@article{RN5426,
   author = {Aşırım, Özüm Emre;Huber, Robert and Jirauschek, Christian},
   title = {Influence of the linewidth enhancement factor on the signal pattern of Fourier domain mode-locked lasers},
   journal = {Applied Physics B},
   volume = {128},
   number = {12},
   pages = {218},
   ISSN = {1432-0649},
   DOI = {10.1007/s00340-022-07933-5},
   url = {https://doi.org/10.1007/s00340-022-07933-5},
   year = {2022},
   type = {Journal Article}
}

@article{JACOBI2022S288,
title = {620 Screening an inhibitor library for new drug candidates to promote wound healing},
journal = {Journal of Investigative Dermatology},
volume = {142},
number = {12, Supplement },
pages = {S288},
year = {2022},
note = {ESDR 2022 Meeting Abstract Supplement},
issn = {0022-202X},
doi = {https://doi.org/10.1016/j.jid.2022.09.637},
url = {https://www.sciencedirect.com/science/article/pii/S0022202X22025714},
author = {C. Jacobi and M. Göb and R. Huber and R.J. Ludwig and J.E. Hundt}
}

@article{RN5359,
   author = {Ha-Wissel, L.;Yasak, H.;Huber, R.;Zillikens, D.;Ludwig, R. J.;Thaçi, D. and Hundt, J. E.},
   title = {Case report: Optical coherence tomography for monitoring biologic therapy in psoriasis and atopic dermatitis},
   journal = {Front Med (Lausanne)},
   volume = {9},
   pages = {995883},
   ISSN = {2296-858X (Print)
2296-858x},
   DOI = {10.3389/fmed.2022.995883},
   year = {2022},
   type = {Journal Article}
}

@article{Strenge-2022,
   author = {Strenge, P.;Lange, B.;Grill,C.;Danicke,V.;Theisen-Kunde, D.;Hagel, C.;Spahr-Hess, S.;;Bonsanto, Matteo M.;Handels, H.; and Huber, R.;Brinkmann, R.},
   title = {Differentiation of different stages of brain tumor infiltration using optical coherence tomography: Comparison of two systems and histology},
   journal = {Frontiers in Oncology},
Keywords = {AG-Huber_FDML, AG-Huber_OCT, brain, tumor, glioblastoma multiforme, OCT, neural network, attenuation (absorption)
coefficient, optical coherence tomography},
   DOI = {https://doi.org/10.3389/fonc.2022.896060},
   url = {https://www.frontiersin.org/articles/10.3389/fonc.2022.896060/full},
   year = {2022},
   type = {Journal Article}
}

@article{Grill2022,
  doi = {10.1038/s42005-022-00960-w},
  year = {2022},
  publisher = {Springer Science and Business Media {LLC}},
  volume = {{5}},
  number = {{1}},
  author = {C. Grill, T. Bl\"{o}mker, M. Schmidt, D. Kastner, T. Pfeiffer, J.P. Kolb, W. Draxinger, S. Karpf, C. Jirauschek and R. Huber},
  title = {Towards phase-stabilized Fourier domain mode-locked frequency combs},
  journal = {{Communications Physics}},
keywords={AG-Huber_FDML, FDML, Fourier domain mode locking, phase, frequency comb, coherence, beating}
}

@article{Strenge2022,
   author = {Strenge, P;Lange, B;Grill, C;Draxinger, W;Danicke, V;Theisen-Kunde, D;Hagel, C;Spahr-Hess, S;Bonsanto, Matteo M.;Huber, R;Handels, H and Brinkmann, R},
   title = {Registration of histological brain images onto optical coherence tomography images based on shape information},
keywords = {brain, glioblastoma multiforme, shape, OCT, optical coherence tomography, AG-Huber_OCT,},
   journal = {Physics in Medicine & Biology},
   ISSN = {0031-9155},
   url = {http://iopscience.iop.org/article/10.1088/1361-6560/ac6d9d},
   year = {2022},
   type = {Journal Article}
}

