Publikationen

2020

S. Jäckle, V. Garcia-Vazquez, T. Eixmann, F. Matysiak, F. von Haxthausen, M. Sieren, H. Schulz-Hildebrandt, G. Hüttmann, F. Ernst, M. Kleemann, and T. Pätz,
Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair, Int J Comp Assis Radiology and Surgery , 2020.
ISBN:1861-6429
Datei: s11548-020-02167-2
Bibtex: BibTeX
@article{jackle2020,
title = {Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair},
author = {Jäckle,S; Garcia-Vazquez,V; Eixmann, T; Matysiak, F; von Haxthausen,F; Sieren; M m; Schulz-Hildebrandt, H;  H\"{u}ttmann, G; Ernst, F; Kleemann, M and P\"{a}tz, T},
url = {https://doi.org/10.1007/s11548-020-02167-2},

isbn = {1861-6429},
year = {2020},
date = {2020-04-06},
journal = {Int J  Comp Assis Radiology and Surgery},
abstract = {During endovascular aneurysm repair (EVAR) procedures, medical instruments are guided with two-dimensional (2D) fluoroscopy and conventional digital subtraction angiography. However, this requires X-ray exposure and contrast agent is used, and the depth information is missing. To overcome these drawbacks, a three-dimensional (3D) guidance approach based on tracking systems is introduced and evaluated.},
keywords = {HSH},
pubstate = {published},
tppubtype = {article}
}
T. Fischer, A. Klinger, D. Smolinski, R. Orzekowsky-Schröder, F. Nitzsche, A. Vogel, G. Hüttmann, and A. Gebert,
High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , pp. 1-8, 2020.
Datei: s00441-020-03167-z
Bibtex: BibTeX
@article{Fischer2020,
   author = {Fischer, T;Klinger, A;von Smolinski, D;Orzekowsky-Schroeder, R;Nitzsche, F;Bölke, T;Vogel, A;Hüttmann, G and Gebert, A},
   title = {High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures},
   journal = {Cell and Tissue Research},
   pages = {1-8},
   ISSN = {1432-0878},
   url = {https://doi.org/10.1007/s00441-020-03167-z},
   year = {2020},
   type = {Journal Article}
}
V. Matkivsky, A. Moiseev, P. Shilyagin, A. Rodionov, H. Spahr, C. Pfäffle, G. Hüttmann, D. Hillmann, and G. Gelikonov,
Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function, Journal of Biophotonics , vol. 13(10), pp. e202000112, 2020.
DOI:10.1002/jbio.202000112
Bibtex: BibTeX
@article{Matkivsky2020,
   author = {Matkivsky, V;Moiseev, A;Shilyagin, P;Rodionov, A;Spahr, H;Pfäffle, C;Hüttmann, G;Hillmann, D and Gelikonov, G},
   title = {Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function},
   journal = {Journal of Biophotonics},
   volume = {13(10)},
   pages = {e202000112},
   ISSN = {1864-063X},
   DOI = {10.1002/jbio.202000112},
   year = {2020},
   type = {Journal Article}
}
C. Yao, F. Rudnitzki, Y. He, Z. Zhang, G. Hüttmann, and R. Rahmanzadeh,
Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods, JBio , 2020.
DOI:10.1002/jbio.202000017
Bibtex: BibTeX
@article{Rahmanzadeh-2020,
   author = {Yao, C;Rudnitzki, F;He, Y;Zhang, Z;Hüttmann, G and Rahmanzadeh, R},
   title = {Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods},
   journal = {JBio},
   
   ISSN = {1864-063X},
   DOI = {10.1002/jbio.202000017},
  Year = {2020},
   type = {Journal Article}
}
H. Schneider, M. Ahrens, M. Strumpski, C. Rüger, M. Häfer, G. Hüttmann, D. Theisen-Kunde, H. Schulz-Hildebrandt, and R. Haak,
An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations, J Clin Med , vol. 9(10), 2020.
DOI:10.3390/jcm9103257
Bibtex: BibTeX
@article{schneider2020,
   author = {Schneider, H.;Ahrens, M.;Strumpski, M.;Ruger, C.;Hafer, M.;Huettmann, G.;Theisen-Kunde, D.;Schulz-Hildebrandt, H. and Haak, R.},
   title = {An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations},
   journal = {J Clin Med},
   volume = {9(10)},
   keywords = {OCT; intraoral probe; carious lesions; caries diagnosis; dental restorations},
   ISSN = {2077-0383 (Print)
2077-0383 (Linking)},
   DOI = {10.3390/jcm9103257},
   
