Wolfgang Draxinger

@inproceedings{10.1117/12.3045055,
author = {Marie Klufts and Wolfgang Draxinger and Simon Lotz and Robert Huber},
title = {{1.7MHz, 840nm swept-source ophthalmic OCT}},
volume = {13300},
booktitle = {Ophthalmic Technologies XXXV},
editor = {Daniel X. Hammer and Derek Nankivil and Yuankai K. Tao},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {1330004},
keywords = {swept source, SS-OCT, FDML , Retinal imaging, ophthalmic imaging, OCT, 850 nm, short wavelength},
year = {2025},
doi = {10.1117/12.3045055},
URL = {https://doi.org/10.1117/12.3045055}
}

@inproceedings{10.1117/12.3046222,
author = {Sazgar Burhan and Berenice Schulte and Madita G{\"o}b and Awanish Pratap Singh and Bayan Mustafa and Simon Lotz and Wolfgang Draxinger and Philipp Lamminger and Yasmeine Saker and Tim Eixmann and Martin Ahrens and Marvin Heimke and Tillmann Heinze and Thilo Wedel and Maik Rahlves and Mark Ellrichmann and Robert Huber},
title = {{Switchable lateral resolution real-time MHz-OCT rectoscopy for enhanced colorectal disease diagnosis}},
volume = {13305},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIX},
editor = {Rainer A. Leitgeb and Yoshiaki Yasuno},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {1330512},
abstract = {Endoscopic optical coherence tomography (OCT) offers in vivo live visualization of transmural structures with histological resolution, making it a valuable tool in medical imaging. In gastroenterology, OCT endoscopy is particularly advantageous for assessing rectal wall layers, providing superior axial and lateral resolution compared to conventional rectal endoscopic ultrasound. However, the large diameter and uneven colon surface present challenges for comprehensive imaging. Extending the OCT imaging range addresses this issue by enabling a thorough examination of the entire colon, facilitating the detection of surface polyps, tumors, and their infiltration depth. Once these regions of interest are identified, high-resolution imaging becomes essential for detailed evaluation. To meet these demands, this study integrates two different imaging modes, an extended-range mode, and a high-detail mode, within a rigid rectoscope. The extended-range mode enables visualization of deeper structures, while the high-detail mode enhances image quality for precise, contact-based assessments. The system allows seamless, real-time transitions between the modes using a 3.2MHz-OCT system and a fiber‑optic MEMS switch.},
keywords = {Optical Coherence Tomography, Megahertz OCT, Fourier Domain Mode Locking, Three-dimensional image acquisition, Rectal Imaging, Long-Range Imaging, Non-Invasive Diagnostic Imaging, Tumor Assessment},
year = {2025},
doi = {10.1117/12.3046222},
URL = {https://doi.org/10.1117/12.3046222}
}

@inproceedings{Detrez:25,
author = {Nicolas Detrez and Dirk Theisen-Kunde and Wolfgang Draxinger and Thies H\"{o}rcher and Veit Danicke and Sazgar Burhan and Jessica Kren and Matteo Mario Bonsanto and Robert Huber and Ralf Brinkmann},
booktitle = {European Conferences on Biomedical Optics 2025},
journal = {European Conferences on Biomedical Optics 2025},
keywords = {Coherence and statistical optics; Elastography; Modes; Optical coherence tomography; Phase; Phase measurement},
pages = {M3A.36},
publisher = {Optica Publishing Group},
title = {Co-Robot Supported Air-Jet Based Optical Coherence Elastography Towards In-Situ Brain Tumor Tissue Delineation},
year = {2025},
url = {https://opg.optica.org/abstract.cfm?URI=ECBO-2025-M3A.36},
doi = {10.1364/ECBO.2025.M3A.36},
abstract = {Accurate tumor delineation in neurosurgery is challenging. We developed an in-situ optical coherence elastography system using air-jet excitation and phase based full-range OCT. The challenges in transitioning from ex vivo to in-situ application are presented.},
}

