x-x
Liang,
N.
Linz,
S.
Freidank,
G.
Paltauf, and
A
Vogel,
Comprehensive analysis of spherical bubble oscillations and shock wave emission in laser-induced cavitation, Journal of Fluid Mechanics , vol. 940, pp. A5, 2022.
Comprehensive analysis of spherical bubble oscillations and shock wave emission in laser-induced cavitation, Journal of Fluid Mechanics , vol. 940, pp. A5, 2022.
DOI: | 10.1017/jfm.2022.202 |
Bibtex: | ![]() @article{Liang2022, author = {Liang, X-X;Linz, N;Freidank, S;Paltauf, G and Vogel, A}, title = {Comprehensive analysis of spherical bubble oscillations and shock wave emission in laser-induced cavitation}, keywords = {bubble dynamics, cavitation, shock waves}, journal = {Journal of Fluid Mechanics}, volume = {940}, pages = {A5}, ISSN = {0022-1120}, DOI = {10.1017/jfm.2022.202}, year = {2022}, type = {Journal Article} } |
X-X
Liang, and
A
Vogel,
Probing neuronal functions with precise and targeted laser ablation in the living cortex: comment, Optica , vol. 9(8), pp. 868-871, 2022.
Probing neuronal functions with precise and targeted laser ablation in the living cortex: comment, Optica , vol. 9(8), pp. 868-871, 2022.
DOI: | 10.1364/OPTICA.454469 |
Bibtex: | ![]() @article{Liang2022, author = {Liang, X-X and Vogel, A}, title = {Probing neuronal functions with precise and targeted laser ablation in the living cortex: comment}, journal = {Optica}, volume = {9(8)}, keywords = {Attenuation coefficient, Femtosecond lasers, Laser ablation, Laser irradiation, Numerical simulation, Thermal effects}, pages = {868-871}, DOI = {10.1364/OPTICA.454469}, year = {2022}, type = {Journal Article} } |
Tobias
Fischer,
Antje
Klinger,
Dorthe
Smolinski,
Regina
Orzekowsky-Schröder,
Falk
Nitzsche,
Alfred
Vogel,
Gereon
Hüttmann, and
Andreas
Gebert,
High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , pp. 1-8, 2020.
High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , pp. 1-8, 2020.
File: | s00441-020-03167-z |
Bibtex: | ![]() @article{Fischer2020, author = {Fischer, T;Klinger, A;von Smolinski, D;Orzekowsky-Schroeder, R;Nitzsche, F;Bölke, T;Vogel, A;Hüttmann, G and Gebert, A}, title = {High-resolution imaging of living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures}, journal = {Cell and Tissue Research}, pages = {1-8}, ISSN = {1432-0878}, url = {https://doi.org/10.1007/s00441-020-03167-z}, year = {2020}, type = {Journal Article} } |
Tobias
Fischer,
Antje
Klinger,
Dorthe
Smolinski,
Regina
Orzekowsky-Schroeder,
Falk
Nitzsche,
Alfred
Vogel,
Gereon
Hüttmann, and
Andreas
Gebert,
High-resolution imaging of the living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , 2019.
High-resolution imaging of the living gut mucosa: lymphocyte clusters beneath intestinal M cells are highly dynamic structures, Cell and Tissue Research , 2019.
Z
Liang, and
A
Vogel,
Multi-rate-equation modeling of the energy spectrum of laser-induced conduction band electrons in water, Opt Expr , pp. 4672-4693, 2019.
Multi-rate-equation modeling of the energy spectrum of laser-induced conduction band electrons in water, Opt Expr , pp. 4672-4693, 2019.