   year = {2020},
   type = {Journal Article}
}
A. Rakhymzhan, L. Reuter, R. Raspe, D. Bremer, J. Heidelin, V. Andresen, R. Günther, R. Leben, S. Cheremukhin, H. Schulz-Hildebrandt, M. Bixel, R. Adams, H. Radbruch, G. Hüttmann, A. Hauser, and R. Niesner,
Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging, Cytometry Part A , vol. 97, no. 5, pp. 515-527, 2020.
DOI:10.1002/cyto.a.24012
Bibtex: BibTeX
@article{Schulz-Hildebrandt-2020,
   author = {Rakhymzhan, A;Reuter, L;Raspe, R;Bremer, D;Günther, R;Leben, R;Heidelin, J;Andresen, V;Cheremukhin, S;Schulz-Hildebrandt, H;Bixel, M G.;Adams, R H.;Radbruch, H;Hüttmann, G;Hauser, A E. and Niesner, R A.},
   title = {Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging},
  year = {2020},
   journal = {Cytometry Part A},
   volume = {97},
   number = {5},
   pages={515-527},
   ISSN = {1552-4922},
   DOI = {10.1002/cyto.a.24012},
   type = {Journal Article}
}

2019

M. Horn, S. Jäckle, F. von Haxthausen, T. Eixmann, H. Schulz-Hildebrandt, G. Hüttmann, J. Bouchagiar, F. Matysiak, M. Kaschwich, M. Kleemann, F. Ernst, V. Garcia-Vazquez, and T. Pätz,
First Steps into Catheter Guidance Including Shape Sensing for Endovascular Aneurysm Repair Procedures, European Journal of Vascular and Endovascular Surgery , vol. 58, no. 6, pp. e610--e611, Dez. 2019. W.B. Saunders.
DOI:10.1016/J.EJVS.2019.09.091
Bibtex: BibTeX
@proceedings{Horn2019b,
title = {First Steps into Catheter Guidance Including Shape Sensing for Endovascular Aneurysm Repair Procedures},
author = {Marco Horn and Sonja J\"{a}ckle and Felix von Haxthausen and Tim Eixmann and Hinnerk Schulz-Hildebrandt and Gereon H\"{u}ttmann and Juljan Bouchagiar and Florian Matysiak and Mark Kaschwich and Markus Kleemann and Floris Ernst and Ver\'{o}nica Garc\'{i}a-V\'{a}zquez and Torben P\"{a}tz},
doi = {10.1016/J.EJVS.2019.09.091},
issn = {1078-5884},
year  = {2019},
date = {2019-12-13},
journal = {European Journal of Vascular and Endovascular Surgery},
volume = {58},
number = {6},
pages = {e610--e611},
publisher = {W.B. Saunders},
keywords = {Sensing, Fiber},
pubstate = {published},
tppubtype = {proceedings}
}
H. Spahr, C. Pfäffle, S. Burhan, L. Kutzner, F. Hilge, G. Hüttmann, and D. Hillmann,
Phase-sensitive interferometry of decorrelated speckle patterns, Scientific report , vol. 9, 08 2019.
DOI:10.1038/s41598-019-47979-8
Bibtex: BibTeX
@article{RN5217,
   author = {Spahr, Hendrik;Pfäffle, Clara;Burhan, Sazan;Kutzner, Lisa;Hilge, Felix;Hüttmann, Gereon and Hillmann, Dierck},
   title = {Phase-sensitive interferometry of decorrelated speckle patterns},
   journal = {Scientific Reports},
   volume = {9},
   number = {1},
   pages = {11748},
   ISSN = {2045-2322},
   DOI = {10.1038/s41598-019-47979-8},
   url = {https://doi.org/10.1038/s41598-019-47979-8},
   year = {2019},
   type = {Journal Article}
}
H. Spahr, C. Pfäffle, G. Hüttmann, and D. Hillmann,
Artifacts in speckle tracking and multi-aperture Doppler OCT imaging of lateral motion, Opt. Lett. , vol. 44, no. 6, pp. 1315--1318, 03 2019. Optica Publishing Group.
DOI:10.1364/OL.44.001315
Datei: abstract.cfm
Bibtex: BibTeX
@article{RN5085,
   author = {Spahr, H;Pfäffle, C;Hüttmann, G and Hillmann, D},
   title = {Artifacts in speckle tracking and multi-aperture
Doppler OCT imaging of lateral motion},
   journal = {Optics letters},
   volume = {44(5)},
   pages = {1315-1318},
   DOI = {https://doi.org/10.1364/OL.44001315},
   url = {https://doi.org/10.1364/OL.44001315},
   year = {2019},
   type = {Journal Article}
}
R. Rahmanzadeh, F. Rudnitzki, and G. Hüttmann,
Two ways to inactivate the Ki-67 protein—Fragmentation by nanoparticles, crosslinking with fluorescent dyes, Journal of Biophotonics , pp. e201800460, 2019.
DOI:10.1002/jbio.201800460
Datei: jbio.201800460
Bibtex: BibTeX
@article{Rahmanzadeh-2019,
   author = {Rahmanzadeh, R;Rudnitzki, F and Hüttmann, G},
   title = {Two ways to inactivate the Ki-67 protein—Fragmentation by nanoparticles, crosslinking with fluorescent dyes},
   journal = {Journal of Biophotonics},
   Year = {2019},
   pages = {e201800460},
   ISSN = {1864-063X},
   DOI = {10.1002/jbio.201800460},
   url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201800460},
   type = {Journal Article}
}
C. Pfäffle, H. Spahr, L. Kutzner, S. Burhan, F. Hilge, Y. Miura, G. Hüttmann, and D. Hillmann,
Simultaneous functional imaging of neuronal and photoreceptor layers in living human retina, Optics Letters 44(23) , pp. 5671-5674, 2019.
DOI:10.1364/OL.44.005671
Bibtex: BibTeX
@article{Pfäffle2019,
   author = {Pfäffle, C;Spahr, H;Kutzner, L;Burhan, S;Hilge, F;Miura, Y;Hüttmann, G and Hillmann, D},
   title = {Simultaneous functional imaging of neuronal and photoreceptor layers in living human retina},
   journal = {Optics Letters 44(23)},
 
