2021
Sonja
Jäckle,
Annkristin
Lange,
Veronica
Garcia-Vazquez,
Tim
Eixmann,
Florian
Matysiak,
Malte Maria
Sieren,
Marco
Horn,
Gereon
Hüttmann,
Hinnerk
Schulz-Hildebrandt,
Floris
Ernst,
Stefan
Heldmann,
Torben
Pätz, and
Tobias
Preusser,
Instrument localisation for endovascular aneurysm repair: Comparison of two methods based on tracking systems or using imaging, International Journal of Medical Robotics and Computer Assisted Surgery , vol. 17(6), no. 6, pp. e2327, 2021.
Instrument localisation for endovascular aneurysm repair: Comparison of two methods based on tracking systems or using imaging, International Journal of Medical Robotics and Computer Assisted Surgery , vol. 17(6), no. 6, pp. e2327, 2021.
DOI: | 10.1002/rcs.2327 |
Bibtex: | ![]() @article{Jackle2021, abstract = {Background: In endovascular aneuysm repair (EVAR) procedures, medical instruments are currently navigated with a two-dimensional imaging based guidance requiring X-rays and contrast agent. Methods: Novel approaches for obtaining the three-dimensional instrument positions are introduced. Firstly, a method based on fibre optical shape sensing, one electromagnetic sensor and a preoperative computed tomography (CT) scan is described. Secondly, an approach based on image processing using one 2D fluoroscopic image and a preoperative CT scan is introduced. Results: For the tracking based method, average errors from 1.81 to 3.13 mm and maximum errors from 3.21 to 5.46 mm were measured. For the image-based approach, average errors from 3.07 to 6.02 mm and maximum errors from 8.05 to 15.75 mm were measured. Conclusion: The tracking based method is promising for usage in EVAR procedures. For the image-based approach are applications in smaller vessels more suitable, since its errors increase with the vessel diameter.}, author = {J{\"{a}}ckle, Sonja and Lange, Annkristin and Garcia-Vazquez, Veronica and Eixmann, Tim and Matysiak, Florian and Sieren, Malte Maria and Horn, Marco and Schulz-Hildebrandt, Hinnerk and H{\"{u}}ttmann, Gereon and Ernst, Floris and Heldmann, Stefan and P{\"{a}}tz, Torben and Preusser, Tobias}, doi = {10.1002/rcs.2327}, file = {:Users/schulz-hildebrandt/Documents/Mendeley Desktop/J{\"{a}}ckle et al/International Journal of Medical Robotics and Computer Assisted Surgery/J{\"{a}}ckle et al. - 2021 - Instrument localisation for endovascular aneurysm repair Comparison of two methods based on tracking systems or.pdf:pdf}, issn = {1478596X}, journal = {International Journal of Medical Robotics and Computer Assisted Surgery}, keywords = {2D/3D registration,3D localisation,computer-assisted surgery,electromagnetic tracking system,endovascular procedures,fibre optical shape sensing}, number = {6}, pages = {e2327}, year = {2021}, title = {{Instrument localisation for endovascular aneurysm repair: Comparison of two methods based on tracking systems or using imaging}}, volume = {17} } |
Michael
Münter,
Mario
Pieper,
Tabea
Kohlfaerber,
Ernst
Bodenstorfer,
Martin
Ahrens,
Christian
Winter,
Robert
Huber,
Peter
König,
Gereon
Hüttmann, and
Hinnerk
Schulz-Hildebrandt,
Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast, Biomed. Opt. Express , vol. 12, pp. 6024-6039, 2021.
Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast, Biomed. Opt. Express , vol. 12, pp. 6024-6039, 2021.
DOI: | 10.1364/BOE.425001 |
Bibtex: | ![]() @article{Münter2021, author = {M. Münter, M. Pieper, T. Kohlfaerber, E. Bodenstorfer, M. Ahrens, C. Winter, R. Huber, P. König, G. Hüttmann and H. Schulz-Hildebrandt}, title = {Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast}, journal = {BiomedOptE}, volume = {12(10)}, Keywords = {CMOS cameras,Full field optical coherence tomography,High numerical aperture optics, Image processing,In vivo imaging,Medical imaging,Ag-Huber}, pages = {6024-6039}, DOI = {10.1364/BOE.425001}, year = {2021}, type = {Journal Article} } |
Felix
Hilge,
Michael
Evers,
Malte
Casper,
Joshua Zev
Glahn,
Weeranut Phothong
M.D.,
Garuna Kositratna
M.D.,
Hinnerk
Schulz-Hildebrandt,
Gereon
Hüttmann, and
Dieter Manstein
M.D.,
Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography, in Photonics in Dermatology and Plastic Surgery 2021 , Bernard Choi and Haishan Zeng, Eds. SPIE, 2021.
Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography, in Photonics in Dermatology and Plastic Surgery 2021 , Bernard Choi and Haishan Zeng, Eds. SPIE, 2021.
