2023
Noah
Heldt,
Cornelia
Holzhausen,
Martin
Ahrens,
Mario
Pieper,
Peter
König, and
Gereon
Hüttmann,
Improved image quality in dynamic OCT imaging of airway and lung tissue by reduced imaging time and machine learning based data evaluation, in Abstract Book 11th DZL Annual Meeting , 11th DZL Annual Meeting, Fürstenfeldbruck, 14–16 June 2023, Deutsches Zentrum für Lungenforschung e. V Geschäftsstelle Aulweg 130 35392 Gießen: DZL, 072023. pp. 357.
Improved image quality in dynamic OCT imaging of airway and lung tissue by reduced imaging time and machine learning based data evaluation, in Abstract Book 11th DZL Annual Meeting , 11th DZL Annual Meeting, Fürstenfeldbruck, 14–16 June 2023, Deutsches Zentrum für Lungenforschung e. V Geschäftsstelle Aulweg 130 35392 Gießen: DZL, 072023. pp. 357.
Weblink: | https://dzl.de/wp-content/uploads/2023/06/Abstract-Book_2023-2.pdf |
File: | Dateilink |
Anke
Leichtle,
Zuzana
Penxova,
Thorge
Kempin,
David
Leffers,
Martin
Ahrens,
Peter
König,
Ralf
Brinkmann,
Gereon
Hüttmann,
Karl-Ludwig
Bruchhage, and
Hinnerk
Schulz-Hildebrandt,
Dynamic Microscopic Optical Coherence Tomography as a New Diagnostic Tool for Otitis Media, Photonics , vol. 10, no. 6, 06 2023.
Dynamic Microscopic Optical Coherence Tomography as a New Diagnostic Tool for Otitis Media, Photonics , vol. 10, no. 6, 06 2023.
DOI: | 10.3390/photonics10060685 |
File: | 685 |
Bibtex: | ![]() @Article{photonics10060685, AUTHOR = {Leichtle, Anke and Penxova, Zuzana and Kempin, Thorge and Leffers, David and Ahrens, Martin and König, Peter and Brinkmann, Ralf and Hüttmann, Gereon and Bruchhage, Karl-Ludwig and Schulz-Hildebrandt, Hinnerk}, TITLE = {Dynamic Microscopic Optical Coherence Tomography as a New Diagnostic Tool for Otitis Media}, JOURNAL = {Photonics}, VOLUME = {10}, YEAR = {2023}, NUMBER = {6}, ARTICLE-NUMBER = {685}, URL = {https://www.mdpi.com/2304-6732/10/6/685}, ISSN = {2304-6732}, ABSTRACT = {Hypothesis: Otitis media (OM) can be successfully visualized and diagnosed by dynamic microscopic optical coherence tomography (dmOCT). Background: OM is one of the most common infectious diseases and, according to the WHO, one of the leading health problems with high mortality in developing countries. Despite intensive research, the only definitive treatment of therapy-refractory OM for decades has been the surgical removal of inflamed tissue. Thereby, the intra-operative diagnosis is limited to the surgeon’s visual impression. Supportive imaging modalities have been little explored and have not found their way into clinical application. Finding imaging techniques capable of identifying inflamed tissue intraoperatively, therefore, is of significant clinical relevance. Methods: This work investigated a modified version of optical coherence tomography with a microscopic resolution (mOCT) regarding its ability to differentiate between healthy and inflamed tissue. Despite its high resolution, the differentiation of single cells with mOCT is often impossible. A new form of mOCT termed dynamic mOCT (dmOCT) achieves cellular contrast using micro-movements within cells based on their metabolism. It was used in this study to establish correlative measurements with histology. Results: Using dmOCT, images with microscopic resolution were acquired on ex vivo tissue samples of chronic otitis media and cholesteatoma. Imaging with dmOCT allowed the visualization of specific and characteristic cellular and subcellular structures in the cross-sectional images, which can be identified only to a limited extent in native mOCT. Conclusion: We demonstrated for the first time a new marker-free visualization in otitis media based on intracellular motion using dmOCT.}, DOI = {10.3390/photonics10060685} } |
Alexander
Altmann,
Michel
Eden,
Gereon
Hüttmann,
Christian
Schell, and
Ramtin
Rahmanzadeh,
Porphyrin-based sensor films for monitoring food spoilage, Food Packaging and Shelf Life , vol. 38, pp. 101105, 06 2023.
Porphyrin-based sensor films for monitoring food spoilage, Food Packaging and Shelf Life , vol. 38, pp. 101105, 06 2023.