   pages = {5671-5674},
   DOI = {10.1364/OL.44.005671},
   
   year = {2019},
   type = {Journal Article}
}
T. Kepp, C. Droigk, M. Casper, M. Evers, G. Hüttmann, N. Salma, D. Manstein, M. Heinrich, and H. Handels,
Segmentation of mouse skin layers in optical coherence tomography image data using deep convolutional neural networks, Biomed Opt Expr 10(7) , pp. 3484-3496, 2019.
DOI:10.1364/BOE.10.003484
Datei: BOE.10.003484
Bibtex: BibTeX
@article{Hüttmann2019,
   author = {Kepp, T;Droigk, C;Casper, M;Evers, M;Hüttmann, G;Salma, N;Manstein, D;Heinrich, M P. and Handels, H},
   title = {Segmentation of mouse skin layers in optical coherence tomography image data using deep convolutional neural networks},
   journal = {Biomed Opt Expr 10(7)},
  
   pages = {3484-3496},
   DOI = {10.1364/BOE.10.003484},
   url = {https://doi.org/10.1364/BOE.10.003484},
   year = {2019},
   type = {Journal Article}
}
T. Kohlfaerber, D. Shujun, R. Rahmanzadeh, T. Jüngst, J. Groll, H. Schulz-Hildebrandt, and G. Hüttmann,
Investigation of cell dynamics in 3D cell spheroids and cell interaction with 3D printed scaffolds by mOCT, Transactions on Additive Manufacturing Meets Medicine 1(1) , 2019.
DOI:10.18416/AMMM.2019.1909S03P19
Bibtex: BibTeX
@article{Kohlfärber2019,
   author = {Kohlfaerber, T;Ding, S;Rahmanzadeh, R;Jüngst, T;Groll, J;Schulz-Hildebrandt, H and Hüttmann, G},
   title = {Investigation of cell dynamics in 3D cell spheroids and cell interaction with 3D printed scaffolds by mOCT},
   journal = {Transactions on Additive Manufacturing Meets Medicine 1(1)},
   