DOI: | 10.1117/12.2577822 |
File: | 12.2577822 |
Bibtex: | ![]() @inproceedings{10.1117/12.2577822, title = {Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography}, author = {Felix Hilge and Michael Evers and Malte Casper and Joshua Zev Glahn and Weeranut Phothong M.D. and Garuna Kositratna M.D. and Hinnerk Schulz-Hildebrandt and Gereon H\"{u}ttmann and Dieter Manstein M.D.}, editor = {Bernard Choi and Haishan Zeng}, url = {https://doi.org/10.1117/12.2577822}, doi = {10.1117/12.2577822}, year = {2021}, date = {2021-01-01}, booktitle = {Photonics in Dermatology and Plastic Surgery 2021}, volume = {11618}, publisher = {SPIE}, organization = {International Society for Optics and Photonics}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } |
Martin
Ahrens,
Christian
Idel,
Peter
König,
Gereon
Hüttmann, and
Hinnerk
Schulz-Hildebrandt,
Voice coil based endomicroscopic optical coherence tomography probe for in vivo mucosa examination, in Endoscopic Microscopy XVI , Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter, Eds. SPIE, 2021.
Voice coil based endomicroscopic optical coherence tomography probe for in vivo mucosa examination, in Endoscopic Microscopy XVI , Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter, Eds. SPIE, 2021.
DOI: | 10.1117/12.2578787 |
File: | 12.2578787 |
Bibtex: | ![]() @inproceedings{10.1117/12.2578787, title = {Voice coil based endomicroscopic optical coherence tomography probe for in vivo mucosa examination}, author = {Martin Ahrens and Christian Idel and Peter K\"{o}nig and Gereon H\"{u}ttmann and Hinnerk Schulz-Hildebrandt}, editor = {Guillermo Tearney J M.D. and Thomas D Wang and Melissa J Suter}, url = {https://doi.org/10.1117/12.2578787}, doi = {10.1117/12.2578787}, year = {2021}, date = {2021-01-01}, booktitle = {Endoscopic Microscopy XVI}, volume = {11620}, publisher = {SPIE}, organization = {International Society for Optics and Photonics}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } |
2020
Claus
von der Burchard,
Moritz
Moltmann,
Jan
Tode,
Christoph
Ehlken,
Helge
Sudkamp,
Dirk
Theisen-Kunde,
Inke R.
König,
Gereon
Hüttmann, and
Johann
Roider,
Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases, Graefe's Archive for Clinical and Experimental Ophthalmology , Dec. 2020.
Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases, Graefe's Archive for Clinical and Experimental Ophthalmology , Dec. 2020.
File: | s00417-020-05035-6 |
Bibtex: | ![]() @article{von-derBurchard2020, author = {von der Burchard, C;Moltmann, M.;Tode, J;Ehlken, C;Sudkamp, H;Theisen-Kunde, D;König, I;Hüttmann, G and Roider, J}, title = {Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases}, journal = {Graefe's Archive for Clinical and Experimental Ophthalmology}, ISSN = {1435-702X}, url = {https://doi.org/10.1007/s00417-020-05035-6}, year = {2020}, type = {Journal Article} } |
Hartmut
Schneider,
Martin
Ahrens,
Michaela
Strumpski,
Claudia
Rüger,
Matthias
Häfer,
Gereon
Hüttmann,
Dirk
Theisen-Kunde,
Hinnerk
Schulz-Hildebrandt, and
Rainer
Haak,
An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations, J Clin Med , vol. 9(10), 2020.
An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations, J Clin Med , vol. 9(10), 2020.
DOI: | 10.3390/jcm9103257 |
Bibtex: | ![]() @article{schneider2020, author = {Schneider, H.;Ahrens, M.;Strumpski, M.;Ruger, C.;Hafer, M.;Huettmann, G.;Theisen-Kunde, D.;Schulz-Hildebrandt, H. and Haak, R.}, title = {An Intraoral OCT Probe to Enhanced Detection of Approximal Carious Lesions and Assessment of Restorations}, journal = {J Clin Med}, volume = {9(10)}, keywords = {OCT; intraoral probe; carious lesions; caries diagnosis; dental restorations}, ISSN = {2077-0383 (Print) 2077-0383 (Linking)}, DOI = {10.3390/jcm9103257}, year = {2020}, type = {Journal Article} } |
Cuiping
Yao,
Florian
Rudnitzki,
Yida
He,
Zhenxi
Zhang,
Gereon
Hüttmann, and
Ramtin
Rahmanzadeh,
Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods, JBio , 2020.
Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods, JBio , 2020.
DOI: | 10.1002/jbio.202000017 |
Bibtex: | ![]() @article{Rahmanzadeh-2020, author = {Yao, C;Rudnitzki, F;He, Y;Zhang, Z;Hüttmann, G and Rahmanzadeh, R}, title = {Cancer cell-specific protein delivery by optoporation with laser-irradiated gold nanorods}, journal = {JBio}, ISSN = {1864-063X}, DOI = {10.1002/jbio.202000017}, Year = {2020}, type = {Journal Article} } |
Asylkhan E.
Rakhymzhan,
Lucie
Reuter,
Raphael
Raspe,
Daniel
Bremer,
Judith
Heidelin,
Volker
Andresen,
Robert
Günther,
Ruth
Leben,
Sergey
Cheremukhin,
Hinnerk
Schulz-Hildebrandt,
Maria G.
Bixel,
Ralf H.
Adams,
Helena
Radbruch,
Gereon
Hüttmann,
Anja E.
Hauser, and
Raluca A.
Niesner,
Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging, Cytometry Part A , vol. 97, no. 5, pp. 515-527, 2020.
Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging, Cytometry Part A , vol. 97, no. 5, pp. 515-527, 2020.
DOI: | 10.1002/cyto.a.24012 |
Bibtex: | ![]() @article{Schulz-Hildebrandt-2020, author = {Rakhymzhan, A;Reuter, L;Raspe, R;Bremer, D;Günther, R;Leben, R;Heidelin, J;Andresen, V;Cheremukhin, S;Schulz-Hildebrandt, H;Bixel, M G.;Adams, R H.;Radbruch, H;Hüttmann, G;Hauser, A E. and Niesner, R A.}, title = {Coregistered Spectral Optical Coherence Tomography and Two-Photon Microscopy for Multimodal Near-Instantaneous Deep-Tissue Imaging}, year = {2020}, journal = {Cytometry Part A}, volume = {97}, number = {5}, pages={515-527}, ISSN = {1552-4922}, DOI = {10.1002/cyto.a.24012}, type = {Journal Article} } |
Vasily
Matkivsky,
Alexander
Moiseev,
Pavel
Shilyagin,
Alexander
Rodionov,
Hendrik
Spahr,
Clara
Pfäffle,
Gereon
Hüttmann,
Dierck
Hillmann, and
Grigory
Gelikonov,
Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function, Journal of Biophotonics , vol. 13(10), pp. e202000112, 2020.
Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function, Journal of Biophotonics , vol. 13(10), pp. e202000112, 2020.
DOI: | 10.1002/jbio.202000112 |
Bibtex: | ![]() @article{Matkivsky2020, author = {Matkivsky, V;Moiseev, A;Shilyagin, P;Rodionov, A;Spahr, H;Pfäffle, C;Hüttmann, G;Hillmann, D and Gelikonov, G}, title = {Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function}, journal = {Journal of Biophotonics}, volume = {13(10)}, pages = {e202000112}, ISSN = {1864-063X}, DOI = {10.1002/jbio.202000112}, year = {2020}, type = {Journal Article} } |
Michael
Münter,
Mario
Pieper,
Malte
Casper,
Martin
Ahrens,
Tabea
Kohlfaerber,
Ramtin
Rahmanzadeh,
Peter
König,
Gereon
Hüttmann, and
Hinnerk
Schulz-Hildebrandt,
Dynamic contrast in scanning microscopic OCT, Optic Letters , 2020.
Dynamic contrast in scanning microscopic OCT, Optic Letters , 2020.
File: | 2003.00006 |
Bibtex: | ![]() @article{Münter2020, author = {Münter, M;Endt, M v;Pieper, M;Casper, M;Ahrens, M;Kohlfaerber, T;Rahmanzadeh, R;König, P;Hüttmann, G and Schulz-Hildebrandt, H}, title = {Dynamic contrast in scanning microscopic OCT}, journal = {Optic Letters}, url = {https://arxiv.org/abs/2003.00006}, year = {2020}, type = {Journal Article} } |
Tobias
Fischer,
Antje
Klinger,
Dorthe
Smolinski,
Regina
Orzekowsky-Schröder,
Falk
Nitzsche,
Alfred
Vogel,
Gereon
Hüttmann, and
Andreas
Gebert,
High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , pp. 1-8, 2020.
High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , pp. 1-8, 2020.
File: | s00441-020-03167-z |
Bibtex: | ![]() @article{Fischer2020, author = {Fischer, T;Klinger, A;von Smolinski, D;Orzekowsky-Schroeder, R;Nitzsche, F;Bölke, T;Vogel, A;Hüttmann, G and Gebert, A}, title = {High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures}, journal = {Cell and Tissue Research}, pages = {1-8}, ISSN = {1432-0878}, url = {https://doi.org/10.1007/s00441-020-03167-z}, year = {2020}, type = {Journal Article} } |
Sonja
Jäckle,
Veronica
Garcia-Vazquez,
Tim
Eixmann,
Florian
Matysiak,
Felix
von Haxthausen,
Malte Maria
Sieren,
Hinnerk
Schulz-Hildebrandt,
Gereon
Hüttmann,
Floris
Ernst,
Markus
Kleemann, and
Torben
Pätz,
Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair, Int J Comp Assis Radiology and Surgery , 2020.
Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair, Int J Comp Assis Radiology and Surgery , 2020.
ISBN: | 1861-6429 |
File: | s11548-020-02167-2 |
Bibtex: | ![]() @article{jackle2020, title = {Three-dimensional guidance including shape sensing of a stentgraft system for endovascular aneurysm repair}, author = {Jäckle,S; Garcia-Vazquez,V; Eixmann, T; Matysiak, F; von Haxthausen,F; Sieren; M m; Schulz-Hildebrandt, H; H\"{u}ttmann, G; Ernst, F; Kleemann, M and P\"{a}tz, T}, url = {https://doi.org/10.1007/s11548-020-02167-2}, isbn = {1861-6429}, year = {2020}, date = {2020-04-06}, journal = {Int J Comp Assis Radiology and Surgery}, abstract = {During endovascular aneurysm repair (EVAR) procedures, medical instruments are guided with two-dimensional (2D) fluoroscopy and conventional digital subtraction angiography. However, this requires X-ray exposure and contrast agent is used, and the depth information is missing. To overcome these drawbacks, a three-dimensional (3D) guidance approach based on tracking systems is introduced and evaluated.}, keywords = {HSH}, pubstate = {published}, tppubtype = {article} } |
2019
Marco
Horn,
Sonja
Jäckle,
Felix
von Haxthausen,
Tim
Eixmann,
Hinnerk
Schulz-Hildebrandt,
Gereon
Hüttmann,
Juljan
Bouchagiar,
Florian
Matysiak,
Mark
Kaschwich,
Markus
Kleemann,
Floris
Ernst,
Veronica
Garcia-Vazquez, and
Torben
Pätz,
First Steps into Catheter Guidance Including Shape Sensing for Endovascular Aneurysm Repair Procedures, European Journal of Vascular and Endovascular Surgery , vol. 58, no. 6, pp. e610--e611, Dec. 2019. W.B. Saunders.