@article{RN5328,
   author = {Pfäffle, C;Spahr, H;Gercke, K;Puyo, L;Höhl, S;Melenberg, D;Miura, Y;Hüttmann, G and Hillmann, D},
   title = {Phase-Sensitive Measurements of Depth-Dependent Signal Transduction in the Inner Plexiform Layer},
   journal = {Frontiers in Medicine},
   volume = {9},
   ISSN = {2296-858X},
   DOI = {10.3389/fmed.2022.885187},
keywords = {optoretinography, optical coherence tomography, phase-sensitive OCT, functional imaging, inner
plexiform layer, retina},
   url = {https://www.frontiersin.org/articles/10.3389/fmed.2022.885187},
   year = {2022},
   type = {Journal Article}
}

@inproceedings{10.1117/12.2612171,
author = {Madita G{\"o}b and Sazgar Burhan and Simon Lotz and Robert Huber},
title = {{Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT}},
volume = {11948},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI},
editor = {Joseph A. Izatt and James G. Fujimoto},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {1194807},
abstract = {We demonstrate ultra-large field of view OCT scanning using standard optics, a X-Y-galvanometer scanner and a synchronously driven motorized XYZ-positioning stage. The integration of a movable stage into our self-built 3.3 MHz- OCT system allows acquiring coherent ultra-large area images, fully leveraging the high speed potential of our system. For fast OCT-angiography, one galvanometer axis scanner is driven in a repetitive sawtooth pattern, fully synchronized to the movement of the linear stage, to obtain multiple measurements at each position. This technique requires exact synchronization, precise repositioning, and uniform movements with low tolerances to ensure a minimum revisitation error. We analyze error and performance of our setup and demonstrate angiographic imaging.},
keywords = {Optical Coherence Tomography, Fourier Domain Mode Locking, FDML, Optical Coherence Angiography, OCTA, Medical optics and biotechnology, Medical imaging, Three-dimensional image acquisition, Scanners, Microscopy},
year = {2022},
doi = {10.1117/12.2612171},
URL = {https://doi.org/10.1117/12.2612171}
}

@inproceedings{10.1117/12.2608773,
author = {M. Klufts and S. Lotz and M. Bashir and S. Karpf and R. Huber},
title = {{Ultra-high-accuracy chromatic dispersion measurement in optical fibers}},
volume = {11997},
booktitle = {Optical Components and Materials XIX},
editor = {Shibin Jiang and Michel J. F. Digonnet},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {119970L},
abstract = {The chromatic dispersion in optical fibers is a key property for applications where a broadband light source is used and the timing of each individual wavelength is crucial. Counteracting the timing offset introduced by the fiber is a challenge in many applications especially in mode locked lasers. The dispersion parameters need to be measured with high precision. The length of the fiber, the temperature, and the used wavelength will highly impact the amount of dispersion and the accuracy of the measurement. We developed an ultra-high-accuracy dispersion measurement setup at 1080 ± 50 nm considering all the parameters that may influence the measurement. It is based on a home-built wavelength tunable laser where the output is modulated by an electro-optical modulator connected to a 24 GSamples/s arbitrary waveform generator to a complex pattern consisting of pulses and a 4 GHz sine wave. After passing through the fiber the signal is measured with an 80 GSamples/s real time oscilloscope. The fiber’s temperature is controlled to allow for reproducible measurements over several days and we achieve timing measurement accuracies down to ~200 fs. We also present the performance of the setup at ~850 nm. We will discuss and quantify all effects which can negatively impact the system accuracy and we will report on more cost-effective options using lower performance equipment.},
keywords = {Dispersion measurement, Chromatic dispersion, fiber dispersion measurement, optical component characterization, tunable laser, FDML},
year = {2022},
doi = {10.1117/12.2608773},
URL = {https://doi.org/10.1117/12.2608773}
}

@article{Deen2022,
   author = {Deen, A D;Van Beusekom, H M. M.;Pfeiffer, T;Stam, M;Kleijn, D De;Wentzel, J;Huber, R;Van Der Steen, A F. W.;Soest, G Van and Wang, T},
   title = {Spectroscopic thermo-elastic optical coherence tomography for tissue characterization},
   journal = {BioOptExpr},
keywords = {AG-Huber, Endoscopic imaging, Image processing, Image quality, Imaging techniques, Optical imaging, Tissue characterization},
   volume = {13(3)},
   pages = {1430-1446},
   DOI = {10.1364/BOE.447911},
    year = {2022},
   type = {Journal Article}
}