DOI: | 10.1364/OE.27.004672 |
Bibtex: | ![]() @article{Liang2019, author = {Liang, X-X; Zhang, Z and Vogel, A}, title = {Multi-rate-equation modeling of the energy spectrum of laser-induced conduction band electrons in water}, journal = {Opt Expr}, pages = {4672-4693}, DOI = {10.1364/OE.27.004672}, year = {2019}, type = {Journal Article} } |
R
Uzunbajakava, and
A
Vogel,
Highlighting the nuances behind interaction of picosecond pulses with human skin: Relating distinct laser-tissue interactions to their potential in cutaneous interventions, in Progress in Biomedical Optics and Imaging - Proceedings of SPIE , 2018.
Highlighting the nuances behind interaction of picosecond pulses with human skin: Relating distinct laser-tissue interactions to their potential in cutaneous interventions, in Progress in Biomedical Optics and Imaging - Proceedings of SPIE , 2018.
DOI: | 10.1117/12.2307804 |
Bibtex: | ![]() @inproceedings{Vogel2018, author = {Uzunbajakava, N E; Varghese, B; Botchkareva, N V; Verhagen, R and Vogel, A}, title = {Highlighting the nuances behind interaction of picosecond pulses with human skin: Relating distinct laser-tissue interactions to their potential in cutaneous interventions}, booktitle = {Progress in Biomedical Optics and Imaging - Proceedings of SPIE}, volume = {10492} , DOI = {10.1117/12.2307804}, year = {2018}, date = {2018-20-02}, type = {Conference Proceedings}, year = { 2018} } |
Sijia
Wang,
Gereon
Hüttmann,
Thomas
Scholzen,
Zhenxi
Zhang,
Alfred
Vogel,
Tayyaba
Hasan, and
Ramtin
Rahmanzadeh,
A light-controlled switch after dual targeting of proliferating tumor cells via the membrane receptor EGFR and the nuclear protein Ki-67, Sci Rep , vol. 6, pp. 27032, 2016.
A light-controlled switch after dual targeting of proliferating tumor cells via the membrane receptor EGFR and the nuclear protein Ki-67, Sci Rep , vol. 6, pp. 27032, 2016.
DOI: | 10.1038/srep27032 |
Bibtex: | ![]() @article{Wang2016, author = {Wang, S. and Huttmann, G. and Scholzen, T. and Zhang, Z. and Vogel, A. and Hasan, T. and Rahmanzadeh, R.}, title = {A light-controlled switch after dual targeting of proliferating tumor cells via the membrane receptor EGFR and the nuclear protein Ki-67}, journal = {Sci Rep}, volume = {6}, pages = {27032}, note = {2045-2322 Wang, Sijia Huttmann, Gereon Scholzen, Thomas Zhang, Zhenxi Vogel, Alfred Hasan, Tayyaba Rahmanzadeh, Ramtin Journal Article England Sci Rep. 2016 Jun 1;6:27032. doi: 10.1038/srep27032.}, abstract = {Using nanotechnology for optical manipulation of molecular processes in cells with high spatial and temporal precision promises new therapeutic options. Especially tumor therapy may profit as it requires a combination of both selectivity and an effective cell killing mechanism. Here we show a dual targeting approach for selective and efficient light-controlled killing of cells which are positive for epidermal growth factor receptor (EGFR) and Ki-67. Liposomes with the covalently linked EGFR antibody Erbitux enabled selective uptake of FITC-labeled Ki-67 antibody TuBB-9 in EGFR-positive cells pre-loaded with the photoactive dye BPD. After irradiation at 690 nm, BPD disrupted the endosomal membranes and delivered the antibodies to the nucleoli of the cells. The second irradiation at 490 nm activated the FITC-labeled TuBB-9, which caused inactivation of the Ki-67 protein and subsequent cell death via apoptosis. Efficient cell killing was possible at nanomolar concentrations of TuBB-9 due to the effective transport by immune liposomes and the high efficacy of the Ki-67 light-inactivation. Delivery of the liposomal constructs and cell destruction correlated well with the EGFR expression pattern of different cell lines (HeLa, OVCAR-5, MCF-7, and human fibroblasts), demonstrating an excellent selectivity.}, ISSN = {2045-2322}, DOI = {10.1038/srep27032}, year = {2016}, type = {Journal Article} } |
A.