@inproceedings{10.1117/12.3047226,
author = {Paul Strenge and Birgit Lange and Wolfgang Draxinger and Dirk Theisen-Kunde and Sonja Spahr-Hess and Matteo M. Bonsanto and Robert Huber and Ralf Brinkmann and Heinz Handels},
title = {{Enhancing brain tumor detection using optical coherence tomography and variational autoencoders}},
volume = {13410},
booktitle = {Medical Imaging 2025: Clinical and Biomedical Imaging},
editor = {Barjor S. Gimi and Andrzej Krol},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {134101P},
abstract = {Neurosurgical intervention is critical in brain tumor treatment, with long-term survival closely linked to the extent of tumor resection. The goal is to completely remove tumor tissue while preserving healthy tissue, a challenging task due to the diffuse nature of some brain tumors, such as glioblastoma, which infiltrate healthy tissue in ways that are difficult to distinguish histologically. Current intraoperative imaging techniques, including MRI and fluorescence microscopy, are limited in reliably identifying tumor tissue. Optical coherence tomography (OCT) offers a promising alternative, providing non-invasive, high-resolution cross-sectional images. This study investigates the use of a variational autoencoder (VAE) in combination with an evidential learning framework to enhance the classification of brain tissues in OCT images. The classification approach, applied to ex vivo OCT images captured at a wavelength of 1300 nm, achieved an average precision of 0.87 and a recall of 0.88 for the discrimination of healthy and tumorous brain tissue with consideration of prediction uncertainties. This method demonstrated improved discrimination between healthy white matter and tumor-infiltrated white matter compared to previous studies.},
keywords = {brain tumor, OCT, variational autoencoders, glioblastoma, classification, medical imaging, brain, evidential learning},
year = {2025},
doi = {10.1117/12.3047226},
URL = {https://doi.org/10.1117/12.3047226}
}

@inproceedings{Draxinger:25,
author = {Wolfgang Draxinger and Simon Lotz and Allegra Behr and Madita G\"{o}b and Robert Huber},
booktitle = {European Conferences on Biomedical Optics 2025},
journal = {European Conferences on Biomedical Optics 2025},
keywords = {Absolute distance measurement; Field programmable gate arrays; Imaging systems; Light sources; Scanners; Swept sources},
pages = {W5D.5},
publisher = {Optica Publishing Group},
title = {Lifting constraints on multi-kHz raster-line scanning frequency matching in multi-MHz Swept-Source OCT imaging systems},
year = {2025},
url = {https://opg.optica.org/abstract.cfm?URI=ECBO-2025-W5D.5},
doi = {10.1364/ECBO.2025.W5D.5},
abstract = {The established synchronization scheme of SS-OCT calls for the raster-line frequency to be a remainder-less divider of the sweep frequency. Two methods are presented that increase flexibility in scanner operation.},
}

@inproceedings{Lotz:25,
author = {Simon Lotz and Wolfgang Draxinger and Anneli Dick and Robert Huber},
booktitle = {European Conferences on Biomedical Optics 2025},
journal = {European Conferences on Biomedical Optics 2025},
keywords = {Fiber Bragg gratings; Imaging techniques; Laser sources; Optical buffers; Swept sources; Three dimensional imaging},
pages = {W5D.4},
publisher = {Optica Publishing Group},
title = {Megahertz FDML laser with on-the-fly adjustable sweep rate between 835 kHz and 13.4 MHz},
year = {2025},
url = {https://opg.optica.org/abstract.cfm?URI=ECBO-2025-W5D.4},
doi = {10.1364/ECBO.2025.W5D.4},
abstract = {We present a Megahertz FDML laser which can be automatically, and on-the-fly switched to speed values between 830 kHz and 13.4 MHz using optical switches in the buffer stage.},
}

