Publikationen 2022

2022

  • M. Klufts, S. Lotz, M. Bashir, S. Karpf and R. Huber: Ultra-high-accuracy chromatic dispersion measurement in optical fibers. in Optical Components and Materials XIX, no. 11997, pp. 146 - 152, SPIE, 2022
    BibTeX Link
    @inproceedings{Klufts2022,
    author = {M. Klufts, S. Lotz, M. Bashir, S. Karpf and R. Huber},
    title = {{Ultra-high-accuracy chromatic dispersion measurement in optical fibers}},
    volume = {11997},
    booktitle = {Optical Components and Materials XIX},
    editor = {Shibin Jiang and Michel J. F. Digonnet},
    organization = {International Society for Optics and Photonics},
    publisher = {SPIE},
    pages = {146 -- 152},
    keywords = {AG-Huber_FDML, Dispersion measurement, Chromatic dispersion, fiber dispersion measurement, optical component characterization, tunable laser, FDML},
    year = {2022},
    
    url = {https://zenodo.org/record/6406367#.YkcF3TWxX8A},
    }
    
  • M. Göb, S. Burhan, S. Lotz and R. Huber: Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT. in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI, no. 11948, pp. 27 - 31, SPIE, 2022
    BibTeX Link
    @inproceedings{Goeb2022BiOS,
    author = {M. Göb, S. Burhan, S. Lotz and R. Huber},
    title = {{Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT}},
    volume = {11948},
    booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI},
    editor = {Joseph A. Izatt and James G. Fujimoto},
    organization = {International Society for Optics and Photonics},
    publisher = {SPIE},
    pages = {27 -- 31},
    keywords = {AG-Huber_FDML, AG-Huber_OCT, Optical Coherence Tomography, Fourier Domain Mode Locking, FDML, Optical Coherence Angiography, OCTA, Medical optics and biotechnology, Medical imaging, Three-dimensional image acquisition, Scanners, Microscopy},
    year = {2022},
    doi = {10.1117/12.2612171},
    }
  • C. Grill, T. Blömker, M. Schmidt, D. Kastner, T. Pfeiffer, J.P. Kolb, W. Draxinger, S. Karpf, C. Jirauschek and R. Huber: Towards phase-stabilized Fourier domain mode-locked frequency combs. Communications Physics, no. 5, Springer Science and Business Media LLC, 2022
    BibTeX Link
    @article{Grill2022,
      doi = {10.1038/s42005-022-00960-w},
      year = {2022},
      publisher = {Springer Science and Business Media {LLC}},
      volume = {{5}},
      number = {{1}},
      author = {C. Grill, T. Bl\"{o}mker, M. Schmidt, D. Kastner, T. Pfeiffer, J.P. Kolb, W. Draxinger, S. Karpf, C. Jirauschek and R. Huber},
      title = {Towards phase-stabilized Fourier domain mode-locked frequency combs},
      journal = {{Communications Physics}},
    keywords={AG-Huber_FDML, FDML, Fourier domain mode locking, phase, frequency comb, coherence, beating}
    }
  • Lange, B;Ozimek, T;Wießmeyer, J R;Kramer, M W.;Merseburger, A S. and Brinkmann, R: Theoretical and experimental evaluation of the distance dependence of fiber-based fluorescence and reflection measurements for laser lithotripsy. Biomedical Physics & Engineering Express, no. 8, pp. 055023, 2022
    BibTeX Link
    @article{Lange2022,
       author = {Lange, B;Ozimek, T;Wießmeyer, J R;Kramer, M W.;Merseburger, A S. and Brinkmann, R},
       title = {Theoretical and experimental evaluation of the distance dependence of fiber-based fluorescence and reflection measurements for laser lithotripsy},
       journal = {Biomedical Physics & Engineering Express},
       volume = {8},
       number = {5},
    abstract = {Objectives. In laser lithotripsy, a green aiming beam overlying the infrared (IR) treatment radiation gives rise to reflection and fluorescence signals that can be measured via the treatment fiber. While stone autofluorescence is used for target detection, the condition of the fiber can be assessed based on its Fresnel reflection. For good applicability, fluorescence detection of stones should work even when the stone and fiber are not in direct contact. Fiber breakage detection, on the other hand, can be falsified if surfaces located in front of the fiber reflect light from the aiming laser back into it. For both applications, therefore, a fundamental investigation of the dependence of the signal amplitude on the distance between fiber and surface is important. Methods. Calculations of the signal drop of fluorescence or diffuse and specular reflection with increasing fiber distance were performed using ray tracing based on a simple geometric model for different fiber core diameters. Reflection signals from a mirror, diffuse reflector, human calculi, and porcine renal tissue placed in water were measured at varying distances (0–5 mm). For human calculi, fluorescence signals were recorded simultaneously. Results. The calculations showed a linear signal decrease down to ∼60% of the maximum signal (fiber in contact). The distance z at which the signal drops to for example 50% depends linearly on the diameter of the fiber core. For fibers used in lithotripsy and positioned in water, z50% ranges from 0.55 mm (200 μm core diameter) to 2.73 mm, (1 mm core diameter). The calculations were in good agreement with the experimental results. Conclusions. The autofluorescence signals of stones can be measured in non-contact mode. Evaluating the Fresnel signal of the end face of the fiber to detect breakage is possible unless the fiber is situated less than some millimeters to reflecting surfaces.},
    keywords = {urolithiasis, laser lithotripsy, fluorescence, reflectance},
       pages = {055023},
       ISSN = {2057-1976},
       DOI = {10.1088/2057-1976/ac82c7},
       