DOI: | https://doi.org/10.1016/j.fpsl.2023.101105 |
File: | S2214289423000820 |
Bibtex: | ![]() @article{ALTMANN2023101105, title = {Porphyrin-based sensor films for monitoring food spoilage}, journal = {Food Packaging and Shelf Life}, volume = {38}, pages = {101105}, year = {2023}, issn = {2214-2894}, doi = {https://doi.org/10.1016/j.fpsl.2023.101105}, url = {https://www.sciencedirect.com/science/article/pii/S2214289423000820}, author = {Alexander Altmann and Michel Eden and Gereon Hüttmann and Christian Schell and Ramtin Rahmanzadeh}, keywords = {Biogenic amines, Sensors, Fish freshness, Food safety, Porphyrin, Smart packaging}, abstract = {To increase food safety and to minimize food waste, it is interesting for the food industry and consumers to be able to determine food spoilage continuously and non-destructively. When food of animal origin is degraded, amines are released as protein breakdown products, which could be used to monitor the freshness of meat and fish. In this work, we introduce a porphyrin-based sensor foil aimed at the detection of biogenic amines. The sensor-porphyrin is formulated on mesoporous silica. Reactivity towards moderate humidity was eliminated by dispersion of the functionalized silica in polyethylene (PE), followed by thermal extrusion resulting in PE foils. After exposure to amines, the sensor foil changes its color irreversibly from green to red. The color change is accompanied by a pronounced shift of the fluorescence spectrum, which was used as a sensitive method to detect the degradation of fish products in model experiments. Titanium dioxide particles in the foil increased the detected fluorescence emission. Experiments with fish filets showed the applicability of the sensor foils in a real-life application by indicating the degree of spoilage after several days, while the microbial growth was depicted by total viable count. We anticipate that our sensor can be an integral part of smart food packages, helping to track the freshness of food during transport or storage.} } |
Sarah
Latus,
Sarah
Grube,
Tim
Eixmann,
Maximilian
Neidhardt,
Stefan
Gerlach,
Robin
Mieling,
Gereon
Hüttmann,
Matthias
Lutz, and
Alexander
Schlaefer,
A Miniature Dual-Fiber Probe for Quantitative Optical Coherence Elastography, IEEE Transactions on Biomedical Engineering , pp. 1-9, 05 2023.
A Miniature Dual-Fiber Probe for Quantitative Optical Coherence Elastography, IEEE Transactions on Biomedical Engineering , pp. 1-9, 05 2023.
DOI: | 10.1109/TBME.2023.3275539 |
Bibtex: | ![]() @ARTICLE{10122996, author={Latus, Sarah and Grube, Sarah and Eixmann, Tim and Neidhardt, Maximilian and Gerlach, Stefan and Mieling, Robin and Hüttmann, Gereon and Lutz, Matthias and Schlaefer, Alexander}, journal={IEEE Transactions on Biomedical Engineering}, title={A Miniature Dual-Fiber Probe for Quantitative Optical Coherence Elastography}, year={2023}, volume={}, number={}, pages={1-9}, doi={10.1109/TBME.2023.3275539}} |
Awanish P.
Singh,
Madita
Göb,
Martin
Ahrens,
Tim
Eixmann,
Hinnerk
Schulz-Hildebrandt,
Gereon
Hüttmann,
Robert
Huber, and
Maik
Rahlves,
Synchronous high-speed OCT imaging with sensor less brushless DC motor and FDML laser in a phase-locked loop, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII , Joseph A. Izatt and James G. Fujimoto, Eds. SPIE, 032023. pp. 1236703.
Synchronous high-speed OCT imaging with sensor less brushless DC motor and FDML laser in a phase-locked loop, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII , Joseph A. Izatt and James G. Fujimoto, Eds. SPIE, 032023. pp. 1236703.
DOI: | 10.1117/12.2652955 |
Bibtex: | ![]() @inproceedings{10.1117/12.2652955, author = {Awanish Pratap Singh and Madita G{\"o}b and Martin Ahrens and Tim Eixmann and Hinnerk Schulz-Hildebrandt and Gereon H{\"u}ttmann and Robert Huber and Maik Rahlves}, title = {{Synchronous high-speed OCT imaging with sensor less brushless DC motor and FDML laser in a phase-locked loop}}, volume = {12367}, booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII}, editor = {Joseph A. Izatt and James G. Fujimoto}, organization = {International Society for Optics and Photonics}, publisher = {SPIE}, pages = {1236703}, abstract = {High-speed endoscopic optical coherence tomography (OCT) imaging in the MHz range has shown great potential in various medical applications ranging from cancer screening to vascular disease monitoring. High-speed imaging always suffers from non-uniform rotational distortion (NURD) due to asynchronous motor rotation with the OCT system. Several research groups have previously attempted to solve this problem, using either an expensive motor with a sensor or numerical correction after data acquisition. However, both techniques pose challenges for practical use. Therefore, in this study, we use an inexpensive sensorless brushless DC motor with a Fourier domain mode-locked (FDML) laser-based MHz OCT system and try to resolve the problem of synchronization using three different modalities, (i) Slave-mode: The FDML frequency serves as a master frequency for the motor, which is phase-locked to the FDML frequency, (ii) Master-mode: The revolution trigger obtained from the motor’s back electromotive force (BEMF) signal serves as a trigger signal for the OCT imaging system, (iii) Both: Fully synchronized setup, where the motor rotation is synchronized with the laser and the imaging system is synchronized with the motor to achieve phase-stable OCT imaging. The first case slightly fluctuates in live preview and imaging due to the absence of a revolution trigger, while the second has varying motor speeds. Therefore, we use the third case to phase-lock the motor with FDML and get a distortion-free live preview and image acquisition. Finally, we demonstrate high-speed SS-OCT structural imaging (at 3.3 MHz A-scan rates) of a finger with a 16 mm diameter probe (at 40,000 rpm).}, keywords = {Optical Coherence Tomography, Endoscopy, FDML , Closed Loop Motor Control, NURD compensation, Brushless DC Motor, Back Electromotive Force}, year = {2023}, doi = {10.1117/12.2652955}, URL = {https://doi.org/10.1117/12.2652955} } |
Leo
Puyo,
Clara
Pfäffle,
Hendrik
Spahr,
Jonas
Franke,
Daniel
Bublitz,
Dierck
Hillmann, and
Gereon
Hüttmann,
Diffuse-illumination holographic optical coherence tomography, Opt. Express , vol. 31, no. 20, pp. 33500--33517, 2023. Optica Publishing Group.
Diffuse-illumination holographic optical coherence tomography, Opt. Express , vol. 31, no. 20, pp. 33500--33517, 2023. Optica Publishing Group.