@article{Gob:22,
author = {Madita G\"{o}b and Tom Pfeiffer and Wolfgang Draxinger and Simon Lotz and Jan Philip Kolb and Robert Huber},
journal = {Biomed. Opt. Express},
keywords = {High speed imaging; Image processing; Image quality; In vivo imaging; Range imaging; Vertical cavity surface emitting lasers},
number = {2},
pages = {713--727},
publisher = {Optica Publishing Group},
title = {Continuous spectral zooming for in vivo live 4D-OCT with MHz A-scan rates and long coherence},
volume = {13},
month = {Feb},
year = {2022},
url = {https://opg.optica.org/boe/abstract.cfm?URI=boe-13-2-713},
doi = {10.1364/BOE.448353},
abstract = {We present continuous three-dimensional spectral zooming in live 4D-OCT using a home-built FDML based OCT system with 3.28 MHz A-scan rate. Improved coherence characteristics of the FDML laser allow for imaging ranges up to 10 cm. For the axial spectral zoom feature, we switch between high resolution and long imaging range by adjusting the sweep range of our laser. We present a new imaging setup allowing for synchronized adjustments of the imaging range and lateral field of view during live OCT imaging. For this, a novel inline recalibration algorithm was implemented that enables numerical k-linearization of the raw OCT fringes for every frame instead of every volume. This is realized by acquiring recalibration data within the dead time of the raster scan at the turning points of the fast axis scanner. We demonstrate in vivo OCT images of fingers and hands at different resolution modes and show real three-dimensional zooming during live 4D-OCT. A three-dimensional spectral zooming feature for live 4D-OCT is expected to be a useful tool for a wide range of biomedical, scientific and research applications, especially in OCT guided surgery.},
}

@article{Yashin-2022,
   author = {Yashin, K;Bonsanto, M M;Achkasova, K;Zolotova, A;Wael, Al-M;Kiseleva, E;Moiseev, A;Medyanik, I;Kravets, L;Huber, R;Brinkmann, R and Gladkova, N},
   title = {OCT-Guided Surgery for Gliomas: Current Concept and Future Perspectives},
   journal = {Diagnostics},
   volume = {12},
   number = {2},
   pages = {335},
   ISSN = {2075-4418},
keywords = {AG-Huber; optical coherence tomography; brain imaging; neurosurgical guidance; brain tumor; minimally invasive theranostics; intraoperative imaging},
   url = {https://www.mdpi.com/2075-4418/12/2/335},
   year = {2022},
   type = {Journal Article}
}

@INPROCEEDINGS{9894816,
  author={Aşırım, Ö. E. and Huber, R. and Jirauschek, C.},
  booktitle={2022 International Conference on Numerical Simulation of Optoelectronic Devices (NUSOD)}, 
  title={Effect of Self-Phase Modulation on The Signal Quality of Fourier Domain Mode-Locked Lasers}, 
  year={2022},
  volume={},
  number={},
  pages={67-68},
  doi={10.1109/NUSOD54938.2022.9894816}}

Optical coherence elastography (OCE), a functional extension of optical coherence tomography (OCT), visualizes tissue strain to deduce the tissue’s biomechanical properties. In this study, we demonstrate intravascular OCE using a 1.1 mm motorized catheter and a 1.6 MHz Fourier domain mode-locked OCT system. We induced an intraluminal pressure change by varying the infusion rate from the proximal end of the catheter. We analysed the pixel-matched phase change between two different frames to yield the radial strain. Imaging experiments were carried out in a phantom and in human coronary arteries in vitro. At an imaging speed of 3019 frames/s, we were able to capture the dynamic strain. Stiff inclusions in the phantom and calcification in atherosclerotic plaques are associated with low strain values and can be distinguished from the surrounding soft material, which exhibits elevated strain. For the first time, circumferential intravascular OCE images are provided side by side with conventional OCT images, simultaneously mapping both the tissue structure and stiffness.