@inproceedings{Singh:25,
author = {Awanish Pratap Singh and Madita G\"{o}b and Sazgar Burhan and Nikolay Tesmer and Wolfgang Draxinger and Simon Lotz and Berenice Schulte and Mark Ellrichmann and Robert Huber and Maik Rahlves},
booktitle = {European Conferences on Biomedical Optics 2025},
journal = {European Conferences on Biomedical Optics 2025},
keywords = {Clinical applications; Endoscopic imaging; Imaging systems; Laser sources; Optical components; Three dimensional reconstruction},
pages = {M1C.1},
publisher = {Optica Publishing Group},
title = {Multi-MHz-OCT Endoscopic Imaging with an Automated Pullback Mechanism},
year = {2025},
url = {https://opg.optica.org/abstract.cfm?URI=ECBO-2025-M1C.1},
doi = {10.1364/ECBO.2025.M1C.1},
abstract = {We present an automated pullback mechanism for MHz-OCT rectoscopy to address non-uniform motion artifacts via consistent probe retraction. High-resolution images of a test sample demonstrate uniform frame spacing, reduced distortion, and improved imaging accuracy, validating its potential for in-vivo clinical applications.},
}

@article{Draxinger:24,
author = {Wolfgang Draxinger and Nicolas Detrez and Paul Strenge and Veit Danicke and Dirk Theisen-Kunde and Lion Sch\"{u}tzeck and Sonja Spahr-Hess and Patrick Kuppler and Jessica Kren and Wolfgang Wieser and Matteo Mario Bonsanto and Ralf Brinkmann and Robert Huber},
journal = {Biomed. Opt. Express},
keywords = {Brain imaging; Imaging systems; In vivo imaging; Magnetic resonance imaging; Speckle imaging; Spectral domain optical coherence tomography},
number = {10},
pages = {5960--5979},
publisher = {Optica Publishing Group},
title = {Microscope integrated MHz optical coherence tomography system for neurosurgery: development and clinical in-vivo imaging},
volume = {15},
month = {Oct},
year = {2024},
url = {https://opg.optica.org/boe/abstract.cfm?URI=boe-15-10-5960},
doi = {10.1364/BOE.530976},
abstract = {Neurosurgical interventions on the brain are impeded by the requirement to keep damages to healthy tissue at a minimum. A new contrast channel enhancing the visual separation of malign tissue should be created. A commercially available surgical microscope was modified with adaptation optics adapting the MHz speed optical coherence tomography (OCT) imaging system developed in our group. This required the design of a scanner optics and beam delivery system overcoming constraints posed by the mechanical and optical parameters of the microscope. High quality volumetric OCT C-scans with dense sample spacing can be acquired in-vivo as part of surgical procedures within seconds and are immediately available for post-processing.},
}

@Article{Schulte2024,
author={Schulte, B.; Burhan, S.; Singh, A. P.; Draxinger, W.; Lotz, S.; Heimke, M.; Heinze, T.; Wedel, T.; Rahlves, M.; Huber, R.; Ellrichmann, M.},
title={Hochaufl{\"o}sende Rektoskopie mittels dual-mode MHz optischer Koh{\"a}renztomographie -- ein Schritt zur real time 3D Endoskopie},
journal={Z Gastroenterol},
year={2024},
month={Sep},
day={26},
publisher={Georg Thieme Verlag KG},
volume={62},
number={09},
pages={KV 355},
issn={0044-2771},
doi={10.1055/s-0044-1790019},
url={http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0044-1790019},
url={https://doi.org/10.1055/s-0044-1790019},
language={DE}
}