DOI: | 10.1364/OE.498654 |
File: | abstract.cfm |
Bibtex: | ![]() @article{Puyo:23, author = {L\'{e}o Puyo and Clara Pf\"{a}ffle and Hendrik Spahr and Jonas Franke and Daniel Bublitz and Dierck Hillmann and Gereon H\"{u}ttmann}, journal = {Opt. Express}, keywords = {Fourier optics; Full field optical coherence tomography; Image quality; Imaging techniques; Spatial frequency; Spatial light modulators}, number = {20}, pages = {33500--33517}, publisher = {Optica Publishing Group}, title = {Diffuse-illumination holographic optical coherence tomography}, volume = {31}, month = {Sep}, year = {2023}, url = {https://opg.optica.org/oe/abstract.cfm?URI=oe-31-20-33500}, doi = {10.1364/OE.498654}, abstract = {Holographic optical coherence tomography (OCT) is a powerful imaging technique, but its ability to reveal low-reflectivity features is limited. In this study, we performed holographic OCT by incoherently averaging volumes with changing diffuse illumination of numerical aperture (NA) equal to the detection NA. While the reduction of speckle from singly scattered light is only modest, we discovered that speckle from multiply scattered light can be arbitrarily reduced, resulting in substantial improvements in image quality. This technique also offers the advantage of suppressing noises arising from spatial coherence, and can be implemented with a partially spatially incoherent light source for further mitigation of multiple scattering. Finally, we show that although holographic reconstruction capabilities are increasingly lost with decreasing spatial coherence, they can be retained over an axial range sufficient to standard OCT applications.}, } |
2022
Clara
Pfäffle,
Hendrik
Spahr,
Katharina
Gercke,
Leo
Puyo,
Svea
Höhl,
David
Melenberg,
Yoko
Miura,
Gereon
Hüttmann, and
Dierck
Hillmann,
Phase-Sensitive Measurements of Depth-Dependent Signal Transduction in the Inner Plexiform Layer, Frontiers in Medicine , vol. 9, 06 2022.
Phase-Sensitive Measurements of Depth-Dependent Signal Transduction in the Inner Plexiform Layer, Frontiers in Medicine , vol. 9, 06 2022.
DOI: | 10.3389/fmed.2022.885187 |
File: | fmed.2022.885187 |
Bibtex: | ![]() @article{RN5328, author = {Pfäffle, C;Spahr, H;Gercke, K;Puyo, L;Höhl, S;Melenberg, D;Miura, Y;Hüttmann, G and Hillmann, D}, title = {Phase-Sensitive Measurements of Depth-Dependent Signal Transduction in the Inner Plexiform Layer}, journal = {Frontiers in Medicine}, volume = {9}, ISSN = {2296-858X}, DOI = {10.3389/fmed.2022.885187}, keywords = {optoretinography, optical coherence tomography, phase-sensitive OCT, functional imaging, inner plexiform layer, retina}, url = {https://www.frontiersin.org/articles/10.3389/fmed.2022.885187}, year = {2022}, type = {Journal Article} } |
P
Musial,
Tabea
Kohlfaerber,
Martin
Ahrens,
Hinnerk
Schulz-Hildebrandt,
Philipp
Steven, and
Gereon
Hüttmann,
Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride, Translational Vision Science & Technology , vol. 11(5), pp. 28-28, 2022.
Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride, Translational Vision Science & Technology , vol. 11(5), pp. 28-28, 2022.
DOI: | 10.1167/tvst.11.5.28 |
File: | tvst.11.5.28 |
Bibtex: | ![]() @article{Musial-2022, author = {Musial, G;Kohlfaerber, T;Ahrens, M;Schulz-Hildebrandt, H;Steven, P and Hüttmann, G}, title = {Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride}, journal = {Translational Vision Science & Technology}, keywords = {toxicity; optical coherence tomography; benzalkonium chloride}, volume = {11(5)}, pages = {28-28}, ISSN = {2164-2591}, DOI = {10.1167/tvst.11.5.28}, url = {https://doi.org/10.1167/tvst.11.5.28}, year = {2022}, type = {Journal Article} } |
Tabea
Kohlfaerber,
Mario
Pieper,
Michael
Münter,
Cornelia
Holzhausen,
Martin
Ahrens,
Christian
Idel,
Ludwig
Bruchhage,
Anke
Leichtle,
Peter
König,
Gereon
Hüttmann, and
Hinnerk
Schulz-Hildebrandt,
Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways, Biomedical Optics Express , vol. 13 (6), pp. 3211-3223, 2022.
Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways, Biomedical Optics Express , vol. 13 (6), pp. 3211-3223, 2022.
DOI: | 10.1364/BOE.456104 |
Bibtex: | ![]() @article{Kohlfarber2022, author = {Kohlfaerber, T;Pieper, M;Münter, M;Holzhausen, C;Ahrens, M;Idel, C;Bruchhage, K-L;Leichtle, A;König, P;Hüttmann, G and Schulz-Hildebrandt, H}, title = {Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways}, journal = {Biomedical Optics Express}, volume = {13 (6)}, pages = {3211-3223}, DOI = {10.1364/BOE.456104}, year = {2022}, type = {Journal Article} } |
Claus
von der Burchard,
Helge
Sudkamp,
Jan
Tode,
Christoph
Ehlken,
K.
Purtskhvanidze,
Moritz
Moltmann,
B.
Heimes,
Peter
Koch,
Michael
Münst,
Malte
vom Endt,
Timo
Kepp,
Dirk
Theisen-Kunde,
Inke R.
