Wolfgang Draxinger

Doktorand


BMO, AG-Huber
Universität zu Lübeck
Maria-Goeppert-Str. 1
23562 Lübeck

Gebäude MFC1, Raum 2

Email:
Phone:
+49 (0)451 3101 3231/3235(lab)
Fax:
+49 (0)451 3101 3233


Publikationen

2018

  • Pfeiffer, Tom / Petermann, Markus /Draxinger, Wolfgang / Jirauschek, Christian and Huber, Robert: Ultra low noise Fourier domain mode locked laser for high quality magahertz optical coherence tomography. Biomedical Optics Express, no. 9, pp. 4130-4148, 2018
    BibTeX Link Link
    @article{Pfeiffer2018,
       author = {Pfeiffer, Tom / Petermann, Markus /Draxinger, Wolfgang / Jirauschek, Christian and Huber, Robert},
       title = {Ultra low noise Fourier domain mode locked laser for high quality magahertz optical coherence tomography},
       journal = {Biomedical Optics Express},
       volume = {9},
       number = {9},
       pages = {4130-4148},
        DOI = {10.1364/BOE.9.004130},
    url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052736688&doi=10.1364%2fBOE.9.004130&partnerID=40&md5=1ed100666a2d806f51b68e70ba13808c}
       year = {2018},
       type = {Journal Article}
    }
    
  • Hinnerk Schulz-Hildebrandt /Tom Pfeiffer /Tim Eixmann /Sabrina Lohmann /Martin Ahrens /Josua Rehra /Wolfgang Draxinger /Peter König /Robert Huber and Gereon Hüttmann: High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography. Optics Letters, no. 43, pp. 4386-4389, 2018
    BibTeX Link Link
    @article{Schulz-Hildebrandt2018b,
    title = {High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography},
    author = {Hinnerk Schulz-Hildebrandt /Tom Pfeiffer /Tim Eixmann /Sabrina Lohmann /Martin Ahrens /Josua Rehra /Wolfgang Draxinger /Peter K\"{o}nig /Robert Huber and Gereon H\"{u}ttmann},
    url = {ttp://ol.osa.org/abstract.cfm?URI=ol-43-18-4386},
     DOI = {10.1364/OL.43.004386},
    
    year = {2018},
    date = {2018-09-05},
    journal = {Optics Letters},
    volume = {43},
    number = {18},
    pages = {4386-4389},
    abstract = {We present a forward-viewing fiber scanning endoscope (FSE) for high-speed volumetric optical coherence tomography (OCT). The reduction in size of the probe was achieved by substituting the focusing optics by an all-fiber-based imaging system which consists of a combination of scanning single-mode fibers, a glass spacer, made from a step-index multi-mode fiber, and a gradient-index fiber. A lateral resolution of 11 μm was achieved at a working distance of 1.2 mm. The newly designed piezo-based FSE has an outer diameter of 1.6 mm and a rigid length of 13.5 mm. By moving the whole imaging optic in spirals for scanning the sample, the beam quality remains constant over the entire field of view with a diameter of 0.8 mm. The scanning frequency was adjusted to 1.22 kHz for use with a 3.28 MHz Fourier domain mode locked OCT system. Densely sampled volumes have been imaged at a rate of 6 volumes per second.
    
    © 2018 Optical Society of America},
    keywords = {Endoskope},
    pubstate = {published},
    tppubtype = {article}
    }

2017

  • Wang, Tianshi and Pfeiffer, Tom and Wu, Min and Wieser, Wolfgang and Amenta, Gaetano and Draxinger, Wolfgang and van der Steen, Antonius F. W. and Huber, Robert and Soest, Gijs van: Thermo-elastic optical coherence tomography. Optics Letters, no. 42, pp. 3466-3469, 2017
    BibTeX Link
    @article{HU_Wang2017,
       author = {Wang, Tianshi and Pfeiffer, Tom and Wu, Min and Wieser, Wolfgang and Amenta, Gaetano and Draxinger, Wolfgang and van der Steen, Antonius F. W. and Huber, Robert and Soest, Gijs van},
       title = {Thermo-elastic optical coherence tomography},
       journal = {Optics Letters},
       volume = {42},
       number = {17},
       pages = {3466-3469},
       DOI = {10.1364/OL.42.003466},
       year = {2017},
       type = {Journal Article}
    }
    