@article{RN5474,
   author = {Schulte, Berenice;Göb, Madita;Singh, Awanish Pratap;Lotz, Simon;Draxinger, Wolfgang;Heimke, Marvin;pieper, Mario;Heinze, Tillmann;Wedel, Thilo;Rahlves, Maik;Huber, Robert and Ellrichmann, Mark},
   title = {High-resolution rectoscopy using MHz optical coherence tomography: a step towards real time 3D endoscopy},
   journal = {Scientific Reports},
   volume = {14},
   number = {1},
   pages = {4672},
   ISSN = {2045-2322},
   DOI = {10.1038/s41598-024-55338-5},
   url = {https://doi.org/10.1038/s41598-024-55338-5},
   year = {2024},
   type = {Journal Article}
}

@article { Microscopeintegratedopticalcoherencetomographyforinvivohumanbraintumordetectionwithartificialintelligence,
      author = "Patrick Kuppler and Paul Strenge and Birgit Lange and Sonja Spahr-Hess and Wolfgang Draxinger and Christian Hagel and Dirk Theisen-Kunde and Ralf Brinkmann and Robert Huber and Volker Tronnier and Matteo Mario Bonsanto",
      title = "Microscope-integrated optical coherence tomography for in vivo human brain tumor detection with artificial intelligence",
      journal = "Journal of Neurosurgery",
      year = "2024",
      publisher = "American Association of Neurological Surgeons",
      doi = "10.3171/2024.1.JNS231511",
      pages=      "1 - 9",
      url = "https://thejns.org/view/journals/j-neurosurg/aop/article-10.3171-2024.1.JNS231511/article-10.3171-2024.1.JNS231511.xml"
}

@inproceedings{10.1117/12.2670907,
author = {Paul Strenge and Birgit Lange and Wolfgang Draxinger and Christian Hagel and Christin Grill and Veit Danicke and Dirk Theisen-Kunde and Sonja Spahr-Hess and Matteo M. Bonsanto and Robert Huber and Heinz Handels and Ralf Brinkmann},
title = {{Demarcation of brain and tumor tissue with optical coherence tomography using prior neural networks}},
volume = {12632},
booktitle = {Optical Coherence Imaging Techniques and Imaging in Scattering Media V},
editor = {Benjamin J. Vakoc and Maciej Wojtkowski and Yoshiaki Yasuno},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {126321P},
keywords = {Brain Tumor, OCT, Optical Coherence Tomography, Prior Network, Glioblastoma Multiforme, Neural Network, Classification},
year = {2023},
doi = {10.1117/12.2670907},
URL = {https://doi.org/10.1117/12.2670907}
}

@inproceedings{10.1117/12.2670953,
author = {Wolfgang Draxinger and Dirk Theisen-Kunde and Lion Schuetz and Nicolas Detrez and Paul Strenge and Maximilian Rixius and Veit Danicke and Wolfgang Wieser and Jessica Kren and Patrick Kuppler and Sonja Spar-Hess and Matteo Mario Bonsanto M.D. and Ralf Brinkmann and Robert Huber},
title = {{Microscope integrated realtime high density 4D MHz-OCT in neurosurgery: a depth and tissue resolving visual contrast channel and the challenge of fused presentation}},
volume = {12627},
booktitle = {Translational Biophotonics: Diagnostics and Therapeutics III},
editor = {Zhiwei Huang and Lothar D. Lilge},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {126270W},
abstract = {Microscope integrated realtime 4D MHz-OCT operating at high scanning densities are capable of capturing additional visual contrast resolving depth and tissue. Even within a plain C-scan en-face projection structures are recognizable, that are not visible in a white light camera image. With advanced post processing methods, such as absorbtion coefficient mapping, and morphological classifiers more information is extraced. Presentation to the user in an intuitive way poses practical challenges that go beyond the implementation of a mere overlay display. We present our microscope integrated high speed 4D OCT imaging system, its clinical study use for in-vivo brain tissue imaging, and user feedback on the presentation methods we developed.},
keywords = {optical coherence tomography, neurosurgery, tissue contrast, image fusion, surgical guidance, theranostics},
year = {2023},
doi = {10.1117/12.2670953},
URL = {https://doi.org/10.1117/12.2670953}
}