       year = {2022},
       type = {Journal Article}
    }
    
  • Miura, Y;Inagaki, K;Hutfilz, A;Seifert, E;Schmarbeck, B;Murakami, A;Ohkoshi, K and Brinkmann, R: Temperature Increase and Damage Extent at Retinal Pigment Epithelium Compared between Continuous Wave and Micropulse Laser Application. Life, no. 12(9), pp. 1313, 2022
    BibTeX Link
    @article{Miura2022,
       author = {Miura, Y;Inagaki, K;Hutfilz, A;Seifert, E;Schmarbeck, B;Murakami, A;Ohkoshi, K and Brinkmann, R},
       title = {Temperature Increase and Damage Extent at Retinal Pigment Epithelium Compared between Continuous Wave and Micropulse Laser Application},
       journal = {Life},
       volume = {12(9)},
      
       pages = {1313},
       ISSN = {2075-1729},
       url = {https://www.mdpi.com/2075-1729/12/9/1313},
       year = {2022},
       type = {Journal Article}
    }
    
  • Deen, A D;Van Beusekom, H M. M.;Pfeiffer, T;Stam, M;Kleijn, D De;Wentzel, J;Huber, R;Van Der Steen, A F. W.;Soest, G Van and Wang, T: Spectroscopic thermo-elastic optical coherence tomography for tissue characterization. BioOptExpr, no. 13(3), pp. 1430-1446, 2022
    BibTeX Link
    @article{Deen2022,
       author = {Deen, A D;Van Beusekom, H M. M.;Pfeiffer, T;Stam, M;Kleijn, D De;Wentzel, J;Huber, R;Van Der Steen, A F. W.;Soest, G Van and Wang, T},
       title = {Spectroscopic thermo-elastic optical coherence tomography for tissue characterization},
       journal = {BioOptExpr},
    keywords = {AG-Huber, Endoscopic imaging, Image processing, Image quality, Imaging techniques, Optical imaging, Tissue characterization},
       volume = {13(3)},
       pages = {1430-1446},
       DOI = {10.1364/BOE.447911},
        year = {2022},
       type = {Journal Article}
    }
    
