Conference presentation

 

 Oral Presentations

2018

1.    Miura Y, Basic of minimally-invasive retinal laser treatment - principle of mechanism of action and cellular response (Japanese), The 1st conference of Japan Minimally Invasive Retinal Laser Treatment, Dezember 2018, Kyoto

2.    Miura Y, Kern K, Brinkmann R. Influence of the inhibition of VEGF receptor 2 on the responses of cultured RPE cells to the laser-induced sublethal hyperthermia. LIGHT2018, Oct 2018, Chicago.  

3.    Miura Y, Hutfilz A, Sonntag S, Lewke B, Grisanti S, Brinkmann R. Änderung der Autofluoreszenzlebensdauer von ex-vivo RPE während der Wundheilung nach Laserbestrahlung. DOG. Sep 2018, Bonn.   

 4.   Miura Y. Selektive Retina Therapie (SRT) -klinische Ergebnisse. Lübecker Augenärztliche Fortbildung. Jun 2018, Travemünde, Lübeck.

5.   Miura Y. evaluation of mitochondrial function of the retinal tissues with FLIO
    FLIM2018, June 2018,Berlin

6.   Sonntag S., Hutfilz A, Lewke B, Grisanti S, Brinkmann R, Miura Y. Autofluoreszenzlebensdauer von ex-  vivo RPE während der Wundheilung nach Laserbestrahlung.68th Annual conference of  Vereinigung   Norddeutscher Augenärzte -VNDA- June 2018, Braunschweig.

7.   Miura Y, Lewke B, Wenig D, Grisanti S, Brinkmann R. „Change in fluorescence lifetime of retinal      pigment epithelium under oxidative stress” (japanese) Japanese Ophthalmology Congress. April 2018, Osaka, Japan.

8.    Inagaki K, Schmarbeck B, Bliedtner K, Hutfilz A, Ohkoshi K, Brinkmann R, Miura Y.
Comparison of damage area size between continuous wave laser and micropulse laser using ex-vivo RPE. [Japanisch] Japanese Ophthalmology Congress. April 2018, Osaka, Japan.

9.    Miura Y. Fluorescence lifetime imaging  of the ocular fundus tissues. 3D Lab-Exchange Program. Mar. 2018, Bonn.

2017

1. Miura Y. Fluorescence lifetime of retinal pigment epithelium. RRM (Retina Research Meeting) 2017. Dec.2017, Tokyo Japan.

2. Miura Y, Lewke B, Blimke N, Wenig D, Kern K, Grisanti S, Brinkmann R. Alteration of the fluorescence lifetime of the retinal pigment epithelium under oxidative stress. Annual conference of German Ophthalmology Society (DOG). Sep 2017, Berlin.

 3. Miura Y, Kern K, Beier S, Brinkmann R. Role of HSP70 and TRPV1 in cell survival and functions of RPE cells following thermal irradiations with different temperature increases. LIGHT 2017 (3rd Conference of International Retinal Laser Society). Sep 2017, Barcelona, Spain

4. Miura Y, Lewke B, Blimke N, Kern K, Grisanti S, Brinkmann R. Fluoreszenzlebensdauer -Ophthalmoskopie (FLIO) des ex-vivo retinalen Pigmentepithels unter oxidativem Stress. 67th Annual conference of Vereinigung Norddeutscher Augenärzte -VNDA- June 2017 Westerland, Germany


5. Miura Y, Blimke N, Britta L, Kern K, Pruessner J, Weng D, Huettmann G, Brinkmann R. Monitoring of wound healing of ex-vivo retinal pigment epithelium with fluorescence lifetime imaging Ophthalmoscopy (FLIO). Japanese Ophthalmology Congress. April 2017, Tokyo, Japan

2016

5. Miura Y. FLIM in retinal cell pathology. Conference on ADFLIM (Advanced Fluorescence Imaging Methods) Oct 2016, Dagomys - Sochi, Russi.

6. Miura Y. Investigation of ex-vivo retina with fluorescence lifetime imaging ophthalmoscopy (FLIO). FLIM 2016, Jun 2016, Prague.
7. Blimke N, Prussner J, Schneider C, Wenig D, Grisanti S, Brinkmann R, Miura Y. Ex-vivo investigations of metabolic changes of retinal pigment epithelium cells using Fluorescence lifetimeimaging ophthalmoscopy (FLIO). 29th Annual conference of the German Retina Society. June 2016, Berlin.
8. Miura Y. Cellular effect of thermal stimulation. Special interest group (SIG) Meeting an der ARVO Kongress, May 2016, Seattle.
9. Miura Y. Retinal thermotherapy -functional manipulation of retinal cells through non-lethal thermal laser irradiation (Japanisch). Guest speaker in the seminar of Japanese association of scientists in Singapore (JASS). March 2016, Singapur.