@INPROCEEDINGS{10231419,
  author={Lotz, Simon and Göb, Madita and Draxinger, Wolfgang and Dick, Anneli and Huber, Robert},
  booktitle={2023 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC)}, 
  title={13.4 MHz FDML Laser for Intra-Surgical Optical Coherence Tomography}, 
  year={2023},
  volume={},
  number={},
  pages={1-1},
  doi={10.1109/CLEO/Europe-EQEC57999.2023.10231419}}

Kuppler P, Strenge P, Lange B, Spahr-Hess S, Draxinger W, Hagel C, Theisen-Kunde D, Brinkmann R, Huber R, Tronnier V and Bonsanto MM (2023) The neurosurgical benefit of contactless in vivo optical coherence tomography regarding residual tumor detection: A clinical study. Front. Oncol. 13:1151149. doi: 10.3389/fonc.2023.1151149

@inproceedings{10.1117/12.2648505,
author = {Wolfgang Draxinger and Dirk Theisen-Kunde and Lion Sch{\"u}tzeck and Nicolas Detrez and Paul Strenge and Veit Danicke and Jessica Kren and Patrick Kuppler and Sonja Spahr-Hess and Matteo Mario Bonsanto and Ralf Brinkmann and Robert Huber},
title = {{High speed 4D in-vivo OCT imaging of the human brain: creating high density datasets for machine learning toward identification of malign tissue in real time}},
volume = {12390},
booktitle = {High-Speed Biomedical Imaging and Spectroscopy VIII},
editor = {Kevin K. Tsia and Keisuke Goda},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {123900D},
abstract = {Neuro-surgery is challenged by the difficulties of determining brain tumor boundaries during excisions. Optical coherence tomography is investigated as an imaging modality for providing a viable contrast channel. Our MHz-OCT technology enables rapid volumetric imaging, suitable for surgical workflows. We present a surgical microscope integrated MHz-OCT imaging system, which is used for the collection of in-vivo images of human brains, with the purpose of being used in machine learning systems that shall be trained to identify and classify tumorous tissue.},
keywords = {optical coherence tomography, brain tumor, neurosurgery, machine learning, contrast augmentation, histology dataset, clinical study, in-vivo imaging},
year = {2023},
doi = {10.1117/12.2648505},
URL = {https://doi.org/10.1117/12.2648505}
}

@inproceedings{10.1117/12.2649963,
author = {Paul Strenge and Birgit Lange and Wolfgang Draxinger and Christian Hagel and Christin Grill and Veit Danicke and Dirk Theisen-Kunde and Sonja Spahr-Hess and Matteo M. Bonsanto and Robert Huber and Heinz Handels and Ralf Brinkmann},
title = {{Dual wavelength analysis and classification of brain tumor tissue with optical coherence tomography}},
volume = {12368},
booktitle = {Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI},
editor = {Caroline Boudoux and James W. Tunnell},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {1236805},
abstract = {The ill-defined tumor borders of glioblastoma multiforme pose a major challenge for the surgeon during tumor resection,  since the goal of the tumor resection is the complete removal, while saving as much healthy brain tissue as possible. In  recent years, optical coherence tomography (OCT) was successfully used to classify white matter from tumor infiltrated  white matter by several research groups. Motivated by these results, a dataset was created, which consisted of sets of  corresponding ex vivo OCT images, which were acquired by two OCT-systems with different properties (e.g. wavelength  and resolution). Each image was annotated with semantic labels. The labels differentiate between white and gray matter  and three different stages of tumor infiltration. The data from both systems not only allowed a comparison of the ability of  a system to identify the different tissue types present during the tumor resection, but also enable a multimodal tissue  analysis evaluating corresponding OCT images of the two systems simultaneously. A convolutional neural network with  dirichlet prior was trained, which allowed to capture the uncertainty of a prediction. The approach increased the sensitivity  of identifying tumor infiltration from 58 % to 78 % for data with a low prediction uncertainty compared to a previous  monomodal approach. },
keywords = {optical coherence tomography, oct, brain, classification, tumor, dual wavelength, glioblastoma multiforme, tissue analysis},
year = {2023},
doi = {10.1117/12.2649963},
URL = {https://doi.org/10.1117/12.2649963}
}