   DOI = {10.18416/AMMM.2019.1909S03P19},
   year = {2019},
   type = {Journal Article}
}
D. Hillmann, C. Pfäffle, H. Spahr, H. Sudkamp, G. Franke, and G. Hüttmann,
In Vivo FF-SS-OCT Optical Imaging of Physiological Responses to Photostimulation of Human Photoreceptor Cells, in High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics , Bille, Josef F., Eds. Cham: Springer International Publishing, 2019, pp. 181-194.
ISBN:978-3-030-16638-0
Datei: 978-3-030-16638-0_8
Bibtex: BibTeX
@inbook{Hillmann2019,
   author = {Hillmann, Dierck;Pfäffle, Clara;Spahr, Hendrik;Sudkamp, Helge;Franke, Gesa and Hüttmann, Gereon},
   title = {In Vivo FF-SS-OCT Optical Imaging of Physiological Responses to Photostimulation of Human Photoreceptor Cells},
   booktitle = {High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics},
   editor = {Bille, Josef F.},
   publisher = {Springer International Publishing},
   address = {Cham},
   pages = {181-194},
   ISBN = {978-3-030-16638-0},
   
   url = {https://doi.org/10.1007/978-3-030-16638-0_8},
   year = {2019},
   type = {Book Section}
}
T. Fischer, A. Klinger, D. Smolinski, R. Orzekowsky-Schroeder, F. Nitzsche, A. Vogel, G. Hüttmann, and A. Gebert,
High-resolution imaging of the living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , 2019.
Bibtex: BibTeX
@article{Vogel-2019-1,
   author = {Fischer, T;Klinger, A;Smolinski, D von;Orzekowsky-Schroeder, R;Nitzsche, F;Vogel, A;Hüttmann, G and Gebert, A},
   title = {High-resolution imaging of the living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures},
   journal = {Cell and Tissue Research},
   ISSN = {0302-766X (Print) 
1432-0878 (Online)},
   year = {2019},
   type = {Journal Article}
}
D. Hillmann, C. Pfäffle, H. Spahr, S. Burhan, L. Kutzner, F. Hilge, and G. Hüttmann,
Computational adaptive optics for optical coherence tomography using multiple randomized subaperture correlations, Opt Lett 44 (15) , pp. 3905-3908, 2019.
DOI:10.1364/OL.44.003905
Datei: 31368998
Bibtex: BibTeX
@article{Hillmann2019,
   author = {Hillmann, D.;Pfaffle, C.;Spahr, H.;Burhan, S.;Kutzner, L.;Hilge, F. and Hüttmann, G.},
   title = {Computational adaptive optics for optical coherence tomography using multiple randomized subaperture correlations},
   journal = {Opt Lett 44 (15)},
 
   pages = {3905-3908},
   ISSN = {1539-4794 (Electronic)
0146-9592 (Linking)},
   DOI = {10.1364/OL.44.003905},
   url = {https://www.ncbi.nlm.nih.gov/pubmed/31368998},
   year = {2019},
   type = {Journal Article}
}

2018

H. Schulz-Hildebrandt, T. Pfeiffer, T. Eixmann, S. Lohmann, M. Ahrens, J. Rehra, W. Draxinger, P. König, R. Huber, and G. Hüttmann,
High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography, Opt. Lett. , vol. 43, no. 18, pp. 4386-4389, 09 2018. Optica Publishing Group.
DOI:10.1364/OL.43.004386
Bibtex: BibTeX
@article{Schulz-Hildebrandt:18,
author = {Hinnerk Schulz-Hildebrandt and Tom Pfeiffer and Tim Eixmann and Sabrina Lohmann and Martin Ahrens and Joshua Rehra and Wolfgang Draxinger and Peter K\"{o}nig and Robert Huber and Gereon H\"{u}ttmann},
journal = {Opt. Lett.},
keywords = {Fiber optics imaging; Endoscopic imaging; Medical and biological imaging; Optical coherence tomography; Fourier domain mode locking; Image quality; Optical coherence tomography; Single mode fibers; Step index fibers; Three dimensional imaging},
number = {18},
pages = {4386--4389},
publisher = {Optica Publishing Group},
title = {High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography},
volume = {43},
month = {Sep},
year = {2018},
url = {https://opg.optica.org/ol/abstract.cfm?URI=ol-43-18-4386},
doi = {10.1364/OL.43.004386},
abstract = {We present a forward-viewing fiber scanning endoscope (FSE) for high-speed volumetric optical coherence tomography (OCT). The reduction in size of the probe was achieved by substituting the focusing optics by an all-fiber-based imaging system which consists of a combination of scanning single-mode fibers, a glass spacer, made from a step-index multi-mode fiber, and a gradient-index fiber. A lateral resolution of 11 $\mu$m was achieved at a working distance of 1.2 mm. The newly designed piezo-based FSE has an outer diameter of 1.6 mm and a rigid length of 13.5 mm. By moving the whole imaging optic in spirals for scanning the sample, the beam quality remains constant over the entire field of view with a diameter of 0.8 mm. The scanning frequency was adjusted to 1.22 kHz for use with a 3.28 MHz Fourier domain mode locked OCT system. Densely sampled volumes have been imaged at a rate of 6 volumes per second.},
}
H. Sudkamp, D. Hillmann, P. Koch, M. vom Endt, H. Spahr, M. Münst, C. Pfäffle, R. Birngruber, and G. Hüttmann,
Simple approach for aberration-corrected OCT imaging of the human retina, Opt Lett , vol. 43, no. 17, pp. 4224, 08 2018.
DOI:10.1364/ol.43.004224
Bibtex: BibTeX
@article{Sudkamp2018a,
   author = {Sudkamp, H; Hillmann, D; Koch, P;vom Endt, M; Spahr, H; Münst, M; Pfäffle, C; Birngruber, R and Hüttmann, G},
   title = {Simple approach for aberration-corrected OCT imaging of the human retina},
   journal = {Opt Lett},
   