Klinger,
L.
Krapf,
R.
Orzekowsky-Schroeder,
N.
Koop, and
Alfred
Vogel,
Intravital autofluorescence 2-photon microscopy of murine intestinal mucosa with ultra-broadband femtosecond laser pulse excitation: image quality, photodamage, and inflammation, J Biomed Opt , vol. 20, no. 11, pp. 116001, 2015.
Intravital autofluorescence 2-photon microscopy of murine intestinal mucosa with ultra-broadband femtosecond laser pulse excitation: image quality, photodamage, and inflammation, J Biomed Opt , vol. 20, no. 11, pp. 116001, 2015.
DOI: | 10.1117/1.jbo.20.11.116001 |
Bibtex: | ![]() @article{Klinger2017, author = {Klinger, A. and Krapf, L. and Orzekowsky-Schroeder, R. and Koop, N. and Vogel, A. and Huttmann, G.}, title = {Intravital autofluorescence 2-photon microscopy of murine intestinal mucosa with ultra-broadband femtosecond laser pulse excitation: image quality, photodamage, and inflammation}, journal = {J Biomed Opt}, volume = {20}, number = {11}, pages = {116001}, ISSN = {1083-3668}, DOI = {10.1117/1.jbo.20.11.116001}, year = {2015}, type = {Journal Article} } |
Sijia
Wang,
Zhenxi
Zhang,
Alfred
Vogel,
Reginald
Birngruber,
Shifalika
Tangutoori,
Tayyaba
Hasan, and
Ramtin
Rahmanzadeh,
Light-Controlled Delivery of Monoclonal Antibodies for Targeted Photoinactivation of Ki-67, Mol Pharm , vol. 12, no. 9, pp. 3272-81, 2015.
Light-Controlled Delivery of Monoclonal Antibodies for Targeted Photoinactivation of Ki-67, Mol Pharm , vol. 12, no. 9, pp. 3272-81, 2015.
DOI: | 10.1021/acs.molpharmaceut.5b00260 |
Bibtex: | ![]() @article{Wang2015, author = {Wang, S. and Huttmann, G. and Zhang, Z. and Vogel, A. and Birngruber, R. and Tangutoori, S. and Hasan, T. and Rahmanzadeh, R.}, title = {Light-Controlled Delivery of Monoclonal Antibodies for Targeted Photoinactivation of Ki-67}, journal = {Mol Pharm}, note = {1543-8392 Wang, Sijia Huttmann, Gereon Zhang, Zhenxi Vogel, Alfred Birngruber, Reginald Tangutoori, Shifalika Hasan, Tayyaba Rahmanzadeh, Ramtin Journal article Mol Pharm. 2015 Aug 13.}, abstract = {The selective inhibition of intracellular and nuclear molecules such as Ki-67 holds great promise for the treatment of cancer and other diseases. However, the choice of the target protein and the intracellular delivery of the functional agent remain crucial challenges. Main hurdles are (a) an effective delivery into cells, (b) endosomal escape of the delivered agents, and (c) an effective, externally triggered destruction of cells. Here we show a light-controlled two-step approach for selective cellular delivery and cell elimination of proliferating cells. Three different cell-penetrating nano constructs, including liposomes, conjugates with the nuclear localization sequence (NLS), and conjugates with the cell penetrating peptide Pep-1, delivered the light activatable antibody conjugate TuBB-9-FITC, which targets the proliferation associated protein Ki-67. HeLa cells were treated with the photosensitizer benzoporphyrin monoacid derivative (BPD) and the antibody constructs. In the first optically controlled step, activation of BPD at 690 nm triggered a controlled endosomal escape of the TuBB-9-FITC constructs. In more than 75% of Ki-67 positive, irradiated cells TuBB-9-FITC antibodies relocated within 24 h from cytoplasmic organelles to the cell nucleus and bound to Ki-67. After a second light irradiation at 490 nm, which activated FITC, cell viability decreased to approximately 13%. Our study shows an effective targeting strategy, which uses light-controlled endosomal escape and the light inactivation of Ki-67 for cell elimination. The fact that liposomal or peptide-assisted delivery give similar results leads to the additional conclusion that an effective mechanism for endosomal escape leaves greater variability for the choice of the delivery agent.}, keywords = {endosomal entrapment liposome nanotechnology nuclear localization sequence (NLS) photodynamic therapy}, ISSN = {1543-8384}, DOI = {10.1021/acs.molpharmaceut.5b00260}, year = {2015}, type = {Journal Article} } |
A
Vogel,
S
Freidank, and
N.
