moltmann,
B.
Heimes,
P.
Koch,
M.
Münst,
M.
vom Endt,
T.
Kepp,
D.
Theisen-Kunde,
I.
König,
G.
Hüttmann, and
J.
Roider,
Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study, BMJ Open , vol. 12, no. 6, pp. e055082, 2022.
Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study, BMJ Open , vol. 12, no. 6, pp. e055082, 2022.
DOI: | 10.1136/bmjopen-2021-055082 |
Datei: | e055082.abstract |
Bibtex: | ![]() @article{von-der-Burchardt2022, author = {von der Burchard, C;Sudkamp, H;Tode, J;Ehlken, C;Purtskhvanidze, K;Moltmann, M;Heimes, B;Koch, P;Münst, M;vom Endt, M;Kepp, T;Theisen-Kunde, D;König, I;Hüttmann, G and Roider, J}, title = {Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study}, journal = {BMJ Open}, volume = {12}, number = {6}, pages = {e055082}, DOI = {10.1136/bmjopen-2021-055082}, url = {http://bmjopen.bmj.com/content/12/6/e055082.abstract}, year = {2022}, type = {Journal Article} } |
2021
C.
Pfäffle,
H.
Spahr,
K.
Gercke,
S.
Burhan,
D.
Melenberg,
Y.
Miura,
G.
Hüttmann, and
D.
Hillmann,
Phase-sensitive measurements of depth dependent signal transduction in the inner plexiform layer, in SPIE BIOS , SPIE, 082021.
Phase-sensitive measurements of depth dependent signal transduction in the inner plexiform layer, in SPIE BIOS , SPIE, 082021.
DOI: | 10.1117/12.2577605 |
Bibtex: | ![]() @inproceedings{RN5321, author = {Pfäffle, C;Spahr, H;Gercke, K;Burhan, S;Melenberg, D;Miura, Y;Hüttmann, G and Hillmann, D}, title = {Phase-sensitive measurements of depth dependent signal transduction in the inner plexiform layer}, booktitle = {SPIE BiOS}, publisher = {SPIE}, volume = {11623}, url = {https://doi.org/10.1117/12.2577605}, type = {Conference Proceedings} } |
H.
Hakert,
M.
Eibl,
M.
Tillich,
R.
Pries,
G.
Hüttmann,
R.
Brinkmann,
B.
Wollenberg,
L.
Bruchhage,
S.
Karpf, and
R.
Huber,
Time-encoded stimulated Raman scattering microscopy of tumorous human pharynx tissue in the fingerprint region from 1500–1800 cm-1, Optics Letters , vol. 46(14), no. 14, pp. 3456-3459, 07 2021.
Time-encoded stimulated Raman scattering microscopy of tumorous human pharynx tissue in the fingerprint region from 1500–1800 cm-1, Optics Letters , vol. 46(14), no. 14, pp. 3456-3459, 07 2021.
DOI: | 10.1364/OL.424726 |
Bibtex: | ![]() @article{Hakert2021, author = {H. Hakert, M. Eibl, M. Tillich, R.Pries, G. Hüttmann, R. Brinkmann, B. Wollenberg, K-L. Bruchhage, S. Karpf and R. Huber}, title = {Time-encoded stimulated Raman scattering microscopy of tumorous human pharynx tissue in the fingerprint region from 1500–1800 cm-1}, journal = {Optics Letters}, volume = {46(14)}, number = {14}, pages = {3456-3459}, keywords = {AG-Huber_NL, Clinical applications, Master oscillator power amplifiers, Optical coherence tomography, Raman scattering, Stimulated Raman scattering, Stimulated scattering}, DOI = {https://doi.org/10.1364/OL.424726}, year = {2021}, type = {Journal Article} } |
T.
Peñate Medina,
J.
Kolb,
G.
Hüttmann,
R.
Huber,
O.
Peñate Medina,
N.
Larsen,
A.
Ferrari,
M.
Rafecas,
M.
Ellrichmann,
M.
Pravdivtseva,
M.
Anikeeva,
J.
Humbert,
M.
Both,
J.
Hundt, and
J.
Hövener,
Imaging Inflammation - From Whole Body Imaging to Cellular Resolution, Frontiers in immunology , vol. 12, pp. 692222-692222, 06 2021.