2015

10. Miura Y, Brinkmann R. Cell response determinants in laser-induced thermal impacts. Combined Biophysics and Human Performance review. 5. Nov 2015, San Antonio, USA.
11. Miura Y, Adler S, Beck E, Kern K, Blimke N, Pruessner J, Huettmann G, Roy S, Brinkmann R. Monitoring of high glucose-induced cell metabolic changes of retinal microvascular endothelial cells using fluorescence lifetime imaging microscopy. Annual conference of German Ophthalmology Society (DOG). Oct 2015, Berlin.
12. Kern K, Pruessner J, Weng D, Brinkmann R, Miura Y. Einfluss subletaler Hyperthermie auf die intra-/extrazelluläre Proteostase von RPE-Zellen. Annual conference of German Ophthalmology Society (DOG). Oct 2015, Berlin.
13. Miura Y, Kern K, Pruessner J, Weng D, Adler S, Brinkmann R. Anti-oxidant and anti-angiogenic potentials of laser-induced sublethal hyperthermia on retinal pigment epithelial cells. European Conference of Biomedical Optics (ECBO). June 2015, München.

 

2014

14. Miura Y. Fluorescnece lifetime imaging of retinal microvascular enfothelial cells under high glucose conditions [Japanisch].Jahrestagung der japanischen vitreoretinalen Gesellschaft. Nov 2014, Osaka, Japan.

15. Miura Y. Cellular effects of retinal laser irradiation. Annual conference of German Ophthalmology Society (DOG). Symposium "Koagulation heute". Sep 2014, Leipzig.

16. Miura Y, Huettmann G, Szaszak M, Koop N, Brinkmann R. Two-Photon Microscopy and Fluorescence Lifetime Imaging of the Retinal Pigment Epithelium and the Photoreceptor Outer Segments under Lipid Peroxidation. World Ophthalmology Congress 2014. Apr. 2014, Tokyo, Japan

17. Miura Y. Two-Photon Microscopy and Fluorescence Lifetime Imaging of the Retinal Pigment Epithelium under oxidative stress. Ophthalmology-2014. Jul 2014, Baltimore, USA

2013

18. Miura Y. Two-photon microscopy and fluorescence lifetime imaging microscopy [Japanese]. Seminar talk at Eye clinic in the Osaka City University. Dez. 2013. Osaka, Japan
19. Miura Y. Oxidative stress and retinal diseases. Oberseminar at the Institute of Biomedical Optics, Universität zu Lübeck. Nov. 2013
20. Miura Y, Fritz I, Grisanti S, Rudolf M. Effect of Apolipoprotein A1 (Apo A1)-Mimetic Peptides on Cultured RPE Cells. Annual Conference of the German Retina Society. Sep. 2013, Hamburg.

21. Miura Y, Mohi A, Aherrahrou Z,Grisanti S, Rudolf M. Die orale Verabreichung von Apolipoprotein A1-mimetisches Peptid D-4F reduziert die Akkumulation von Neutrallipiden in der Bruchmembran von Mäusen. 63. Tagung der Vereinigung Norddeutscher Augenärzte. Jun.2013, Westerland.

22. Miura Y, Fritz I, Grisanti S, Rudolf M. Effekt von Apolipoprotein A1-mimetischen Peptiden auf kultivierte RPE-Zellen. 63. Tagung der Vereinigung Norddeutscher Augenärzte. Jun.2013. Westerland.
23. Miura Y. New concepts for AMD treatment. Oberseminar at the Institute of Biomedical Optics, Universität zu Lübeck. Jan. 2013.

2012

24. Miura Y, Huettmann G, Steven P, Szaszak M, Brinkmann R. Two-photon excited autofluorescence in retinal pigment epithelial cells and photoreceptor outer segments induced by lipid peroxidation. World Ophthalmology Congress 2012. Feb 2012, Abu Dhabi. 2011

25. Miura Y. Two photon microscopy and FLIM of chorioretinal tissues. Oberseminor of the Institute of Biomedical Optics, Universität zu Lübeck. Nov 2011, Lübeck.