Linz,
Alternativen zur Femtosekundentechnologie: UV Subnanosekunden-pulse und Ringfoki für LASIK Flaperzeugung (at press), Ophthalomologe , vol. 111, no. 6, 2014.
Alternativen zur Femtosekundentechnologie: UV Subnanosekunden-pulse und Ringfoki für LASIK Flaperzeugung (at press), Ophthalomologe , vol. 111, no. 6, 2014.
Alfred
Vogel,
N.
Linz,
S.
Freidank, and
G.
Paltauf,
Femtosecond-laser-induced nanocavitation in water: implications for optical breakdown threshold and cell surgery, vol. 100, no. 3, pp. 23, 2008.
Femtosecond-laser-induced nanocavitation in water: implications for optical breakdown threshold and cell surgery, vol. 100, no. 3, pp. 23, 2008.
V.
Horneffer,
N.
Linz, and
Alfred
Vogel,
Principles of laser-induced separation and transport of living cells, J Biomed Opt , vol. 12, no. 5, pp. 054016, 2007.
Principles of laser-induced separation and transport of living cells, J Biomed Opt , vol. 12, no. 5, pp. 054016, 2007.
A
Vogel,
V.
Horneffer,
B.
Lorenz,
N.
Linz,
S.
Freidank, and
A.
Gebert,
Principles of laser microdissection and catapulting of histologic specimens and live cells, in Laser Manipulation of Cells and Tissues, Methods in Cell Biology , Berns, M. and Greulich, K.O., Eds. San Diego: Academic Press Elsevier, 2007, pp. 153-205.
Principles of laser microdissection and catapulting of histologic specimens and live cells, in Laser Manipulation of Cells and Tissues, Methods in Cell Biology , Berns, M. and Greulich, K.O., Eds. San Diego: Academic Press Elsevier, 2007, pp. 153-205.
A
Vogel,
J.
Noack, and
G.
Paltauf,
Mechanisms of femtosecond laser nanoprocessing of biological cells and tissues, in The Eigth International Conference on Laser Ablation (COLA 2005) , Herman, P. and Hess, W ., Eds. 2007, pp. 249-254.
Mechanisms of femtosecond laser nanoprocessing of biological cells and tissues, in The Eigth International Conference on Laser Ablation (COLA 2005) , Herman, P. and Hess, W ., Eds. 2007, pp. 249-254.
Alfred
Vogel,
J.
Noack,
N.
Linz,
S.
Freidank, and
G.
Paltauf,
Chapter 18 Femtosecond laser nanosurgery of biological cells and tissues, in Handai Nanophotonics , Hiroshi Masuhara, Satoshi Kawata and Fumio, Tokunaga, Eds. Elsevier, 2007, pp. 273-286.
Chapter 18 Femtosecond laser nanosurgery of biological cells and tissues, in Handai Nanophotonics , Hiroshi Masuhara, Satoshi Kawata and Fumio, Tokunaga, Eds. Elsevier, 2007, pp. 273-286.
Alfred
Vogel,
K.
Lorenz,
V.
Horneffer,
Dorthe
Smolinski, and
A.
Gebert,
Mechanisms of laser-induced dissection and transport of histologic specimens., Biophys J , vol. 93, pp. 4481-4500, 2007.