Imaging Inflammation - From Whole Body Imaging to Cellular Resolution, Frontiers in immunology , vol. 12, pp. 692222-692222, 06 2021.
DOI: | 10.3389/fimmu.2021.692222 |
Bibtex: | ![]() @article{PenateMedina2021, author = {Peñate Medina, T;Kolb, J P;Hüttmann, G;Huber, R;Peñate Medina, O;Ha, L;Ulloa, P;Larsen, N;Ferrari, A;Rafecas, M;Ellrichmann, M;Pravdivtseva, M S.;Anikeeva, M;Humbert, J;Both, M;Hundt, J E. and Hövener, J-B}, title = {Imaging Inflammation - From Whole Body Imaging to Cellular Resolution}, journal = {Frontiers in immunology}, keywords = {AG-Huber, MRI, PET, SPECT, optical imaging, Optical coherence tomography (OCT), precision medicine, Two-Photon microscopy (TPM), hyperpolarization}, volume = {12}, pages = {692222-692222}, ISSN = {1664-3224}, DOI = {10.3389/fimmu.2021.692222}, url = {https://pubmed.ncbi.nlm.nih.gov/34248987 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264453/}, year = {2021}, type = {Journal Article} } |
M.
Münter,
M.
Pieper,
T.
Kohlfaerber,
E.
Bodenstorfer,
M.
Ahrens,
C.
Winter,
R.
Huber,
P.
König,
G.
Hüttmann, and
H.
Schulz-Hildebrandt,
Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast, Biomed. Opt. Express , vol. 12, pp. 6024-6039, 2021.
Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast, Biomed. Opt. Express , vol. 12, pp. 6024-6039, 2021.
DOI: | 10.1364/BOE.425001 |
Bibtex: | ![]() @article{Münter2021, author = {M. Münter, M. Pieper, T. Kohlfaerber, E. Bodenstorfer, M. Ahrens, C. Winter, R. Huber, P. König, G. Hüttmann and H. Schulz-Hildebrandt}, title = {Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast}, journal = {BiomedOptE}, volume = {12(10)}, Keywords = {CMOS cameras,Full field optical coherence tomography,High numerical aperture optics, Image processing,In vivo imaging,Medical imaging,Ag-Huber}, pages = {6024-6039}, DOI = {10.1364/BOE.425001}, year = {2021}, type = {Journal Article} } |
M.
Ahrens,
C.
Idel,
P.
König,
G.
Hüttmann, and
H.
Schulz-Hildebrandt,
Voice coil based endomicroscopic optical coherence tomography probe for in vivo mucosa examination, in Endoscopic Microscopy XVI , Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter, Eds. SPIE, 2021.
Voice coil based endomicroscopic optical coherence tomography probe for in vivo mucosa examination, in Endoscopic Microscopy XVI , Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter, Eds. SPIE, 2021.
DOI: | 10.1117/12.2578787 |
Datei: | 12.2578787 |
Bibtex: | ![]() @inproceedings{10.1117/12.2578787, title = {Voice coil based endomicroscopic optical coherence tomography probe for in vivo mucosa examination}, author = {Martin Ahrens and Christian Idel and Peter K\"{o}nig and Gereon H\"{u}ttmann and Hinnerk Schulz-Hildebrandt}, editor = {Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter}, url = {https://doi.org/10.1117/12.2578787}, doi = {10.1117/12.2578787}, year = {2021}, date = {2021-01-01}, booktitle = {Endoscopic Microscopy XVI}, volume = {11620}, publisher = {SPIE}, organization = {International Society for Optics and Photonics}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } |
F.
Hilge,
M.
Evers,
M.
Casper,
J.
Glahn,
W.
M.D.,
G.
M.D.,
H.
Schulz-Hildebrandt,
G.
Hüttmann, and
D.
M.D.,
Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography, in Photonics in Dermatology and Plastic Surgery 2021 , Bernard Choi and Haishan Zeng, Eds. SPIE, 2021.
Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography, in Photonics in Dermatology and Plastic Surgery 2021 , Bernard Choi and Haishan Zeng, Eds. SPIE, 2021.