 

2010

26. Miura Y, Orzekowsky-Scgrieder R, Koop N, Steven P, Szaszak M, Huettmann G, Kohno T, Shiraki K, Brinkmann R. Autofluorescence in RPE cells around photocoagulation spots. [Japanese]. Annual conference of Japanese vitreoretinal society. Nov 2010, Osaka, Japan.
27. Miura Y, Orzekowsky R, Koop N, Steven N, Szaszak M, Huettmann G, Brinkmann R. Appearance of autofluorescence in RPE cells around photocoagulation spots. FLIM symposium. "Fluorescence Lifetime Imaging of the Human Retina". Sep 2010, Ilmenau.
28. Miura Y, Treumer F, Klettner A, Hillenkamp J, Brinkmann R, Birngruber R, Roider J. VEGF and PEDF secretions over time following various laser irradiations on an RPE organ culture. World Ophthalmology Congress 2010. June 2010, Berlin. 2009.
29. Miura Y. Investigations on RPE cell/organ cultures. Oberseminor of the Institute of Biomedical Optics, Universität zu Lübeck. Dec 2009, Lübeck.
30. Miura Y, Treumer F, Klettner A, Hillenkamp J, Brinkmann R, Birngruber R, Roider J. Laser power-dependent expression of vascular endothelial growth factor (VEGF) by porcine RPE after photocoagulation. Annual conference of German Ophthalmology Society (DOG). Sep 2009, Berlin.

31. Miura Y. Auswirkungen verschiedener Anti-VEGF-Medikamente auf das RPE am Beispiel eines experimentellen RPE-Modells. Annual conference of German Ophthalmology Society (DOG). Symposium "Pathogenese und Therapie von subretinalen und retinalen Neovaskularisationen: vom Molekül zur klinischen Manifestation" Sep 2009, Berlin. 2008
32. Miura Y, Roider J. Triamcinolone acetonide protects RPE tight junctions from oxidative stress. Annual conference of German Ophthalmology Society (DOG). Sep 2008, Berlin.

Poster presentations

2018

1. Hirayama K, Yamamoto M, Takeya K, Theisen-Kunde D, Miura Y, Brinkmann R, Honda S
Choroidal thickness after selective retina therapy for prolonged central serous chorioretionpaty
(Japanese), The 72nd Annual Congress of Japan Clinical Ophthalmology, Oct. 2018, Tokio, Japan

2. Miura Y, Hutfilz A, Sonntag S, Lewke B, Grisanti S, Brinkmann R
Change of RPE’s autofluorescence lifetime during wound healing after laser irradiation, EURETINA, Sep.2018, Wien

3. Hirayama K, Yamamoto M, Kohno T, Theisen-Kunde D, Miura Y, Brinkmann R, Shiraki K
Predictive factors of selective retina therapy for diabetic macular edema, ARVO Meeting , May 2018, Honululu, USA

4. Honda S, Yamamoto M, Kohno T, Hirayama K, Kyo A, Theisen-Kunde D, Miura Y, Brinkmann R, Shiraki Electroretinopgraphy after long-term follow-up of selective retina therapy for macular edema, ARVO Meeting, , Honululu, USA, May 2018

5. Brinkmann R, Inagaki K, Schmarbeck B, Hutfilz A, Bliedtner K, Ohkoshi K, Miura Y
Comparison and analysis of micropulse laser and continuous wave laser application on retinal pigment epithelium (RPE) ex vivo, ARVO Meeting, May 2018, Honolulu, USA

6. Miura Y, Hutfiilz A, Lewke B, Sonntag S, Coelius C, Grisanti S, Brinkmann R. Fluorescence Lifetime Imaging Ophthalmoscopy of ex-vivo retinal pigment epithelium after selective laser irradiation. ARVO Meeting. May 2018, Honolulu USA.