First Steps into Catheter Guidance Including Shape Sensing for Endovascular Aneurysm Repair Procedures, European Journal of Vascular and Endovascular Surgery , vol. 58, no. 6, pp. e610--e611, Dec. 2019. W.B. Saunders.
DOI: | 10.1016/J.EJVS.2019.09.091 |
Bibtex: | ![]() @proceedings{Horn2019b, title = {First Steps into Catheter Guidance Including Shape Sensing for Endovascular Aneurysm Repair Procedures}, author = {Marco Horn and Sonja J\"{a}ckle and Felix von Haxthausen and Tim Eixmann and Hinnerk Schulz-Hildebrandt and Gereon H\"{u}ttmann and Juljan Bouchagiar and Florian Matysiak and Mark Kaschwich and Markus Kleemann and Floris Ernst and Ver\'{o}nica Garc\'{i}a-V\'{a}zquez and Torben P\"{a}tz}, doi = {10.1016/J.EJVS.2019.09.091}, issn = {1078-5884}, year = {2019}, date = {2019-12-13}, journal = {European Journal of Vascular and Endovascular Surgery}, volume = {58}, number = {6}, pages = {e610--e611}, publisher = {W.B. Saunders}, keywords = {Sensing, Fiber}, pubstate = {published}, tppubtype = {proceedings} } |
Hendrik
Spahr,
Clara
Pfäffle,
Sazan
Burhan,
Lisa
Kutzner,
Felix
Hilge,
Gereon
Hüttmann, and
Dierck
Hillmann,
Phase-sensitive interferometry of decorrelated speckle patterns, Scientific report , vol. 9, Aug. 2019.
Phase-sensitive interferometry of decorrelated speckle patterns, Scientific report , vol. 9, Aug. 2019.
DOI: | 10.1038/s41598-019-47979-8 |
Bibtex: | ![]() @article{RN5217, author = {Spahr, Hendrik;Pfäffle, Clara;Burhan, Sazan;Kutzner, Lisa;Hilge, Felix;Hüttmann, Gereon and Hillmann, Dierck}, title = {Phase-sensitive interferometry of decorrelated speckle patterns}, journal = {Scientific Reports}, volume = {9}, number = {1}, pages = {11748}, ISSN = {2045-2322}, DOI = {10.1038/s41598-019-47979-8}, url = {https://doi.org/10.1038/s41598-019-47979-8}, year = {2019}, type = {Journal Article} } |
Hendrik
Spahr,
Clara
Pfäffle,
Gereon
Hüttmann, and
Dierck
Hillmann,
Artifacts in speckle tracking and multi-aperture Doppler OCT imaging of lateral motion, Opt. Lett. , vol. 44, no. 6, pp. 1315--1318, Mar. 2019. Optica Publishing Group.
Artifacts in speckle tracking and multi-aperture Doppler OCT imaging of lateral motion, Opt. Lett. , vol. 44, no. 6, pp. 1315--1318, Mar. 2019. Optica Publishing Group.
DOI: | 10.1364/OL.44.001315 |
File: | abstract.cfm |
Bibtex: | ![]() @article{RN5085, author = {Spahr, H;Pfäffle, C;Hüttmann, G and Hillmann, D}, title = {Artifacts in speckle tracking and multi-aperture Doppler OCT imaging of lateral motion}, journal = {Optics letters}, volume = {44(5)}, pages = {1315-1318}, DOI = {https://doi.org/10.1364/OL.44001315}, url = {https://doi.org/10.1364/OL.44001315}, year = {2019}, type = {Journal Article} } |
Dierck
Hillmann,
Clara
Pfäffle,
Hendrik
Spahr,
Sazan
Burhan,
Lisa
Kutzner,
Felix
Hilge, and
Gereon
Hüttmann,
Computational adaptive optics for optical coherence tomography using multiple randomized subaperture correlations, Opt Lett 44 (15) , pp. 3905-3908, 2019.
Computational adaptive optics for optical coherence tomography using multiple randomized subaperture correlations, Opt Lett 44 (15) , pp. 3905-3908, 2019.