DOI: | 10.1117/12.2577822 |
Datei: | 12.2577822 |
Bibtex: | ![]() @inproceedings{10.1117/12.2577822, title = {Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography}, author = {Felix Hilge and Michael Evers and Malte Casper and Joshua Zev Glahn and Weeranut Phothong M.D. and Garuna Kositratna M.D. and Hinnerk Schulz-Hildebrandt and Gereon H\"{u}ttmann and Dieter Manstein M.D.}, editor = {Bernard Choi and Haishan Zeng}, url = {https://doi.org/10.1117/12.2577822}, doi = {10.1117/12.2577822}, year = {2021}, date = {2021-01-01}, booktitle = {Photonics in Dermatology and Plastic Surgery 2021}, volume = {11618}, publisher = {SPIE}, organization = {International Society for Optics and Photonics}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } |
H.
Schulz-Hildebrandt,
M.
Ahrens,
E.
Wilken,
C.
Holzhausen,
P.
König, and
G.
Hüttmann,
Endo-microscopic optical coherence tomography (emOCT) with dynamic contrast, in Endoscopic Microscopy XVI , Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter, Eds. SPIE, 2021.
Endo-microscopic optical coherence tomography (emOCT) with dynamic contrast, in Endoscopic Microscopy XVI , Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter, Eds. SPIE, 2021.
DOI: | 10.1117/12.2575733 |
Datei: | 12.2575733 |
Bibtex: | ![]() @inproceedings{10.1117/12.2575733, title = {Endo-microscopic optical coherence tomography (emOCT) with dynamic contrast}, author = {Hinnerk Schulz-Hildebrandt and Martin Ahrens and Michael M\"{u}nter and Elisa Wilken and Tabea Kohlf\"{a}rber and Cornelia Holzhausen and Peter K\"{o}nig and Gereon H\"{u}ttmann}, editor = {Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter}, url = {https://doi.org/10.1117/12.2575733}, doi = {10.1117/12.2575733}, year = {2021}, date = {2021-01-01}, booktitle = {Endoscopic Microscopy XVI}, volume = {11620}, publisher = {SPIE}, organization = {International Society for Optics and Photonics}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } |
S.
Jäckle,
A.
Lange,
V.
Garcia-Vazquez,
T.
Eixmann,
F.
Matysiak,
M.
Sieren,
M.
Horn,
G.
Hüttmann,
H.
Schulz-Hildebrandt,
F.
Ernst,
S.
Heldmann,
T.
Pätz, and
T.
Preusser,
Instrument localisation for endovascular aneurysm repair: Comparison of two methods based on tracking systems or using imaging, International Journal of Medical Robotics and Computer Assisted Surgery , vol. 17(6), no. 6, pp. e2327, 2021.
Instrument localisation for endovascular aneurysm repair: Comparison of two methods based on tracking systems or using imaging, International Journal of Medical Robotics and Computer Assisted Surgery , vol. 17(6), no. 6, pp. e2327, 2021.
DOI: | 10.1002/rcs.2327 |
Bibtex: | ![]() @article{Jackle2021, abstract = {Background: In endovascular aneuysm repair (EVAR) procedures, medical instruments are currently navigated with a two-dimensional imaging based guidance requiring X-rays and contrast agent. Methods: Novel approaches for obtaining the three-dimensional instrument positions are introduced. Firstly, a method based on fibre optical shape sensing, one electromagnetic sensor and a preoperative computed tomography (CT) scan is described. Secondly, an approach based on image processing using one 2D fluoroscopic image and a preoperative CT scan is introduced. Results: For the tracking based method, average errors from 1.81 to 3.13 mm and maximum errors from 3.21 to 5.46 mm were measured. For the image-based approach, average errors from 3.07 to 6.02 mm and maximum errors from 8.05 to 15.75 mm were measured. Conclusion: The tracking based method is promising for usage in EVAR procedures. For the image-based approach are applications in smaller vessels more suitable, since its errors increase with the vessel diameter.}, author = {J{\"{a}}ckle, Sonja and Lange, Annkristin and Garcia-Vazquez, Veronica and Eixmann, Tim and Matysiak, Florian and Sieren, Malte Maria and Horn, Marco and Schulz-Hildebrandt, Hinnerk and H{\"{u}}ttmann, Gereon and Ernst, Floris and Heldmann, Stefan and P{\"{a}}tz, Torben and Preusser, Tobias}, doi = {10.1002/rcs.2327}, file = {:Users/schulz-hildebrandt/Documents/Mendeley Desktop/J{\"{a}}ckle et al/International Journal of Medical Robotics and Computer Assisted Surgery/J{\"{a}}ckle et al. - 2021 - Instrument localisation for endovascular aneurysm repair Comparison of two methods based on tracking systems or.pdf:pdf}, issn = {1478596X}, journal = {International Journal of Medical Robotics and Computer Assisted Surgery}, keywords = {2D/3D registration,3D localisation,computer-assisted surgery,electromagnetic tracking system,endovascular procedures,fibre optical shape sensing}, number = {6}, pages = {e2327}, year = {2021}, title = {{Instrument localisation for endovascular aneurysm repair: Comparison of two methods based on tracking systems or using imaging}}, volume = {17} } |
M.