  • Wang, Tianshi and Pfeiffer, Tom and Wu, Min and Wieser, Wolfgang and Draxinger, Wolfgang and van der Steen, Antonius F. W. and Huber, Robert and van Soest, Gijs: Short pulse laser induced thermo-elastic deformation imaging. in Proc. SPIE, no. 10062, pp. 100620C-100620C-4, 2017
    BibTeX Link
    @inproceedings{Wang2017,
       author = {Wang, Tianshi and Pfeiffer, Tom and Wu, Min and Wieser, Wolfgang and Draxinger, Wolfgang and van der Steen, Antonius F. W. and Huber, Robert and van Soest, Gijs},
       title = {Short pulse laser induced thermo-elastic deformation imaging},
    booktitle = Proc. SPIE},
      volume = {10062},
      year = {2017},
       pages = {100620C-100620C-4},
      url = {http://dx.doi.org/10.1117/12.2251502},
       type = {Conference Proceedings}
    }
    
    
  • Pfeiffer, Tom and Draxinger, Wolfgang and Grill, C and Huber, R: Long-range live 3D-OCT at different spectral zoom levels. in Proc. SPIE, no. 10416, pp. 104160L1-4, 2017
    BibTeX
    @inproceedings{HU_Pfeiffer2017,
       author = {Pfeiffer, Tom and Draxinger, Wolfgang and Grill, C and Huber, R},
       title = {Long-range live 3D-OCT at different spectral zoom levels},
       booktitle = {Proc. SPIE},
       volume = {10416},
       pages = {104160L1-4},
       year = {2017},
       type = {Conference Proceedings}
    }
    
  • Pfeiffer, Tom and Draxinger, Wolfgang and Wieser, Wolfgang and Klein, Thomas and Petermann, Markus and Huber, Robert: Analysis of FDML lasers with meter range coherence. in Proc. SPIE, no. 10053, pp. 100531T-100531T-6, 2017
    BibTeX Link
    @inproceedings{Pfeiffer2017,
       author = {Pfeiffer, Tom and Draxinger, Wolfgang and Wieser, Wolfgang and Klein, Thomas and Petermann, Markus and Huber, Robert},
       title = {Analysis of FDML lasers with meter range coherence},
       booktitle = {Proc. SPIE},
       volume = {10053},
       pages = {100531T-100531T-6},
        url = {http://dx.doi.org/10.1117/12.2254792},
    