DOI: | 10.1364/OL.44.003905 |
File: | 31368998 |
Bibtex: | ![]() @article{Hillmann2019, author = {Hillmann, D.;Pfaffle, C.;Spahr, H.;Burhan, S.;Kutzner, L.;Hilge, F. and Hüttmann, G.}, title = {Computational adaptive optics for optical coherence tomography using multiple randomized subaperture correlations}, journal = {Opt Lett 44 (15)}, pages = {3905-3908}, ISSN = {1539-4794 (Electronic) 0146-9592 (Linking)}, DOI = {10.1364/OL.44.003905}, url = {https://www.ncbi.nlm.nih.gov/pubmed/31368998}, year = {2019}, type = {Journal Article} } |
Tobias
Fischer,
Antje
Klinger,
Dorthe
Smolinski,
Regina
Orzekowsky-Schroeder,
Falk
Nitzsche,
Alfred
Vogel,
Gereon
Hüttmann, and
Andreas
Gebert,
High-resolution imaging of the living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , 2019.
High-resolution imaging of the living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , 2019.
Dierck
Hillmann,
Clara
Pfäffle,
Hendrik
Spahr,
Helge
Sudkamp,
Gesa
Franke, and
Gereon
Hüttmann,
In Vivo FF-SS-OCT Optical Imaging of Physiological Responses to Photostimulation of Human Photoreceptor Cells, in High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics , Bille, Josef F., Eds. Cham: Springer International Publishing, 2019, pp. 181-194.
In Vivo FF-SS-OCT Optical Imaging of Physiological Responses to Photostimulation of Human Photoreceptor Cells, in High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics , Bille, Josef F., Eds. Cham: Springer International Publishing, 2019, pp. 181-194.
ISBN: | 978-3-030-16638-0 |
File: | 978-3-030-16638-0_8 |
Bibtex: | ![]() @inbook{Hillmann2019, author = {Hillmann, Dierck;Pfäffle, Clara;Spahr, Hendrik;Sudkamp, Helge;Franke, Gesa and Hüttmann, Gereon}, title = {In Vivo FF-SS-OCT Optical Imaging of Physiological Responses to Photostimulation of Human Photoreceptor Cells}, booktitle = {High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics}, editor = {Bille, Josef F.}, publisher = {Springer International Publishing}, address = {Cham}, pages = {181-194}, ISBN = {978-3-030-16638-0}, url = {https://doi.org/10.1007/978-3-030-16638-0_8}, year = {2019}, type = {Book Section} } |
Tabea
Kohlfaerber,
Ding
Shujun,
Ramtin
Rahmanzadeh,
Thomas
Jüngst,
Jürgen
Groll,
Hinnerk
Schulz-Hildebrandt, and
Gereon
Hüttmann,
Investigation of cell dynamics in 3D cell spheroids and cell interaction with 3D printed scaffolds by mOCT, Transactions on Additive Manufacturing Meets Medicine 1(1) , 2019.
Investigation of cell dynamics in 3D cell spheroids and cell interaction with 3D printed scaffolds by mOCT, Transactions on Additive Manufacturing Meets Medicine 1(1) , 2019.
DOI: | 10.18416/AMMM.2019.1909S03P19 |
Bibtex: | ![]() @article{Kohlfärber2019, author = {Kohlfaerber, T;Ding, S;Rahmanzadeh, R;Jüngst, T;Groll, J;Schulz-Hildebrandt, H and Hüttmann, G}, title = {Investigation of cell dynamics in 3D cell spheroids and cell interaction with 3D printed scaffolds by mOCT}, journal = {Transactions on Additive Manufacturing Meets Medicine 1(1)}, DOI = {10.18416/AMMM.2019.1909S03P19}, year = {2019}, type = {Journal Article} } |
Timo
Kepp,
Christine
Droigk,
Malte
Casper,
Michael
Evers,
Gereon
Hüttmann,
Nunciada
Salma,
Dieter
Manstein,
Matthias P.
Heinrich, and
Heinz
Handels,
Segmentation of mouse skin layers in optical coherence tomography image data using deep convolutional neural networks, Biomed Opt Expr 10(7) , pp. 3484-3496, 2019.
Segmentation of mouse skin layers in optical coherence tomography image data using deep convolutional neural networks, Biomed Opt Expr 10(7) , pp. 3484-3496, 2019.
DOI: | 10.1364/BOE.10.003484 |
File: | BOE.10.003484 |
Bibtex: | ![]() @article{Hüttmann2019, author = {Kepp, T;Droigk, C;Casper, M;Evers, M;Hüttmann, G;Salma, N;Manstein, D;Heinrich, M P. and Handels, H}, title = {Segmentation of mouse skin layers in optical coherence tomography image data using deep convolutional neural networks}, journal = {Biomed Opt Expr 10(7)}, pages = {3484-3496}, DOI = {10.1364/BOE.10.003484}, url = {https://doi.org/10.1364/BOE.10.003484}, year = {2019}, type = {Journal Article} } |
Clara
Pfäffle,
Hendrik
Spahr,
Lisa
Kutzner,
Sazan
Burhan,
Felix
Hilge,
Yoko
Miura,
Gereon
Hüttmann, and
Dierck
Hillmann,
Simultaneous functional imaging of neuronal and photoreceptor layers in living human retina, Optics Letters 44(23) , pp. 5671-5674, 2019.
Simultaneous functional imaging of neuronal and photoreceptor layers in living human retina, Optics Letters 44(23) , pp. 5671-5674, 2019.