Wunderlich,
P.
Koch,
H.
Sudkamp,
M.
Münst,
M.
Endt,
M.
Moltmann, and
G.
Hüttmann,
Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms, in Ophthalmic Technologies XXXI , Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker, Eds. SPIE, 2021. pp. 116231Q.
Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms, in Ophthalmic Technologies XXXI , Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker, Eds. SPIE, 2021. pp. 116231Q.
DOI: | 10.1117/12.2583030 |
Datei: | 12.2583030 |
Bibtex: | ![]() @inproceedings{10.1117/12.2583030, author = {Michel Wunderlich and Peter Koch and Helge Sudkamp and Michael M{\"u}nst and Malte vom Endt and Moritz Moltmann and Gereon H{\"u}ttmann}, title = {{Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms}}, volume = {11623}, booktitle = {Ophthalmic Technologies XXXI}, editor = {Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker}, organization = {International Society for Optics and Photonics}, publisher = {SPIE}, pages = {116231Q}, keywords = {Retinal motion tracking in Off-Axis Full-Field OCT by local analy, Michel Wunderlich, Medizinsches Laserzentrum Lübeck, motion tracking, eye tracking, off-axis full-field time-domain OCT, OCT, retina}, year = {2021}, doi = {10.1117/12.2583030}, URL = {https://doi.org/10.1117/12.2583030} } |
T.
Kohlfaerber,
M.
Pieper,
P.
König,
R.
Rahmanzadeh,
G.
Hüttmann, and
H.
Schulz-Hildebrandt,
Comparison between dynamic microscopic OCT and autofluorescence multiphoton microscopy for label-free analysis of murine trachea, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV , Joseph A Izatt and James G Fujimoto, Eds. SPIE, 2021.
Comparison between dynamic microscopic OCT and autofluorescence multiphoton microscopy for label-free analysis of murine trachea, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV , Joseph A Izatt and James G Fujimoto, Eds. SPIE, 2021.
DOI: | 10.1117/12.2583811 |
Datei: | 12.2583811 |
Bibtex: | ![]() @inproceedings{10.1117/12.2583811, title = {Comparison between dynamic microscopic OCT and autofluorescence multiphoton microscopy for label-free analysis of murine trachea}, author = {Tabea Kohlfaerber and Michael M\"{u}nter and Mario Pieper and Peter K\"{o}nig and Ramtin Rahmanzadeh and Gereon H\"{u}ttmann and Hinnerk Schulz-Hildebrandt}, editor = {Joseph A Izatt and James G Fujimoto}, url = {https://doi.org/10.1117/12.2583811}, doi = {10.1117/12.2583811}, year = {2021}, date = {2021-01-01}, booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV}, volume = {11630}, publisher = {SPIE}, organization = {International Society for Optics and Photonics}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } |
M.
Cereda,
Y.
Douven,
K.
Faridpooya,
G.
Hüttmann,
T.
Eixmann,
H.
Schulz-Hildebrandt,
G.
Kronreif,
S.
van Romunde,
M.
Beelen, and
M.
de Smet,
Clinical Evaluation of an Instrument-Integrated OCT-Based Distance Sensor for Robotic Vitreoretinal Surgery, Ophthalmology Science , vol. 1(4), pp. 100085, 2021.