   pages = {4224},
   ISSN = {0146-9592
1539-4794},
   DOI = {10.1364/ol.43.004224},
   year = {2018},
   type = {Journal Article},
   keyword = {Retome}
}
H. Schulz-Hildebrandt, M. Münter, M. Ahrens, H. Spahr, D. Hillmann, P. König, and G. Hüttmann,
Coherence and diffraction limited resolution in microscopic OCT by a unified approach for the correction of dispersion and aberrations, in 2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources , 2018. pp. 105910O.
DOI:10.1117/12.2303755
ISBN:9781510616745
Bibtex: BibTeX
@inproceedings{Schulz-Hildebrandt2018a,
title = {Coherence and diffraction limited resolution in microscopic OCT by a unified approach for the correction of dispersion and aberrations},
author = {Schulz-Hildebrandt,H; M\"{u}nter, M; Ahrens,M; Spahr, H; Hillmann, D; K\"{o}nig, P and  H\"{u}ttmann, G},
doi = {10.1117/12.2303755},
isbn = {9781510616745},
year = {2018},
date = {2018-03-05},
booktitle = {2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources},
volume = {10591},
pages = {105910O},
abstract = {Optical coherence tomography (OCT) images scattering tissues with 5 to 15 μm resolution. This is usually not sufficient for a distinction of cellular and subcellular structures. Increasing axial and lateral resolution and compensation of artifacts caused by dispersion and aberrations is required to achieve cellular and subcellular resolution. This includes defocus which limit the usable depth of field at high lateral resolution. OCT gives access the phase of the scattered light and hence correction of dispersion and aberrations is possible by numerical algorithms. Here we present a unified dispersion/aberration correction which is based on a polynomial parameterization of the phase error and an optimization of the image quality using Shannon’s entropy. For validation, a supercontinuum light sources and a costume-made spectrometer with 400 nm bandwidth were combined with a high NA microscope objective in a setup for tissue and small animal imaging. Using this setup and computation corrections, volumetric imaging at 1.5 μm resolution is possible. Cellular and near cellular resolution is demonstrated in porcine cornea and the drosophila larva, when computational correction of dispersion and aberrations is used. Due to the excellent correction of the used microscope objective, defocus was the main contribution to the aberrations. In addition, higher aberrations caused by the sample itself were successfully corrected. Dispersion and aberrations are closely related artifacts in microscopic OCT imaging. Hence they can be corrected in the same way by optimization of the image quality. This way microscopic resolution is easily achieved in OCT imaging of static biological tissues.},
keywords = {OCM},
pubstate = {published},
tppubtype = {inproceedings}
}
H. Schulz-Hildebrandt, M. Pieper, M. Ahrens, C. Idel, B. Wollenberg, P. König, and G. Hüttmann,
Novel endoscope with increased depth of field for imaging human nasal tissue by microscopic optical coherence tomography, Biomedical Optics Express , pp. 636-647, 2018.
DOI:10.1364/BOE.9.000636
Datei: abstract.cfm
Bibtex: BibTeX
@article{schulz2018novel,
title = {Novel endoscope with increased depth of field for imaging human nasal tissue by microscopic optical coherence tomography},
author = {Schulz-Hildebrandt, H; Pieper, M; Stehmar,C; Ahrens, M; Idel, C; Wollenberg,B; K\"{o}nig,P and Gereon H\"{u}ttmann},
editor = {Optic Socie Amer},
url = {https://www.osapublishing.org/abstract.cfm?URI=boe-9-2-636
https://www.osapublishing.org/boe/viewmedia.cfm?uri=boe-9-2-636&seq=0},
doi = {10.1364/BOE.9.000636},
isbn = {10.1364/BOE.9.000636},
year = {2018},
date = {2018-01-16},
journal = {Biomedical Optics Express},