DOI: | 10.1364/OL.44.005671 |
Bibtex: | ![]() @article{Pfäffle2019, author = {Pfäffle, C;Spahr, H;Kutzner, L;Burhan, S;Hilge, F;Miura, Y;Hüttmann, G and Hillmann, D}, title = {Simultaneous functional imaging of neuronal and photoreceptor layers in living human retina}, journal = {Optics Letters 44(23)}, pages = {5671-5674}, DOI = {10.1364/OL.44.005671}, year = {2019}, type = {Journal Article} } |
Ramtin
Rahmanzadeh,
Florian
Rudnitzki, and
Gereon
Hüttmann,
Two ways to inactivate the Ki-67 protein—Fragmentation by nanoparticles, crosslinking with fluorescent dyes, Journal of Biophotonics , pp. e201800460, 2019.
Two ways to inactivate the Ki-67 protein—Fragmentation by nanoparticles, crosslinking with fluorescent dyes, Journal of Biophotonics , pp. e201800460, 2019.
DOI: | 10.1002/jbio.201800460 |
File: | jbio.201800460 |
Bibtex: | ![]() @article{Rahmanzadeh-2019, author = {Rahmanzadeh, R;Rudnitzki, F and Hüttmann, G}, title = {Two ways to inactivate the Ki-67 protein—Fragmentation by nanoparticles, crosslinking with fluorescent dyes}, journal = {Journal of Biophotonics}, Year = {2019}, pages = {e201800460}, ISSN = {1864-063X}, DOI = {10.1002/jbio.201800460}, url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201800460}, type = {Journal Article} } |
2018
Hinnerk
Schulz-Hildebrandt,
Tom
Pfeiffer,
Tim
Eixmann,
Sabrina
Lohmann,
Martin
Ahrens,
Josua
Rehra,
Wolfgang
Draxinger,
Peter
König,
Robert
Huber, and
Gereon
Hüttmann,
High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography, Opt. Lett. , vol. 43, no. 18, pp. 4386-4389, Sep. 2018. Optica Publishing Group.
High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography, Opt. Lett. , vol. 43, no. 18, pp. 4386-4389, Sep. 2018. Optica Publishing Group.
DOI: | 10.1364/OL.43.004386 |
Bibtex: | ![]() @article{Schulz-Hildebrandt:18, author = {Hinnerk Schulz-Hildebrandt and Tom Pfeiffer and Tim Eixmann and Sabrina Lohmann and Martin Ahrens and Joshua Rehra and Wolfgang Draxinger and Peter K\"{o}nig and Robert Huber and Gereon H\"{u}ttmann}, journal = {Opt. Lett.}, keywords = {Fiber optics imaging; Endoscopic imaging; Medical and biological imaging; Optical coherence tomography; Fourier domain mode locking; Image quality; Optical coherence tomography; Single mode fibers; Step index fibers; Three dimensional imaging}, number = {18}, pages = {4386--4389}, publisher = {Optica Publishing Group}, title = {High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography}, volume = {43}, month = {Sep}, year = {2018}, url = {https://opg.optica.org/ol/abstract.cfm?URI=ol-43-18-4386}, doi = {10.1364/OL.43.004386}, abstract = {We present a forward-viewing fiber scanning endoscope (FSE) for high-speed volumetric optical coherence tomography (OCT). The reduction in size of the probe was achieved by substituting the focusing optics by an all-fiber-based imaging system which consists of a combination of scanning single-mode fibers, a glass spacer, made from a step-index multi-mode fiber, and a gradient-index fiber. A lateral resolution of 11 $\mu$m was achieved at a working distance of 1.2 mm. The newly designed piezo-based FSE has an outer diameter of 1.6 mm and a rigid length of 13.5 mm. By moving the whole imaging optic in spirals for scanning the sample, the beam quality remains constant over the entire field of view with a diameter of 0.8 mm. The scanning frequency was adjusted to 1.22 kHz for use with a 3.28 MHz Fourier domain mode locked OCT system. Densely sampled volumes have been imaged at a rate of 6 volumes per second.}, } |
Helge
Sudkamp,
Dierck
Hillmann,
Peter
Koch,
Malte
vom Endt,
Hendrik
Spahr,
Michael
Münst,
Clara
Pfäffle,
Reginald
Birngruber, and
Gereon
Hüttmann,
Simple approach for aberration-corrected OCT imaging of the human retina, Opt Lett , vol. 43, no. 17, pp. 4224, Aug. 2018.
Simple approach for aberration-corrected OCT imaging of the human retina, Opt Lett , vol. 43, no. 17, pp. 4224, Aug. 2018.
DOI: | 10.1364/ol.43.004224 |
Bibtex: | ![]() @article{Sudkamp2018a, author = {Sudkamp, H; Hillmann, D; Koch, P;vom Endt, M; Spahr, H; Münst, M; Pfäffle, C; Birngruber, R and Hüttmann, G}, title = {Simple approach for aberration-corrected OCT imaging of the human retina}, journal = {Opt Lett}, pages = {4224}, ISSN = {0146-9592 1539-4794}, DOI = {10.1364/ol.43.004224}, year = {2018}, type = {Journal Article}, keyword = {Retome} } |
Hinnerk
Schulz-Hildebrandt,
Michael
Münter,
Martin
Ahrens,
Hendrik
Spahr,
Dierck
Hillmann,
Peter
König, and
Gereon
Hüttmann,
Coherence and diffraction limited resolution in microscopic OCT by a unified approach for the correction of dispersion and aberrations, in 2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources , 2018. pp. 105910O.