Clinical Evaluation of an Instrument-Integrated OCT-Based Distance Sensor for Robotic Vitreoretinal Surgery, Ophthalmology Science , vol. 1(4), pp. 100085, 2021.
DOI: | https://doi.org/10.1016/j.xops.2021.100085 |
Bibtex: | ![]() @article{Cereda-2021, author = {Cereda, M G;Parrulli, S;Douven, Y. G. M.;Faridpooya, K;van Romunde, S;Hüttmann, G;Eixmann, T;Schulz-Hildebrandt, H;Kronreif, G;Beelen, M and de Smet, M D.}, title = {Clinical Evaluation of an Instrument-Integrated OCT-Based Distance Sensor for Robotic Vitreoretinal Surgery}, journal = {Ophthalmology Science}, volume = {1(4)}, pages = {100085}, ISSN = {2666-9145}, DOI = {https://doi.org/10.1016/j.xops.2021.100085}, year = {2021}, type = {Journal Article} } |
S.
Jäckle,
T.
Eixmann,
F.
Matysiak,
M.
Sieren,
M.
Horn,
H.
Schulz-Hildebrandt,
G.
Hüttmann, and
T.
Pätz,
3D Stent Graft Guidance based on Tracking Systems for Endovascular Aneurysm Repair, Current Directions in Biomedical Engineering , vol. 7(1), no. 1, pp. 17--20, 2021.
3D Stent Graft Guidance based on Tracking Systems for Endovascular Aneurysm Repair, Current Directions in Biomedical Engineering , vol. 7(1), no. 1, pp. 17--20, 2021.
DOI: | doi:10.1515/cdbme-2021-1004 |
Datei: | cdbme-2021-1004 |
Bibtex: | ![]() @article{Jaeckle2021c, author = {J{\"{a}}ckle, Sonja and Eixmann, Tim and Matysiak, Florian and Sieren, Malte Maria and Horn, Marco and Schulz-Hildebrandt, Hinnerk and H{\"{u}}ttmann, Gereon and P{\"{a}}tz, Torben}, doi = {doi:10.1515/cdbme-2021-1004}, journal = {Current Directions in Biomedical Engineering}, year = {2021}, number = {1}, pages = {17--20}, title = {{3D Stent Graft Guidance based on Tracking Systems for Endovascular Aneurysm Repair:}}, url = {https://doi.org/10.1515/cdbme-2021-1004}, volume = {7}, } |
2020
C.
von der Burchard,
M.
Moltmann,
J.
Tode,
C.
Ehlken,
H.
Sudkamp,
D.
Theisen-Kunde,
I.
König,
G.
Hüttmann, and
J.
Roider,
Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases, Graefe's Archive for Clinical and Experimental Ophthalmology , Dez. 2020.
Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases, Graefe's Archive for Clinical and Experimental Ophthalmology , Dez. 2020.
Datei: | s00417-020-05035-6 |
Bibtex: | ![]() @article{von-derBurchard2020, author = {von der Burchard, C;Moltmann, M.;Tode, J;Ehlken, C;Sudkamp, H;Theisen-Kunde, D;König, I;Hüttmann, G and Roider, J}, title = {Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases}, journal = {Graefe's Archive for Clinical and Experimental Ophthalmology}, ISSN = {1435-702X}, url = {https://doi.org/10.1007/s00417-020-05035-6}, year = {2020}, type = {Journal Article} } |
T.
Fischer,
A.
Klinger,
D.
Smolinski,
R.
Orzekowsky-Schröder,
F.
Nitzsche,
A.
Vogel,
G.
Hüttmann, and
A.
Gebert,
High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , pp. 1-8, 2020.
High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , pp. 1-8, 2020.
Datei: | s00441-020-03167-z |
Bibtex: | ![]() @article{Fischer2020, author = {Fischer, T;Klinger, A;von Smolinski, D;Orzekowsky-Schroeder, R;Nitzsche, F;Bölke, T;Vogel, A;Hüttmann, G and Gebert, A}, title = {High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures}, journal = {Cell and Tissue Research}, pages = {1-8}, ISSN = {1432-0878}, url = {https://doi.org/10.1007/s00441-020-03167-z}, year = {2020}, type = {Journal Article} } |
S.