König,
Gereon
Hüttmann, and
Johann
Roider,
Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study, BMJ Open , vol. 12, no. 6, pp. e055082, 2022.
Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study, BMJ Open , vol. 12, no. 6, pp. e055082, 2022.
DOI: | 10.1136/bmjopen-2021-055082 |
File: | e055082.abstract |
Bibtex: | ![]() @article{von-der-Burchardt2022, author = {von der Burchard, C;Sudkamp, H;Tode, J;Ehlken, C;Purtskhvanidze, K;Moltmann, M;Heimes, B;Koch, P;Münst, M;vom Endt, M;Kepp, T;Theisen-Kunde, D;König, I;Hüttmann, G and Roider, J}, title = {Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study}, journal = {BMJ Open}, volume = {12}, number = {6}, pages = {e055082}, DOI = {10.1136/bmjopen-2021-055082}, url = {http://bmjopen.bmj.com/content/12/6/e055082.abstract}, year = {2022}, type = {Journal Article} } |
2021
Clara
Pfäffle,
Hendrik
Spahr,
Katharina
Gercke,
Sazan
Burhan,
David
Melenberg,
Yoko
Miura,
Gereon
Hüttmann, and
Dierck
Hillmann,
Phase-sensitive measurements of depth dependent signal transduction in the inner plexiform layer, in SPIE BIOS , SPIE, 082021.
Phase-sensitive measurements of depth dependent signal transduction in the inner plexiform layer, in SPIE BIOS , SPIE, 082021.
DOI: | 10.1117/12.2577605 |
Bibtex: | ![]() @inproceedings{RN5321, author = {Pfäffle, C;Spahr, H;Gercke, K;Burhan, S;Melenberg, D;Miura, Y;Hüttmann, G and Hillmann, D}, title = {Phase-sensitive measurements of depth dependent signal transduction in the inner plexiform layer}, booktitle = {SPIE BiOS}, publisher = {SPIE}, volume = {11623}, url = {https://doi.org/10.1117/12.2577605}, type = {Conference Proceedings} } |
Hubertus
Hakert,
Matthias
Eibl,
Marie
Tillich,
Ralph
Pries,
Gereon
Hüttmann,
Ralf
Brinkmann,
Barbara
Wollenberg,
Ludwig
Bruchhage,
Sebastian
Karpf, and
Robert
Huber,
Time-encoded stimulated Raman scattering microscopy of tumorous human pharynx tissue in the fingerprint region from 1500–1800 cm-1, Optics Letters , vol. 46(14), no. 14, pp. 3456-3459, 07 2021.
Time-encoded stimulated Raman scattering microscopy of tumorous human pharynx tissue in the fingerprint region from 1500–1800 cm-1, Optics Letters , vol. 46(14), no. 14, pp. 3456-3459, 07 2021.
DOI: | 10.1364/OL.424726 |
Bibtex: | ![]() @article{Hakert2021, author = {H. Hakert, M. Eibl, M. Tillich, R.Pries, G. Hüttmann, R. Brinkmann, B. Wollenberg, K-L. Bruchhage, S. Karpf and R. Huber}, title = {Time-encoded stimulated Raman scattering microscopy of tumorous human pharynx tissue in the fingerprint region from 1500–1800 cm-1}, journal = {Optics Letters}, volume = {46(14)}, number = {14}, pages = {3456-3459}, keywords = {AG-Huber_NL, Clinical applications, Master oscillator power amplifiers, Optical coherence tomography, Raman scattering, Stimulated Raman scattering, Stimulated scattering}, DOI = {https://doi.org/10.1364/OL.424726}, year = {2021}, type = {Journal Article} } |
Tuula
Peñate Medina,
Jan Philip
Kolb,
Gereon
Hüttmann,
Robert
Huber,
Oula
Peñate Medina,
Naomi
Larsen,
Arianna
Ferrari,
Magdalena
Rafecas,
Mark
Ellrichmann,
Mariya S.
Pravdivtseva,
Mariia
Anikeeva,
Jana
Humbert,
Marcus
Both,
Jennifer
Hundt, and
Jan-Bernd
Hövener,
Imaging Inflammation - From Whole Body Imaging to Cellular Resolution, Frontiers in immunology , vol. 12, pp. 692222-692222, 06 2021.
Imaging Inflammation - From Whole Body Imaging to Cellular Resolution, Frontiers in immunology , vol. 12, pp. 692222-692222, 06 2021.
DOI: | 10.3389/fimmu.2021.692222 |
Bibtex: | ![]() @article{PenateMedina2021, author = {Peñate Medina, T;Kolb, J P;Hüttmann, G;Huber, R;Peñate Medina, O;Ha, L;Ulloa, P;Larsen, N;Ferrari, A;Rafecas, M;Ellrichmann, M;Pravdivtseva, M S.;Anikeeva, M;Humbert, J;Both, M;Hundt, J E. and Hövener, J-B}, title = {Imaging Inflammation - From Whole Body Imaging to Cellular Resolution}, journal = {Frontiers in immunology}, keywords = {AG-Huber, MRI, PET, SPECT, optical imaging, Optical coherence tomography (OCT), precision medicine, Two-Photon microscopy (TPM), hyperpolarization}, volume = {12}, pages = {692222-692222}, ISSN = {1664-3224}, DOI = {10.3389/fimmu.2021.692222}, url = {https://pubmed.ncbi.nlm.nih.gov/34248987 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264453/}, year = {2021}, type = {Journal Article} } |
Michael
Münter,
Mario
Pieper,
Tabea
Kohlfaerber,
Ernst
Bodenstorfer,
Martin
Ahrens,
Christian
Winter,
Robert
Huber,
Peter
König,
Gereon
Hüttmann, and
Hinnerk
Schulz-Hildebrandt,
Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast, Biomed. Opt. Express , vol. 12, pp. 6024-6039, 2021.
Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast, Biomed. Opt. Express , vol. 12, pp. 6024-6039, 2021.
DOI: | 10.1364/BOE.425001 |
Bibtex: | ![]() @article{Münter2021, author = {M. Münter, M. Pieper, T. Kohlfaerber, E. Bodenstorfer, M. Ahrens, C. Winter, R. Huber, P. König, G. Hüttmann and H. Schulz-Hildebrandt}, title = {Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast}, journal = {BiomedOptE}, volume = {12(10)}, Keywords = {CMOS cameras,Full field optical coherence tomography,High numerical aperture optics, Image processing,In vivo imaging,Medical imaging,Ag-Huber}, pages = {6024-6039}, DOI = {10.1364/BOE.425001}, year = {2021}, type = {Journal Article} } |
Martin
Ahrens,
Christian
Idel,
Peter
König,
Gereon
Hüttmann, and
Hinnerk
Schulz-Hildebrandt,
Voice coil based endomicroscopic optical coherence tomography probe for in vivo mucosa examination, in Endoscopic Microscopy XVI , Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter, Eds. SPIE, 2021.
Voice coil based endomicroscopic optical coherence tomography probe for in vivo mucosa examination, in Endoscopic Microscopy XVI , Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter, Eds. SPIE, 2021.
DOI: | 10.1117/12.2578787 |
File: | 12.2578787 |
Bibtex: | ![]() @inproceedings{10.1117/12.2578787, title = {Voice coil based endomicroscopic optical coherence tomography probe for in vivo mucosa examination}, author = {Martin Ahrens and Christian Idel and Peter K\"{o}nig and Gereon H\"{u}ttmann and Hinnerk Schulz-Hildebrandt}, editor = {Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter}, url = {https://doi.org/10.1117/12.2578787}, doi = {10.1117/12.2578787}, year = {2021}, date = {2021-01-01}, booktitle = {Endoscopic Microscopy XVI}, volume = {11620}, publisher = {SPIE}, organization = {International Society for Optics and Photonics}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } |
Felix
Hilge,
Michael
Evers,
Malte
Casper,
Joshua Zev
Glahn,
Weeranut Phothong
M.D.,
Garuna Kositratna
M.D.,
Hinnerk
Schulz-Hildebrandt,
Gereon
Hüttmann, and
Dieter Manstein
M.D.,
Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography, in Photonics in Dermatology and Plastic Surgery 2021 , Bernard Choi and Haishan Zeng, Eds. SPIE, 2021.
Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography, in Photonics in Dermatology and Plastic Surgery 2021 , Bernard Choi and Haishan Zeng, Eds. SPIE, 2021.
DOI: | 10.1117/12.2577822 |
File: | 12.2577822 |
Bibtex: | ![]() @inproceedings{10.1117/12.2577822, title = {Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography}, author = {Felix Hilge and Michael Evers and Malte Casper and Joshua Zev Glahn and Weeranut Phothong M.D. and Garuna Kositratna M.D. and Hinnerk Schulz-Hildebrandt and Gereon H\"{u}ttmann and Dieter Manstein M.D.}, editor = {Bernard Choi and Haishan Zeng}, url = {https://doi.org/10.1117/12.2577822}, doi = {10.1117/12.2577822}, year = {2021}, date = {2021-01-01}, booktitle = {Photonics in Dermatology and Plastic Surgery 2021}, volume = {11618}, publisher = {SPIE}, organization = {International Society for Optics and Photonics}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } |
Tabea
Kohlfaerber,
Mario
Pieper,
Peter
König,
Ramtin
Rahmanzadeh,
Gereon
Hüttmann, and
Hinnerk
Schulz-Hildebrandt,
Comparison between dynamic microscopic OCT and autofluorescence multiphoton microscopy for label-free analysis of murine trachea, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV , Joseph A Izatt and James G Fujimoto, Eds. SPIE, 2021.
Comparison between dynamic microscopic OCT and autofluorescence multiphoton microscopy for label-free analysis of murine trachea, in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV , Joseph A Izatt and James G Fujimoto, Eds. SPIE, 2021.
DOI: | 10.1117/12.2583811 |
File: | 12.2583811 |
Bibtex: | ![]() @inproceedings{10.1117/12.2583811, title = {Comparison between dynamic microscopic OCT and autofluorescence multiphoton microscopy for label-free analysis of murine trachea}, author = {Tabea Kohlfaerber and Michael M\"{u}nter and Mario Pieper and Peter K\"{o}nig and Ramtin Rahmanzadeh and Gereon H\"{u}ttmann and Hinnerk Schulz-Hildebrandt}, editor = {Joseph A Izatt and James G Fujimoto}, url = {https://doi.org/10.1117/12.2583811}, doi = {10.1117/12.2583811}, year = {2021}, date = {2021-01-01}, booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV}, volume = {11630}, publisher = {SPIE}, organization = {International Society for Optics and Photonics}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } |
Sonja
Jäckle,
Annkristin
Lange,
Veronica
Garcia-Vazquez,
Tim
Eixmann,
Florian
Matysiak,
Malte Maria
Sieren,
Marco
Horn,
Gereon
Hüttmann,
Hinnerk
Schulz-Hildebrandt,
Floris
Ernst,
Stefan
Heldmann,
Torben
Pätz, and
Tobias
Preusser,
Instrument localisation for endovascular aneurysm repair: Comparison of two methods based on tracking systems or using imaging, International Journal of Medical Robotics and Computer Assisted Surgery , vol. 17(6), no. 6, pp. e2327, 2021.