@article{Strenge-2022,
   author = {Strenge, P.;Lange, B.;Grill,C.;Danicke,V.;Theisen-Kunde, D.;Hagel, C.;Spahr-Hess, S.;;Bonsanto, Matteo M.;Handels, H.; and Huber, R.;Brinkmann, R.},
   title = {Differentiation of different stages of brain tumor infiltration using optical coherence tomography: Comparison of two systems and histology},
   journal = {Frontiers in Oncology},
Keywords = {AG-Huber_FDML, AG-Huber_OCT, brain, tumor, glioblastoma multiforme, OCT, neural network, attenuation (absorption)
coefficient, optical coherence tomography},
   DOI = {https://doi.org/10.3389/fonc.2022.896060},
   url = {https://www.frontiersin.org/articles/10.3389/fonc.2022.896060/full},
   year = {2022},
   type = {Journal Article}
}

@article{Grill2022,
  doi = {10.1038/s42005-022-00960-w},
  year = {2022},
  publisher = {Springer Science and Business Media {LLC}},
  volume = {{5}},
  number = {{1}},
  author = {C. Grill, T. Bl\"{o}mker, M. Schmidt, D. Kastner, T. Pfeiffer, J.P. Kolb, W. Draxinger, S. Karpf, C. Jirauschek and R. Huber},
  title = {Towards phase-stabilized Fourier domain mode-locked frequency combs},
  journal = {{Communications Physics}},
keywords={AG-Huber_FDML, FDML, Fourier domain mode locking, phase, frequency comb, coherence, beating}
}

@article{Strenge2022,
   author = {Strenge, P;Lange, B;Grill, C;Draxinger, W;Danicke, V;Theisen-Kunde, D;Hagel, C;Spahr-Hess, S;Bonsanto, Matteo M.;Huber, R;Handels, H and Brinkmann, R},
   title = {Registration of histological brain images onto optical coherence tomography images based on shape information},
keywords = {brain, glioblastoma multiforme, shape, OCT, optical coherence tomography, AG-Huber_OCT,},
   journal = {Physics in Medicine & Biology},
   ISSN = {0031-9155},
   url = {http://iopscience.iop.org/article/10.1088/1361-6560/ac6d9d},
   year = {2022},
   type = {Journal Article}
}

@article{Gob:22,
author = {Madita G\"{o}b and Tom Pfeiffer and Wolfgang Draxinger and Simon Lotz and Jan Philip Kolb and Robert Huber},
journal = {Biomed. Opt. Express},
keywords = {High speed imaging; Image processing; Image quality; In vivo imaging; Range imaging; Vertical cavity surface emitting lasers},
number = {2},
pages = {713--727},
publisher = {Optica Publishing Group},
title = {Continuous spectral zooming for in vivo live 4D-OCT with MHz A-scan rates and long coherence},
volume = {13},
month = {Feb},
year = {2022},
url = {https://opg.optica.org/boe/abstract.cfm?URI=boe-13-2-713},
doi = {10.1364/BOE.448353},
abstract = {We present continuous three-dimensional spectral zooming in live 4D-OCT using a home-built FDML based OCT system with 3.28 MHz A-scan rate. Improved coherence characteristics of the FDML laser allow for imaging ranges up to 10 cm. For the axial spectral zoom feature, we switch between high resolution and long imaging range by adjusting the sweep range of our laser. We present a new imaging setup allowing for synchronized adjustments of the imaging range and lateral field of view during live OCT imaging. For this, a novel inline recalibration algorithm was implemented that enables numerical k-linearization of the raw OCT fringes for every frame instead of every volume. This is realized by acquiring recalibration data within the dead time of the raster scan at the turning points of the fast axis scanner. We demonstrate in vivo OCT images of fingers and hands at different resolution modes and show real three-dimensional zooming during live 4D-OCT. A three-dimensional spectral zooming feature for live 4D-OCT is expected to be a useful tool for a wide range of biomedical, scientific and research applications, especially in OCT guided surgery.},
}