      year = {2017},
       type = {Conference Proceedings}
    }
    

2015

  • Kolb, Jan Philip and Klein, Thomas and Wieser, Wolfgang and Draxinger, Wolfgang and Huber, Robert: High definition in vivo retinal volumetric video rate OCT at 0.6 Giga-voxels per second. in Proc. SPIE, no. 9541, pp. 95410Z-95410Z-8, 2015
    BibTeX Link
    @inproceedings{HU_2015_Kolb_d,
    author = {Kolb, Jan Philip and Klein, Thomas and Wieser, Wolfgang and Draxinger, Wolfgang and Huber, Robert},
    title = {High definition in vivo retinal volumetric video rate OCT at 0.6 Giga-voxels per second },
    booktitle = {Proc. SPIE },
    type = {Conference Proceedings},
    volume = {9541},
    pages = {95410Z-95410Z-8},
    year = {2015},
    doi = {10.1117/12.2183768}
    }
  • Wieser, Wolfgang and Klein, Thomas and Draxinger, Wolfgang and Huber, Robert: Fully automated 1.5 MHz FDML laser with more than 100mW output power at 1310 nm. in Proc. SPIE, no. 9541, pp. 954116-954116-7, 2015
    BibTeX Link
    @inproceedings{HU_2015_Wieser_a,
    author = {Wieser, Wolfgang and Klein, Thomas and Draxinger, Wolfgang and Huber, Robert},
    title = { Fully automated 1.5 MHz FDML laser with more than 100mW output power at 1310 nm },
    booktitle = {Proc. SPIE },
    type = {Conference Proceedings},
    volume = {9541},
    pages = {954116-954116-7},
    year = {2015},
    doi = {10.1117/12.2183431}
    }
  • Kolb, Jan Philip and Klein, Thomas and Wieser, Wolfgang and Draxinger, Wolfgang and Huber, Robert: Full volumetric video rate OCT of the posterior eye with up to 195.2 volumes/s. in Proc. SPIE, no. 9312, pp. 931202-931202-7, 2015
    BibTeX Link
    @inproceedings{Kolb2015 ,
       author = {Kolb, Jan Philip and Klein, Thomas and Wieser, Wolfgang and Draxinger, Wolfgang and Huber, Robert },
       title = {Full volumetric video rate OCT of the posterior eye with up to 195.2 volumes/s},
       volume = {9312},
    Year={2015},
       pages = {931202-931202-7 },
       DOI = {10.1117/12.2077147 },
       booktitle = {Proc. SPIE },
       type = {Conference Proceedings}
    }
    
  • Mohler, Kathrin J. and Draxinger, Wolfgang and Klein, Thomas and Kolb, Jan Philip and Wieser, Wolfgang and Haritoglou, Christos and Kampik, Anselm and Fujimoto, James G. and Neubauer, Aljoscha S. and Huber, Robert and Wolf, Armin: Combined 60° Wide-Field Choroidal Thickness Maps and High-Definition En Face Vasculature Visualization Using Swept-Source Megahertz OCT at 1050 nm60° High-Definition MHz-OCT Imaging of the Choroid. Investigative Ophthalmology & Visual Science, no. 56, pp. 6284-6293, 2015
    BibTeX Link
    @article{HU_Mohler_2015,
    author = {Mohler, Kathrin J. and Draxinger, Wolfgang and Klein, Thomas and Kolb, Jan Philip and Wieser, Wolfgang and Haritoglou, Christos and Kampik, Anselm and Fujimoto, James G. and Neubauer, Aljoscha S. and Huber, Robert and Wolf, Armin},
    title = {Combined 60° Wide-Field Choroidal Thickness Maps and High-Definition En Face Vasculature Visualization Using Swept-Source Megahertz OCT at 1050 nm60° High-Definition MHz-OCT Imaging of the Choroid},
    journal = {Investigative Ophthalmology & Visual Science},
    volume = {56},
    number = {11},
    pages = {6284--6293},
    year = {2015},
    doi = {10.1167/iovs.15-16670},
    eprint = {/data/Journals/IOVS/934564/i1552-5783-56-11-6284.pdf}
    }