pages = {636-647},
abstract = {Intravital microscopy (IVM) offers the opportunity to visualize static and dynamic changes of tissue on a cellular level. It is a valuable tool in research and may considerably improve clinical diagnosis. In contrast to confocal and non-linear microscopy, optical coherence tomography (OCT) with microscopic resolution (mOCT) provides intrinsically cross-sectional imaging. Changing focus position is not needed, which simplifies especially endoscopic imaging. For in-vivo imaging, here we are presenting endo-microscopic OCT (emOCT). A graded-index-lens (GRIN) based 2.75 mm outer diameter rigid endoscope is providing 1.5 \textendash 2 μm nearly isotropic resolution over an extended field of depth. Spherical and chromatic aberrations are used to elongate the focus length. Simulation of the OCT image formation, suggests overall a better image quality in this range compared to a focused Gaussian beam. Total imaging depth at a reduced sensitivity and lateral resolution is more than 200 μm. Using a frame rate of 80 Hz cross-sectional images of concha nasalis were demonstrated in humans, which could resolve cilial motion, cellular structures of the epithelium, vessels and blood cells. Mucus transport velocity was determined successfully. The endoscope may be used for diagnosis and treatment control of different lung diseases like cystic fibrosis or primary ciliary dyskinesia, which manifest already at the nasal mucosa.},
keywords = {Endoskope, OCM},
pubstate = {published},
tppubtype = {article}
}

2017

S. Kretschmer, M. Pieper, A. Klinger, G. Hüttmann, and P. König,
Imaging of Wound Closure of Small Epithelial Lesions in the Mouse Trachea, Am J Pathol , vol. 187, no. 11, pp. 2451-2460, Nov. 2017.
DOI:10.1016/j.ajpath.2017.07.006
Bibtex: BibTeX
@article{Kretschmer2017,
   author = {Kretschmer, S; Pieper, M; Klinger, A; Hüttmann, G. and König, P.},
   title = {Imaging of Wound Closure of Small Epithelial Lesions in the Mouse Trachea},
   journal = {Am J Pathol},
   ISSN = {0002-9440},
   DOI = {10.1016/j.ajpath.2017.07.006},
 
   year = {2017},
pages = {2451-2460},
   type = {Journal Article}
}
D. Hillmann, H. Spahr, C. Hain, L. Hinkel, G. Franke, and G. Hüttmann,
Off-axis reference beam for full-field swept-source OCT and holoscopy, Opt Expr , vol. 25, no. 22, pp. 27770-27784, Okt. 2017.
DOI:10.1364/OE.25.027770
Bibtex: BibTeX
@article{Hillmann2017,
   author = {Hillmann, D; Spahr, H; Sudkamp, H; Hain, C; Hinkel, L; Franke, G and Hüttmann, G},
   title = {Off-axis reference beam for full-field swept-source OCT and holoscopy},
   journal = {Opt Expr},
   