Jäckle,
V.
Garcia-Vazquez,
T.
Eixmann,
F.
Matysiak,
F.
von Haxthausen,
M.
Sieren,
H.
Schulz-Hildebrandt,
G.
Hüttmann,
F.
Ernst,
M.
Kleemann, and
T.
Pätz,
Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair, Int J Comp Assis Radiology and Surgery , 2020.
Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair, Int J Comp Assis Radiology and Surgery , 2020.
ISBN: | 1861-6429 |
Datei: | s11548-020-02167-2 |
Bibtex: | ![]() @article{jackle2020, title = {Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair}, author = {Jäckle,S; Garcia-Vazquez,V; Eixmann, T; Matysiak, F; von Haxthausen,F; Sieren; M m; Schulz-Hildebrandt, H; H\"{u}ttmann, G; Ernst, F; Kleemann, M and P\"{a}tz, T}, url = {https://doi.org/10.1007/s11548-020-02167-2}, isbn = {1861-6429}, year = {2020}, date = {2020-04-06}, journal = {Int J Comp Assis Radiology and Surgery}, abstract = {During endovascular aneurysm repair (EVAR) procedures, medical instruments are guided with two-dimensional (2D) fluoroscopy and conventional digital subtraction angiography. However, this requires X-ray exposure and contrast agent is used, and the depth information is missing. To overcome these drawbacks, a three-dimensional (3D) guidance approach based on tracking systems is introduced and evaluated.}, keywords = {HSH}, pubstate = {published}, tppubtype = {article} } |
C.
Yao,
F.
Rudnitzki,
Y.
He,
Z.
Zhang,
G.
Hüttmann, and
R.
Rahmanzadeh,
Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods, JBio , 2020.
Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods, JBio , 2020.
DOI: | 10.1002/jbio.202000017 |
Bibtex: | ![]() @article{Rahmanzadeh-2020, author = {Yao, C;Rudnitzki, F;He, Y;Zhang, Z;Hüttmann, G and Rahmanzadeh, R}, title = {Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods}, journal = {JBio}, ISSN = {1864-063X}, DOI = {10.1002/jbio.202000017}, Year = {2020}, type = {Journal Article} } |
M.
Münter,
M.
Pieper,
M.
Casper,
M.
Ahrens,
T.
Kohlfaerber,
R.
Rahmanzadeh,
P.
König,
G.
Hüttmann, and
H.
Schulz-Hildebrandt,
Dynamic contrast in scanning microscopic OCT, Optic Letters , 2020.
Dynamic contrast in scanning microscopic OCT, Optic Letters , 2020.
Datei: | 2003.00006 |
Bibtex: | ![]() @article{Münter2020, author = {Münter, M;Endt, M v;Pieper, M;Casper, M;Ahrens, M;Kohlfaerber, T;Rahmanzadeh, R;König, P;Hüttmann, G and Schulz-Hildebrandt, H}, title = {Dynamic contrast in scanning microscopic OCT}, journal = {Optic Letters}, url = {https://arxiv.org/abs/2003.00006}, year = {2020}, type = {Journal Article} } |
A.
Rakhymzhan,
L.
Reuter,
R.
Raspe,
D.
Bremer,
J.
Heidelin,
V.
Andresen,
R.
Günther,
R.
Leben,
S.
Cheremukhin,
H.
Schulz-Hildebrandt,
M.
Bixel,
R.
Adams,
H.
Radbruch,
G.
Hüttmann,
A.
Hauser, and
R.
Niesner,
Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging, Cytometry Part A , vol. 97, no. 5, pp. 515-527, 2020.
Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging, Cytometry Part A , vol. 97, no. 5, pp. 515-527, 2020.
DOI: | 10.1002/cyto.a.24012 |
Bibtex: | ![]() @article{Schulz-Hildebrandt-2020, author = {Rakhymzhan, A;Reuter, L;Raspe, R;Bremer, D;Günther, R;Leben, R;Heidelin, J;Andresen, V;Cheremukhin, S;Schulz-Hildebrandt, H;Bixel, M G.;Adams, R H.;Radbruch, H;Hüttmann, G;Hauser, A E. and Niesner, R A.}, title = {Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging}, year = {2020}, journal = {Cytometry Part A}, volume = {97}, number = {5}, pages={515-527}, ISSN = {1552-4922}, DOI = {10.1002/cyto.a.24012}, type = {Journal Article} } |
H.