  • von der Burchard, C;Sudkamp, H;Tode, J;Ehlken, C;Purtskhvanidze, K;Moltmann, M;Heimes, B;Koch, P;Münst, M;vom Endt, M;Kepp, T;Theisen-Kunde, D;König, I;Hüttmann, G and Roider, J: Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study. BMJ Open, no. 12, pp. e055082, 2022
    BibTeX Link Link
    @article{von der Burchardt2022,
       author = {von der Burchard, C;Sudkamp, H;Tode, J;Ehlken, C;Purtskhvanidze, K;Moltmann, M;Heimes, B;Koch, P;Münst, M;vom Endt, M;Kepp, T;Theisen-Kunde, D;König, I;Hüttmann, G and Roider, J},
       title = {Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study},
       journal = {BMJ Open},
       volume = {12},
       number = {6},
       pages = {e055082},
       DOI = {10.1136/bmjopen-2021-055082},
       url = {http://bmjopen.bmj.com/content/12/6/e055082.abstract},
       year = {2022},
       type = {Journal Article}
    }
    
  • Strenge, P;Lange, B;Grill, C;Draxinger, W;Danicke, V;Theisen-Kunde, D;Hagel, C;Spahr-Hess, S;Bonsanto, Matteo M.;Huber, R;Handels, H and Brinkmann, R: Registration of histological brain images onto optical coherence tomography images based on shape information. Physics in Medicine & Biology, 2022
    BibTeX Link
    @article{Strenge2022,
       author = {Strenge, P;Lange, B;Grill, C;Draxinger, W;Danicke, V;Theisen-Kunde, D;Hagel, C;Spahr-Hess, S;Bonsanto, Matteo M.;Huber, R;Handels, H and Brinkmann, R},
       title = {Registration of histological brain images onto optical coherence tomography images based on shape information},
    keywords = {brain, glioblastoma multiforme, shape, OCT, optical coherence tomography, AG-Huber_OCT,},
       journal = {Physics in Medicine & Biology},
       ISSN = {0031-9155},
       url = {http://iopscience.iop.org/article/10.1088/1361-6560/ac6d9d},
       year = {2022},
       type = {Journal Article}
    }
    
  • Liang, X-X and Vogel, A: Probing neuronal functions with precise and targeted laser ablation in the living cortex: comment. Optica, no. 9(8), pp. 868-871, 2022
    BibTeX Link
    @article{Liang2022,
       author = {Liang, X-X and Vogel, A},
       title = {Probing neuronal functions with precise and targeted laser ablation in the living cortex: comment},
       journal = {Optica},
       volume = {9(8)},
       keywords = {Attenuation coefficient, Femtosecond lasers, Laser ablation, Laser irradiation, Numerical simulation, Thermal effects},
       pages = {868-871},
       DOI = {10.1364/OPTICA.454469},  
       year = {2022},
       type = {Journal Article}
    }
    
  • Pfäffle, C;Spahr, H;Gercke, K;Puyo, L;Höhl, S;Melenberg, D;Miura, Y;Hüttmann, G and Hillmann, D: Phase-Sensitive Measurements of Depth-Dependent Signal Transduction in the Inner Plexiform Layer. Frontiers in Medicine, no. 9, 2022
    BibTeX Link Link
    @article{RN5328,
       author = {Pfäffle, C;Spahr, H;Gercke, K;Puyo, L;Höhl, S;Melenberg, D;Miura, Y;Hüttmann, G and Hillmann, D},
       title = {Phase-Sensitive Measurements of Depth-Dependent Signal Transduction in the Inner Plexiform Layer},
       journal = {Frontiers in Medicine},
       volume = {9},
       ISSN = {2296-858X},
       DOI = {10.3389/fmed.2022.885187},
    keywords = {optoretinography, optical coherence tomography, phase-sensitive OCT, functional imaging, inner
    plexiform layer, retina},
       url = {https://www.frontiersin.org/articles/10.3389/fmed.2022.885187},
       year = {2022},
       type = {Journal Article}
    }
    