Mechanisms of laser-induced dissection and transport of histologic specimens., Biophys J , vol. 93, pp. 4481-4500, 2007.
File: | biophysj.106.102277 |
Bibtex: | ![]() @article{Vogel2007-7, author = {Vogel, A. and Lorenz, K. and Horneffer, V. and Hüttmann, G. and von Smolinski, D. and Gebert, A.}, title = {Mechanisms of laser-induced dissection and transport of histologic specimens.}, journal = {Biophys J}, volume = {93}, pages = {4481-4500}, year = { 2007}, url = { https://doi.org/10.1529/biophysj.106.102277} } |
Alfred
Vogel,
J
Noack, and
G.
Paltauf,
Femtosecond plasma-mediated nanosurgery of cells and tissues., in Laser Ablation , ), Phipps C (Hrsg., Eds. Springer, Heidelberg, 2006, pp. 217-262.
Femtosecond plasma-mediated nanosurgery of cells and tissues., in Laser Ablation , ), Phipps C (Hrsg., Eds. Springer, Heidelberg, 2006, pp. 217-262.
Alfred
Vogel,
I.
Apitz,
S.
Freidank, and
R.
Dijkink,
Sensitive high-resolution white-light Schlieren technique with a large dynamic range for the investigation of ablation dynamics, Opt. Lett. , vol. 31, pp. 1812-1814, 2006.
Sensitive high-resolution white-light Schlieren technique with a large dynamic range for the investigation of ablation dynamics, Opt. Lett. , vol. 31, pp. 1812-1814, 2006.
File: | OL.31.001812 |
Bibtex: | ![]() @article{Vogel2006-1, author = {Vogel, A. and Apitz, I. and Freidank, S. and Dijkink, R.}, title = {Sensitive high-resolution white-light Schlieren technique with a large dynamic range for the investigation of ablation dynamics}, journal = {Opt. Lett.}, volume = {31}, pages = {1812-1814}, year = { 2006}, url = { https://doi.org/10.1364/OL.31.001812} } |
Alfred
Vogel,
J.
Noack,
N.
Linz,
S.
Freidank, and
G.
Paltauf,
Femtosecond laser nanosurgery of biological cells and tissues, in 4th International Congress on Laser Advanced Materials Processing , 2006.
Femtosecond laser nanosurgery of biological cells and tissues, in 4th International Congress on Laser Advanced Materials Processing , 2006.
File: | download |
Bibtex: | ![]() @inproceedings{Vogel-2006, author = {Vogel, A. and Noack, J. and Hüttmann, G. and Linz, N. and Freidank, S. and Paltauf, G.}, title = {Femtosecond laser nanosurgery of biological cells and tissues}, booktitle = {4th International Congress on Laser Advanced Materials Processing}, Year = { 2006}, URL = { http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.713.4169&rep=rep1&type=pdf} } |
H.
Hoerauf,
A.
Brix,
J.
Winkler,
G.
Droege,
H.
Laqua, and
Alfred
Vogel,
Photoablation of inner limiting membrane and inner retinal layers using the erbium : YAG-laser: An in vitro study, Lasers in Surgery and Medicine , vol. 38, no. 1, pp. 52-61, 2006.
Photoablation of inner limiting membrane and inner retinal layers using the erbium : YAG-laser: An in vitro study, Lasers in Surgery and Medicine , vol. 38, no. 1, pp. 52-61, 2006.