7. Kern K, Schaefer R, Mertineit C, Brinkmann R, Miura Y. Influence of thermal laser irradiation on cell proliferation and wound healing in primary RPE cell cultures. ARVO annual meeting. May 2018, Honolulu USA:

2017

1. Miura Y, Blimke N, Kern K, Weng D, Pruessner J, Huettmann G, Brinkmann R. Fluorescence lifetime measurements during laser-induced wound healing of retinal pigment epithelial cells. ARVO Meeting. May 2017. Baltimore, USA.
2. Kern K, Beier S, Brinkmann R, Miura Y. Influence of the TRPV-1 channel and HSP70 on RPE cell survival after transient temperature rise. ARVO Meeting. May 2017. Baltimore, USA. 2016

2016

3. Miura Y, Blimke N, Pruessner J, Baade A, Brinkmann R. Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) for the detection of thermal laser-induced tissue metabolic changes. Annual Conference of German Ophthalmology Society (DOG). Sep 2016, Berlin.
4. Kern K, Matrineit CL, Beier S, Pruessner J, Brinkmann R, Miura Y. Die Rolle von HSP70 bei Hyperthermie des retinalen Pigmentepithels - Implikationen für die thermische Stimulation der Retina (TS-R) -. Annual Conference of German Ophthalmology Society (DOG). Sep 2016, Berlin.
5. Blimke N, Pruessner J, Alt L, Huettmann G, Brinkmann R, Miura Y. Ex-vivo assessment of metabolic alterations of retinal pigment epithelial cells using Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). ARVO Meeting. May 2016. 253-B0259. Seattle, USA.
6. Pruessner J, Blimke N, Alt L, Huettmann G, Brinkmann R, Miura Y. Fluorescence Lifetime Imaging Ophthalmoscopy of in-vitro retinal pigment epithelial cells under different glucose conditions. ARVO Meeting. May 2016. 266-B0272. Seattle, USA.
7. Miura Y, Kern K, Pruessner J, Brinkmann R. Subcellular calcium dynamics during transient sublethal hyperthermia and subsequent protein expressions in retinal pigment epithelial cells. ARVO Meeting. May 2016. 5849-C0085. Seattle, USA.

8. Ranjbar M, Brinkmann MP, Zapf D, Miura Y, Rudolf M, Grisanti S. Fc receptor inhibition reduces susceptibility to oxidative stress in human RPE cells treated with bevacizumab, but not aflibercept. ARVO Meeting. May 2016. 3357-D0160. Seattle, USA.
9. Okada R, Yamamot M, Hirayama K, Yasui A, Kohno T, Theisen-Kunde D, Miura Y, Brinkman R, Shiraki K. Fundus Autofluorescence at Test Irradiation Spots after Selective Retina Therapy for Central Serous Chorioretinopathy. ARVO Meeting. May 2016. 5345-B0016. Seattle, USA.

 

2015

10. Miura Y, Beck E, Huttmann G, Roy S, Brinkmann R. Fluorescence lifetime imaging microscopy on retinal microvascular endothelial cells under high glucose conditions. ARVO Meeting. May 2015. E-abstract 5943 - A0114. Denver, USA.
11. Brinkmann R, Koinzer S, Baade A, Schwarzer B, Schlott K, Miura Y, Roider Y. Automatically Power Controlled Retinal Photocoagulation. ARVO Meeting. May, 2015. E-abstract 5666 - C0053. Denver, USA. 2014
12. Brinkmann MP, Miura Y, Rudolf M, Grisanti S, Ranjbar M. Pharmacodynamics of VEGF antagonists in human RPE in vitro. ARVO Meeting. April 30, 2014;55:E-abstract 1945. Orlando USA. 2013
13. Rudolf M, Mohi A, Aherrahrou Z, Grisanti S, Miura Y. Oral administration of Apolipoprotein A-I mimetic peptide D-4F reduces lipid accumulation in murine Bruch's membrane (BrM). ARVO Meeting. May, 2013;54:E-abstract 1714. Seattle, USA.
14. Yasui A, Yamamoto M, Kohno T, Yoneda T, Yoshida Y, Iwami H, Theisen-Kunde D, Miura Y, Brinkmann R, Shiraki K. Focal Retinal Sensitivity Before and After Selective Retina Therapy for Central Serous Chorioretinopathy. ARVO Meeting. May, 2013; 54:E-abstract 4130. Seattle, USA.
15. Miura Y, Fritz I, Grisanti S, Rudolf M. Effect of Apolipoprotein A1-mimetic peptides on cell viability of cultured retinal pigment epithelial cells. ARVO Meeting. May, 2013; 54:E-abstract 3296. Seattle, USA.
16. Yamamoto M, Kohno T, Yoneda T, Yoshida Y, Iwami H, Yasui A, Theisen-Kunde D, Miura Y, Brinkmann R, Shiraki K. Six-month Report of Selective Retina Therapy on Central Serous Chorioretinopathy in Japanese Patients. ARVO Meeting. May, 2013; 54:E-abstract 4134. Seattle, USA.

