Tjalfe Laedtke

@article{RN5536,
   author = {Burhan, Sazgar;Göb, Madita;Pieper, Mario;Laedtke, Tjalfe;Grahl, Thorge;Münter, Michael;Schulz-Hildebrandt, Hinnerk;Hüttmann, Gereon;König, Peter and Huber, Robert},
   title = {Label-free volumetric imaging of porcine kidney tissue over extended areas using dynamic MHz-OCT},
   journal = {Scientific Reports},
   volume = {15},
   number = {1},
   pages = {32426},
   ISSN = {2045-2322},
   DOI = {10.1038/s41598-025-15032-6},
   url = {https://doi.org/10.1038/s41598-025-15032-6},
   year = {2025},
   type = {Journal Article}
}

@inproceedings{10.1117/12.3046216,
author = {Sazgar Burhan and Madita G{\"o}b and Mario Pieper and Tjalfe Laedtke and Thorge Grahl and Michael M{\"u}nter and Hinnerk Schulz-Hildebrandt and Gereon H{\"u}ttmann and Peter K{\"o}nig and Robert Huber},
title = {{Large-area dynamic contrast MHz optical coherence tomography for label-free imaging of porcine tissue}},
volume = {13305},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIX},
editor = {Rainer A. Leitgeb and Yoshiaki Yasuno},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {1330502},
abstract = {We demonstrate a 3.2 MHz-OCT system for inter-volumetric dynamic optical coherence tomography of ex vivo porcine kidney tissue. Employing a home-built Fourier Domain mode locking (FDML) laser with a 1310 nm wavelength, the system achieved a lateral resolution of 3.48 μm and a frame rate of 612 Hz. A motorized XYZ positioning stage enabled the precise acquisition of multiple volumes, which were seamlessly stitched together to generate a comprehensive dataset with a total area of 2.6 × 2.6 mm<sup>2</sup>. Validations against histological sections confirmed the system’s ability to visualize cellular tissue structures.},
keywords = {Optical Coherence Tomography, Megahertz OCT, Fourier Domain Mode Locking, Dynamic OCT, Functional OCT, Three-dimensional image acquisition, Tissue Dynamics, Kidney},
year = {2025},
doi = {10.1117/12.3046216},
URL = {https://doi.org/10.1117/12.3046216}
}

@inproceedings{Laedtke:25,
author = {Tjalfe Laedtke and Sazgar Burhan and Simon Lotz and Madita G\"{o}b and Robert Huber},
booktitle = {European Conferences on Biomedical Optics 2025},
journal = {European Conferences on Biomedical Optics 2025},
keywords = {Image registration; Imaging systems; Phase shift; Spatial resolution; Speckle noise; Speckle patterns},
pages = {W1D.4},
publisher = {Optica Publishing Group},
title = {Speckle Reduction Through Angular Compounding in Robotically Assisted MHz-OCT},
year = {2025},
url = {https://opg.optica.org/abstract.cfm?URI=ECBO-2025-W1D.4},
doi = {10.1364/ECBO.2025.W1D.4},
abstract = {We demonstrate speckle reduction in robotically assisted MHz-OCT by angular compounding. The robot is used to acquire images from different angles, which, after registration, are used for efficient speckle averaging without loss of spatial resolution.},
}