@article{Freidank2022,
   author = {Freidank, S;Vogel, A and Linz, N},
   title = {Mechanisms of corneal intrastromal laser dissection for refractive surgery: ultra-high-speed photographic investigation at up to 50 million frames per second},
   journal = {BioOptExpr},
   volume = {13 (5)},
   
   pages = {3056-3079},
   DOI = {10.1364/BOE.455926},

   year = {2022},
   type = {Journal Article}
}

@article{Kohlfarber2022,
   author = {Kohlfaerber, T;Pieper, M;Münter, M;Holzhausen, C;Ahrens, M;Idel, C;Bruchhage, K-L;Leichtle, A;König, P;Hüttmann, G and Schulz-Hildebrandt, H},
   title = {Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways},
   journal = {Biomedical Optics Express},
   volume = {13 (6)},
   pages = {3211-3223},
   DOI = {10.1364/BOE.456104},
  
   year = {2022},
   type = {Journal Article}
}

@article{Schaller2022,
   author = {Schaller, M;Wilson, M;Kleyman, V;Mordmüller, M;Brinkmann, R;Müller, M. A. and Worthmann, K},
   title = {Parameter estimation and model reduction for model predictive control in retinal laser treatment},
   journal = {Control Engineering Practice},
   volume = {128},
   pages = {105320},
   ISSN = {0967-0661},
   DOI = {https://doi.org/10.1016/j.conengprac.2022.105320},

   year = {2022},
   type = {Journal Article}
}

@article{Musial-2022,
   author = {Musial, G;Kohlfaerber, T;Ahrens, M;Schulz-Hildebrandt, H;Steven, P and Hüttmann, G},
   title = {Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride},
   journal = {Translational Vision Science & Technology},
keywords = {toxicity; optical coherence tomography; benzalkonium chloride},
   volume = {11(5)},

   pages = {28-28},
   ISSN = {2164-2591},
   DOI = {10.1167/tvst.11.5.28},
   url = {https://doi.org/10.1167/tvst.11.5.28},
   year = {2022},
   type = {Journal Article}
}

@article{Liang2022,
   author = {Liang, X-X and Vogel, A},
   title = {Probing neuronal functions with precise and targeted laser ablation in the living cortex: comment},
   journal = {Optica},
   volume = {9(8)},
   keywords = {Attenuation coefficient, Femtosecond lasers, Laser ablation, Laser irradiation, Numerical simulation, Thermal effects},
   pages = {868-871},
   DOI = {10.1364/OPTICA.454469},  
   year = {2022},
   type = {Journal Article}
}

@article{GOODWIN2022,
title = {Detection of subtle cartilage and bone tissue degeneration in the equine joint using polarisation-sensitive optical coherence tomography},
journal = {Osteoarthritis and Cartilage},
year = {2022},
issn = {1063-4584},
doi = {https://doi.org/10.1016/j.joca.2022.04.006},
author = {M. Goodwin, M. Klufts, J. Workman, A. Thambyah and F. Vanholsbeeck},
keywords = {Optical coherence tomography, Polarisation-sensitive optical coherence tomography, Osteoarthritis},
abstract = {Summary
Objective
To explore the ability of polarisation-sensitive optical coherence tomography (PS-OCT) to rapidly identify subtle signs of tissue degeneration in the equine joint.
Method
Polarisation-sensitive optical coherence tomography (PS-OCT) images were systematically acquired in four locations along the medial and lateral condyles of the third metacarpal bone in five dissected equine specimens. Intensity and retardation PS-OCT images, and anomalies observed therein, were then compared and validated with high resolution images of the tissue sections obtained using Differential Interference contrast (DIC) optical light microscopy.
Results
The PS-OCT system was capable of imaging the entire equine osteochondral unit, and allowed delineation of the three structurally differentiated zones of the joint, that is, the articular cartilage matrix, zone of calcified cartilage and underlying subchondral bone. Importantly, PS-OCT imaging was able to detect underlying matrix and bone changes not visible without dissection and/or microscopy.
Conclusion
PS-OCT has substantial potential to detect, non-invasively, sub-surface microstructural changes that are known to be associated with the early stages of joint tissue degeneration.}
}

@article{von-der-Burchardt2022,
   author = {von der Burchard, C;Sudkamp, H;Tode, J;Ehlken, C;Purtskhvanidze, K;Moltmann, M;Heimes, B;Koch, P;Münst, M;vom Endt, M;Kepp, T;Theisen-Kunde, D;König, I;Hüttmann, G and Roider, J},
   title = {Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study},
   journal = {BMJ Open},
   volume = {12},
   number = {6},
   pages = {e055082},
   DOI = {10.1136/bmjopen-2021-055082},
   url = {http://bmjopen.bmj.com/content/12/6/e055082.abstract},
   year = {2022},
   type = {Journal Article}
}

