Marie Klufts

Doktorandin / PhD Student


Universität zu Lübeck
Institut für Biomedizinische Optik

Maria-Goeppert-Str. 1
23562 Lübeck
Gebäude MFC 1, Raum 2.24

Email:
Phone:
+49 451 3101 3234
Fax:
+49 451 3101 3204



Publications

2022

  • M. Klufts, S. Lotz, M. Bashir, S. Karpf and R. Huber: Ultra-high-accuracy chromatic dispersion measurement in optical fibers. in Optical Components and Materials XIX, no. 11997, pp. 146 - 152, SPIE, 2022
    BibTeX Link
    @inproceedings{Klufts2022,
    author = {M. Klufts, S. Lotz, M. Bashir, S. Karpf and R. Huber},
    title = {{Ultra-high-accuracy chromatic dispersion measurement in optical fibers}},
    volume = {11997},
    booktitle = {Optical Components and Materials XIX},
    editor = {Shibin Jiang and Michel J. F. Digonnet},
    organization = {International Society for Optics and Photonics},
    publisher = {SPIE},
    pages = {146 -- 152},
    keywords = {AG-Huber_FDML, Dispersion measurement, Chromatic dispersion, fiber dispersion measurement, optical component characterization, tunable laser, FDML},
    year = {2022},
    
    url = {https://zenodo.org/record/6406367#.YkcF3TWxX8A},
    }
    
  • M. Goodwin, M. Klufts, J. Workman, A. Thambyah and F. Vanholsbeeck: Detection of subtle cartilage and bone tissue degeneration in the equine joint using polarisation-sensitive optical coherence tomography. Osteoarthritis and Cartilage, 2022
    BibTeX Link
    @article{GOODWIN2022,
    title = {Detection of subtle cartilage and bone tissue degeneration in the equine joint using polarisation-sensitive optical coherence tomography},
    journal = {Osteoarthritis and Cartilage},
    year = {2022},
    issn = {1063-4584},
    doi = {https://doi.org/10.1016/j.joca.2022.04.006},
    author = {M. Goodwin, M. Klufts, J. Workman, A. Thambyah and F. Vanholsbeeck},
    keywords = {Optical coherence tomography, Polarisation-sensitive optical coherence tomography, Osteoarthritis},
    abstract = {Summary
    Objective
    To explore the ability of polarisation-sensitive optical coherence tomography (PS-OCT) to rapidly identify subtle signs of tissue degeneration in the equine joint.
    Method
    Polarisation-sensitive optical coherence tomography (PS-OCT) images were systematically acquired in four locations along the medial and lateral condyles of the third metacarpal bone in five dissected equine specimens. Intensity and retardation PS-OCT images, and anomalies observed therein, were then compared and validated with high resolution images of the tissue sections obtained using Differential Interference contrast (DIC) optical light microscopy.
    Results
    The PS-OCT system was capable of imaging the entire equine osteochondral unit, and allowed delineation of the three structurally differentiated zones of the joint, that is, the articular cartilage matrix, zone of calcified cartilage and underlying subchondral bone. Importantly, PS-OCT imaging was able to detect underlying matrix and bone changes not visible without dissection and/or microscopy.
    Conclusion
    PS-OCT has substantial potential to detect, non-invasively, sub-surface microstructural changes that are known to be associated with the early stages of joint tissue degeneration.}
    }

2021

  • F. Vanholsbeeck, M. Goodwin, M. Klufts, J. Workman and A. Thambyah: Birefringence as a proxy for viscoelastic properties of cartilage using polarisation sensitive optical coherence tomography. in Optical Elastography and Tissue Biomechanics VIII, no. 11645, SPIE, 2021
    BibTeX Link
    @inproceedings{10.1117/12.2587181,
    author = {F. Vanholsbeeck, M. Goodwin, M. Klufts, J. Workman and A. Thambyah},
    title = {{Birefringence as a proxy for viscoelastic properties of cartilage using polarisation sensitive optical coherence tomography}},
    volume = {11645},
    booktitle = {Optical Elastography and Tissue Biomechanics VIII},
    editor = {Kirill V. Larin and Giuliano Scarcelli},
    organization = {International Society for Optics and Photonics},
    publisher = {SPIE},
    abstract = {Non-invasive identification, understanding and evaluation of articular cartilage damage is paramount for osteoarthritis researcher and clinician alike. Using polarisation sensitive optical coherence tomography together with impact and creep load, we use a range of metrics including birefringence to detect early signs of cartilage degeneration and gain new insights into the physiology of joint tissues},
    year = {2021},
    doi = {10.1117/12.2587181},
    }