  • Schaller, M;Wilson, M;Kleyman, V;Mordmüller, M;Brinkmann, R;Müller, M. A. and Worthmann, K: Parameter estimation and model reduction for model predictive control in retinal laser treatment. Control Engineering Practice, no. 128, pp. 105320, 2022
    BibTeX Link
    @article{Schaller2022,
       author = {Schaller, M;Wilson, M;Kleyman, V;Mordmüller, M;Brinkmann, R;Müller, M. A. and Worthmann, K},
       title = {Parameter estimation and model reduction for model predictive control in retinal laser treatment},
       journal = {Control Engineering Practice},
       volume = {128},
       pages = {105320},
       ISSN = {0967-0661},
       DOI = {https://doi.org/10.1016/j.conengprac.2022.105320},
    
       year = {2022},
       type = {Journal Article}
    }
    
  • Yashin, K;Bonsanto, M M;Achkasova, K;Zolotova, A;Wael, Al-M;Kiseleva, E;Moiseev, A;Medyanik, I;Kravets, L;Huber, R;Brinkmann, R and Gladkova, N: OCT-Guided Surgery for Gliomas: Current Concept and Future Perspectives. Diagnostics, no. 12, pp. 335, 2022
    BibTeX Link
    @article{Yashin 2022,
       author = {Yashin, K;Bonsanto, M M;Achkasova, K;Zolotova, A;Wael, Al-M;Kiseleva, E;Moiseev, A;Medyanik, I;Kravets, L;Huber, R;Brinkmann, R and Gladkova, N},
       title = {OCT-Guided Surgery for Gliomas: Current Concept and Future Perspectives},
       journal = {Diagnostics},
       volume = {12},
       number = {2},
       pages = {335},
       ISSN = {2075-4418},
    keywords = {AG-Huber; optical coherence tomography; brain imaging; neurosurgical guidance; brain tumor; minimally invasive theranostics; intraoperative imaging},
       url = {https://www.mdpi.com/2075-4418/12/2/335},
       year = {2022},
       type = {Journal Article}
    }
    
  • Schaller, M.;Kleyman, K.;Mordmüller, M.;Schmidt, C.;Wilson, M.;Brinkmann, R.;Müller, M.A. and Worthmann, K.: Model predictive control for retinal laser treatment at 1 kHz. at - Automatisierungstechnik, no. 70(11), pp. 992-1002, 2022
    BibTeX Link
    @article{Schaller2022,
       author = {Schaller, M.;Kleyman, K.;Mordmüller, M.;Schmidt, C.;Wilson, M.;Brinkmann, R.;Müller, M.A. and Worthmann, K.},
       title = {Model predictive control for retinal laser treatment at 1 kHz},
       journal = {at - Automatisierungstechnik},
       volume = {70(11)},
       keywords = {model predictive control; real-time control;retinal photocoagulation},
       pages = {992-1002},
      
       url = {https://doi.org/10.1515/auto-2022-0030},
       year = {2022},
       type = {Journal Article}
    }
    
  • Freidank, S;Vogel, A and Linz, N: Mechanisms of corneal intrastromal laser dissection for refractive surgery: ultra-high-speed photographic investigation at up to 50 million frames per second. BioOptExpr, no. 13 (5), pp. 3056-3079, 2022
    BibTeX Link
    @article{Freidank2022,
       author = {Freidank, S;Vogel, A and Linz, N},
       title = {Mechanisms of corneal intrastromal laser dissection for refractive surgery: ultra-high-speed photographic investigation at up to 50 million frames per second},
       journal = {BioOptExpr},
       volume = {13 (5)},
       