   pages = {27770-27784},
   DOI = {10.1364/OE.25.027770},
   year = {2017},
   type = {Journal Article}
}
C. Pfäffle, H. Spahr, D. Hillmann, H. Sudkamp, G. Franke, P. Koch, and G. Hüttmann,
Reduction of frame rate in full-field swept-source optical coherence tomography by numerical motion correction [Invited], Biomedical Optics Express , vol. 8, no. 3, pp. 1499-1511, 03 2017.
DOI:10.1364/BOE.8.001499
Weblink: https://doi.org/10.1364/BOE.8.001499
Datei: abstract.cfm
Bibtex: BibTeX
@article{Pfäffle2017,
   author = {Pfäffle, Clara and Spahr, Hendrik and Hillmann, Dierck and Sudkamp, Helge and Franke, Gesa and Koch, Peter and Hüttmann, Gereon},
   title = {Reduction of frame rate in full-field swept-source optical coherence tomography by numerical motion correction [Invited]},
   journal = {Biomedical Optics Express},
   volume = {8},
   number = {3},
   pages = {1499-1511},
   keywords = {Image reconstruction-restoration
Optical coherence tomography},
   url = {http://www.osapublishing.org/boe/abstract.cfm?URI=boe-8-3-1499},
   year = {2017},
   type = {Journal Article}
}
M. Casper, H. Schulz-Hildebrandt, M. Evers, C. Nguyen, G. Hüttmann, and D. Manstein,
Imaging cold-induced vasodynamic behaviour in skin using OCT for microangiography (Conference Presentation), in Proceedings Volume 10037, Photonics in Dermatology and Plastic Surgery , Spie, Eds. 2017.
DOI:doi: 10.1117/12.2251485
Bibtex: BibTeX
@conference{Casper2017,
title = {Imaging cold-induced vasodynamic behaviour in skin using OCT for microangiography (Conference Presentation)},
author = {Malte Casper and Hinnerk Schulz-Hildebrandt and Michael Evers and Cuc Nguyen and Reginald Birngruber and Gereon H\"{u}ttmann and Dieter Manstein},
editor = {Spie},
doi = {doi: 10.1117/12.2251485},
year = {2017},
date = {2017-04-19},
booktitle = {Proceedings Volume 10037, Photonics in Dermatology and Plastic Surgery},
volume = {10037OS},
abstract = {In dermatology the reflexes of vasoconstriction and vasodilation are known as important mechanisms of thermoregulation of the inner body. Imaging the physiology of microvasculature of the skin with high spatial resolution in three dimensions while reacting to changes in temperature is crucial for understanding the complex processes of vasodynamics, which result in constriction and dilation of vessels. However, previous studies using Laser-Doppler flowmetry and -imaging could not provide reliable angiographic images which allow to quantify changes in blood vessel diameter. Here, we report a different approach for angiographic imaging of microvasculature of a anaesthetized rodent model using speckle variance optical coherence tomography (svOCT) during and after localized cooling. Therefore a commercial OCT with a center wavelength of 1.3 μm and a spatial resolution of 13µm was used in combination with a custom built cooling device to image such reflexes at the mouse ear pinna and dorsal skinfold. Cooling was applied in steps of 2−5◦ C starting at the baseline temperature of 27◦ C down to −10◦ C. To our surprise and in contrast to the general opinion in literature, we were able to observe that the majority of vessels with a diameter larger than 20 μm maintain perfused with a constant diameter when the tissue is cooled from baseline to subzero temperatures. However, vasoconstriction was observed very rarely and only in veins, which led to their occlusion. The results of this experiment lead us to reconsider essential aspects of previous understanding of temperature-induced vasodynamics in cutaneous microvasculature.},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
C. Yao, F. Rudnitzki, G. Hüttmann, Z. Zhang, and R. Rahmanzadeh,
Important factors for cell-membrane permeabilization by gold nanoparticles activated by nanosecond-laser irradiation, International Journal of Nanomedicine , vol. 12, pp. 5659-5672, 2017.
DOI:10.2147/IJN.S140620
Bibtex: BibTeX
@article{Yao2017,
   author = {Yao, C; Rudnitzki, F; Hüttmann, G; Zhang, Zand Rahmanzadeh, R},
   title = {Important factors for cell-membrane permeabilization by gold nanoparticles activated by nanosecond-laser irradiation},
journal = {International Journal of Nanomedicine},
  
   pages = {5659-5672},
   DOI = {10.2147/IJN.S140620},
   year = {2017},
   type = {Journal Article}
}
C. Buj, M. Münter, B. Schmarbeck, J. Horstmann, G. Hüttmann, and R. Brinkmann,
Noncontact holographic detection for photoacoustic tomography, J Biomed Opt , vol. 22, no. 10, pp. 1-14, 2017.
DOI:10.1117/1.jbo.22.10.106007
Bibtex: BibTeX
@article{Buj2017,
   author = {Buj, C; Münter, M; Schmarbeck, B; Horstmann, J; Hüttmann, G and Brinkmann, R},
   title = {Noncontact holographic detection for photoacoustic tomography},
   journal = {J Biomed Opt},
   
   pages = {1-14},
   DOI = {10.1117/1.jbo.22.10.106007},
   year = {2017},
   type = {Journal Article}
}