Schneider,
M.
Ahrens,
M.
Strumpski,
C.
Rüger,
M.
Häfer,
G.
Hüttmann,
D.
Theisen-Kunde,
H.
Schulz-Hildebrandt, and
R.
Haak,
An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations, J Clin Med , vol. 9(10), 2020.
An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations, J Clin Med , vol. 9(10), 2020.
DOI: | 10.3390/jcm9103257 |
Bibtex: | ![]() @article{schneider2020, author = {Schneider, H.;Ahrens, M.;Strumpski, M.;Ruger, C.;Hafer, M.;Huettmann, G.;Theisen-Kunde, D.;Schulz-Hildebrandt, H. and Haak, R.}, title = {An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations}, journal = {J Clin Med}, volume = {9(10)}, keywords = {OCT; intraoral probe; carious lesions; caries diagnosis; dental restorations}, ISSN = {2077-0383 (Print) 2077-0383 (Linking)}, DOI = {10.3390/jcm9103257}, year = {2020}, type = {Journal Article} } |
V.
Matkivsky,
A.
Moiseev,
P.
Shilyagin,
A.
Rodionov,
H.
Spahr,
C.
Pfäffle,
G.
Hüttmann,
D.
Hillmann, and
G.
Gelikonov,
Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function, Journal of Biophotonics , vol. 13(10), pp. e202000112, 2020.
Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function, Journal of Biophotonics , vol. 13(10), pp. e202000112, 2020.
DOI: | 10.1002/jbio.202000112 |
Bibtex: | ![]() @article{Matkivsky2020, author = {Matkivsky, V;Moiseev, A;Shilyagin, P;Rodionov, A;Spahr, H;Pfäffle, C;Hüttmann, G;Hillmann, D and Gelikonov, G}, title = {Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function}, journal = {Journal of Biophotonics}, volume = {13(10)}, pages = {e202000112}, ISSN = {1864-063X}, DOI = {10.1002/jbio.202000112}, year = {2020}, type = {Journal Article} } |
2019
M.
Horn,
S.
Jäckle,
F.
von Haxthausen,
T.
Eixmann,
H.
Schulz-Hildebrandt,
G.
Hüttmann,
J.
Bouchagiar,
F.
Matysiak,
M.
Kaschwich,
M.
Kleemann,
F.
Ernst,
V.
Garcia-Vazquez, and
T.
Pätz,
First Steps into Catheter Guidance Including Shape Sensing for Endovascular Aneurysm Repair Procedures, European Journal of Vascular and Endovascular Surgery , vol. 58, no. 6, pp. e610--e611, Dez. 2019. W.B. Saunders.
First Steps into Catheter Guidance Including Shape Sensing for Endovascular Aneurysm Repair Procedures, European Journal of Vascular and Endovascular Surgery , vol. 58, no. 6, pp. e610--e611, Dez. 2019. W.B. Saunders.
DOI: | 10.1016/J.EJVS.2019.09.091 |
Bibtex: | ![]() @proceedings{Horn2019b, title = {First Steps into Catheter Guidance Including Shape Sensing for Endovascular Aneurysm Repair Procedures}, author = {Marco Horn and Sonja J\"{a}ckle and Felix von Haxthausen and Tim Eixmann and Hinnerk Schulz-Hildebrandt and Gereon H\"{u}ttmann and Juljan Bouchagiar and Florian Matysiak and Mark Kaschwich and Markus Kleemann and Floris Ernst and Ver\'{o}nica Garc\'{i}a-V\'{a}zquez and Torben P\"{a}tz}, doi = {10.1016/J.EJVS.2019.09.091}, issn = {1078-5884}, year = {2019}, date = {2019-12-13}, journal = {European Journal of Vascular and Endovascular Surgery}, volume = {58}, number = {6}, pages = {e610--e611}, publisher = {W.B. Saunders}, keywords = {Sensing, Fiber}, pubstate = {published}, tppubtype = {proceedings} } |