Instrument localisation for endovascular aneurysm repair: Comparison of two methods based on tracking systems or using imaging, International Journal of Medical Robotics and Computer Assisted Surgery , vol. 17(6), no. 6, pp. e2327, 2021.
DOI: | 10.1002/rcs.2327 |
Bibtex: | ![]() @article{Jackle2021, abstract = {Background: In endovascular aneuysm repair (EVAR) procedures, medical instruments are currently navigated with a two-dimensional imaging based guidance requiring X-rays and contrast agent. Methods: Novel approaches for obtaining the three-dimensional instrument positions are introduced. Firstly, a method based on fibre optical shape sensing, one electromagnetic sensor and a preoperative computed tomography (CT) scan is described. Secondly, an approach based on image processing using one 2D fluoroscopic image and a preoperative CT scan is introduced. Results: For the tracking based method, average errors from 1.81 to 3.13 mm and maximum errors from 3.21 to 5.46 mm were measured. For the image-based approach, average errors from 3.07 to 6.02 mm and maximum errors from 8.05 to 15.75 mm were measured. Conclusion: The tracking based method is promising for usage in EVAR procedures. For the image-based approach are applications in smaller vessels more suitable, since its errors increase with the vessel diameter.}, author = {J{\"{a}}ckle, Sonja and Lange, Annkristin and Garcia-Vazquez, Veronica and Eixmann, Tim and Matysiak, Florian and Sieren, Malte Maria and Horn, Marco and Schulz-Hildebrandt, Hinnerk and H{\"{u}}ttmann, Gereon and Ernst, Floris and Heldmann, Stefan and P{\"{a}}tz, Torben and Preusser, Tobias}, doi = {10.1002/rcs.2327}, file = {:Users/schulz-hildebrandt/Documents/Mendeley Desktop/J{\"{a}}ckle et al/International Journal of Medical Robotics and Computer Assisted Surgery/J{\"{a}}ckle et al. - 2021 - Instrument localisation for endovascular aneurysm repair Comparison of two methods based on tracking systems or.pdf:pdf}, issn = {1478596X}, journal = {International Journal of Medical Robotics and Computer Assisted Surgery}, keywords = {2D/3D registration,3D localisation,computer-assisted surgery,electromagnetic tracking system,endovascular procedures,fibre optical shape sensing}, number = {6}, pages = {e2327}, year = {2021}, title = {{Instrument localisation for endovascular aneurysm repair: Comparison of two methods based on tracking systems or using imaging}}, volume = {17} } |
Michel
Wunderlich,
Peter
Koch,
Helge
Sudkamp,
Michael
Münst,
Malte
Endt,
Moritz
Moltmann, and
Gereon
Hüttmann,
Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms, in Ophthalmic Technologies XXXI , Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker, Eds. SPIE, 2021. pp. 116231Q.
Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms, in Ophthalmic Technologies XXXI , Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker, Eds. SPIE, 2021. pp. 116231Q.
DOI: | 10.1117/12.2583030 |
File: | 12.2583030 |
Bibtex: | ![]() @inproceedings{10.1117/12.2583030, author = {Michel Wunderlich and Peter Koch and Helge Sudkamp and Michael M{\"u}nst and Malte vom Endt and Moritz Moltmann and Gereon H{\"u}ttmann}, title = {{Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms}}, volume = {11623}, booktitle = {Ophthalmic Technologies XXXI}, editor = {Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker}, organization = {International Society for Optics and Photonics}, publisher = {SPIE}, pages = {116231Q}, keywords = {Retinal motion tracking in Off-Axis Full-Field OCT by local analy, Michel Wunderlich, Medizinsches Laserzentrum Lübeck, motion tracking, eye tracking, off-axis full-field time-domain OCT, OCT, retina}, year = {2021}, doi = {10.1117/12.2583030}, URL = {https://doi.org/10.1117/12.2583030} } |
Hinnerk
Schulz-Hildebrandt,
Martin
Ahrens,
Elisa
Wilken,
Cornelia
Holzhausen,
Peter
König, and
Gereon
Hüttmann,
Endo-microscopic optical coherence tomography (emOCT) with dynamic contrast, in Endoscopic Microscopy XVI , Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter, Eds. SPIE, 2021.
Endo-microscopic optical coherence tomography (emOCT) with dynamic contrast, in Endoscopic Microscopy XVI , Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter, Eds. SPIE, 2021.
DOI: | 10.1117/12.2575733 |
File: | 12.2575733 |
Bibtex: | ![]() @inproceedings{10.1117/12.2575733, title = {Endo-microscopic optical coherence tomography (emOCT) with dynamic contrast}, author = {Hinnerk Schulz-Hildebrandt and Martin Ahrens and Michael M\"{u}nter and Elisa Wilken and Tabea Kohlf\"{a}rber and Cornelia Holzhausen and Peter K\"{o}nig and Gereon H\"{u}ttmann}, editor = {Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter}, url = {https://doi.org/10.1117/12.2575733}, doi = {10.1117/12.2575733}, year = {2021}, date = {2021-01-01}, booktitle = {Endoscopic Microscopy XVI}, volume = {11620}, publisher = {SPIE}, organization = {International Society for Optics and Photonics}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } |
Matteo Guiseppe
Cereda,
Y.G.M.