@article{Miura2022,
   author = {Miura, Y;Inagaki, K;Hutfilz, A;Seifert, E;Schmarbeck, B;Murakami, A;Ohkoshi, K and Brinkmann, R},
   title = {Temperature Increase and Damage Extent at Retinal Pigment Epithelium Compared between Continuous Wave and Micropulse Laser Application},
   journal = {Life},
   volume = {12(9)},
  
   pages = {1313},
   ISSN = {2075-1729},
   url = {https://www.mdpi.com/2075-1729/12/9/1313},
   year = {2022},
   type = {Journal Article}
}

@article{Lange2022,
   author = {Lange, B;Ozimek, T;Wießmeyer, J R;Kramer, M W.;Merseburger, A S. and Brinkmann, R},
   title = {Theoretical and experimental evaluation of the distance dependence of fiber-based fluorescence and reflection measurements for laser lithotripsy},
   journal = {Biomedical Physics & Engineering Express},
   volume = {8},
   number = {5},
abstract = {Objectives. In laser lithotripsy, a green aiming beam overlying the infrared (IR) treatment radiation gives rise to reflection and fluorescence signals that can be measured via the treatment fiber. While stone autofluorescence is used for target detection, the condition of the fiber can be assessed based on its Fresnel reflection. For good applicability, fluorescence detection of stones should work even when the stone and fiber are not in direct contact. Fiber breakage detection, on the other hand, can be falsified if surfaces located in front of the fiber reflect light from the aiming laser back into it. For both applications, therefore, a fundamental investigation of the dependence of the signal amplitude on the distance between fiber and surface is important. Methods. Calculations of the signal drop of fluorescence or diffuse and specular reflection with increasing fiber distance were performed using ray tracing based on a simple geometric model for different fiber core diameters. Reflection signals from a mirror, diffuse reflector, human calculi, and porcine renal tissue placed in water were measured at varying distances (0–5 mm). For human calculi, fluorescence signals were recorded simultaneously. Results. The calculations showed a linear signal decrease down to ∼60% of the maximum signal (fiber in contact). The distance z at which the signal drops to for example 50% depends linearly on the diameter of the fiber core. For fibers used in lithotripsy and positioned in water, z50% ranges from 0.55 mm (200 μm core diameter) to 2.73 mm, (1 mm core diameter). The calculations were in good agreement with the experimental results. Conclusions. The autofluorescence signals of stones can be measured in non-contact mode. Evaluating the Fresnel signal of the end face of the fiber to detect breakage is possible unless the fiber is situated less than some millimeters to reflecting surfaces.},
keywords = {urolithiasis, laser lithotripsy, fluorescence, reflectance},
   pages = {055023},
   ISSN = {2057-1976},
   DOI = {10.1088/2057-1976/ac82c7},
   
   year = {2022},
   type = {Journal Article}
}

@article{Liang2022,
   author = {Liang, X-X;Linz, N;Freidank, S;Paltauf, G and Vogel, A},
   title = {Comprehensive analysis of spherical bubble oscillations and shock wave emission in laser-induced cavitation},
keywords = {bubble dynamics, cavitation, shock waves},
   journal = {Journal of Fluid Mechanics},
   volume = {940},
   pages = {A5},
   ISSN = {0022-1120},
   DOI = {10.1017/jfm.2022.202},
  
   year = {2022},
   type = {Journal Article}
}

@article{Schaller2022,
   author = {Schaller, M.;Kleyman, K.;Mordmüller, M.;Schmidt, C.;Wilson, M.;Brinkmann, R.;Müller, M.A. and Worthmann, K.},
   title = {Model predictive control for retinal laser treatment at 1 kHz},
   journal = {at - Automatisierungstechnik},
   volume = {70(11)},
   keywords = {model predictive control; real-time control;retinal photocoagulation},
   pages = {992-1002},
  
   url = {https://doi.org/10.1515/auto-2022-0030},
   year = {2022},
   type = {Journal Article}
}