2014

  • Klein, Thomas and Draxinger, Wolfgang and Mohler, Kathrin and Kolb, Jan Philip and Wieser, Wolfgang and Kampik, Anselm and Neubauer, Aljoscha S. and Wolf, Armin and Huber, Robert: Wide-field choroidal thickness and en-face maps of patients created with MHz-OCT. Investigative Ophthalmology & Visual Science, no. 55, pp. 1620-1620, 2014
    BibTeX Link
    @article{Klein2014,
       author = {Klein, Thomas and Draxinger, Wolfgang and Mohler, Kathrin and Kolb, Jan Philip and Wieser, Wolfgang and Kampik, Anselm and Neubauer, Aljoscha S. and Wolf, Armin and Huber, Robert},
       title = {Wide-field choroidal thickness and en-face maps of patients created with MHz-OCT},
       journal = {Investigative Ophthalmology & Visual Science},
       volume = {55},
       number = {13},
       pages = {1620-1620},
       abstract = { PurposeTo study the feasibility of simultaneous peripheral and central choroidal thickness measurement and en-face visualization in patients with a variety of diseases, using a single high-resolution wide-field MHz-OCT dataset spanning more than 50 degrees field of view.  MethodsIn this retrospective study, choroidal morphology of 29 patients imaged with MHz-OCT was assessed. MHz-OCT is a custom SS-OCT operating at 1060nm and an axial line rate of 1.68MHz. The high speed, more than 30 times faster than current commercial devices, enabled a very high resolution scan protocol of 2088x1024 A-scans over a wide field of ~60 degrees. However, due to the very high speed, signal strength is lower compared to slower devices. Hence, thickness and structure maps were only created for selected datasets: The positions of Bruch’s membrane and choroid sclera junction were determined manually by a trained observer a subset of all A-scans, from which thickness and intensity maps were created.  ResultsDespite relative low signal strength, the choroid sclera junction could be clearly observed over the entire unshadowed image area in 15 of 29 patients. Apart from shadowing, visibility of this junction shows strong variation even within a single dataset due to varying retinal thickness, eye-blinks, saccades and retinal curvature. Thus, thickness could be evaluated at least in some areas for all 29 patients, especially in the periphery. Moreover, choroidal thickness varied considerably intra- and interindividually. In two patients, abrupt changes of the choroid were observed in the temporal periphery, which may resemble morphology or imaging artifact. In addition to thickness, en-face choroidal structure maps were extracted from the segmented OCT datasets. Visibility of choroidal vasculature in these maps correlates with choroidal thickness.  ConclusionsChoroidal thickness and structure in patients could be visualized over large areas for the first time. Due to focal choroidal thickness changes with large thickness gradients, high-density scan protocols may be favorable for OCT-based investigations of the choroid. En-face images of the choroid can be extracted from these high-resolution datasets, but the influence of choroidal thickness on the image information should be taken into account. Choroidal en-face image (top), color-coded thickness map with superimposed structural image (middle) and OCT B-frame (bottom) for two eyes (A,B).},
       ISSN = {1552-5783},
       url = {http://dx.doi.org/},
       year = {2014},
       type = {Journal Article}
    }
    
  • Wieser, Wolfgang and Draxinger, Wolfgang and Klein, Thomas and Karpf, Sebastian and Pfeiffer, Tom and Huber, Robert: High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s. Biomedical optics express, no. 5, pp. 2963-77, sep,, 2014
    BibTeX Link
    @Article{HU_2014_Wieser_a,
      Title                    = {{High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s}},
      Author                   = {Wieser, Wolfgang and Draxinger, Wolfgang and Klein, Thomas and Karpf, Sebastian and Pfeiffer, Tom and Huber, Robert},
      Journal                  = {Biomedical optics express},
      Year                     = {2014},
    
      Month                    = sep,
      Number                   = {9},
      Pages                    = {2963--77},
      Volume                   = {5},
    
      Doi                      = {10.1364/BOE.5.002963},
      ISSN                     = {2156-7085},
      Url                      = {http://www.opticsinfobase.org/boe/abstract.cfm?uri=boe-5-9-2963}
    }
  • Wieser, Wolfgang and Draxinger, Wolfgang and Klein, Thomas and Karpf, Sebastian and Pfeiffer, Tom and Huber, Robert: A 4-D OCT Engine with 1 GVoxel/s. Optics and Photonics News, no. 25, pp. 36, OSA, dec,, 2014
    BibTeX
    @Article{HU_2014_Wieser_b,
      Title                    = {{A 4-D OCT Engine with 1 GVoxel/s}},
      Author                   = {Wieser, Wolfgang and Draxinger, Wolfgang and Klein, Thomas and Karpf, Sebastian and Pfeiffer, Tom and Huber, Robert},
      Journal                  = {Optics and Photonics News},
      Year                     = {2014},
    
      Month                    = dec,
      Number                   = {12},
      Pages                    = {36 },
      Volume                   = {25},
    
      Publisher                = {OSA},
      Url                      = { http://www.osa-opn.org/home/articles/volume_25/december_2014/extras/a_4-d_oct_engine_with_1_gvoxel_s/#.VcH21Pl5raw}
    }