17. Brinkmannb R, Iwami H, Pruessner J, Danicke V, Miura Y. Temperature-dependent response of retinal pigment epithelial cells to laser irradiation. ARVO Meeting. May, 2013;54:E-abstract 1809. Fort Lauderdale, USA. 2012
18. Iwami H, Ptaszynski L, Danicke V, Brinkmann R, Miura Y. Sublethal Hyperthermia-induced Vascular Endothelial Growth Factor Secretion And Its Contribution To Adoptive Response Of Retinal Pigment Epithelial Cell. ARVO Meeting. March, 2012;53:E-abstract 4782. Fort Lauderdale, USA.
19. Yoshimoto K, Yamamoto M, Kohno T, Yoneda T, Yoshida Y, Fritz A, Theisen-Kunde D, Miura Y, Brinkmann R., Shiraki K. Detection Of Sub-threshold Laser Irradiation Spots With Various Fundus Imaging Methods And Its Correlation With Irradiation Energy And Optoacoustic Values In Selective Retina Therapy. ARVO Meeting. March, 2012; 53:E-abstract 5198. Fort Lauderdale, USA.
20. Yamamoto M, Kohno T, Yoshida Y, Yoneda T, Iwami H, Fritz A, Theisen-Kunde D, Miura Y, Brinkmann R., Shiraki K. Selective Retina Therapy for Patients with Central Serous Chorioretinopathy in Japan. ARVO Meeting. March, 2012;53:E-abstract 5222. Fort Lauderdale, USA.
21. Miura Y, Huettmann G, Szaszak M, Orzekowsky-Schroeder R, Koop N, Steven P, Brinkmann R. Two-photon Microscopy and Fluorescence Lifetime Analysis of Lipid Peroxidation Product in Photoreceptor Outer Segment and in Retinal Pigment Epithelial Cell. ARVO Meeting. March, 2012;53:E-abstract 1130. Fort Lauderdale, USA. 2011
22. Brinkmann R, Schlott K, Koinzer S, Bever M, Baade A, Ptaszynski L, Miura Y, Roider J, Birngruber R. Temperature Controlled Retinal Photocoagulation In Vivo. ARVO Meeting. April, 2011;52:E-abstract 547. Fort Lauderdale, USA.
23. Koinzer SO, Bever M, Schlott K, Ptaszynski L, Baade A, Ludt S, Miura Y, Birngruber R, Brinkmann R, Roider J. Real Time Temperature Measurement During Laser Photocoagulation Of Human Retina. ARVO Meeting. April, 2011;52:E-abstract 551. Fort Lauderdale, USA.
24. Miura Y, Huttmann G, Orzekowsky-Schroeder R, Steven P, Szaszak M, Koop N, Birngruber R, Brinkmann R. Investigations of Two-photon Excited Bright Autofluorescent Granules in the RPE Cells Around Photocoagulation Spots. ARVO Meeting. April, 2011;52:E-abstract 926. Fort Lauderdale, USA. 2010
25. Miura Y, Treumer F, Klettner A, Hillenkamp J, Brinkmann R, Birngruber R, Roider J. Vegf and Pedf Secretions Over Time Following Various Laser Irradiations on an Rpe Organ Culture. ARVO Meeting. April, 2010;51:E-abstract 469. Fort Lauderdale, USA. 2009
26. Treumer F, Miura Y, Klettner A, Brinkmann R, Birngruber R, Roider J, Hillenkamp J. The Effect of Selective Retina Therapy (SRT) on the Expression of Matrixmetalloproteinase-2 (MMP-2) and Vascular Endothelial Growth Factor (VEGF) by Cultivated Porcine RPE-choroid Explants. ARVO Meeting. April, 2009;50:E-abstract 3411. Fort Lauderdale, USA.
27. Miura Y, Treumer F, Klettner A, Hillenkamp J, Brinkmann R, Birngruber R, Roider J. Laser Power-Dependent Expression of Vascular Endothelial Growth Factor (VEGF) by Porcine RPE After Photocoagulation. ARVO Meeting. April, 2009;50: E-abstract 201. Fort Lauderdale, USA.

2008

Miura Y, Klettner A, Roider J. Bevacizumab (Avastin) and Ranibizumab (Lucentis) Enhance the Permeability of Cultured Retinal Pigment Epithelium, but Not in the Presence of Triamcinolone Acetonide. ARVO Meeting