Douven,
Koorosh
Faridpooya,
Gereon
Hüttmann,
Tim
Eixmann,
Hinnerk
Schulz-Hildebrandt,
Gernot
Kronreif,
Saskia
van Romunde,
Maarten
Beelen, and
M D.
de Smet,
Clinical Evaluation of an Instrument-Integrated OCT-Based Distance Sensor for Robotic Vitreoretinal Surgery, Ophthalmology Science , vol. 1(4), pp. 100085, 2021.
Clinical Evaluation of an Instrument-Integrated OCT-Based Distance Sensor for Robotic Vitreoretinal Surgery, Ophthalmology Science , vol. 1(4), pp. 100085, 2021.
DOI: | https://doi.org/10.1016/j.xops.2021.100085 |
Bibtex: | ![]() @article{Cereda-2021, author = {Cereda, M G;Parrulli, S;Douven, Y. G. M.;Faridpooya, K;van Romunde, S;Hüttmann, G;Eixmann, T;Schulz-Hildebrandt, H;Kronreif, G;Beelen, M and de Smet, M D.}, title = {Clinical Evaluation of an Instrument-Integrated OCT-Based Distance Sensor for Robotic Vitreoretinal Surgery}, journal = {Ophthalmology Science}, volume = {1(4)}, pages = {100085}, ISSN = {2666-9145}, DOI = {https://doi.org/10.1016/j.xops.2021.100085}, year = {2021}, type = {Journal Article} } |
Sonja
Jäckle,
Tim
Eixmann,
Florian
Matysiak,
Malte Maria
Sieren,
Marco
Horn,
Hinnerk
Schulz-Hildebrandt,
Gereon
Hüttmann, and
Torben
Pätz,
3D Stent Graft Guidance based on Tracking Systems for Endovascular Aneurysm Repair, Current Directions in Biomedical Engineering , vol. 7(1), no. 1, pp. 17--20, 2021.
3D Stent Graft Guidance based on Tracking Systems for Endovascular Aneurysm Repair, Current Directions in Biomedical Engineering , vol. 7(1), no. 1, pp. 17--20, 2021.
DOI: | doi:10.1515/cdbme-2021-1004 |
File: | cdbme-2021-1004 |
Bibtex: | ![]() @article{Jaeckle2021c, author = {J{\"{a}}ckle, Sonja and Eixmann, Tim and Matysiak, Florian and Sieren, Malte Maria and Horn, Marco and Schulz-Hildebrandt, Hinnerk and H{\"{u}}ttmann, Gereon and P{\"{a}}tz, Torben}, doi = {doi:10.1515/cdbme-2021-1004}, journal = {Current Directions in Biomedical Engineering}, year = {2021}, number = {1}, pages = {17--20}, title = {{3D Stent Graft Guidance based on Tracking Systems for Endovascular Aneurysm Repair:}}, url = {https://doi.org/10.1515/cdbme-2021-1004}, volume = {7}, } |
2020
Claus
von der Burchard,
Moritz
Moltmann,
Jan
Tode,
Christoph
Ehlken,
Helge
Sudkamp,
Dirk
Theisen-Kunde,
Inke R.
König,
Gereon
Hüttmann, and
Johann
Roider,
Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases, Graefe's Archive for Clinical and Experimental Ophthalmology , Dec. 2020.
Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases, Graefe's Archive for Clinical and Experimental Ophthalmology , Dec. 2020.
File: | s00417-020-05035-6 |
Bibtex: | ![]() @article{von-derBurchard2020, author = {von der Burchard, C;Moltmann, M.;Tode, J;Ehlken, C;Sudkamp, H;Theisen-Kunde, D;König, I;Hüttmann, G and Roider, J}, title = {Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases}, journal = {Graefe's Archive for Clinical and Experimental Ophthalmology}, ISSN = {1435-702X}, url = {https://doi.org/10.1007/s00417-020-05035-6}, year = {2020}, type = {Journal Article} } |
Sonja
Jäckle,
Veronica
Garcia-Vazquez,
Tim
Eixmann,
Florian
Matysiak,
Felix
von Haxthausen,
Malte Maria
Sieren,
Hinnerk
Schulz-Hildebrandt,
Gereon
Hüttmann,
Floris
Ernst,
Markus
Kleemann, and
Torben
Pätz,
Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair, Int J Comp Assis Radiology and Surgery , 2020.
Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair, Int J Comp Assis Radiology and Surgery , 2020.
ISBN: | 1861-6429 |
File: | s11548-020-02167-2 |
Bibtex: | ![]() @article{jackle2020, title = {Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair}, author = {Jäckle,S; Garcia-Vazquez,V; Eixmann, T; Matysiak, F; von Haxthausen,F; Sieren; M m; Schulz-Hildebrandt, H; H\"{u}ttmann, G; Ernst, F; Kleemann, M and P\"{a}tz, T}, url = {https://doi.org/10.1007/s11548-020-02167-2}, isbn = {1861-6429}, year = {2020}, date = {2020-04-06}, journal = {Int J Comp Assis Radiology and Surgery}, abstract = {During endovascular aneurysm repair (EVAR) procedures, medical instruments are guided with two-dimensional (2D) fluoroscopy and conventional digital subtraction angiography. However, this requires X-ray exposure and contrast agent is used, and the depth information is missing. To overcome these drawbacks, a three-dimensional (3D) guidance approach based on tracking systems is introduced and evaluated.}, keywords = {HSH}, pubstate = {published}, tppubtype = {article} } |
Tobias
Fischer,
Antje
Klinger,
Dorthe
Smolinski,
Regina
Orzekowsky-Schröder,
Falk
Nitzsche,
Alfred
Vogel,
Gereon
Hüttmann, and
Andreas
Gebert,
High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , pp. 1-8, 2020.
High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , pp. 1-8, 2020.
