Cuiping Yao, Florian Rudnitzki, Yida He, Zhenxi Zhang, Gereon Hüttmann, and Ramtin Rahmanzadeh,
Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods, JBio , 2020.
DOI:10.1002/jbio.202000017
Bibtex: BibTeX
@article{Rahmanzadeh-2020,
   author = {Yao, C;Rudnitzki, F;He, Y;Zhang, Z;Hüttmann, G and Rahmanzadeh, R},
   title = {Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods},
   journal = {JBio},
   
   ISSN = {1864-063X},
   DOI = {10.1002/jbio.202000017},
  Year = {2020},
   type = {Journal Article}
}
Ramtin Rahmanzadeh, Florian Rudnitzki, and Gereon Hüttmann,
Two ways to inactivate the Ki-67 protein—Fragmentation by nanoparticles, crosslinking with fluorescent dyes, Journal of Biophotonics , pp. e201800460, 2019.
DOI:10.1002/jbio.201800460
Datei: jbio.201800460
Bibtex: BibTeX
@article{Rahmanzadeh-2019,
   author = {Rahmanzadeh, R;Rudnitzki, F and Hüttmann, G},
   title = {Two ways to inactivate the Ki-67 protein—Fragmentation by nanoparticles, crosslinking with fluorescent dyes},
   journal = {Journal of Biophotonics},
   Year = {2019},
   pages = {e201800460},
   ISSN = {1864-063X},
   DOI = {10.1002/jbio.201800460},
   url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201800460},
   type = {Journal Article}
}
Cuiping Yao, Florian Rudnitzki, Gereon Hüttmann, Zhenxi Zhang, and Ramtin Rahmanzadeh,
Important factors for cell-membrane permeabilization by gold nanoparticles activated by nanosecond-laser irradiation, International Journal of Nanomedicine , vol. 12, pp. 5659-5672, 2017.
DOI:10.2147/IJN.S140620
Bibtex: BibTeX
@article{Yao2017,
   author = {Yao, C; Rudnitzki, F; Hüttmann, G; Zhang, Zand Rahmanzadeh, R},
   title = {Important factors for cell-membrane permeabilization by gold nanoparticles activated by nanosecond-laser irradiation},
journal = {International Journal of Nanomedicine},
  
   pages = {5659-5672},
   DOI = {10.2147/IJN.S140620},
   year = {2017},
   type = {Journal Article}
}
Sijia Wang, Gereon Hüttmann, Florian Rudnitzki, Heyke Diddens-Tschoeke, Zhenxi Zhang, and Ramtin Rahmanzadeh,
Indocyanine green as effective antibody conjugate for intracellular molecular targeted photodynamic therapy, Journal of Biomedical Optics , vol. 21, no. 7, pp. 078001-078001, 2016.
DOI:10.1117/1.JBO.21.7.078001
Bibtex: BibTeX
@article{Wang2016,
   author = {Wang, Sijia and Hüttmann, Gereon and Rudnitzki, Florian and Diddens-Tschoeke, Heyke and Zhang, Zhenxi and Rahmanzadeh, Ramtin},
   title = {Indocyanine green as effective antibody conjugate for intracellular molecular targeted photodynamic therapy},
   journal = {Journal of Biomedical Optics},
   volume = {21},
   number = {7},
   pages = {078001-078001},
   note = {10.1117/1.JBO.21.7.078001},
   abstract = {Abstract.  The fluorescent dye indocyanine green (ICG) is clinically approved and has been applied for ophthalmic and intraoperative angiography, measurement of cardiac output and liver function, or as contrast agent in cancer surgery. Though ICG is known for its photochemical effects, it has played a minor role so far in photodynamic therapy or techniques for targeted protein-inactivation. Here, we investigated ICG as an antibody-conjugate for the selective inactivation of the protein Ki-67 in the nucleus of cells. Conjugates of the Ki-67 antibody TuBB-9 with different amounts of ICG were synthesized and delivered into HeLa and OVCAR-5 cells through conjugation to the nuclear localization sequence. Endosomal escape of the macromolecular antibodies into the cytoplasm was optically triggered by photochemical internalization with the photosensitizer BPD. The second light irradiation at 690 nm inactivated Ki-67 and subsequently caused cell death. Here, we show that ICG as an antibody-conjugate can be an effective photosensitizing agent. Best effects were achieved with 1.8 ICG molecules per antibody. Conjugated to antibodies, the ICG absorption peaks vary proportionally with concentration. The absorption of ICG above 650 nm within the optical window of tissue opens the possibility of selective Ki-67 inactivation deep inside of tissues.},
   ISSN = {1083-3668},
   year = {2016},
   type = {Journal Article}
}
Florian Rudnitzki, Marco Bever, Ramtin Rahmanzadeh, Katrin Brieger, Elmar Endl, and Jürgen Groll,
Bleaching of plasmon-resonance absorption of gold nanorods decreases efficiency of cell destruction, J Biomed Opt , vol. 17, no. 5, pp. 058003, 2012.
DOI:10.1117/1.JBO.17.5.058003
Bibtex: BibTeX
@Article{pmid22612150,
   Author="Rudnitzki, F.  and Bever, M.  and Rahmanzadeh, R.  and Brieger, K.  and Endl, E.  and Groll, J.  and Huttmann, G. ",
   Title="{{B}leaching of plasmon-resonance absorption of gold nanorods decreases efficiency of cell destruction}",
   Journal="J Biomed Opt",
   Year="2012",
   Volume="17",
   Number="5",
   Pages="058003",
   Month="May"
}
Ramtin Rahmanzadeh, Florian Rudnitzki, Elmar Endl, and Tayyaba Hasan,
Targeted molecular effects through laser-irradiated nanoabsorbers, in Proc. SPIE , Newsrrom, SPIE, Eds. 2011.
DOI:10.1117/2.1201102.003548
Bibtex: BibTeX
@inproceedings{Hüttmann2011,
   author = {Hüttmann, Gereon and Rahmanzadeh, Ramtin and Rudnitzki, Florian and Endl, Elmar and Hasan, Tayyaba},
   title = {Targeted molecular effects through laser-irradiated nanoabsorbers},
   editor = {Newsrrom, SPIE},
   DOI = {10.1117/2.1201102.003548},
   type = {Conference Proceedings},
   year = { 2011}
}