Coherence and diffraction limited resolution in microscopic OCT by a unified approach for the correction of dispersion and aberrations, in 2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources , 2018. pp. 105910O.
DOI: | 10.1117/12.2303755 |
ISBN: | 9781510616745 |
Bibtex: | ![]() @inproceedings{Schulz-Hildebrandt2018a, title = {Coherence and diffraction limited resolution in microscopic OCT by a unified approach for the correction of dispersion and aberrations}, author = {Schulz-Hildebrandt,H; M\"{u}nter, M; Ahrens,M; Spahr, H; Hillmann, D; K\"{o}nig, P and H\"{u}ttmann, G}, doi = {10.1117/12.2303755}, isbn = {9781510616745}, year = {2018}, date = {2018-03-05}, booktitle = {2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources}, volume = {10591}, pages = {105910O}, abstract = {Optical coherence tomography (OCT) images scattering tissues with 5 to 15 μm resolution. This is usually not sufficient for a distinction of cellular and subcellular structures. Increasing axial and lateral resolution and compensation of artifacts caused by dispersion and aberrations is required to achieve cellular and subcellular resolution. This includes defocus which limit the usable depth of field at high lateral resolution. OCT gives access the phase of the scattered light and hence correction of dispersion and aberrations is possible by numerical algorithms. Here we present a unified dispersion/aberration correction which is based on a polynomial parameterization of the phase error and an optimization of the image quality using Shannon’s entropy. For validation, a supercontinuum light sources and a costume-made spectrometer with 400 nm bandwidth were combined with a high NA microscope objective in a setup for tissue and small animal imaging. Using this setup and computation corrections, volumetric imaging at 1.5 μm resolution is possible. Cellular and near cellular resolution is demonstrated in porcine cornea and the drosophila larva, when computational correction of dispersion and aberrations is used. Due to the excellent correction of the used microscope objective, defocus was the main contribution to the aberrations. In addition, higher aberrations caused by the sample itself were successfully corrected. Dispersion and aberrations are closely related artifacts in microscopic OCT imaging. Hence they can be corrected in the same way by optimization of the image quality. This way microscopic resolution is easily achieved in OCT imaging of static biological tissues.}, keywords = {OCM}, pubstate = {published}, tppubtype = {inproceedings} } |
Hinnerk
Schulz-Hildebrandt,
Mario
Pieper,
Martin
Ahrens,
Christian
Idel,
Barbara
Wollenberg,
Peter
König, and
Gereon
Hüttmann,
Novel endoscope with increased depth of field for imaging human nasal tissue by microscopic optical coherence tomography, Biomedical Optics Express , pp. 636-647, 2018.
Novel endoscope with increased depth of field for imaging human nasal tissue by microscopic optical coherence tomography, Biomedical Optics Express , pp. 636-647, 2018.
DOI: | 10.1364/BOE.9.000636 |
File: | abstract.cfm |
Bibtex: | ![]() @article{schulz2018novel, title = {Novel endoscope with increased depth of field for imaging human nasal tissue by microscopic optical coherence tomography}, author = {Schulz-Hildebrandt, H; Pieper, M; Stehmar,C; Ahrens, M; Idel, C; Wollenberg,B; K\"{o}nig,P and Gereon H\"{u}ttmann}, editor = {Optic Socie Amer}, url = {https://www.osapublishing.org/abstract.cfm?URI=boe-9-2-636 https://www.osapublishing.org/boe/viewmedia.cfm?uri=boe-9-2-636&seq=0}, doi = {10.1364/BOE.9.000636}, isbn = {10.1364/BOE.9.000636}, year = {2018}, date = {2018-01-16}, journal = {Biomedical Optics Express}, pages = {636-647}, abstract = {Intravital microscopy (IVM) offers the opportunity to visualize static and dynamic changes of tissue on a cellular level. It is a valuable tool in research and may considerably improve clinical diagnosis. In contrast to confocal and non-linear microscopy, optical coherence tomography (OCT) with microscopic resolution (mOCT) provides intrinsically cross-sectional imaging. Changing focus position is not needed, which simplifies especially endoscopic imaging. For in-vivo imaging, here we are presenting endo-microscopic OCT (emOCT). A graded-index-lens (GRIN) based 2.75 mm outer diameter rigid endoscope is providing 1.5 \textendash 2 μm nearly isotropic resolution over an extended field of depth. Spherical and chromatic aberrations are used to elongate the focus length. Simulation of the OCT image formation, suggests overall a better image quality in this range compared to a focused Gaussian beam. Total imaging depth at a reduced sensitivity and lateral resolution is more than 200 μm. Using a frame rate of 80 Hz cross-sectional images of concha nasalis were demonstrated in humans, which could resolve cilial motion, cellular structures of the epithelium, vessels and blood cells. Mucus transport velocity was determined successfully. The endoscope may be used for diagnosis and treatment control of different lung diseases like cystic fibrosis or primary ciliary dyskinesia, which manifest already at the nasal mucosa.}, keywords = {Endoskope, OCM}, pubstate = {published}, tppubtype = {article} } |
J
Rudnitzki, and
G
Huettmann,
siRNA release from gold nanoparticles by nanosecond pulsed laser irradiation and analysis of the involved temperature increase, Journal of BIOPHOTONICS , 2018.
siRNA release from gold nanoparticles by nanosecond pulsed laser irradiation and analysis of the involved temperature increase, Journal of BIOPHOTONICS , 2018.