@inproceedings{Strenge:21,
author = {P. Strenge, B. Lange, C. Grill, W. Draxinger, V. Danicke, D. Theisen-Kunde, H. Handels, M. M. Bonsanto, C. Hagel, R. Huber and R. Brinkmann},
journal = {European Conferences on Biomedical Optics 2021 (ECBO)},
keywords = {AG-Huber_OCT; Absorption coefficient; Attenuation coefficient; Fourier domain mode locking; Multiple scattering; Optical coherence tomography; Spectral domain optical coherence tomography},
pages = {EW1C.7},
publisher = {Optical Society of America},
title = {Comparison of two optical coherence tomography systems to identify human brain tumor},
year = {2021},
url = {https://doi.org/10.1117/12.2616044},
abstract = {The identification of ex vivo brain tumor tissue was investigated with two different optical coherence tomography systems exploiting two optical parameters. The optical parameters were calculated from semantically labelled OCT B-scans.},
}

@inproceedings{Gob:21,
author = {Madita G\"{o}b and Sazgar Burhan and Wolfgang Draxinger and Jan Philip Kolb and Robert Huber},
booktitle = {European Conferences on Biomedical Optics 2021 (ECBO)},
journal = {European Conferences on Biomedical Optics 2021 (ECBO)},
keywords = {AG-Huber_OCT;Fourier domain mode locking; Image processing; Image quality; Optical coherence tomography; Temporal resolution; Three dimensional imaging},
pages = {EW3C.4},
publisher = {Optical Society of America},
title = {Towards densely sampled ultra-large area multi-MHz-OCT for in vivo skin measurements beyond 1 cm$^2$/sec},
year = {2021},
url = {http://www.osapublishing.org/abstract.cfm?URI=ECBO-2021-EW3C.4},
abstract = {We demonstrate a 3.3 MHz A-scan rate OCT for rapid scanning of large areas of human skin. The mosaicking performance and different OCT imaging modalities including intervolume speckle contrast are evaluated.},
}

@INPROCEEDINGS{9542126,
  author={Grill, Christin and Lotz, Simon and Blömker, Torben and Schmidt, Mark and Draxinger, Wolfgang and Kolb, Jan Philip and Jirauschek, Christian and Huber, Robert},
  booktitle={2021 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC)}, 
  title={Superposition of two independent FDML lasers}, 
  year={2021},
  volume={},
  number={},
  pages={1-1},
  abstract={Fourier domain mode locking (FDML) is a laser operating regime, which was developed in 2005 [1] . The output of this laser is a train of optical wavelength sweeps, equivalent to extremely chirped pulses with an optical bandwidth of up to 25 THz and frequency tuning rates of >10 19 Hz/s. This laser type was developed for optical coherence tomography [2] , but found recently more and more applications like LiDAR [3] , Raman microscopy [4] or two-photon microscopy [5] . The laser’s coherence properties are relevant for a better understanding of the FDML laser itself and its applications. Because of the wide sweep range and high tuning rate, the laser linewidth cannot be measured with an RF spectrometer. Superposition with a narrowband continuous wave laser only yields phase information for small fractions of the sweep [6] . However, beat signal measurements between two independent FDML lasers with equal sweep range and direction can give information about the complete sweep.},
  keywords={},
  doi={10.1109/CLEO/Europe-EQEC52157.2021.9542126},
  ISSN={},
  month={June}
}