       pages = {3056-3079},
       DOI = {10.1364/BOE.455926},
    
       year = {2022},
       type = {Journal Article}
    }
    
  • Kohlfaerber, T;Pieper, M;Münter, M;Holzhausen, C;Ahrens, M;Idel, C;Bruchhage, K-L;Leichtle, A;König, P;Hüttmann, G and Schulz-Hildebrandt, H: Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways. Biomedical Optics Express, no. 13 (6), pp. 3211-3223, 2022
    BibTeX Link
    @article{Kohlfarber2022,
       author = {Kohlfaerber, T;Pieper, M;Münter, M;Holzhausen, C;Ahrens, M;Idel, C;Bruchhage, K-L;Leichtle, A;König, P;Hüttmann, G and Schulz-Hildebrandt, H},
       title = {Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways},
       journal = {Biomedical Optics Express},
       volume = {13 (6)},
      Keywords = {,
       pages = {3211-3223},
       DOI = {10.1364/BOE.456104},
      
       year = {2022},
       type = {Journal Article}
    }
    
  • Musial, G;Kohlfaerber, T;Ahrens, M;Schulz-Hildebrandt, H;Steven, P and Hüttmann, G: Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride. Translational Vision Science & Technology, no. 11(5), pp. 28-28, 2022
    BibTeX Link Link
    @article{Musial 2022,
       author = {Musial, G;Kohlfaerber, T;Ahrens, M;Schulz-Hildebrandt, H;Steven, P and Hüttmann, G},
       title = {Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride},
       journal = {Translational Vision Science & Technology},
    keywords = {toxicity; optical coherence tomography; benzalkonium chloride},
       volume = {11(5)},
       
       pages = {28-28},
       ISSN = {2164-2591},
       DOI = {10.1167/tvst.11.5.28},
       url = {https://doi.org/10.1167/tvst.11.5.28},
       year = {2022},
       type = {Journal Article}
    }
    
  • Strenge, P.;Lange, B.;Grill,C.;Danicke,V.;Theisen-Kunde, D.;Hagel, C.;Spahr-Hess, S.;;Bonsanto, Matteo M.;Handels, H.; and Huber, R.;Brinkmann, R.: Differentiation of different stages of brain tumor infiltration using optical coherence tomography: Comparison of two systems and histology. Frontiers in Oncology, 2022
    BibTeX Link Link
    @article{Strenge 2022,
       author = {Strenge, P.;Lange, B.;Grill,C.;Danicke,V.;Theisen-Kunde, D.;Hagel, C.;Spahr-Hess, S.;;Bonsanto, Matteo M.;Handels, H.; and Huber, R.;Brinkmann, R.},
       title = {Differentiation of different stages of brain tumor infiltration using optical coherence tomography: Comparison of two systems and histology},
       journal = {Frontiers in Oncology},
    Keywords = {AG-Huber_FDML, AG-Huber_OCT, brain, tumor, glioblastoma multiforme, OCT, neural network, attenuation (absorption)
    coefficient, optical coherence tomography},
       DOI = {https://doi.org/10.3389/fonc.2022.896060},
       url = {https://www.frontiersin.org/articles/10.3389/fonc.2022.896060/full},
       year = {2022},
       type = {Journal Article}
    }
    