DOI: | 10.1002/jbio.201700329 |
Bibtex: | ![]() @article{Rahmanzadeh2018, author = {Rudnitzki, F; Feineis, S; Rahmanzadeh, R; Endl, E; Lutz, J; Groll, J and Huettmann, G}, title = {siRNA release from gold nanoparticles by nanosecond pulsed laser irradiation and analysis of the involved temperature increase}, journal = {Journal of BIOPHOTONICS}, doi = {10.1002/jbio.201700329}, keywords = {cavitation|cell manipulation|controlled release|gold nanoparticle bio-conjugates|laser nanoeffects}, abstract = {Nanosecond pulsed laser irradiation can trigger a release of nucleic acids from gold nanoparticles, but the involved nanoeffects are not fully understood yet. Here we investigate the release of coumarin labeled siRNA from 15 to 30 nm gold particles after nanosecond pulsed laser irradiation. Temperatures in the particle and near the surface were calculated for the different radiant exposures. Upon irradiation with laser pulses of 4 nanosecond duration release started for both particle sizes at a calculated temperature increase of approximately 500 K. Maximum coumarin release was observed for 15 nm particles after irradiation with radiant exposure of 80 mJ cm−2 and with 32 mJ cm−2 for 30 nm particles. This corresponds to a temperature increase of 815 and 900 K, respectively. Our results show that the molecular release by nanosecond pulsed irradiation is based on a different mechanism compared to continuous or femtosecond irradiation. Local temperatures are considerably higher and it is expected that bubble formation plays a crucial role in release and damage to cellular structures. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim}, year = {2018}, type = {Journal Article} } |
2017
Sarah
Kretschmer,
Mario
Pieper,
Antje
Klinger,
Gereon
Hüttmann, and
Peter
König,
Imaging of Wound Closure of Small Epithelial Lesions in the Mouse Trachea, Am J Pathol , vol. 187, no. 11, pp. 2451-2460, Nov. 2017.
Imaging of Wound Closure of Small Epithelial Lesions in the Mouse Trachea, Am J Pathol , vol. 187, no. 11, pp. 2451-2460, Nov. 2017.
DOI: | 10.1016/j.ajpath.2017.07.006 |
Bibtex: | ![]() @article{Kretschmer2017, author = {Kretschmer, S; Pieper, M; Klinger, A; Hüttmann, G. and König, P.}, title = {Imaging of Wound Closure of Small Epithelial Lesions in the Mouse Trachea}, journal = {Am J Pathol}, ISSN = {0002-9440}, DOI = {10.1016/j.ajpath.2017.07.006}, year = {2017}, pages = {2451-2460}, type = {Journal Article} } |
Dierck
Hillmann,
Hendrik
Spahr,
Carola
Hain,
Laura
Hinkel,
Gesa
Franke, and
Gereon
Hüttmann,
Off-axis reference beam for full-field swept-source OCT and holoscopy, Opt Expr , vol. 25, no. 22, pp. 27770-27784, Oct. 2017.
Off-axis reference beam for full-field swept-source OCT and holoscopy, Opt Expr , vol. 25, no. 22, pp. 27770-27784, Oct. 2017.
DOI: | 10.1364/OE.25.027770 |
Bibtex: | ![]() @article{Hillmann2017, author = {Hillmann, D; Spahr, H; Sudkamp, H; Hain, C; Hinkel, L; Franke, G and Hüttmann, G}, title = {Off-axis reference beam for full-field swept-source OCT and holoscopy}, journal = {Opt Expr}, pages = {27770-27784}, DOI = {10.1364/OE.25.027770}, year = {2017}, type = {Journal Article} } |
Clara
Pfäffle,
Hendrik
Spahr,
Dierck
Hillmann,
Helge
Sudkamp,
Gesa
Franke,
Peter
Koch, and
Gereon
Hüttmann,
Reduction of frame rate in full-field swept-source optical coherence tomography by numerical motion correction [Invited], Biomedical Optics Express , vol. 8, no. 3, pp. 1499-1511, Mar. 2017.
Reduction of frame rate in full-field swept-source optical coherence tomography by numerical motion correction [Invited], Biomedical Optics Express , vol. 8, no. 3, pp. 1499-1511, Mar. 2017.
DOI: | 10.1364/BOE.8.001499 |
Weblink: | https://doi.org/10.1364/BOE.8.001499 |
File: | abstract.cfm |
Bibtex: | ![]() @article{Pfäffle2017, author = {Pfäffle, Clara and Spahr, Hendrik and Hillmann, Dierck and Sudkamp, Helge and Franke, Gesa and Koch, Peter and Hüttmann, Gereon}, title = {Reduction of frame rate in full-field swept-source optical coherence tomography by numerical motion correction [Invited]}, journal = {Biomedical Optics Express}, volume = {8}, number = {3}, pages = {1499-1511}, keywords = {Image reconstruction-restoration Optical coherence tomography}, url = {http://www.osapublishing.org/boe/abstract.cfm?URI=boe-8-3-1499}, year = {2017}, type = {Journal Article} } |