2016

J. Horstmann, S. Siebelmann, I. Glasunow, A. Schadschneider, and G. Hüttmann,
OCT verstehen – Teil 2: Praktische Aspekte und Anwendung, Augenheilkunde up2date , vol. 6, no. 04, pp. 305-320, Nov. 2016.
DOI:10.1055/s-0042-117459
Bibtex: BibTeX
@article{Horstmann2016,
   author = {Horstmann, J. and Siebelmann, S. and Schulz-Hildebrandt, H. and Glasunow, I. and Schadschneider, A. and Hüttmann, G.},
   title = {OCT verstehen – Teil 2: Praktische Aspekte und Anwendung},
   journal = {Augenheilkunde up2date},
   volume = {6},
   number = {04},
   pages = {305-320},
   ISSN = {1616-9719},
   DOI = {10.1055/s-0042-117459},
   year = {2016},
   type = {Journal Article}
}
H. Sudkamp, P. Koch, H. Spahr, D. Hillmann, G. Franke, M. Münst, F. Reinholz, R. Birngruber, and G. Hüttmann,
In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography, Optics Letters , vol. 41, no. 21, pp. 4987-4990, Nov. 2016.
DOI:10.1364/OL.41.004987
Datei: abstract.cfm
Bibtex: BibTeX
@article{RN4897,
   author = {Sudkamp, Helge and Koch, Peter and Spahr, Hendrik and Hillmann, Dierck and Franke, Gesa and Münst, Michael and Reinholz, Fred and Birngruber, Reginald and Hüttmann, Gereon},
   title = {In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography},
   journal = {Optics Letters},
   volume = {41},
   number = {21},
   pages = {4987-4990},
   DOI = {10.1364/OL.41.004987},
   url = {http://ol.osa.org/abstract.cfm?URI=ol-41-21-4987},
   year = {2016},
   type = {Journal Article}
}
H. Spahr, D. Hillmann, C. Hain, C. Pfäffle, H. Sudkamp, G. Franke, P. Koch, and G. Hüttmann,
Darstellung von Blutfluss und Pulsation in retinalen Gefäßen mit Full-Field-Swept-Source-OCT, Klin Monatsbl Augenheilkd , vol. 233, no. 12, pp. 1324-1330, Okt. 2016.
DOI:10.1055/s-0042-120279
Bibtex: BibTeX
@article{Spahr2016,
   author = {Spahr, H. and Hillmann, D. and Hain, C. and Pfäffle, C. and Sudkamp, H. and Franke, G. and Koch, P. and Hüttmann, G.},
   title = {Darstellung von Blutfluss und Pulsation in retinalen Gefäßen mit Full-Field-Swept-Source-OCT},
   journal = {Klin Monatsbl Augenheilkd},
   volume = {233},
   number = {12},
   pages = {1324-1330},
   ISSN = {0023-2165},
   DOI = {10.1055/s-0042-120279},
   year = {2016},
   type = {Journal Article}
}
H. Schulz-Hildebrandt, M. Pieper, J. Kasper, N. Traulsen, M. Mall, P. König, and G. Hüttmann,
Towards automated evaluation of mucus transport measured by microscopic OCT (mOCT) during hypertonic saline treatment of Cystic Fibrosis, Pneumologie , vol. 70, no. 07, pp. 1-48, 07 2016.
DOI:10.1055/s-0036-1584651
Bibtex: BibTeX
@article{Schulz-Hildebrandt2016,
   author = {Schulz-Hildebrandt, H. and Pieper, M. and Kasper, J. and Traulsen, N. and Mall, M. and König, P. and Hüttmann, G.},
   title = {Towards automated evaluation of mucus transport measured by microscopic OCT (mOCT) during hypertonic saline treatment of Cystic Fibrosis},
   journal = {Pneumologie},
   volume = {70},
   number = {07},
   pages = {1-48},
   ISSN = {0934-8387},
   DOI = {10.1055/s-0036-1584651},
   year = {2016},
   type = {Journal Article}
}