  • M. Goodwin, M. Klufts, J. Workman, A. Thambyah and F. Vanholsbeeck: Detection of subtle cartilage and bone tissue degeneration in the equine joint using polarisation-sensitive optical coherence tomography. Osteoarthritis and Cartilage, 2022
    BibTeX Link
    @article{GOODWIN2022,
    title = {Detection of subtle cartilage and bone tissue degeneration in the equine joint using polarisation-sensitive optical coherence tomography},
    journal = {Osteoarthritis and Cartilage},
    year = {2022},
    issn = {1063-4584},
    doi = {https://doi.org/10.1016/j.joca.2022.04.006},
    author = {M. Goodwin, M. Klufts, J. Workman, A. Thambyah and F. Vanholsbeeck},
    keywords = {Optical coherence tomography, Polarisation-sensitive optical coherence tomography, Osteoarthritis},
    abstract = {Summary
    Objective
    To explore the ability of polarisation-sensitive optical coherence tomography (PS-OCT) to rapidly identify subtle signs of tissue degeneration in the equine joint.
    Method
    Polarisation-sensitive optical coherence tomography (PS-OCT) images were systematically acquired in four locations along the medial and lateral condyles of the third metacarpal bone in five dissected equine specimens. Intensity and retardation PS-OCT images, and anomalies observed therein, were then compared and validated with high resolution images of the tissue sections obtained using Differential Interference contrast (DIC) optical light microscopy.
    Results
    The PS-OCT system was capable of imaging the entire equine osteochondral unit, and allowed delineation of the three structurally differentiated zones of the joint, that is, the articular cartilage matrix, zone of calcified cartilage and underlying subchondral bone. Importantly, PS-OCT imaging was able to detect underlying matrix and bone changes not visible without dissection and/or microscopy.
    Conclusion
    PS-OCT has substantial potential to detect, non-invasively, sub-surface microstructural changes that are known to be associated with the early stages of joint tissue degeneration.}
    }
  • M. Göb, T. Pfeiffer, W. Draxinger, S. Lotz, J.P. Kolb and R. Huber: Continuous spectral zooming for in vivo live 4D-OCT with MHz A-scan rates and long coherence. Biomed. Opt. Express, no. 13, pp. 713-727, OSA, Feb, 2022
    BibTeX Link
    @article{Goeb2022,
    author = {M. G\"{o}b, T. Pfeiffer,  W. Draxinger, S. Lotz, J.P. Kolb and R. Huber},
    journal = {Biomed. Opt. Express},
    keywords = {AG-Huber_OCT;AG-Huber_FDML; High speed imaging; Image processing; Image quality; In vivo imaging; Range imaging; Vertical cavity surface emitting lasers},
    number = {2},
    pages = {713--727},
    publisher = {OSA},
    title = {Continuous spectral zooming for in vivo live 4D-OCT with MHz A-scan rates and long coherence},
    volume = {13},
    month = {Feb},
    year = {2022},
    doi = {10.1364/BOE.448353},
    abstract = {We present continuous three-dimensional spectral zooming in live 4D-OCT using a home-built FDML based OCT system with 3.28 MHz A-scan rate. Improved coherence characteristics of the FDML laser allow for imaging ranges up to 10 cm. For the axial spectral zoom feature, we switch between high resolution and long imaging range by adjusting the sweep range of our laser. We present a new imaging setup allowing for synchronized adjustments of the imaging range and lateral field of view during live OCT imaging. For this, a novel inline recalibration algorithm was implemented that enables numerical k-linearization of the raw OCT fringes for every frame instead of every volume. This is realized by acquiring recalibration data within the dead time of the raster scan at the turning points of the fast axis scanner. We demonstrate in vivo OCT images of fingers and hands at different resolution modes and show real three-dimensional zooming during live 4D-OCT. A three-dimensional spectral zooming feature for live 4D-OCT is expected to be a useful tool for a wide range of biomedical, scientific and research applications, especially in OCT guided surgery.},
    }
    
    
  • Liang, X-X;Linz, N;Freidank, S;Paltauf, G and Vogel, A: Comprehensive analysis of spherical bubble oscillations and shock wave emission in laser-induced cavitation. Journal of Fluid Mechanics, no. 940, pp. A5, 2022
    BibTeX Link
    @article{Liang2022,
       author = {Liang, X-X;Linz, N;Freidank, S;Paltauf, G and Vogel, A},
       title = {Comprehensive analysis of spherical bubble oscillations and shock wave emission in laser-induced cavitation},
    keywords = {bubble dynamics, cavitation, shock waves}
       journal = {Journal of Fluid Mechanics},
       volume = {940},
       pages = {A5},
       ISSN = {0022-1120},
       DOI = {10.1017/jfm.2022.202},
      
       year = {2022},
       type = {Journal Article}
    }