DOI: | Doi 10.1002/Lsm.20269 |
File: | WOS:000235149600007 |
Bibtex: | ![]() @article{Hoerauf2006, author = {Hoerauf, H. and Brix, A. and Winkler, J. and Droege, G. and Winter, C. and Birngruber, R. and Laqua, H. and Vogel, A.}, title = {Photoablation of inner limiting membrane and inner retinal layers using the erbium : YAG-laser: An in vitro study}, journal = {Lasers in Surgery and Medicine}, volume = {38}, number = {1}, pages = {52-61}, note = {009YN Times Cited:4 Cited References Count:51}, abstract = {Background and Objectives: To explore the potential of Er:YAG-laser irradiation for precise and tractionless retinal tissue and inner limiting membrane ablation. Materials and Methods: We used free-running Er:YAG-laser irradiation (lambda = 2.94 mu m) transmitted either through a 10 em long low-OH-quartz fiber or a 2 m long sapphire fiber that produced a more homogenous light distribution at the fiber tip. Retinal ablation in porcine retinal explants was performed under air or perfluorodecaline (PFD). Ablation depth was evaluated by optical coherence tomography (OCT) and from histologic sections. Results: A radiant exposure of 5.0 J/cm(2) delivered through a low-OH-quartz fiber and PFD caused a complete transsection of the neurosensory retina. Radiant exposures between 3.5 and 2.0 J/cm(2) resulted in marked variations of ablation depth and adjacent thermal damage. By contrast, laser pulses of 4.0 and 3.0 J/cm(2) transmitted through the sapphire fiber produced more homogenous defect patterns and less thermal damage. Close to the ablation threshold, with 1.0-2.0 J/cm(2), ablation was limited to a 10-20 mu m thin layer of the neural retina. Conclusions: We achieved in vitro ablation of inner retinal layers, but could not produce selective and reproducible ILM removal.}, keywords = {macular surgery optical coherence tomography perfluorocarbon liquid retina retinal explant optical coherence tomography macular hole surgery experimental vitreous membranes er-yag vitreoretinal surgery clinical-experience indocyanine green excimer-laser pig eyes ablation}, ISSN = {0196-8092}, DOI = {Doi 10.1002/Lsm.20269}, url = {<Go to ISI>://WOS:000235149600007}, year = {2006}, type = {Journal Article} } |
A . Vogel,
Stress wave emission and cavitation bubble dynamics by nanosecond optical breakdown in a tissue phantom., J Fluid Mech , vol. 558, pp. 281-308, 2006.
Stress wave emission and cavitation bubble dynamics by nanosecond optical breakdown in a tissue phantom., J Fluid Mech , vol. 558, pp. 281-308, 2006.
V.
Horneffer,
Alfred
Vogel,
B.
Sägmüller, and
K.
Schütze,
Microdissection, catapulting, and microinjection of biologic specimens with femtosecond laser pulses, in SPIE/OSA Conference on Biomedical Optics ECBO,12.-16.06.2005 , 2005.
Microdissection, catapulting, and microinjection of biologic specimens with femtosecond laser pulses, in SPIE/OSA Conference on Biomedical Optics ECBO,12.-16.06.2005 , 2005.
File: | abstract.cfm |
Bibtex: | ![]() @inproceedings{Horneffer, author = {Horneffer, V. and Vogel, A. and Sägmüller, B. and Schütze, K.}, title = {Microdissection, catapulting, and microinjection of biologic specimens with femtosecond laser pulses}, booktitle = {SPIE/OSA Conference on Biomedical Optics ECBO,12.-16.06.2005}, } |
Alfred
Vogel,
J.
Noack, and
G.
Paltauf,
Mechanisms of femtosecond laser nanosurgery of biological cells and tissues, Appl. Phys B , vol. 81, pp. 1015-1047, 2005.
Mechanisms of femtosecond laser nanosurgery of biological cells and tissues, Appl. Phys B , vol. 81, pp. 1015-1047, 2005.
I.
Apitz, and
Alfred
Vogel,
Material ejection in nanosecond Er:YAG laser ablation of water, liver, and skin, Applied Physics A: Materials Science & Processing , vol. 81, no. 2, pp. 329-338, 2005.
Material ejection in nanosecond Er:YAG laser ablation of water, liver, and skin, Applied Physics A: Materials Science & Processing , vol. 81, no. 2, pp. 329-338, 2005.