File: | s00441-020-03167-z |
Bibtex: | ![]() @article{Fischer2020, author = {Fischer, T;Klinger, A;von Smolinski, D;Orzekowsky-Schroeder, R;Nitzsche, F;Bölke, T;Vogel, A;Hüttmann, G and Gebert, A}, title = {High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures}, journal = {Cell and Tissue Research}, pages = {1-8}, ISSN = {1432-0878}, url = {https://doi.org/10.1007/s00441-020-03167-z}, year = {2020}, type = {Journal Article} } |
Michael
Münter,
Mario
Pieper,
Malte
Casper,
Martin
Ahrens,
Tabea
Kohlfaerber,
Ramtin
Rahmanzadeh,
Peter
König,
Gereon
Hüttmann, and
Hinnerk
Schulz-Hildebrandt,
Dynamic contrast in scanning microscopic OCT, Optic Letters , 2020.
Dynamic contrast in scanning microscopic OCT, Optic Letters , 2020.
File: | 2003.00006 |
Bibtex: | ![]() @article{Münter2020, author = {Münter, M;Endt, M v;Pieper, M;Casper, M;Ahrens, M;Kohlfaerber, T;Rahmanzadeh, R;König, P;Hüttmann, G and Schulz-Hildebrandt, H}, title = {Dynamic contrast in scanning microscopic OCT}, journal = {Optic Letters}, url = {https://arxiv.org/abs/2003.00006}, year = {2020}, type = {Journal Article} } |
Vasily
Matkivsky,
Alexander
Moiseev,
Pavel
Shilyagin,
Alexander
Rodionov,
Hendrik
Spahr,
Clara
Pfäffle,
Gereon
Hüttmann,
Dierck
Hillmann, and
Grigory
Gelikonov,
Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function, Journal of Biophotonics , vol. 13(10), pp. e202000112, 2020.
Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function, Journal of Biophotonics , vol. 13(10), pp. e202000112, 2020.
DOI: | 10.1002/jbio.202000112 |
Bibtex: | ![]() @article{Matkivsky2020, author = {Matkivsky, V;Moiseev, A;Shilyagin, P;Rodionov, A;Spahr, H;Pfäffle, C;Hüttmann, G;Hillmann, D and Gelikonov, G}, title = {Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function}, journal = {Journal of Biophotonics}, volume = {13(10)}, pages = {e202000112}, ISSN = {1864-063X}, DOI = {10.1002/jbio.202000112}, year = {2020}, type = {Journal Article} } |
Cuiping
Yao,
Florian
Rudnitzki,
Yida
He,
Zhenxi
Zhang,
Gereon
Hüttmann, and
Ramtin
Rahmanzadeh,
Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods, JBio , 2020.
Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods, JBio , 2020.
DOI: | 10.1002/jbio.202000017 |
Bibtex: | ![]() @article{Rahmanzadeh-2020, author = {Yao, C;Rudnitzki, F;He, Y;Zhang, Z;Hüttmann, G and Rahmanzadeh, R}, title = {Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods}, journal = {JBio}, ISSN = {1864-063X}, DOI = {10.1002/jbio.202000017}, Year = {2020}, type = {Journal Article} } |
Hartmut
Schneider,
Martin
Ahrens,
Michaela
Strumpski,
Claudia
Rüger,
Matthias
Häfer,
Gereon
Hüttmann,
Dirk
Theisen-Kunde,
Hinnerk
Schulz-Hildebrandt, and
Rainer
Haak,
An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations, J Clin Med , vol. 9(10), 2020.
An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations, J Clin Med , vol. 9(10), 2020.
DOI: | 10.3390/jcm9103257 |
Bibtex: | ![]() @article{schneider2020, author = {Schneider, H.;Ahrens, M.;Strumpski, M.;Ruger, C.;Hafer, M.;Huettmann, G.;Theisen-Kunde, D.;Schulz-Hildebrandt, H. and Haak, R.}, title = {An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations}, journal = {J Clin Med}, volume = {9(10)}, keywords = {OCT; intraoral probe; carious lesions; caries diagnosis; dental restorations}, ISSN = {2077-0383 (Print) 2077-0383 (Linking)}, DOI = {10.3390/jcm9103257}, year = {2020}, type = {Journal Article} } |
Asylkhan E.
Rakhymzhan,
Lucie
Reuter,
Raphael
Raspe,
Daniel
Bremer,
Judith
Heidelin,
Volker
Andresen,
Robert
Günther,
Ruth
Leben,
Sergey
Cheremukhin,
Hinnerk
Schulz-Hildebrandt,
Maria G.
Bixel,
Ralf H.
Adams,
Helena
Radbruch,
Gereon
Hüttmann,
Anja E.
Hauser, and
Raluca A.
Niesner,
Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging, Cytometry Part A , vol. 97, no. 5, pp. 515-527, 2020.
Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging, Cytometry Part A , vol. 97, no. 5, pp. 515-527, 2020.
DOI: | 10.1002/cyto.a.24012 |
Bibtex: | ![]() @article{Schulz-Hildebrandt-2020, author = {Rakhymzhan, A;Reuter, L;Raspe, R;Bremer, D;Günther, R;Leben, R;Heidelin, J;Andresen, V;Cheremukhin, S;Schulz-Hildebrandt, H;Bixel, M G.;Adams, R H.;Radbruch, H;Hüttmann, G;Hauser, A E. and Niesner, R A.}, title = {Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging}, year = {2020}, journal = {Cytometry Part A}, volume = {97}, number = {5}, pages={515-527}, ISSN = {1552-4922}, DOI = {10.1002/cyto.a.24012}, type = {Journal Article} } |